phenyl acetate has been researched along with ACY2 Deficiency in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anikster, Y; Arun, P; Gahl, WA; Grunberg, NE; Madhavarao, CN; Moffett, JR; Mog, SR; Namboodiri, AMA; Staretz-Chacham, O | 1 |
| Anikster, Y; Ariyannur, PS; Arun, P; Denu, JM; Gahl, WA; Grunberg, NE; Hallows, WC; Hamilton, K; Madhavarao, CN; Moffett, JR; Mog, S; Namboodiri, AM | 1 |
| Baslow, MH; Guilfoyle, DN | 1 |
| Chen, V | 1 |
| Arun, P; Madhavarao, CN; Mathew, R; Moffett, JR; Namboodiri, MA | 1 |
| Arun, P; Hershfield, J; Jacobowitz, DM; Kirmani, B; Madhavarao, CN; Mathew, R; Moffett, JR; Namboodiri, AM; Namboodiri, S; Potti, A | 1 |
| During, MJ; Janson, CG; Leone, P; McPhee, SJ | 1 |
2 review(s) available for phenyl acetate and ACY2 Deficiency
| Article | Year |
|---|---|
Defective myelin lipid synthesis as a pathogenic mechanism of Canavan disease.
Topics: Acetates; Acetyltransferases; Amidohydrolases; Animals; Aspartic Acid; Canavan Disease; Humans; Lipid Metabolism; Myelin Sheath | 2006 |
Global CNS gene transfer for a childhood neurogenetic enzyme deficiency: Canavan disease.
Topics: Acetates; Acetazolamide; Amidohydrolases; Animals; Aspartic Acid; Brain; Brain Edema; Calcium Compounds; Canavan Disease; Child; Child, Preschool; Cholesterol; Combined Modality Therapy; Cytomegalovirus; Dependovirus; DNA, Recombinant; Female; Fetal Diseases; Genetic Therapy; Genetic Vectors; Glycerophospholipids; Humans; Infant; Injections, Intraventricular; Liposomes; Male; Mitochondria; Nerve Tissue Proteins; Osmotic Pressure; Phosphatidylethanolamines; Prenatal Diagnosis; Primates; Promoter Regions, Genetic; Protamines; Rats | 1999 |
1 trial(s) available for phenyl acetate and ACY2 Deficiency
| Article | Year |
|---|---|
Glyceryl triacetate for Canavan disease: a low-dose trial in infants and evaluation of a higher dose for toxicity in the tremor rat model.
Topics: Acetates; Administration, Oral; Animals; Animals, Newborn; Canavan Disease; Dietary Supplements; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Humans; Infant; Male; Rats; Rats, Inbred WKY; Tremor; Triacetin; Triglycerides | 2009 |
4 other study(ies) available for phenyl acetate and ACY2 Deficiency
| Article | Year |
|---|---|
Metabolic acetate therapy improves phenotype in the tremor rat model of Canavan disease.
Topics: Acetates; Animals; Aspartic Acid; Brain; Canavan Disease; Disease Models, Animal; Female; Heterozygote; Lipids; Male; Mutation; Myelin Sheath; Phenotype; Rats; Treatment Outcome | 2010 |
Canavan disease, a rare early-onset human spongiform leukodystrophy: insights into its genesis and possible clinical interventions.
Topics: Acetates; Animals; Aspartic Acid; Brain; Canavan Disease; Extracellular Fluid; Humans; Myelin Sheath; Osmosis; Signal Transduction; Water; Water-Electrolyte Balance | 2013 |
Dietary treatment proposed for Canavan's disease.
Topics: Acetates; Amidohydrolases; Animals; Aspartic Acid; Brain; Canavan Disease; Dietary Supplements; Food, Formulated; Humans; Lipids; Mice; Myelin Sheath; Oligodendroglia | 2005 |
Progress toward acetate supplementation therapy for Canavan disease: glyceryl triacetate administration increases acetate, but not N-acetylaspartate, levels in brain.
Topics: Acetates; Animals; Aspartic Acid; Brain; Calcium Compounds; Canavan Disease; Liver; Male; Mice; Mice, Inbred C57BL | 2005 |