phentolamine has been researched along with Pulmonary Edema in 41 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
Pulmonary Edema: Excessive accumulation of extravascular fluid in the lung, an indication of a serious underlying disease or disorder. Pulmonary edema prevents efficient PULMONARY GAS EXCHANGE in the PULMONARY ALVEOLI, and can be life-threatening.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the effect of endogenous bradykinin on adrenaline-induced pulmonary edema (PE) by blocking bradykinin receptors." | 7.71 | The involvement of bradykinin in adrenaline-induced pulmonary edema in rats. ( Hao, Y; Mineshita, S; Okamura, S; Wang, LM, 2001) |
| "This study was performed to demonstrate an experimental procedure of pulmonary edema induced by angiotensin I (AT I) in rats and to elucidate the mechanism of hemodynamic pulmonary edema." | 7.70 | Pulmonary edema induced by angiotensin I in rats. ( Mineshita, S; Shimakura, K; Wang, LM; Xu, ZH; Yamamoto, T, 1998) |
| "We performed this study to demonstrate the experimental procedure for inducing pulmonary edema by angiotensin II (AT II) in rats and to determine the mechanism of hemodynamic pulmonary edema." | 7.69 | Pulmonary edema induced by angiotensin II in rats. ( Mineshita, S; Miyazaki, M; Sanaka, M; Shimakura, K; Wang, L, 1995) |
| "To determine the effect of massive cocaine intoxication on lung water and ascites accumulation and the effect of beta- and alpha-adrenergic blockade on survival in massive cocaine intoxication in the mouse." | 7.67 | Increased lung water and ascites after massive cocaine overdosage in mice and improved survival related to beta-adrenergic blockage. ( Ptashne, KA; Robin, ED; Wong, RJ, 1989) |
| "Ethchlorvynol (10 mg/kg) causes transient pulmonary hypertension and an increased permeability pulmonary edema in sheep." | 7.66 | Indomethacin blunts ethchlorvynol-induced pulmonary hypertension but not pulmonary edema. ( Fairman, RP; Falls, RK; Glauser, FL; Millen, JE, 1982) |
| "Phentolamine in amounts of 10 to 40 microgram/kg/min was infused intravenously for the emergency treatment of acute pulmonary edema due to left ventricular failure." | 7.65 | Afterload reduction with phentolamine in patients with acute pulmonary edema. ( Henning, RJ; Shubin, H; Weil, MH, 1977) |
| "We present a case of NPE caused by an intracranial hemorrhage from a ruptured arteriovenous malformation." | 5.38 | Neurogenic pulmonary edema: successful treatment with IV phentolamine. ( Chawla, LS; Davison, DL; Junker, C; Selassie, L; Seneff, MG; Tevar, R, 2012) |
| "We investigated the effect of endogenous bradykinin on adrenaline-induced pulmonary edema (PE) by blocking bradykinin receptors." | 3.71 | The involvement of bradykinin in adrenaline-induced pulmonary edema in rats. ( Hao, Y; Mineshita, S; Okamura, S; Wang, LM, 2001) |
| "This study was performed to demonstrate an experimental procedure of pulmonary edema induced by angiotensin I (AT I) in rats and to elucidate the mechanism of hemodynamic pulmonary edema." | 3.70 | Pulmonary edema induced by angiotensin I in rats. ( Mineshita, S; Shimakura, K; Wang, LM; Xu, ZH; Yamamoto, T, 1998) |
| "We performed this study to demonstrate the experimental procedure for inducing pulmonary edema by angiotensin II (AT II) in rats and to determine the mechanism of hemodynamic pulmonary edema." | 3.69 | Pulmonary edema induced by angiotensin II in rats. ( Mineshita, S; Miyazaki, M; Sanaka, M; Shimakura, K; Wang, L, 1995) |
| "To determine the effect of massive cocaine intoxication on lung water and ascites accumulation and the effect of beta- and alpha-adrenergic blockade on survival in massive cocaine intoxication in the mouse." | 3.67 | Increased lung water and ascites after massive cocaine overdosage in mice and improved survival related to beta-adrenergic blockage. ( Ptashne, KA; Robin, ED; Wong, RJ, 1989) |
| "Ethchlorvynol (10 mg/kg) causes transient pulmonary hypertension and an increased permeability pulmonary edema in sheep." | 3.66 | Indomethacin blunts ethchlorvynol-induced pulmonary hypertension but not pulmonary edema. ( Fairman, RP; Falls, RK; Glauser, FL; Millen, JE, 1982) |
| "Phentolamine in amounts of 10 to 40 microgram/kg/min was infused intravenously for the emergency treatment of acute pulmonary edema due to left ventricular failure." | 3.65 | Afterload reduction with phentolamine in patients with acute pulmonary edema. ( Henning, RJ; Shubin, H; Weil, MH, 1977) |
