phenyl acetate has been researched along with Alzheimer Disease in 56 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.79) | 18.7374 |
| 1990's | 4 (7.14) | 18.2507 |
| 2000's | 16 (28.57) | 29.6817 |
| 2010's | 26 (46.43) | 24.3611 |
| 2020's | 9 (16.07) | 2.80 |
| Authors | Studies |
|---|---|
| Datusalia, AK; Gaun, S; Manik, M; Singh, G; Singh, RK; Yadav, N | 1 |
| Choi, JH; Choi, YS; Choi, YW; Ho, MJ; Joung, MY; Kang, MJ; Kim, MS; Lee, S; Park, HJ; Park, JS; Seo, JH; Song, WH | 1 |
| Chen, S; Du, J; Gao, C; He, G; He, Y; Huang, P; Li, B; Tang, H; Zhang, P | 1 |
| Dietlein, M; Dillen, K; Dronse, J; Fink, GR; Jacobs, HIL; Kracht, L; Kukolja, J; Langen, KJ; Nellessen, N; Neumaier, B; Onur, OA; Richter, N | 1 |
| Ai, L; Bai, S; Cai, X; Di, Y; Fei, X; He, R; Lyu, J; Tong, Z; Yao, D; Yu, Y; Zhao, S | 1 |
| Chen, W; Gong, T; Kong, Y; Li, H; Liu, J; Mao, S; Sun, J; Yu, J | 1 |
| Cheng, Y; Hu, S; Li, H; Liu, J; Long, J; Peng, Y; Qin, C; Shi, L; Wang, C; Wang, Y; Xu, X; Zhang, S; Zhao, D | 1 |
| Aigner, L; Hutter-Paier, B; Michael, J; Paiement, N; Poupardin, R; Reitsamer, H; Rieß, T; Unger, MS; Zerbe, H; Zirknitzer, J | 1 |
| Caba, IC; Ştefănescu, R; Tamba, BI | 1 |
| Bertolini, A; Bucciantini, M; Leri, M; Stefani, M | 1 |
| Andreozzi, EM; Blower, PJ; Dunn, J; Sunassee, K; Szanda, I; Torres, JB; Walker-Samuel, S | 1 |
| Baek, SJ; Heo, S; Jung, J; Kim, BC; Kim, DH; Kwon, H; Lee, S; Lee, YC; Park, HJ; Park, SJ; Ryu, JH; Yi, JH | 1 |
| Beckers, N; Dietlein, M; Fink, GR; Kracht, L; Kukolja, J; Neumaier, B; Onur, OA; Richter, N; Tittgemeyer, M | 1 |
| Fukushi, K; Higuchi, M; Hirano, S; Irie, T; Kuwabara, S; Ota, T; Sato, K; Shimada, H; Shinotoh, H; Suhara, T; Tanaka, N; Zhang, MR | 1 |
| Avila, J; Cordero, JG; García-Escudero, R; García-Escudero, V; Gargini, R | 1 |
| Bocti, C; Castellano, CA; Croteau, E; Cunnane, SC; Duchesne, S; Fortier, M; Fülöp, T; Lepage, M; Nugent, S; Richard, MA; Turcotte, ÉE; Whittingstall, K | 1 |
| Jiang, B; Kong, Y; Luo, X | 1 |
| Cho, M; Lee, Y; Qin, J | 1 |
| Abbasov, ME; Alfonso, A; Alonso, E; Alvariño, R; Botana, LM; Chaheine, CM; Conner, ML; Romo, D | 1 |
| Garcia, R; Hu, Z; Li, Q; Olariu, A; Pei, J; Saydoff, JA; Sheng, J; Sun, GY; von Borstel, R | 1 |
| Cappa, SF; Florea, I; Garibotto, V; Marcone, A; Moresco, R; Panzacchi, A; Perani, D; Rinne, J; Tettamanti, M; Virta, JR | 1 |
| Anumala, UR; Czech, C; Goetschy-Meyer, V; Gu, J; Herms, J; Heyny-von Haußen, R; Hilger, I; Hölzer, J; Kramer, T; Lo Monte, F; Mall, G; Schmidt, B; Schön, C | 1 |
| Akashiba, H; Asai, M; Ishikawa, N; Matsuoka, N; Mitani, Y; Ni, K; Nozawa, T; Okabe, M; Saita, K; Shitaka, Y; Uchino, H; Yamasaki, S; Yarimizu, J | 1 |
