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phenyl acetate and Hyperammonemia

phenyl acetate has been researched along with Hyperammonemia in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.56)18.2507
2000's10 (55.56)29.6817
2010's7 (38.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bukofzer, S; Clasen, K; Durkalski, V; Fontana, RJ; Ganger, D; Gottfried, M; Hameed, B; Hanje, AJ; Koch, D; Lee, WM; Little, L; Ravis, WR; Sherker, A; Stravitz, RT; Subramanian, RM1
Arenas, YM; Cabrera-Pastor, A; Felipo, V; Taoro-Gonzalez, L1
Breuer, M; Carl, M; Hoffmann, GF; Kölker, S; Okun, JG; Zielonka, M1
Dasarathy, S; Eghtesad, B; McDonald, C; Mohan, ML; Mozdziak, PE; Naga Prasad, SV; Narayanan, A; Qiu, J; Runkana, A; Stark, GR; Thapaliya, S; Tsien, C; Welle, S; Yang, Y1
Carvalho, RV; da Silva Ferreira, F; Fernandes, C; Heimfarth, L; Pessoa-Pureur, R; Pierozan, P1
Li, M; Meng, F; Ren, Q; Shi, G; Song, M; Wang, R; Xing, X; Yuan, L1
Cant, JP; Cieslar, SR; Madsen, TG; Poppi, DP; Purdie, NG; Trout, DR1
Cadena, M; Cervera, E; de Hoyos, A; Gil, S; Poo, JL; Uribe, M1
Kaminsky, Y; Kosenko, E1
Grzeda, E; Wiśniewska, RJ1
Bak, LK; Dadsetan, S; Jalan, R; Keiding, S; Ott, P; Schousboe, A; Sørensen, M; Vilstrup, H; Waagepetersen, HS1
Dakshayani, KB; Subramanian, P; Velvizhi, S2
Ivnitsky, JJ; Malakhovsky, VN; Rejniuk, VL; Schäfer, TV1
Albrecht, J; Felipo, V; Fresko, I; Konopacka, A; Zielińska, M1
Ivnitsky, JJ; Ovsep'yan, RV; Rejniuk, VL; Schafer, TV1
Behar, KL; Cline, GW; Herskovits, AZ; Mason, GF; Rothman, DL; Shen, J; Shulman, RG; Sibson, NR; Wall, JE1
Behar, KL; Rothman, DL1

Reviews

2 review(s) available for phenyl acetate and Hyperammonemia

ArticleYear
[Rationale for the use of sodium benzoate in clinical hepatology].
    Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion, 1990, Volume: 42 Suppl

    Topics: Acetates; Adult; Animals; Child; Clinical Trials as Topic; Drug Evaluation, Preclinical; Glycine; Hepatic Encephalopathy; Hippurates; Humans; Hyperammonemia; Liver Cirrhosis; Liver Function Tests; Male; Metabolism, Inborn Errors; Mice; Molecular Structure; Rats; Sodium Benzoate; Urea

1990
In vivo nuclear magnetic resonance studies of glutamate-gamma-aminobutyric acid-glutamine cycling in rodent and human cortex: the central role of glutamine.
    The Journal of nutrition, 2001, Volume: 131, Issue:9 Suppl

    Topics: Acetates; Animals; Astrocytes; Biological Transport; Blood-Brain Barrier; Carbon Isotopes; Cerebral Cortex; Disease Models, Animal; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Humans; Hyperammonemia; Magnetic Resonance Spectroscopy; Neurons; Nitrogen Isotopes; Rats

2001

Other Studies

16 other study(ies) available for phenyl acetate and Hyperammonemia

ArticleYear
Safety, tolerability, and pharmacokinetics of l-ornithine phenylacetate in patients with acute liver injury/failure and hyperammonemia.
    Hepatology (Baltimore, Md.), 2018, Volume: 67, Issue:3

