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phenyl acetate and Encephalopathy, Hepatic

phenyl acetate has been researched along with Encephalopathy, Hepatic in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199016 (47.06)18.7374
1990's13 (38.24)18.2507
2000's1 (2.94)29.6817
2010's3 (8.82)24.3611
2020's1 (2.94)2.80

Authors

AuthorsStudies
Kamata, S; Nakadate, K1
Bové, J; Chavarria, L; Cordoba, J; García-Lezana, T; Genescà, J; Oria, M; Romero-Giménez, J; Vila, M1
Cadena, M; Cervera, E; de Hoyos, A; Gil, S; Poo, JL; Uribe, M1
Aydin, M; Delibas, N; Demirin, H; Kilbas, A; Sutcu, R; Yonden, Z1
Bak, LK; Iversen, P; Keiding, S; Leke, R; Ott, P; Portela, LV; Schousboe, A; Sørensen, M; Vilstrup, H; Waagepetersen, HS1
Hutchinson, JH; Labby, DH1
MENDELSON, JH; SCHENKER, S1
Cortesini, C; Lombardi, G; Moneti, G; Moroni, F1
Bataille, C; Duchateau, J; Reding, P1
Butterworth, RF; Giguère, JF1
Higashi, T; Nagashima, H; Shiota, T; Watanabe, A1
Hayashi, S; Nagashima, H; Obata, T; Sakata, T; Shiota, T; Takei, N; Watanabe, A1
Bengtsson, F; Bergqvist, PB; Bugge, M; Heyes, MP1
Audet, RM; Butterworth, RF; Rao, VL1
de Knegt, RJ; Gramsbergen, JB; Schalm, SW1
Albrecht, J; Hilgier, W; Januszewski, S; Kapuściński, A; Quack, G1
Hilgier, W; Olson, JE1
Chaki, H; Inui, K; Kataoka, M; Kokuba, Y; Makita, I; Matsuda, A; Sato, M1
Albrecht, J; Faff-Michalak, L1
Albrecht, J; Faff, L; Hilgier, W1
Dombro, RS; Itzhak, Y; Norenberg, MD; Roig-Cantisano, A1
Apelqvist, G; Audet, RM; Bengtsson, F; Bergqvist, PB; Butterworth, RF; Hjorth, S1
Apelqvist, G; Bengtsson, F; Bergqvist, PB; Carpenedo, R; Moroni, F1
Alexander, B; Benjamin, IS; Li, X; Preston, JE; Segal, MB; Sherwood, R1
Savdie, E1
Müting, D1
Albrecht, J; Haugvicova, R; Hilgier, W1
Carassale, GL; Carlà, V; Cortesini, C; Lombardi, G; Moroni, F; Pellegrini, D1
de Vlieger, M; Fick, TE; Schalm, SW1
Ginsberg, MD; Gutierrez, MT; Lockwood, AH; Rhoades, HM1
Chandler, MD; McCandless, DW; Sears, ES1
Looney, GA; McCandless, DW; Modak, AT; Stavinoha, WB1
Lesch, P1

Reviews

1 review(s) available for phenyl acetate and Encephalopathy, Hepatic

ArticleYear
[Rationale for the use of sodium benzoate in clinical hepatology].
    Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion, 1990, Volume: 42 Suppl

    Topics: Acetates; Adult; Animals; Child; Clinical Trials as Topic; Drug Evaluation, Preclinical; Glycine; Hepatic Encephalopathy; Hippurates; Humans; Hyperammonemia; Liver Cirrhosis; Liver Function Tests; Male; Metabolism, Inborn Errors; Mice; Molecular Structure; Rats; Sodium Benzoate; Urea

1990

Trials

1 trial(s) available for phenyl acetate and Encephalopathy, Hepatic

ArticleYear
Oral zinc supplementation improves hepatic encephalopathy. Results of a randomised controlled trial.
    Lancet (London, England), 1984, Sep-01, Volume: 2, Issue:8401

    Topics: Acetates; Acetic Acid; Administration, Oral; Blood Urea Nitrogen; Chronic Disease; Clinical Trials as Topic; Copper; Double-Blind Method; Female; Hepatic Encephalopathy; Humans; Male; Prospective Studies; Random Allocation; Trail Making Test; Zinc

1984

Other Studies

32 other study(ies) available for phenyl acetate and Encephalopathy, Hepatic

ArticleYear
Severe Acute Hepatic Dysfunction Induced by Ammonium Acetate Treatment Results in Choroid Plexus Swelling and Ventricle Enlargement in the Brain.
    International journal of molecular sciences, 2022, Feb-11, Volume: 23, Issue:4

    Topics: Acetates; Animals; Aquaporin 1; Brain Edema; Cerebral Ventricles; Choroid Plexus; Disease Models, Animal; Hepatic Encephalopathy; Lateral Ventricles; Male; Mice; Mice, Inbred C57BL

