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phenyl biguanide and Anesthesia

phenyl biguanide has been researched along with Anesthesia in 21 studies

phenyl biguanide: RN given refers to parent cpd
phenyl biguanide : A member of the class of biguanides that is biguanide in which one of the terminal nitrogen atoms is substituted by a phenyl group.

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research Excerpts

ExcerptRelevanceReference
" The role of central 5-HT(1A) receptors in the control of the bradycardia and changes in central respiratory drive, renal nerve activity and blood pressure evoked by stimulating cardiopulmonary afferents with phenylbiguanide, baroreceptors by electrical stimulation of the aortic nerve and chemoreceptors by injections of sodium cyanide (NaCN) in atenolol-pretreated anaesthetized rabbits were studied."3.71Modulation of reflexly evoked vagal bradycardias by central 5-HT1A receptors in anaesthetized rabbits. ( Jordan, D; Ramage, AG; Skinner, MR, 2002)
" The response to bolus injection of PDG into the right atrium was qualitatively similar to the one seen in cats under anesthesia, consisting of bradycardia and apnea followed by rapid shallow breathing (RSB)."3.67The respiratory response to stimulation of juxta-pulmonary capillary receptors in the non-anesthetized cat. ( Ginzel, KH; Lucas, EA, 1985)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19904 (19.05)18.7374
1990's9 (42.86)18.2507
2000's7 (33.33)29.6817
2010's1 (4.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pant, J1
Pant, MK1
Deshpande, SB2
Skinner, MR1
Ramage, AG5
Jordan, D4
Kellett, DO1
Stanford, SC1
Machado, BH1
Lee, LY1
Lundberg, JM1
Paton, JF3
Butcher, JW1
Silva-Carvalho, L1
Rocha, I1
Goldsmith, GE1
Spyer, KM1
Wang, Y2
Bagchi, S1
Brophy, S1
Ford, TW1
Carey, M1
Jones, JF3
Veelken, R1
Hilgers, KF1
Scrogin, KE1
Mann, JF1
Schmieder, RE1
Yu, YH1
Blessing, WW1
Jeggo, RD1
de Burgh Daly, M1
Edwards, E1
Wacker, MJ1
Tehrani, RN1
Smoot, RL1
Orr, JA1
Kilpatrick, GJ1
Butler, A1
Burridge, J1
Oxford, AW1
Bogle, RG1
Pires, JG1
Balzamo, E1
Jammes, Y1
Adams, L1
Schneider, DA1
Schertel, ER1
Strong, EB1
Green, JF1
Trenchard, D1
Ginzel, KH1
Lucas, EA1

Other Studies

21 other studies available for phenyl biguanide and Anesthesia

ArticleYear
Bisphenol A attenuates phenylbiguanide-induced cardio-respiratory reflexes in anaesthetized rats.
    Neuroscience letters, 2012, Nov-14, Volume: 530, Issue:1

    Topics: Air Pollutants, Occupational; Analgesics; Anesthesia; Animals; Benzhydryl Compounds; Biguanides; Blo

2012
Modulation of reflexly evoked vagal bradycardias by central 5-HT1A receptors in anaesthetized rabbits.
    British journal of pharmacology, 2002, Volume: 137, Issue:6

    Topics: Anesthesia; Animals; Atenolol; Biguanides; Blood Pressure; Bradycardia; Buspirone; Chemoreceptor Cel

2002
Effect of 5-HT depletion on cardiovascular vagal reflex sensitivity in awake and anesthetized rats.
    Brain research, 2005, Aug-23, Volume: 1054, Issue:1

    Topics: Adrenergic alpha-Agonists; Anesthesia; Animals; Baroreflex; Biguanides; Biogenic Monoamines; Blood P

2005
Capsazepine abolishes pulmonary chemoreflexes induced by capsaicin in anesthetized rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 76, Issue:5

    Topics: Anesthesia; Animals; Biguanides; Capsaicin; Chemoreceptor Cells; Female; Lung; Male; Nerve Fibers; N

1994
Cardiorespiratory reflexes in mice.
    Journal of the autonomic nervous system, 1998, Jan-19, Volume: 68, Issue:1-2

    Topics: Anesthesia; Animals; Baroreflex; Biguanides; Chemoreceptor Cells; Female; Heart; Heart Rate; In Vitr

1998
Convergence properties of solitary tract neurons responsive to cardiac receptor stimulation in the anesthetized cat.
    Journal of neurophysiology, 1998, Volume: 79, Issue:5

    Topics: Afferent Pathways; Anesthesia; Animals; Biguanides; Bradycardia; Carotid Body; Carotid Sinus; Cats;

