Page last updated: 2024-11-06

phentolamine and Stomach Ulcer

phentolamine has been researched along with Stomach Ulcer in 21 studies

Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.

Stomach Ulcer: Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).

Research Excerpts

ExcerptRelevanceReference
" However, the gastroprotective effect of chronic stress was not manifested and there was no aggravation of indomethacin-induced gastric ulceration, either."3.79Does chronic stress enhance the risk of diseases? ( Filaretova, L; Laszlo, F; Morozova, O; Morschl, E; Zelena, D, 2013)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199016 (76.19)18.7374
1990's4 (19.05)18.2507
2000's0 (0.00)29.6817
2010's1 (4.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Filaretova, L1
Morozova, O1
Laszlo, F1
Morschl, E1
Zelena, D1
Mine, K1
Noda, T1
Fujiwara, M1
Tsuruta, N1
Ueki, S1
Nakagawa, T1
Nobrega, JN1
Wiener, NI1
Kagoshima, M1
Suguro, N1
Clementi, G1
Caruso, A1
Cutuli, VM1
de Bernardis, E1
Prato, A1
Mangano, NG1
Amico-Roxas, M1
Xu, XG1
Zhu, JQ1
Lu, Q1
Vila, J1
Esplugues, J1
Orts, A1
Bedate, H1
Morales-Olivas, FJ1
Dai, S1
Ogle, CW1
Kasuya, Y1
Urushidani, T1
Okabe, S5
Menguy, R1
Masters, YF1
Rainsford, KD1
Takeuchi, K2
Takagi, K4
Hidalgo, J1
Gasull, T1
Garcia, A1
Blanquez, A1
Armario, A1
D'Souza, RS1
Bhandare, PN1
Dhume, VG1
Djahanguiri, B3
Saziki, R1
Taubin, HL1
Landsberg, L1
Honda, K1
Bhargava, KP1
Gupta, MB1
Tangri, KK1
Sadeghi, D1
Pousti, A1
Hemmati, S1
Firouzabadi, A1

Other Studies

21 other studies available for phentolamine and Stomach Ulcer

ArticleYear
Does chronic stress enhance the risk of diseases?
    Endocrine regulations, 2013, Volume: 47, Issue:4

    Topics: Adrenergic alpha-Antagonists; Angina Pectoris; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chr

2013
Autonomic drug effects and gastric secretion in a new experimental model of stress ulcers in rats.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:2

    Topics: Animals; Atropine Derivatives; Autonomic Agents; Behavior, Animal; Gastric Juice; Hexamethonium; Hex

1983
Effects of catecholamine agonist and antagonist drugs on acute stomach ulceration induced by medial hypothalamic lesions in rats.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:5

    Topics: Amphetamine; Animals; Catecholamines; Chlorpromazine; Clozapine; Desipramine; Haloperidol; Hypothala

1983
[Gastric movements and reserpine-induced ulcer in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1982, Volume: 80, Issue:3

    Topics: Animals; Atropine; Electromyography; Gastrointestinal Motility; Isoproterenol; Male; Phentolamine; R

1982
Effects of centrally of peripherally injected adrenomedullin on reserpine-induced gastric lesions.
    European journal of pharmacology, 1998, Oct-30, Volume: 360, Issue:1

    Topics: Adrenalectomy; Adrenomedullin; Animals; Anti-Ulcer Agents; Calcitonin Gene-Related Peptide; Calciton

1998
Exacerbation of cold restraint-induced gastric ulcer by GABA in mice.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1996, Volume: 17, Issue:5

    Topics: Adrenergic alpha-Antagonists; Animals; Atropine; Baclofen; Bicuculline; Cold Temperature; GABA Agoni

1996
[Experimental gastric ulcer: changes induced by alpha receptor blockage].
    Archivos de farmacologia y toxicologia, 1976, Volume: 2, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Epinephrine; Gastric Juice; Gastric Mucosa; Phentolamine; Rat

1976
Effects of stress and of autonomic blockers on gastric mucosal microcirculation in rats.
    European journal of pharmacology, 1975, Volume: 30, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Chlorpromazine; Cold T