| Dadashpour, S; Emami, S; Irannejad, H; Ozadali, K; Tuylu Kucukkilinc, T; Unsal Tan, O | 1 |
| Aderibigbe, AO; Adewole, FA; Ajayi, AM; Eduviere, AT; Umukoro, S | 1 |
| Bowen, ZD; Bryleva, EY; Chang, CCY; Chang, TY; Harris, BT; Kheirollah, A; Murphy, SR; Niu, Z; Shibuya, Y | 1 |
| McGilvray, A | 1 |
| Brown, RE; Roberts, AD; Roddick, KM; Schellinck, HM | 1 |
| Chen, CL; Chen, PT; Chen, RP; Hu, CJ; Lin, LT; Lo, CH; Wang, SS | 1 |
| Huang, SW; Liu, QB; Luo, SY; Peng, Y; Song, SJ; Sun, B; Wang, W; Wu, DL; Zhang, MY | 1 |
| Dietlein, M; Fink, GR; Kracht, L; Kukolja, J; Michel, A; Neumaier, B; Onur, OA; Richter, N; Tittgemeyer, M | 1 |
| Gibbs, ME; Gibbs, Z; Hertz, L | 1 |
| Barren, C; Duller, S; Frosch, MP; Havas, D; Hutter-Paier, B; Huttunen, HJ; Kovacs, DM; Peach, C; Windisch, M; Xia, W | 1 |
| Brorsson, AC; Göransson, AL; Kågedal, K; Nilsson, KP | 1 |
| Choi, SJ; Heo, HJ; Jeong, HR; Jeong, JH; Jin, DE; Jo, YN; Shin, DH; Song, BG | 1 |
| Akashiba, H; Matsuoka, N; Mitani, Y; Ni, K; Shitaka, Y; Yarimizu, J | 1 |
| Järvenpää, T; Kaasinen, V; Kurki, T; Någren, K; Oikonen, V; Rinne, JO; Roivainen, A; Yu, M | 1 |
| Koudinov, AR; Koudinova, NV | 1 |
| Bauer, B; Heiss, WD; Herholz, K; Kalbe, E; Lenz, O; Schröder, H; Weisenbach, S; Zündorf, G | 1 |
| Alkhalil, B; Alkhalil, C; Hahar, N; Lowenthal, DT; Zavros, G | 1 |
| Mascalzi, MG; Raudino, F; Zagami, A | 1 |
| Aotsuka, A; Arai, H; Fukushi, K; Irie, T; Iyo, M; Nagatsuka, S; Namba, H; Ota, T; Sato, K; Shinotoh, H; Shiraishi, T; Tanada, S; Tanaka, N | 1 |
| Baumann, K; Haass, C; Narlawar, R; Pérez Revuelta, BI; Schmidt, B; Schubenel, R; Steiner, H | 1 |
| Ge, H; Lin, C; Ma, L; Peng, W; Song, H; Wang, Z; Wen, H; Zhou, Y | 1 |
| Atanassov, CL; Knödgen, B; Muller, CD; Rebel, G; Sarhan, S; Seiler, N | 1 |
| Fukushi, K; Ikota, N; Irie, T; Iyo, M; Nagatsuka, S; Namba, H; Tamagami, H | 1 |
| Gordon, SM; Regan, WM | 1 |
| Ancill, RJ; Holliday, SG; Sheldon, LJ | 1 |
| Feinberg, TE; Meckler, L; Miner, CR; Roane, DM; Rosenthal, RN; Scicutella, A | 1 |
| Buffa, C; Dallocchio, C; Mazzarello, P | 1 |
| Aotsuka, A; Fukushi, K; Irie, T; Iyo, M; Nagatsuka , S; Namba, H; Ota, T; Shinotoh, H; Tanada, S; Tanaka, N | 1 |
| Bauer, B; Heiss, WD; Herholz, K; Lenz, O; Lercher, M; Wienhard, K | 1 |
| Bauer, B; Heiss, WD; Herholz, K; Kracht, L; Lenz, MO; Mielke, R; Strotmann, T; Wienhard, K | 1 |
| Antonello, RM; Cazzato, G; Moretti, R; Torre, P | 1 |
| Aotsuka, A; Fukushi, K; Irie, T; Iyo, M; Nagatsuka Si, S; Namba, H; Ota, T; Shinotoh, H; Tanada, S; Tanaka, N | 1 |
| Blair, JA; Cowburn, JD | 1 |
2 review(s) available for phenyl acetate and Alzheimer Disease
| Article | Year |
|---|---|
Targeted Delivery of Montelukast for the Treatment of Alzheimer's Disease.