2022
Cerebellar neurodegeneration in a new rat model of episodic hepatic encephalopathy.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2017, Volume: 37, Issue:3

    Topics: Acetates; Animals; Astrocytes; Cerebellum; Disease Models, Animal; Hepatic Encephalopathy; Lipopolysaccharides; Microglia; Neurodegenerative Diseases; Neurons; Purkinje Cells; Rats

2017
Effects of ammonia and allopurinol on rat hippocampal NMDA receptors.
    Cell biochemistry and function, 2010, Volume: 28, Issue:2

    Topics: Acetates; Allopurinol; Animals; Down-Regulation; Hepatic Encephalopathy; Hippocampus; Male; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

2010
Synthesis of neurotransmitter GABA via the neuronal tricarboxylic acid cycle is elevated in rats with liver cirrhosis consistent with a high GABAergic tone in chronic hepatic encephalopathy.
    Journal of neurochemistry, 2011, Volume: 117, Issue:5

    Topics: Acetates; Ammonia; Animals; Astrocytes; Brain Chemistry; Chromatography, High Pressure Liquid; Chronic Disease; Citric Acid Cycle; Coculture Techniques; Common Bile Duct; Excitatory Amino Acids; Female; gamma-Aminobutyric Acid; Hepatic Encephalopathy; Ligation; Liver Cirrhosis; Mass Spectrometry; Mice; Neurons; Neurotransmitter Agents; Rats; Rats, Wistar

2011
STUDIES OF RAT LIVER AND KIDNEY ENZYMES. II. RESPONSE TO DIETARY PROTEIN DEFICIENCY AND REPLETION DURING CHRONIC ADMINISTRATION OF AMMONIUM ACETATE AND L-GLUTAMINE.
    The American journal of clinical nutrition, 1964, Volume: 14, Issue:5

    Topics: Acetates; Adaptation, Physiological; Ammonia; Arginine; Dietary Proteins; Enzymes; Glutamates; Glutamine; Hepatic Encephalopathy; Kidney; Kwashiorkor; Liver; Ornithine; Protein Deficiency; Rats; Research

1964
CEREBRAL ADENOSINE TRIPHOSPHATE IN RATS WITH AMMONIA-INDUCED COMA.
    The American journal of physiology, 1964, Volume: 206

    Topics: Acetates; Adenosine Triphosphate; Ammonia; Ammonium Compounds; Antioxidants; Brain Chemistry; Cerebral Cortex; Coma; Fluorometry; Hepatic Encephalopathy; Luciferases; Luminescence; Metabolism; Quaternary Ammonium Compounds; Rats; Research; Toxicology

1964
The release and neosynthesis of glutamic acid are increased in experimental models of hepatic encephalopathy.
    Journal of neurochemistry, 1983, Volume: 40, Issue:3

    Topics: Acetates; Animals; Cerebral Cortex; Disease Models, Animal; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamic Acid; Hepatic Encephalopathy; Male; Rats; Rats, Inbred Strains

1983
Amino acid changes in regions of the CNS in relation to function in experimental portal-systemic encephalopathy.
    Neurochemical research, 1984, Volume: 9, Issue:9

    Topics: Acetates; Amino Acids; Animals; Aspartic Acid; Central Nervous System; Glutamates; Glutamic Acid; Glutamine; Hepatic Encephalopathy; Male; Portasystemic Shunt, Surgical; Rats; Rats, Inbred Strains

1984
Prevention of methionine and ammonia-induced coma by intravenous infusion of a branched chain amino acid solution to rats with liver injury.
    Acta medica Okayama, 1984, Volume: 38, Issue:5

    Topics: Acetates; Amino Acids; Amino Acids, Branched-Chain; Animals; Brain Chemistry; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Hepatic Encephalopathy; Male; Methionine; Rats; Rats, Inbred Strains

1984
Effects of intraduodenal feeding of a branched-chain amino acid-rich solution on ammonia-induced encephalopathy in liver-injured rats.
    Gastroenterologia Japonica, 1982, Volume: 17, Issue:6

    Topics: Acetates; Acute Disease; Amino Acids, Branched-Chain; Animals; Brain Diseases; Carbon Tetrachloride Poisoning; Duodenum; Hepatic Encephalopathy; Liver Cirrhosis, Experimental; Male; Rats; Rats, Inbred Strains

1982
Brain quinolinic acid in chronic experimental hepatic encephalopathy: effects of an exogenous ammonium acetate challenge.
    Journal of neurochemistry, 1995, Volume: 65, Issue:5

    Topics: Acetates; Animals; Brain; Chronic Disease; Hepatic Encephalopathy; Male; Quinolinic Acid; Rats; Rats, Sprague-Dawley

