phentolamine has been researched along with Sleep Apnea, Obstructive in 2 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
Sleep Apnea, Obstructive: A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients received four cumulative dosage steps of phentolamine (0." | 1.32 | Obstructive apneic events induce alpha-receptor mediated digital vasoconstriction. ( Eder, DN; Grote, L; Hedner, J; Peker, Y; Zou, D, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moradkhan, R | 1 |
| Spitnale, B | 1 |
| McQuillan, P | 1 |
| Hogeman, C | 1 |
| Gray, KS | 1 |
| Leuenberger, UA | 1 |
| Zou, D | 1 |
| Grote, L | 1 |
| Eder, DN | 1 |
| Peker, Y | 1 |
| Hedner, J | 1 |
2 other studies available for phentolamine and Sleep Apnea, Obstructive
| Article | Year |
|---|---|
Hypoxia-induced vasodilation and effects of regional phentolamine in awake patients with sleep apnea.
Topics: Adrenergic alpha-Antagonists; Adult; Autonomic Nerve Block; Brachial Artery; Case-Control Studies; F | 2010 |
Obstructive apneic events induce alpha-receptor mediated digital vasoconstriction.
Topics: Adrenergic alpha-Antagonists; Adult; Blood Pressure; Body Mass Index; Electroencephalography; Heart | 2004 |