    Topics: Acetates; Adolescent; Adult; Aged; Ammonia; Female; Glutamine; Humans; Hyperammonemia; Kidney Function Tests; Liver; Liver Failure, Acute; Male; Middle Aged; Ornithine; Phenols; Registries; Treatment Outcome; Young Adult

2018
Hyperammonemia alters membrane expression of GluA1 and GluA2 subunits of AMPA receptors in hippocampus by enhancing activation of the IL-1 receptor: underlying mechanisms.
    Journal of neuroinflammation, 2018, Feb-08, Volume: 15, Issue:1

    Topics: Acetates; Animals; Cell Membrane; Gene Expression; Hippocampus; Hyperammonemia; Interleukin 1 Receptor Antagonist Protein; Male; Protein Subunits; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Interleukin-1 Type I

2018
Pharmacologic rescue of hyperammonemia-induced toxicity in zebrafish by inhibition of ornithine aminotransferase.
    PloS one, 2018, Volume: 13, Issue:9

    Topics: Acetates; Animals; Hyperammonemia; Ornithine; Ornithine-Oxo-Acid Transaminase; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Zebrafish

2018
Hyperammonemia in cirrhosis induces transcriptional regulation of myostatin by an NF-κB-mediated mechanism.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Nov-05, Volume: 110, Issue:45

    Topics: Acetates; Animals; Chromatin Immunoprecipitation; Electrophoretic Mobility Shift Assay; Gene Expression Regulation; Humans; Hyperammonemia; Immunoblotting; Liver Cirrhosis; Mice; Mice, Knockout; Microscopy, Confocal; Muscle Fibers, Skeletal; Myostatin; NF-kappa B; Real-Time Polymerase Chain Reaction

2013
Acute Hyperammonemia Induces NMDA-Mediated Hypophosphorylation of Intermediate Filaments Through PP1 and PP2B in Cerebral Cortex of Young Rats.
    Neurotoxicity research, 2016, Volume: 30, Issue:2

    Topics: Acetates; Aging; Ammonium Chloride; Animals; Astrocytes; Calcineurin; Calcium; Calcium Signaling; Cerebral Cortex; Disease Models, Animal; Hippocampus; Hyperammonemia; Intermediate Filaments; N-Methylaspartate; Neurons; Phosphorylation; Protein Phosphatase 1; Rats, Wistar; Time Factors; Tissue Culture Techniques

2016
Acute ammonia toxicity in crucian carp Carassius auratus and effects of taurine on hyperammonemia.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2016, Volume: 190

    Topics: Acetates; Amino Acid Transport Systems; Animals; Antioxidants; Biomarkers; Brain; Fish Proteins; Goldfish; Hyperammonemia; Immune Tolerance; Lipid Peroxidation; Liver; Oxidative Stress; Taurine

2016
The effect of short-term hyperammonaemia on milk synthesis in dairy cows.
    The Journal of dairy research, 2009, Volume: 76, Issue:1

    Topics: Acetates; Amino Acids; Ammonia; Animals; Cattle; Cattle Diseases; Dairying; Eating; Female; Hyperammonemia; Lactation; Mammary Glands, Animal; Milk; Sodium Acetate

2009
Brain purine metabolism and xanthine dehydrogenase/oxidase conversion in hyperammonemia are under control of NMDA receptors and nitric oxide.
    Brain research, 2009, Oct-19, Volume: 1294

    Topics: Acetates; Animals; Brain; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hyperammonemia; Male; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Purines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Xanthine Dehydrogenase; Xanthine Oxidase

2009
Effect of the class I metabotropic glutamate receptor antagonist AIDA on certain behaviours in rats with experimental chronic hyperammonemia.
    Advances in medical sciences, 2009, Volume: 54, Issue:2

    Topics: Acetates; Animals; Anxiety; Avoidance Learning; Behavior, Animal; Chronic Disease; Excitatory Amino Acid Antagonists; Exploratory Behavior; Hyperammonemia; Indans; Injections, Intraperitoneal; Injections, Intraventricular; Locomotion; Male; Maze Learning; Mental Recall; Random Allocation; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Stress, Psychological