1995
Selective alterations of extracellular brain amino acids in relation to function in experimental portal-systemic encephalopathy: results of an in vivo microdialysis study.
    Journal of neurochemistry, 1995, Volume: 65, Issue:3

    Topics: Acetates; Alanine; Amino Acids; Animals; Brain; Dialysis; Extracellular Space; Frontal Lobe; Glutamine; Hepatic Encephalopathy; Kinetics; Male; Phenylalanine; Portacaval Shunt, Surgical; Rats; Rats, Sprague-Dawley; Taurine

1995
45CaCl2 autoradiography in brain from rabbits with encephalopathy from acute liver failure or acute hyperammonemia.
    Metabolic brain disease, 1994, Volume: 9, Issue:2

    Topics: Acetates; Ammonia; Animals; Autoradiography; Blood Glucose; Brain; Brain Diseases; Calcium; Calcium Radioisotopes; Hepatic Encephalopathy; Hippocampus; Liver Failure, Acute; Rabbits

1994
Increase of the brain uptake index for L-ornithine in rats with hepatic encephalopathy.
    Neuroreport, 1994, Feb-24, Volume: 5, Issue:6

    Topics: Acetates; Animals; Aspartic Acid; Blood-Brain Barrier; Brain; Endothelium; Hepatic Encephalopathy; Male; Models, Biological; Ornithine; Rats; Rats, Wistar; Thioacetamide

1994
Brain ion and amino acid contents during edema development in hepatic encephalopathy.
    Journal of neurochemistry, 1994, Volume: 62, Issue:1

    Topics: Acetates; Alanine Transaminase; Amino Acids; Ammonia; Animals; Aspartate Aminotransferases; Blood Proteins; Brain; Brain Edema; Hepatic Encephalopathy; Male; Potassium; Rats; Rats, Sprague-Dawley; Sodium; Thioacetamide

1994
[Effect of MHS-G, an amino acids granule, on hepatic encephalopathy in portacaval anastomosis rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1993, Volume: 102, Issue:6

    Topics: Acetates; Amino Acids; Animals; Brain; Electroencephalography; Hepatic Encephalopathy; Male; Portacaval Shunt, Surgical; Rats

1993
The two catalytic components of the 2-oxoglutarate dehydrogenase complex in rat cerebral synaptic and nonsynaptic mitochondria: comparison of the response to in vitro treatment with ammonia, hyperammonemia, and hepatic encephalopathy.
    Neurochemical research, 1993, Volume: 18, Issue:2

    Topics: Acetates; Ammonia; Animals; Brain; Catalysis; Hepatic Encephalopathy; In Vitro Techniques; Ketoglutarate Dehydrogenase Complex; Mitochondria; Rats; Rats, Wistar; Synapses

1993
Rat cerebral mitochondrial glutaminase activity is unaffected by moderate hyperammonemia in two models.
    Acta neurobiologiae experimentalis, 1996, Volume: 56, Issue:2

    Topics: Acetates; Animals; Brain; Citric Acid Cycle; Glutaminase; Hepatic Encephalopathy; Male; Mitochondria; Phosphates; Rats; Rats, Wistar; Thioacetamide

1996
Acute liver failure and hyperammonemia increase peripheral-type benzodiazepine receptor binding and pregnenolone synthesis in mouse brain.
    Brain research, 1995, Dec-24, Volume: 705, Issue:1-2

    Topics: Acetates; Ammonia; Animals; Brain; Disease Models, Animal; Hepatic Encephalopathy; Liver Failure, Acute; Male; Mice; Neurons; Pregnenolone; Receptors, GABA-A; Thioacetamide

1995
Ammonium acetate challenge in experimental chronic hepatic encephalopathy induces a transient increase of brain 5-HT release in vivo.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1996, Volume: 6, Issue:4

    Topics: Acetates; Animals; Brain; Hepatic Encephalopathy; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Serotonin

1996
Plasma and brain levels of oxindole in experimental chronic hepatic encephalopathy: effects of systemic ammonium acetate and L-tryptophan.
    Pharmacology & toxicology, 1999, Volume: 85, Issue:3

    Topics: Acetates; Administration, Oral; Animals; Brain; Disease Models, Animal; Hepatic Encephalopathy; Indoles; Injections, Intraperitoneal; Liver; Male; Oxindoles; Portacaval Shunt, Surgical; Rats; Rats, Sprague-Dawley; Tryptophan

1999
A quantitative evaluation of the permeability of the blood brain barrier of portacaval shunted rats.
    Metabolic brain disease, 2000, Volume: 15, Issue:2

    Topics: Acetates; Animals; Blood-Brain Barrier; Brain; Carbon Radioisotopes; Cerebrovascular Circulation; Disease Models, Animal; Glutamic Acid; Hepatic Encephalopathy; Male; Mannitol; Permeability; Phenylalanine; Portacaval Shunt, Surgical; Rats; Rats, Sprague-Dawley; Tritium