Topics: Acetates; Alzheimer Disease; Cyclopropanes; Humans; Leukotrienes; Quinolines; Sulfides | 2022 |
Benefit of Oleuropein Aglycone for Alzheimer's Disease by Promoting Autophagy.
Topics: Acetates; Alzheimer Disease; Animals; Autophagy; Cyclopentane Monoterpenes; Humans; Pyrans; TOR Serine-Threonine Kinases | 2018 |
5 trial(s) available for phenyl acetate and Alzheimer Disease
| Article | Year |
|---|---|
Brain acetylcholinesterase activity in mild cognitive impairment and early Alzheimer's disease.
Topics: Acetates; Acetylcholinesterase; Aged; Alzheimer Disease; Analysis of Variance; Brain; Carbon Radioisotopes; Cognition Disorders; Female; Hippocampus; Humans; Imaging, Three-Dimensional; Male; Middle Aged; Neuropsychological Tests; Piperidines; Predictive Value of Tests; Reference Values; Tomography, Emission-Computed | 2003 |
A simple method for the detection of abnormal brain regions in Alzheimer's disease patients using [11C]MP4A: comparison with [123I]IMP SPECT.
Topics: Acetates; Acetylcholinesterase; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Carbon Radioisotopes; Cerebral Cortex; Female; Humans; Image Interpretation, Computer-Assisted; Iofetamine; Male; Middle Aged; Piperidines; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2004 |
Positron emission tomographic measurement of brain acetylcholinesterase activity using N-[(11)C]methylpiperidin-4-yl acetate without arterial blood sampling: methodology of shape analysis and its diagnostic power for Alzheimer's disease.
Topics: Acetates; Acetylcholinesterase; Aged; Alzheimer Disease; Arteries; Blood Specimen Collection; Brain; Carbon Radioisotopes; Humans; Middle Aged; Monte Carlo Method; Piperidines; Tomography, Emission-Computed | 2001 |
Gabapentin as a possible treatment of behavioral alterations in Alzheimer disease (AD) patients.
Topics: Acetates; Aged; Alzheimer Disease; Amines; Behavior; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Agonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male | 2001 |
Kinetic analysis of [(11)C]MP4A using a high-radioactivity brain region that represents an integrated input function for measurement of cerebral acetylcholinesterase activity without arterial blood sampling.
Topics: Acetates; Acetylcholinesterase; Adult; Aged; Alzheimer Disease; Blood Specimen Collection; Brain; Carbon Radioisotopes; Computer Simulation; Humans; Kinetics; Least-Squares Analysis; Middle Aged; Models, Biological; Piperidines; Tomography, Emission-Computed | 2001 |
49 other study(ies) available for phenyl acetate and Alzheimer Disease
| Article | Year |
|---|---|
Design of Montelukast Nanocrystalline Suspension for Parenteral Prolonged Delivery.
Topics: Acetates; Alzheimer Disease; Animals; Cyclopropanes; Nanoparticles; Particle Size; Quinolines; Rats; Solubility; Sulfides; Suspensions | 2022 |
Early changes of fecal short-chain fatty acid levels in patients with mild cognitive impairments.
