phentolamine has been researched along with Sleep Apnea Syndromes in 3 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
Sleep Apnea Syndromes: Disorders characterized by multiple cessations of respirations during sleep that induce partial arousals and interfere with the maintenance of sleep. Sleep apnea syndromes are divided into central (see SLEEP APNEA, CENTRAL), obstructive (see SLEEP APNEA, OBSTRUCTIVE), and mixed central-obstructive types.
| Excerpt | Relevance | Reference |
|---|---|---|
| " PWA was significantly reduced during arousal from obstructive sleep apnea (-37." | 3.72 | Finger plethysmography--a method for monitoring finger blood flow during sleep disordered breathing. ( Grote, L; Hedner, J; Kraiczi, H; Zou, D, 2003) |
| "Patients received four cumulative dosage steps of phentolamine (0." | 1.32 | Obstructive apneic events induce alpha-receptor mediated digital vasoconstriction. ( Eder, DN; Grote, L; Hedner, J; Peker, Y; Zou, D, 2004) |
| "To study the effects of airway obstruction (AWO) and arousal on coronary blood flow, mean arterial pressure (MAP), and heart rate, pigs were chronically instrumented with arterial catheters, Doppler flow probes on the left circumflex coronary artery, and electrodes for determination of sleep stages." | 1.29 | Hemodynamic changes associated with obstructive sleep apnea followed by arousal in a porcine model. ( Bergau, DM; Garpestad, E; Kirby, DA; Pinto, JM; Weiss, JW, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grote, L | 2 |
| Zou, D | 2 |
| Kraiczi, H | 1 |
| Hedner, J | 2 |
| Eder, DN | 1 |
| Peker, Y | 1 |
| Pinto, JM | 1 |
| Garpestad, E | 1 |
| Weiss, JW | 1 |
| Bergau, DM | 1 |
| Kirby, DA | 1 |
3 other studies available for phentolamine and Sleep Apnea Syndromes
| Article | Year |
|---|---|
Finger plethysmography--a method for monitoring finger blood flow during sleep disordered breathing.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adult; Apnea; Blood Pressure; Dose-Response | 2003 |
Obstructive apneic events induce alpha-receptor mediated digital vasoconstriction.
Topics: Adrenergic alpha-Antagonists; Adult; Blood Pressure; Body Mass Index; Electroencephalography; Heart | 2004 |
Hemodynamic changes associated with obstructive sleep apnea followed by arousal in a porcine model.
Topics: Airway Obstruction; Animals; Arousal; Blood Pressure; Coronary Circulation; Disease Models, Animal; | 1993 |