1975
Effects of various drugs and vagotomy on indomethacin-induced gastric ulcers in the rat.
    Japanese journal of pharmacology, 1979, Volume: 29, Issue:4

    Topics: Aluminum Hydroxide; Amylopectin; Animals; Anti-Ulcer Agents; Atropine; Chlorpromazine; Hexamethonium

1979
Mechanism of stress ulcer. Influence of alpha-adrenergic blockade on stress ulceration and gastric mucosal energy metabolism.
    The American journal of digestive diseases, 1978, Volume: 23, Issue:6

    Topics: Animals; Energy Metabolism; Gastric Mucosa; Male; Phentolamine; Rabbits; Shock, Hemorrhagic; Stomach

1978
The role of aspirin in gastric ulceration . Some factors involved in the development of gastric mucosal damage induced by aspirin in rats exposed to various stress conditions.
    The American journal of digestive diseases, 1978, Volume: 23, Issue:6

    Topics: Animals; Arthritis, Experimental; Aspirin; Atropine Derivatives; Bethanechol Compounds; Cold Tempera

1978
A new model of stress ulcer in the rat with pylorus ligation and its pathogenesis.
    The American journal of digestive diseases, 1976, Volume: 21, Issue:9

    Topics: Amylopectin; Animals; Atropine; Bicarbonates; Chlorpromazine; Disease Models, Animal; Gastric Mucosa

1976
Role of glucocorticoids and catecholamines on hepatic thiobarbituric acid reactants in basal and stress conditions in the rat.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1991, Volume: 23, Issue:3

    Topics: Adrenalectomy; Adrenocorticotropic Hormone; Aldosterone; Analysis of Variance; Animals; Corticostero

1991
Aggravating action of clonidine on ethanol-induced gastric lesions: probable mechanism of action.
    Indian journal of physiology and pharmacology, 1990, Volume: 34, Issue:4

    Topics: Animals; Cimetidine; Clonidine; Drug Synergism; Ethanol; Male; Naloxone; Phentolamine; Rats; Rats, I

1990
Effect of a single dose of phentolamine and mj 1999 on aspirin-induced gastric ulceration in rats.
    The Journal of pharmacy and pharmacology, 1969, Volume: 21, Issue:8

    Topics: Anilides; Animals; Aspirin; Female; Male; Phentolamine; Rats; Stomach Ulcer; Sulfonic Acids; Sympath

1969
Effects of adrenergic blocking agents on gastric secretion and stress-induced gastric ulcer in rats.
    Japanese journal of pharmacology, 1970, Volume: 20, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Depression, Chemical; Dibenzylch

1970
Increased sympathetic activity in the pathogenesis of restraint ulcer in rats.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 184, Issue:1

    Topics: Adrenal Glands; Adrenalectomy; Adrenergic alpha-Antagonists; Animals; Bretylium Compounds; Female; G

1973
Effects of phentolamine mesylate and propranolol hydrochloride on aspirin-induced gastric lesions and gastric secretions in the rat.
    Japanese journal of pharmacology, 1974, Volume: 24, Issue:3

    Topics: Animals; Aspirin; Body Weight; Gastric Mucosa; Male; Phentolamine; Propranolol; Pylorus; Rats; Stoma

1974
Mechanism of ulcerogenic activity of indomethacin and oxyphenbutazone.
    European journal of pharmacology, 1973, Volume: 22, Issue:2

    Topics: Adrenal Glands; Adrenalectomy; Animals; Atropine; Cordotomy; Dose-Response Relationship, Drug; Femal

1973
Studies of the mechanisms involved in the production of stress and stress-atropine ulcers in rats.
    European journal of pharmacology, 1970, Volume: 10, Issue:3

    Topics: Animals; Atropine; Calcium Carbonate; Chlorpromazine; Chondroitin; Dibenzylchlorethamine; Gastric Ju

1970
Effect of a single dose of phentolamine, MJ 1999 and isoproterenol on histmaine-induced gastric ulcer in guinea pigs.
    European journal of pharmacology, 1968, Volume: 2, Issue:4

    Topics: Anilides; Animals; Female; Guinea Pigs; Histamine; Isoproterenol; Male; Phentolamine; Stomach Ulcer;

1968