Topics: Acetates; Alzheimer Disease; Amyloid beta-Peptides; Atrophy; Butyric Acid; Caproates; Cognitive Dysfunction; Fatty Acids, Volatile; Humans; Positron-Emission Tomography | 2023 |
Spatial distributions of cholinergic impairment and neuronal hypometabolism differ in MCI due to AD.
Topics: Acetates; Acetylcholinesterase; Aged; Aged, 80 and over; Alzheimer Disease; Cognitive Dysfunction; Female; Fluorodeoxyglucose F18; Humans; Male; Middle Aged; Piperidines; Positron-Emission Tomography; Radiopharmaceuticals | 2019 |
A rapid and non-invasive fluorescence method for quantifying coenzyme Q10 in blood and urine in clinical analysis.
Topics: Acetates; Aged; Alzheimer Disease; Chemistry, Clinical; Chromatography, High Pressure Liquid; Fluorescence; Humans; Limit of Detection; Spectrometry, Fluorescence; Temperature; Time Factors; Ubiquinone | 2020 |
Anti-neuroinflammatory Effect of Short-Chain Fatty Acid Acetate against Alzheimer's Disease via Upregulating GPR41 and Inhibiting ERK/JNK/NF-κB.
Topics: Acetates; Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents; Cognition; Cyclooxygenase 2; Extracellular Signal-Regulated MAP Kinases; Fatty Acids, Volatile; Humans; Male; MAP Kinase Kinase 4; Mice; Mice, Transgenic; Neuroprotective Agents; NF-kappa B; Receptors, G-Protein-Coupled; Up-Regulation | 2020 |
Hydroxytyrosol Acetate Improves the Cognitive Function of APP/PS1 Transgenic Mice in ERβ-dependent Manner.
Topics: Acetates; Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Catechols; Cognition; Disease Models, Animal; Encephalitis; Estrogen Receptor beta; Female; Hippocampus; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Neuroprotective Agents; Presenilin-1; Rats, Wistar | 2021 |
The Leukotriene Receptor Antagonist Montelukast Attenuates Neuroinflammation and Affects Cognition in Transgenic 5xFAD Mice.
Topics: Acetates; Alzheimer Disease; Animals; Brain; CD8-Positive T-Lymphocytes; Cognition; Cyclopropanes; Inflammation; Leukotriene Antagonists; Mice; Mice, Transgenic; Quinolines; Sulfides | 2021 |
Observation of Intact and Proteolytically Cleaved Amyloid-Beta (1-40)-Oleuropein Noncovalent Complex at Neutral pH by Mass Spectrometry.
Topics: Acetates; Alzheimer Disease; Amyloid beta-Peptides; Bicarbonates; Binding Sites; Humans; Hydrogen-Ion Concentration; Iridoid Glucosides; Mass Spectrometry; Peptide Fragments; Peptide Hydrolases; Protein Binding; Proteolysis; Solvents; Spectrometry, Mass, Electrospray Ionization; Trypsin | 2021 |
EVOO Polyphenols Relieve Synergistically Autophagy Dysregulation in a Cellular Model of Alzheimer's Disease.
Topics: Acetates; Alzheimer Disease; Amyloid beta-Peptides; Autophagy; Cell Line; Cyclopentane Monoterpenes; Diet, Mediterranean; Humans; Mitochondria; Models, Neurological; Nerve Degeneration; Neurons; Olive Oil; Peptide Fragments; Phenylethyl Alcohol; Polyphenols; Proteasome Endopeptidase Complex; Pyrans; Reactive Oxygen Species; Ubiquitin | 2021 |
Studies of copper trafficking in a mouse model of Alzheimer's disease by positron emission tomography: comparison of
Topics: Acetates; Administration, Intravenous; Alzheimer Disease; Animals; Biological Transport; Brain; Coordination Complexes; Copper Radioisotopes; Disease Models, Animal; Humans; Metabolic Clearance Rate; Mice, Transgenic; Organometallic Compounds; Positron-Emission Tomography; Thiosemicarbazones; Tissue Distribution | 2017 |
Direct pharmacological Akt activation rescues Alzheimer's disease like memory impairments and aberrant synaptic plasticity.