2000
Dialysis in hepatic coma.
    Lancet (London, England), 1976, Oct-23, Volume: 2, Issue:7991

    Topics: Acetates; Hepatic Encephalopathy; Humans; Renal Dialysis

1976
[Acute liver damage due to thioacetamide. Morphology, biochemistry and neurophysiologic comparison with cerebrotoxic substances].
    Fortschritte der Medizin, 1977, Feb-03, Volume: 95, Issue:5

    Topics: Acetamides; Acetates; Acute Disease; Animals; Brain; Brain Diseases; Cats; Chemical and Drug Induced Liver Injury; Electroencephalography; Hepatic Encephalopathy; Phenylacetates; Quaternary Ammonium Compounds; Thioacetamide

1977
[Clinical picture and therapy of portal-systemic encephalopathy (author's transl)].
    Leber, Magen, Darm, 1977, Volume: 7, Issue:4

    Topics: Acetates; Acidosis; Alcoholism; Amino Acids; Ammonia; Astrocytes; Dietary Proteins; Diuretics; Hemorrhage; Hepatic Encephalopathy; Humans; Hypokalemia; Lactulose; Liver; Liver Cirrhosis; Neomycin; Potassium; Skin Manifestations; Water-Electrolyte Balance

1977
Decreased potassium-stimulated release of [3H]D-aspartate from hippocampal slices distinguishes encephalopathy related to acute liver failure from that induced by simple hyperammonemia.
    Brain research, 1991, Dec-13, Volume: 567, Issue:1

    Topics: Acetates; Animals; Aspartic Acid; Female; Hepatic Encephalopathy; Hippocampus; In Vitro Techniques; Kinetics; Potassium; Radioisotope Dilution Technique; Rats; Rats, Inbred Strains; Thioacetamide; Tritium

1991
Content of quinolinic acid and of other tryptophan metabolites increases in brain regions of rats used as experimental models of hepatic encephalopathy.
    Journal of neurochemistry, 1986, Volume: 46, Issue:3

    Topics: Acetates; Animals; Brain; Brain Stem; Cerebellum; Cerebral Cortex; Disease Models, Animal; Hepatic Encephalopathy; Hydroxyindoleacetic Acid; Male; Portacaval Shunt, Surgical; Probenecid; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Serotonin; Tryptophan

1986
Continuous intravenous ammonia infusion as a model for the study of hepatic encephalopathy in rabbits.
    The Journal of surgical research, 1989, Volume: 46, Issue:3

    Topics: Acetates; Acetic Acid; Ammonia; Animals; Blood Glucose; Disease Models, Animal; Electroencephalography; Female; Hepatic Artery; Hepatic Encephalopathy; Hydrogen-Ion Concentration; Infusions, Intravenous; Ligation; Portacaval Shunt, Surgical; Rabbits; Time Factors

1989
Cerebral glucose metabolism after portacaval shunting in the rat. Patterns of metabolism and implications for the pathogenesis of hepatic encephalopathy.
    The Journal of clinical investigation, 1986, Volume: 78, Issue:1

    Topics: Acetates; Ammonia; Animals; Brain; Electroencephalography; Glucose; Hepatic Encephalopathy; Male; Portacaval Shunt, Surgical; Rats; Rats, Inbred Strains

1986
Disruption of the blood-brain barrier in hyperammonemic coma and the pharmacologic effects of dexamethasone and difluoromethyl ornithine.
    Journal of neuroscience research, 1985, Volume: 14, Issue:2

    Topics: Acetates; Ammonia; Animals; Blood-Brain Barrier; Coma; Dexamethasone; Eflornithine; Exploratory Behavior; Female; Grooming; Hepatic Encephalopathy; Mice; Mice, Inbred Strains; Ornithine

1985
Cerebral acetylcholine and energy metabolism changes in acute ammonia intoxication in the lower primate Tupaia glis.
    The Journal of laboratory and clinical medicine, 1985, Volume: 106, Issue:2

    Topics: Acetates; Acetylcholine; Ammonia; Animals; Brain; Brain Stem; Coma; Energy Metabolism; Female; Hepatic Encephalopathy; Tupaia

1985
[Toxic metabolites in the brain of patients with liver cirrhosis and portocaval shunt].
    Deutsche medizinische Wochenschrift (1946), 1973, Oct-12, Volume: 98, Issue:41

    Topics: Acetates; Brain; Brain Chemistry; Brain Edema; Chromatography, Gas; Chromatography, Thin Layer; Esters; Ethers; Hepatic Encephalopathy; Humans; Lactates; Liver Cirrhosis; Portacaval Shunt, Surgical

1973