phentolamine has been researched along with Urinary Incontinence, Stress in 6 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
Urinary Incontinence, Stress: Involuntary discharge of URINE as a result of physical activities that increase abdominal pressure on the URINARY BLADDER without detrusor contraction or overdistended bladder. The subtypes are classified by the degree of leakage, descent and opening of the bladder neck and URETHRA without bladder contraction, and sphincter deficiency.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To clarify the role of noradrenergic pathways in preventing stress urinary incontinence (SUI) during sneezing, we investigated the effect of the norepinephrine reuptake inhibitor nisoxetine and alpha-adrenoceptor antagonists phentolamine (nonspecific blocker) and prazosin (alpha(1)-receptor-selective blocker) on the neurally evoked urethral continence reflex induced by sneezing in rats." | 3.74 | Role of noradrenergic pathways in sneeze-induced urethral continence reflex in rats. ( Arai, Y; Chancellor, MB; de Groat, WC; Kaiho, Y; Kamo, I; Yoshimura, N, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cannon, TW | 1 |
| Lee, JY | 1 |
| Somogyi, G | 1 |
| Pruchnic, R | 1 |
| Smith, CP | 1 |
| Huard, J | 1 |
| Chancellor, MB | 2 |
| Kaiho, Y | 1 |
| Kamo, I | 1 |
| Arai, Y | 1 |
| de Groat, WC | 1 |
| Yoshimura, N | 1 |
| el Hemaly, AK | 1 |
| Mousa, LA | 1 |
| Andersen, JT | 1 |
| Bradley, WE | 1 |
| Caine, M | 1 |
| Raz, S | 1 |
| McGuire, EJ | 1 |
| Herlihy, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase II Clinical Trial to Study the Feasibility and Safety of the Expanded Autologous Mesenchymal Stem Cells Use Derived From Adipose Tissue (ASC) for the Local Feminine Stress Urinary Incontinence[NCT01804153] | Phase 1/Phase 2 | 10 participants (Anticipated) | Interventional | 2012-09-30 | Recruiting | ||
| Phase II Clinical Trial to Study the Feasibility and Safety of the Expanded Autologous Stem Cells Use Derived From Adipose Tissue (e-ASC) for the Local Urinary Incontinence After a Radical Prostate Cancer Surgery[NCT01799694] | Phase 2 | 10 participants (Actual) | Interventional | 2011-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for phentolamine and Urinary Incontinence, Stress
| Article | Year |
|---|---|
Some clinical implications of adrenergic receptors in the urinary tract.
Topics: Adrenergic Agonists; Adrenergic alpha-Antagonists; Autonomic Agents; Estrogens; Female; Humans; Imip | 1975 |
1 trial available for phentolamine and Urinary Incontinence, Stress
| Article | Year |
|---|---|
Stress urinary incontinence, a new concept.
Topics: Adrenergic alpha-Antagonists; Collagen; Elastic Tissue; Female; Humans; Norepinephrine; Phentolamine | 1996 |
4 other studies available for phentolamine and Urinary Incontinence, Stress
| Article | Year |
|---|---|
Improved sphincter contractility after allogenic muscle-derived progenitor cell injection into the denervated rat urethra.
Topics: Animals; CD4-Positive T-Lymphocytes; Denervation; Electric Stimulation; Female; Lymphocyte Activatio | 2003 |
Improved sphincter contractility after allogenic muscle-derived progenitor cell injection into the denervated rat urethra.
Topics: Animals; CD4-Positive T-Lymphocytes; Denervation; Electric Stimulation; Female; Lymphocyte Activatio | 2003 |
Improved sphincter contractility after allogenic muscle-derived progenitor cell injection into the denervated rat urethra.
Topics: Animals; CD4-Positive T-Lymphocytes; Denervation; Electric Stimulation; Female; Lymphocyte Activatio | 2003 |
Improved sphincter contractility after allogenic muscle-derived progenitor cell injection into the denervated rat urethra.
Topics: Animals; CD4-Positive T-Lymphocytes; Denervation; Electric Stimulation; Female; Lymphocyte Activatio | 2003 |
Role of noradrenergic pathways in sneeze-induced urethral continence reflex in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Female; Fluoxetine; Norepinephr | 2007 |
Urethral pressure profilometry: assessment of urethral function by combined intraurethral pressure and electromyographic recording.
Topics: Carbon Dioxide; Electromyography; Female; Humans; Male; Muscle, Smooth; Phentolamine; Pressure; Pros | 1977 |
The influence of urethral position on urinary continence.
Topics: Abdomen; Animals; Cats; Curare; Female; Male; Phentolamine; Pressure; Spinal Nerve Roots; Urethra; U | 1977 |