Topics: Acetates; Alzheimer Disease; Amyloid beta-Peptides; Animals; Avoidance Learning; Benzofurans; Benzopyrans; Disease Models, Animal; Enzyme Inhibitors; Evoked Potentials; Gene Expression Regulation; Hippocampus; Male; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuronal Plasticity; Oligopeptides; Oncogene Protein v-akt; Oxadiazoles; Peptide Fragments; Reaction Time; Recognition, Psychology | 2018 |
Effect of cholinergic treatment depends on cholinergic integrity in early Alzheimer's disease.
Topics: Acetates; Acetylcholinesterase; Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Cerebral Cortex; Cholinergic Agents; Cognitive Dysfunction; Female; Humans; Magnetic Resonance Imaging; Male; Mental Status Schedule; Middle Aged; Neuropsychological Tests; Oxygen; Piperidines; Positron-Emission Tomography; Rivastigmine | 2018 |
Voxel-Based Acetylcholinesterase PET Study in Early and Late Onset Alzheimer's Disease.
Topics: Acetates; Acetylcholinesterase; Age of Onset; Aged; Aging; Alzheimer Disease; Brain; Brain Mapping; Carbon Radioisotopes; Female; Humans; Male; Middle Aged; Piperidines; Positron-Emission Tomography; Radiopharmaceuticals | 2018 |
Ketogenic Medium Chain Triglycerides Increase Brain Energy Metabolism in Alzheimer's Disease.
Topics: Acetates; Aged; Aged, 80 and over; Alzheimer Disease; Brain; Carbon; Energy Metabolism; Female; Fluorodeoxyglucose F18; Humans; Ketones; Magnetic Resonance Imaging; Male; Positron-Emission Tomography; Triglycerides | 2018 |
Gut microbiota influences Alzheimer's disease pathogenesis by regulating acetate in Drosophila model.
Topics: Acetates; Alzheimer Disease; Animals; Bacteria; Biodiversity; Disease Models, Animal; Drosophila; Gastrointestinal Microbiome; Metabolome; Phenotype; RNA, Ribosomal, 16S | 2018 |
Ultrasensitive Detection of Amyloid-β Using Cellular Prion Protein on the Highly Conductive Au Nanoparticles-Poly(3,4-ethylene dioxythiophene)-Poly(thiophene-3-acetic acid) Composite Electrode.
Topics: Acetates; Alzheimer Disease; Amyloid beta-Peptides; Animals; Biosensing Techniques; Bridged Bicyclo Compounds, Heterocyclic; Electric Conductivity; Electrochemical Techniques; Electrodes; Gold; Metal Nanoparticles; Mice; Polymers; Prion Proteins; Thiophenes | 2019 |
Gracilin A Derivatives Target Early Events in Alzheimer's Disease: in Vitro Effects on Neuroinflammation and Oxidative Stress.
Topics: Acetates; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Cytokines; Diterpenes; Furans; Humans; Inflammation; Lipopolysaccharides; Microglia; Neuroprotection; Neuroprotective Agents; Oxidative Stress | 2019 |
Uridine prodrug improves memory in Tg2576 and TAPP mice and reduces pathological factors associated with Alzheimer's disease in related models.
Topics: Acetates; Alzheimer Disease; Animals; Cell Line, Tumor; Cricetinae; Disease Models, Animal; Female; Gerbillinae; Humans; Male; Maze Learning; Memory; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Prodrugs; Stroke; Uridine | 2013 |
Cholinergic activity correlates with reserve proxies in Alzheimer's disease.
Topics: Acetates; Acetylcholine; Aged; Aged, 80 and over; Alzheimer Disease; Carbon Isotopes; Cognitive Dysfunction; Cognitive Reserve; Educational Status; Employment; Female; Fluorodeoxyglucose F18; Humans; Male; Mental Status Schedule; Middle Aged; Piperidines; Positron-Emission Tomography; Radiography; Statistics, Nonparametric; Tomography Scanners, X-Ray Computed | 2013 |
Fluorescent rhodanine-3-acetic acids visualize neurofibrillary tangles in Alzheimer's disease brains.