1998
Presynaptic 5-HT3 receptors evoke an excitatory response in dorsal vagal preganglionic neurones in anaesthetized rats.
    The Journal of physiology, 1998, Jun-15, Volume: 509 ( Pt 3)

    Topics: 2-Amino-5-phosphonovalerate; Anesthesia; Animals; Biguanides; Cadmium; Excitatory Amino Acid Agonist

1998
Indian red scorpion (Buthus tamulus) venom-induced augmentation of cardiac reflexes is mediated through the mechanisms involving kinins in urethane anaesthetized rats.
    Toxicon : official journal of the International Society on Toxinology, 1998, Volume: 36, Issue:2

    Topics: Analgesics; Anesthesia; Animals; Antihypertensive Agents; Aprotinin; Biguanides; Captopril; Drug Syn

1998
Activity of aortic chemoreceptors in the anaesthetized rat.
    The Journal of physiology, 1999, Feb-01, Volume: 514 ( Pt 3)

    Topics: Anesthesia; Animals; Aorta, Thoracic; Biguanides; Blood Pressure; Chemoreceptor Cells; Electric Stim

1999
Endogenous angiotensin II and the reflex response to stimulation of cardiopulmonary serotonin 5HT3 receptors.
    British journal of pharmacology, 1998, Volume: 125, Issue:8

    Topics: Anesthesia; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibito

1998
Carotid and cardiopulmonary chemoreceptor activity increases hippocampal theta rhythm in conscious rabbits.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 278, Issue:4

    Topics: Anesthesia; Animals; Arousal; Biguanides; Carotid Artery, Common; Carotid Body; Carotid Sinus; Chemo

2000
Aortic body chemoreflex of the anaesthetized rat. Electrophysiological, morphological, and reflex studies.
    Advances in experimental medicine and biology, 2000, Volume: 475

    Topics: Almitrine; Anesthesia; Animals; Aortic Bodies; Biguanides; Blood Pressure; Chemoreceptor Cells; Elec

2000
Effect of pulmonary C-fibre afferent stimulation on cardiac vagal neurones in the nucleus ambiguus in anaesthetized cats.
    The Journal of physiology, 2000, Jul-01, Volume: 526 Pt 1

    Topics: Action Potentials; Anesthesia; Animals; Autonomic Fibers, Preganglionic; Axons; Biguanides; Bradycar

2000
Glutamate stimulation of raphe pallidus attenuates the cardiopulmonary reflex in anaesthetised rats.
    Autonomic neuroscience : basic & clinical, 2000, Aug-14, Volume: 82, Issue:3

    Topics: Anesthesia; Animals; Biguanides; Blood Pressure; Bradycardia; Glutamic Acid; Heart Rate; Male; Micro

2000
Thromboxane A(2) mimetic evokes a bradycardia mediated by stimulation of cardiac vagal afferent nerves.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Anesthesia; Animals; Biguanides;

2002
1-(m-chlorophenyl)-biguanide, a potent high affinity 5-HT3 receptor agonist.
    European journal of pharmacology, 1990, Jun-21, Volume: 182, Issue:1

    Topics: Anesthesia; Animals; Biguanides; Binding, Competitive; Cats; Heart Rate; Imidazoles; In Vitro Techni

1990
Evidence that central 5-HT1A-receptors play a role in the von Bezold-Jarisch reflex in the rat.
    British journal of pharmacology, 1990, Volume: 100, Issue:4

    Topics: Anesthesia; Animals; Atenolol; Biguanides; Blood Pressure; Drug Interactions; Heart; Heart Rate; Mal

1990
Vagal afferents and EEG rhythms in the Sl area in anesthetized cats: similarities between responses to electrical and chemical (phenyldiguanide) stimulations.
    Archives internationales de physiologie et de biochimie, 1989, Volume: 97, Issue:6

    Topics: Afferent Pathways; Anesthesia; Animals; Biguanides; Brain; Cats; Electric Stimulation; Electroenceph

1989
Respiratory reflexes in the anesthetized miniature swine.
    Respiration physiology, 1987, Volume: 70, Issue:3

    Topics: Anesthesia; Animals; Biguanides; Capsaicin; Carbon Dioxide; Female; Hemodynamics; Male; Physical Sti

1987
Chemoreflexes in rabbits.
    Respiration physiology, 1986, Volume: 66, Issue:3

    Topics: Acids; Anesthesia; Animals; Biguanides; Cardiovascular System; Chemoreceptor Cells; Hydroxy Acids; K

1986
The respiratory response to stimulation of juxta-pulmonary capillary receptors in the non-anesthetized cat.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:1A

    Topics: Anesthesia; Animals; Aorta; Apnea; Arousal; Biguanides; Capillaries; Cats; Dose-Response Relationshi

1985