Page last updated: 2024-08-23

phenyl acetate and Huntington Disease

phenyl acetate has been researched along with Huntington Disease in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19908 (72.73)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aldana, BI; Andersen, JV; Nielsen, ML; Nørremølle, A; Santos, A; Skotte, NH; Waagepetersen, HS; Willert, CW1
Garcia, RA; Hu, Z; Li, D; Liu, LS; Saydoff, JA; von Borstel, RW1
Beal, MF; Brenneman, D; Browne, SE; Burr, H; Cardin, S; Garcia, RA; Gonzalez, A; Gregorio, J; Hu, Z; Liu, L; Saydoff, JA; Sheng, J; von Borstel, RW1
Maltese, WA1
Allan, BM; Baird, PA; Hansen, S; MacLeod, PM; Perry, TL; Wright, JM1
Chase, TN; Roberts, E; Shoulson, I; Van Balgooy, JN1
Hansen, S; Perry, TL1
Avanzini, G; Caraceni, T; Giovannini, P; Girotti, F1
Hansen, S; Kennedy, J; Perry, TL; Urquhart, N1
Kelvin, AS; McNamee, B; Turnbull, MJ1
Bond, PA1

Trials

2 trial(s) available for phenyl acetate and Huntington Disease

ArticleYear
Failure of aminooxyacetic acid therapy in Huntington disease.
    Neurology, 1980, Volume: 30, Issue:7 Pt 1

    Topics: Acetates; Adult; Amino Acids; Aminooxyacetic Acid; Double-Blind Method; Female; Humans; Huntington Disease; Hydroxyproline; Isoniazid; Male; Middle Aged; Ornithine; Proline

1980
Letter: Huntington's disease: treatment with imidazole-4-acetic acid.
    The New England journal of medicine, 1975, Sep-04, Volume: 293, Issue:10

    Topics: Acetates; Adult; Clinical Trials as Topic; Esters; Female; Humans; Huntington Disease; Imidazoles; Injections, Intravenous; Male; Middle Aged

1975

Other Studies

9 other study(ies) available for phenyl acetate and Huntington Disease

ArticleYear
Integrative Characterization of the R6/2 Mouse Model of Huntington's Disease Reveals Dysfunctional Astrocyte Metabolism.
    Cell reports, 2018, 05-15, Volume: 23, Issue:7

    Topics: 3-Hydroxybutyric Acid; Acetates; Animals; Astrocytes; Brain; Disease Models, Animal; Energy Metabolism; Female; Glutamic Acid; Glutamine; Humans; Huntington Disease; Male; Mice, Transgenic; Neurotransmitter Agents; Proteome

2018
Oral uridine pro-drug PN401 decreases neurodegeneration, behavioral impairment, weight loss and mortality in the 3-nitropropionic acid mitochondrial toxin model of Huntington's disease.
    Brain research, 2003, Dec-19, Volume: 994, Issue:1

    Topics: Acetates; Administration, Oral; Animals; Huntington Disease; Male; Mice; Mitochondria; Motor Activity; Nerve Degeneration; Nitro Compounds; Prodrugs; Propionates; Uridine; Weight Loss

2003
Oral uridine pro-drug PN401 is neuroprotective in the R6/2 and N171-82Q mouse models of Huntington's disease.
    Neurobiology of disease, 2006, Volume: 24, Issue:3

    Topics: Acetates; Administration, Oral; Analysis of Variance; Animals; Cerebral Cortex; Disease Models, Animal; Female; Huntingtin Protein; Huntington Disease; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Neurologic Mutants; Mice, Transgenic; Motor Activity; Neostriatum; Nerve Degeneration; Nerve Tissue Proteins; Neuroprotective Agents; Nuclear Proteins; Prodrugs; Rotarod Performance Test; Uridine

2006
Cholesterol synthesis in cultured skin fibroblasts from patients with Huntington's disease.
    Biochemical medicine, 1984, Volume: 32, Issue:1

    Topics: Acetates; Adult; Cells, Cultured; Cholesterol; Female; Fibroblasts; Humans; Huntington Disease; Hydroxymethylglutaryl CoA Reductases; Male; Middle Aged; Phospholipids; Proteins; Skin; Water

1984
Biochemical effects in man and rat of three drugs which can increase brain GABA content.
    Journal of neurochemistry, 1978, Volume: 30, Issue:4

    Topics: Acetates; Adult; Amino Acids; Aminobutyrates; Aminooxyacetic Acid; Animals; Brain; gamma-Aminobutyric Acid; Humans; Huntington Disease; Isoniazid; Rats; Valerates; Valproic Acid

1978
Pharmacology of Huntington's chorea. Personal experience.
    European neurology, 1977, Volume: 16, Issue:1-6

    Topics: Acetates; Adult; Aminobutyrates; Blood Cell Count; Bromocriptine; Female; gamma-Aminobutyric Acid; Haloperidol; Humans; Huntington Disease; Kidney Function Tests; Liver Function Tests; Male; Middle Aged; Physostigmine; Receptors, Dopamine; Valerates; Valproic Acid

1977
Gamma-aminobutyric acid: drug-induced elevation in monkey brain.
    Journal of neurochemistry, 1974, Volume: 23, Issue:2

    Topics: Acetates; Aminobutyrates; Animals; Brain; Carbon Radioisotopes; Carboxy-Lyases; gamma-Aminobutyric Acid; Glutamates; Haplorhini; Humans; Huntington Disease; Hydroxylamines; Isoniazid; Ketoglutaric Acids; Male; Pyridoxal Phosphate; Species Specificity; Time Factors; Transaminases

1974
Urinary excretion of some monoamines and metabolites in Huntington's chorea.
    Scottish medical journal, 1971, Volume: 16, Issue:5

    Topics: Acetates; Adult; Aged; Catecholamines; Epinephrine; Female; Histamine; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Imidazoles; Male; Mandelic Acids; Middle Aged; Norepinephrine; Vanilmandelic Acid

1971
The determination of 4-hydroxy-3-methoxyphenylethylene glycol in urine and CSF using gas chromatography.
    Biochemical medicine, 1972, Volume: 6, Issue:1

    Topics: Acetates; Adult; Catechols; Chromatography, Gas; Chromatography, Ion Exchange; Dihydroxyphenylalanine; Female; Fluoroacetates; Glucuronidase; Glycols; Humans; Huntington Disease; Male; Mass Spectrometry; Methods; Parkinson Disease; Snails; Sulfatases

1972