Topics: Acetates; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cell Line, Tumor; Cell Survival; Embryo, Nonmammalian; Fluorescent Dyes; Humans; Microscopy, Fluorescence; Peptide Fragments; Rhodanine; tau Proteins; Zebrafish | 2013 |
Pharmacological characterization of the novel γ-secretase modulator AS2715348, a potential therapy for Alzheimer's disease, in rodents and nonhuman primates.
Topics: Acetates; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Brain; Cell Line, Tumor; Cognition; Cyclohexylamines; Disease Models, Animal; Female; Humans; Macaca fascicularis; Male; Mice; Mice, Transgenic; Molecular Structure; Neuroprotective Agents; Nootropic Agents; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Notch | 2014 |
Design, synthesis and in vitro study of 5,6-diaryl-1,2,4-triazine-3-ylthioacetate derivatives as COX-2 and β-amyloid aggregation inhibitors.
Topics: Acetates; Alzheimer Disease; Amyloid beta-Peptides; Blood-Brain Barrier; Cyclooxygenase 2 Inhibitors; Drug Design; Molecular Docking Simulation; Molecular Structure; Permeability; Plaque, Amyloid; Protein Aggregation, Pathological; Protein Stability; Structure-Activity Relationship; Triazines | 2015 |
Methyl jasmonate enhances memory performance through inhibition of oxidative stress and acetylcholinesterase activity in mice.
Topics: Acetates; Alzheimer Disease; Analysis of Variance; Animals; Biomarkers; Brain; Catalase; Cholinesterase Inhibitors; Cyclopentanes; Male; Malondialdehyde; Maze Learning; Memory; Mice; Oxidative Stress; Oxylipins; Recognition, Psychology; Scopolamine; Superoxide Dismutase | 2015 |
Acyl-coenzyme A:cholesterol acyltransferase 1 blockage enhances autophagy in the neurons of triple transgenic Alzheimer's disease mouse and reduces human P301L-tau content at the presymptomatic stage.
Topics: Acetamides; Acetates; Acetyl-CoA C-Acetyltransferase; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Autophagy; Benzimidazoles; Brain; Cells, Cultured; Cholesterol; Cholesterol Esters; Disease Models, Animal; Enzyme Inhibitors; Gene Knockdown Techniques; Mice, Inbred C57BL; Mice, Transgenic; Molecular Targeted Therapy; Neurons; Peptide Fragments; Presenilin-1; Sulfonamides; Sulfonic Acids; tau Proteins | 2015 |
Ageing: Restoration project.
Topics: Acetates; Aging; Alzheimer Disease; Animals; Anti-Asthmatic Agents; Cognition Disorders; Cyclopropanes; Estrogens; Female; Hippocampus; Humans; Inflammation Mediators; Leukotrienes; Macaca mulatta; Male; Mice; Neuronal Plasticity; Parkinson Disease; Plasma; Prefrontal Cortex; Quinolines; Rats; Rejuvenation; Sulfides; Synapses | 2016 |
Sex and Genotype Differences in Odor Detection in the 3×Tg-AD and 5XFAD Mouse Models of Alzheimer's Disease at 6 Months of Age.
Topics: Acetates; Alzheimer Disease; Animals; Behavior, Animal; Discriminant Analysis; Disease Models, Animal; Female; Genotype; Male; Mice; Mice, Transgenic; Sex Factors; Smell | 2016 |
Design of Peptide Substrate for Sensitively and Specifically Detecting Two Aβ-Degrading Enzymes: Neprilysin and Angiotensin-Converting Enzyme.
Topics: Acetates; Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Cell Line, Tumor; Chromones; Humans; Insulysin; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Proteolysis; Spectrometry, Fluorescence; Substrate Specificity | 2016 |
The effect of ethyl acetate extract from persimmon leaves on Alzheimer's disease and its underlying mechanism.