2009
Interorgan metabolism of ornithine phenylacetate (OP)--a novel strategy for treatment of hyperammonemia.
    Biochemical pharmacology, 2013, Jan-01, Volume: 85, Issue:1

    Topics: Acetates; Ammonia; Animals; Arteries; Bile Ducts; Drug Interactions; Female; Glutamine; Hyperammonemia; Kidney; Ligation; Liver; Liver Cirrhosis, Biliary; Muscle, Skeletal; Nitrogen Isotopes; Ornithine; Phenols; Rats; Rats, Wistar; Tissue Distribution

2013
Effects of ornithine alpha-ketoglutarate on circulatory antioxidants and lipid peroxidation products in ammonium acetate treated rats.
    Annals of nutrition & metabolism, 2002, Volume: 46, Issue:3-4

    Topics: Acetates; Analysis of Variance; Animals; Antioxidants; Ascorbic Acid; Hyperammonemia; Lipid Peroxidation; Lipids; Liver; Nitrogen; Ornithine; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Urea; Vitamin E

2002
Effects of alpha-ketoglutarate on antioxidants and lipid peroxidation products in rats treated with ammonium acetate.
    Nutrition (Burbank, Los Angeles County, Calif.), 2002, Volume: 18, Issue:9

    Topics: Acetates; Animals; Antioxidants; Body Weight; Hyperammonemia; Ketoglutaric Acids; Kidney; Lipid Peroxidation; Lipids; Liver; Male; Nitrogen; Organ Size; Random Allocation; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Urea

2002
Fulminant hyperammonaemia induced by thiopental coma in rats.
    Toxicology, 2006, Jul-25, Volume: 224, Issue:3

    Topics: Acetates; Ammonia; Animals; Blood Urea Nitrogen; Coma; Defecation; Dose-Response Relationship, Drug; Gastrointestinal Contents; Gastrointestinal Tract; Hyperammonemia; Hypnotics and Sedatives; Injections, Intraperitoneal; Intestinal Obstruction; Rats; Thiopental; Time Factors

2006
Hyperammonemia inhibits the natriuretic peptide receptor 2 (NPR-2)-mediated cyclic GMP synthesis in the astrocytic compartment of rat cerebral cortex slices.
    Neurotoxicology, 2007, Volume: 28, Issue:6

    Topics: Acetates; Aconitate Hydratase; Animals; Astrocytes; Cerebral Cortex; Cyclic GMP; Disease Models, Animal; Fluoroacetates; Guanylate Cyclase; Hyperammonemia; Male; Natriuretic Peptide, C-Type; Nitric Oxide Donors; Rats; Rats, Wistar; Receptors, Atrial Natriuretic Factor; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine

2007
Effect of atmospheric ammonia on mortality rate of rats with barbiturate intoxication.
    Bulletin of experimental biology and medicine, 2007, Volume: 143, Issue:6

    Topics: Acetates; Administration, Inhalation; Ammonia; Animals; Drug Synergism; Female; Hyperammonemia; Oxygen Consumption; Poisoning; Rats; Respiration; Thiopental

2007
In vivo (13)C NMR measurement of neurotransmitter glutamate cycling, anaplerosis and TCA cycle flux in rat brain during.
    Journal of neurochemistry, 2001, Volume: 76, Issue:4

    Topics: Acetates; Ammonia; Animals; Astrocytes; Blood Glucose; Brain; Brain Chemistry; Carbon Isotopes; Cerebral Cortex; Citric Acid Cycle; Glucose; Glutamic Acid; Glutamine; Homeostasis; Hyperammonemia; Magnetic Resonance Spectroscopy; Male; Models, Theoretical; Neurons; Rats; Rats, Sprague-Dawley

2001