Topics: Acetates; Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Diospyros; Glutathione Peroxidase; Hippocampus; Male; Malondialdehyde; MAP Kinase Signaling System; Maze Learning; Microinjections; Peptide Fragments; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley; Solvents; Superoxide Dismutase | 2016 |
White matter lesions and the cholinergic deficit in aging and mild cognitive impairment.
Topics: Acetates; Acetylcholinesterase; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Cognitive Dysfunction; Female; Humans; Male; Memory; Middle Aged; Neuropsychological Tests; Piperidines; Positron-Emission Tomography; White Matter | 2017 |
Rescue of Abeta(1-42)-induced memory impairment in day-old chick by facilitation of astrocytic oxidative metabolism: implications for Alzheimer's disease.
Topics: 3-Hydroxybutyric Acid; Acetates; Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Newborn; Astrocytes; Caprylates; Chickens; Citric Acid Cycle; Discrimination Learning; Glucose; Hypoglycemic Agents; Insulin; Ketone Bodies; Lactic Acid; Memory Disorders; Oxidation-Reduction; Peptide Fragments; Reinforcement, Psychology | 2009 |
The acyl-coenzyme A: cholesterol acyltransferase inhibitor CI-1011 reverses diffuse brain amyloid pathology in aged amyloid precursor protein transgenic mice.
Topics: Acetamides; Acetates; Aging; Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Apolipoproteins E; Brain; Cholesterol; Disease Models, Animal; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Gliosis; Humans; Image Processing, Computer-Assisted; Liver; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Peptide Fragments; Presenilin-1; Pyridines; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids | 2010 |
Identification of distinct physiochemical properties of toxic prefibrillar species formed by Aβ peptide variants.
Topics: Acetates; Alzheimer Disease; Amyloid beta-Peptides; Anilino Naphthalenesulfonates; Cell Line; Fluorescent Dyes; Humans; Microscopy, Electron, Transmission; Peptide Fragments; Thiophenes | 2012 |
Antiamnesic effects of ethyl acetate fraction from chestnut (Castanea crenata var. dulcis) inner skin on Aβ(25-35)-induced cognitive deficits in mice.
Topics: Acetates; Alzheimer Disease; Amyloid beta-Peptides; Animals; Catechin; Cell Survival; Chromatography, High Pressure Liquid; Cognition Disorders; Fagaceae; Fluoresceins; Gallic Acid; Hydrogen Peroxide; L-Lactate Dehydrogenase; Learning; Male; Memory; Mice; Mice, Inbred ICR; Neurons; Oxidative Stress; PC12 Cells; Plant Extracts; Rats; Reactive Oxygen Species | 2012 |
Amelioration of cognitive deficits in plaque-bearing Alzheimer's disease model mice through selective reduction of nascent soluble Aβ42 without affecting other Aβ pools.
Topics: Acetates; Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Antibodies; Chromatography, Liquid; Cognition Disorders; Disease Models, Animal; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Hippocampus; Humans; Mass Spectrometry; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Peptide Fragments; Piperidines | 2013 |
Cholesterol, synaptic function and Alzheimer's disease.
Topics: Acetates; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cholesterol; Disease Models, Animal; Electric Stimulation; Humans; Immunohistochemistry; In Vitro Techniques; Learning Disabilities; Long-Term Potentiation; Memory Disorders; Nerve Degeneration; Neurodegenerative Diseases; Rats; Rats, Wistar; Risk Factors; Synapses; Synaptic Transmission; Tritium | 2003 |
In vivo study of acetylcholine esterase in basal forebrain, amygdala, and cortex in mild to moderate Alzheimer disease.
Topics: Acetates; Acetylcholinesterase; Aged; Alzheimer Disease; Amygdala; Basal Nucleus of Meynert; Blood Glucose; Carbon Radioisotopes; Cerebral Cortex; Cholinergic Fibers; Female; Fluorodeoxyglucose F18; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Piperidines; Tomography, Emission-Computed | 2004 |
Can gabapentin be a safe alternative to hormonal therapy in the treatment of inappropriate sexual behavior in demented patients?
Topics: Acetates; Aged; Alzheimer Disease; Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hormones; Humans; Male; Sexual Behavior; Sexual Dysfunctions, Psychological | 2003 |
Gabapentin and behavioral disorders in severe Alzheimer disease.
Topics: Acetates; Aged; Aged, 80 and over; Alzheimer Disease; Amines; Cyclohexanecarboxylic Acids; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male | 2004 |
N-Substituted carbazolyloxyacetic acids modulate Alzheimer associated gamma-secretase.
Topics: Acetates; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Humans | 2007 |
Methyl 2-(2-(4-formylphenoxy)acetamido)-2-substituted acetate derivatives: a new class of acetylcholinesterase inhibitors.
Topics: Acetates; Alzheimer Disease; Benzaldehydes; Cholinesterase Inhibitors; Humans; Inhibitory Concentration 50; Structure-Activity Relationship | 2007 |
Effect of ammonia on endocytosis, cytokine production and lysosomal enzyme activity of a microglial cell line.
Topics: Acetates; Acid Phosphatase; Alzheimer Disease; Ammonia; Animals; beta-Glucosidase; Cathepsin D; Cell Line; Cytokines; Endocytosis; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Interleukin-1; Interleukin-6; Lysosomes; Mice; Microglia; Phagocytosis; Tumor Necrosis Factor-alpha | 1994 |
Brain acetylcholinesterase activity: validation of a PET tracer in a rat model of Alzheimer's disease.
Topics: Acetates; Acetylcholinesterase; Alzheimer Disease; Amphetamines; Animals; Brain; Carbon Radioisotopes; Iodine Radioisotopes; Iofetamine; Male; Piperidines; Propionates; Rats; Rats, Wistar; Sensitivity and Specificity; Tomography, Emission-Computed | 1996 |
Gabapentin for behavioral agitation in Alzheimer's disease.
Topics: Acetates; Aged; Alzheimer Disease; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Haloperidol; Humans; Psychomotor Agitation; Treatment Outcome | 1997 |
Gabapentin in geriatric psychiatry patients.
Topics: Acetates; Aged; Aged, 80 and over; Alzheimer Disease; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Dementia; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male | 1998 |
Treatment of dementia-associated agitation with gabapentin.
Topics: Acetates; Aged; Aged, 80 and over; Alzheimer Disease; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dementia, Multi-Infarct; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Mental Status Schedule; Neurologic Examination; Psychomotor Agitation | 2000 |
Combination of donepezil and gabapentin for behavioral disorders in Alzheimer's disease.
Topics: Acetates; Aged; Aged, 80 and over; Alzheimer Disease; Amines; Anticonvulsants; Cholinesterase Inhibitors; Cyclohexanecarboxylic Acids; Donepezil; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Indans; Male; Mental Disorders; Piperidines; Psychiatric Status Rating Scales; Treatment Outcome | 2000 |
PET measurement of cerebral acetylcholine esterase activity without blood sampling.
Topics: Acetates; Acetylcholinesterase; Aged; Algorithms; Alzheimer Disease; Basal Ganglia; Brain; Female; Humans; Lewy Body Disease; Male; Middle Aged; Piperidines; Radiopharmaceuticals; Tomography, Emission-Computed | 2001 |
In-vivo measurements of regional acetylcholine esterase activity in degenerative dementia: comparison with blood flow and glucose metabolism.
Topics: Acetates; Acetylcholinesterase; Aged; Alzheimer Disease; Brain; Brain Stem; Carbon Radioisotopes; Cerebellum; Cerebrovascular Circulation; Corpus Striatum; Female; Glucose; Humans; Lewy Body Disease; Male; Mental Status Schedule; Middle Aged; Piperidines; Reference Values; Regression Analysis; Thalamus; Tomography, Emission-Computed | 2000 |
Aluminium chelator (transferrin) reverses biochemical deficiency in Alzheimer brain preparations.
Topics: Acetates; Alzheimer Disease; Biopterins; Brain; Chelating Agents; Humans; Transferrin | 1989 |