| "We present a case of NPE caused by an intracranial hemorrhage from a ruptured arteriovenous malformation." | 1.38 | Neurogenic pulmonary edema: successful treatment with IV phentolamine. ( Chawla, LS; Davison, DL; Junker, C; Selassie, L; Seneff, MG; Tevar, R, 2012) |
| "Phentolamine or FK506 treatment during reperfusion improves alveolar liquid clearance and decreases the severity of lung injury." | 1.35 | Pharmacologic modulation of alveolar liquid clearance in transplanted lungs by phentolamine and FK506. ( Berthiaume, Y; Dagenais, A; Ferraro, P; Sugita, M; VanSpall, M, 2009) |
| "Pretreatment with phentolamine attenuated the pancuronium-induced increase in PAP." | 1.29 | Pancuronium increases pulmonary arterial pressure in lung injury. ( Du, H; Hanaoka, K; Hayashida, M; Hayashita, M; Kin, N; Orii, R; Suwa, K; Yamada, Y, 1996) |
| "High altitude pulmonary edema is characterized hemodynamically by a markedly restricted pulmonary vascular bed." | 1.28 | The effect of vasodilators on pulmonary hemodynamics in high altitude pulmonary edema: a comparison. ( Greene, ER; Hackett, PH; Hartig, GS; Levine, BD; Roach, RC, 1992) |
| "The treatment of acute cardiogenic pulmonary edema is associated with the return of hypo-oncotic fluid from the interstitial compartment back into the intravascular compartment with expansion of plasma volume and reduction of colloid osmotic pressure and hemoglobin concentration." | 1.26 | Effect of afterload reduction on plasma volume during acute heart failure. ( Henning, RJ; Weil, MH, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (68.29) | 18.7374 |
| 1990's | 7 (17.07) | 18.2507 |
| 2000's | 4 (9.76) | 29.6817 |
| 2010's | 2 (4.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moffatt-Bruce, S | 1 |
| Sugita, M | 1 |
| Berthiaume, Y | 1 |
| VanSpall, M | 1 |
| Dagenais, A | 1 |
| Ferraro, P | 1 |
| Davison, DL | 1 |
| Chawla, LS | 1 |
| Selassie, L | 1 |
| Tevar, R | 1 |
| Junker, C | 1 |
| Seneff, MG | 1 |
| Krishnamoorthy, V | 1 |
| Weinberg, G | 1 |
| Hao, Y | 1 |
| Okamura, S | 1 |
| Wang, LM | 2 |
| Mineshita, S | 3 |
| Perret, C | 3 |
| Enrico, JF | 3 |
| WOOD, CD | 1 |
| SEAGER, LD | 1 |
| FERRELL, G | 1 |
| Ram, CV | 1 |
| Liu, XW | 1 |
| Romano, E | 1 |
| Gullo, A | 1 |
| Mocavero, G | 1 |
| Gunnar, RM | 1 |
| Glauser, FL | 1 |
| Fairman, RP | 1 |
| Millen, JE | 1 |
| Falls, RK | 1 |
| Shimakura, K | 2 |
| Sanaka, M | 1 |
| Wang, L | 1 |
| Miyazaki, M | 1 |
| Liu, S | 1 |
| Kuo, HP | 1 |
| Sheppard, MN | 1 |
| Barnes, PJ | 1 |
| Evans, TW | 1 |
| Schraufnagel, DE | 1 |
| Thakkar, MB | 1 |
| Du, H | 1 |
| Orii, R | 1 |
| Yamada, Y | 1 |
| Hayashida, M | 1 |
| Kin, N | 1 |
| Suwa, K | 1 |
| Hanaoka, K | 1 |
| Hayashita, M | 1 |
| Xu, ZH | 1 |
| Yamamoto, T | 1 |
| Henning, RJ | 2 |
| Weil, MH | 2 |
| Tadei, A | 1 |
| Geslin, P | 1 |
| Delhumeau, A | 1 |
| Victor, J | 1 |
| Le Douarin, L | 1 |
| Richard, M | 1 |
| Shubin, H | 1 |
| Dunning, AJ | 1 |
| Nathan, MA | 1 |
| Reis, DJ | 1 |
| Hackett, PH | 1 |
| Roach, RC | 1 |
| Hartig, GS | 1 |
| Greene, ER | 1 |
| Levine, BD | 1 |
| Brimacombe, J | 1 |
| Archdeacon, J | 1 |
| Newell, S | 1 |
| Martin, J | 1 |
| Robin, ED | 1 |
| Wong, RJ | 1 |
| Ptashne, KA | 1 |
| Renard, M | 1 |
| Verhoeven, A | 1 |
| Liebens, I | 1 |
| Bernard, R | 1 |
| Guarini, S | 1 |
| Baggio, G | 1 |
| Ferrari, W | 1 |
| Antonio, MP | 1 |
| Fernandes, F | 1 |
| Gonçalves, JA | 1 |
| Rocha e Silva, M | 1 |
| Gardaz, JP | 1 |
| Reynaert, M | 1 |
| Grimbert, F | 1 |
| Stepanek, J | 1 |
| Brunner, E | 1 |
| RamÃrez, A | 1 |
| Abelmann, WH | 1 |
| Nolte, H | 1 |
| von Schnakenburg, K | 1 |
| Batts, JA | 1 |
| Tchilinguirian, NG | 1 |
| Passmore, J | 1 |
| Hammond, RE | 1 |
| Akers, TK | 1 |
| Naess, K | 1 |
| Gould, L | 3 |
| Zahir, M | 1 |
| Shariff, M | 1 |
| Giuliani, M | 1 |
| Poli, S | 1 |
| Grandjean, T | 1 |
| Korec, R | 2 |
4 reviews available for phentolamine and Pulmonary Edema
| Article | Year |
|---|---|
Manipulating afterload for the treatment of acute heart failure. A historical summary.
Topics: Acute Disease; Angiotensins; Animals; Cardiac Catheterization; Cardiac Output; Cardiac Volume; Heart | 2003 |
Hypertensive crisis.
Topics: Antihypertensive Agents; Brain Diseases; Cerebrovascular Disorders; Clonidine; Coronary Disease; Dia | 1984 |
The role of vasodilating agents in the treatment of chronic heart failure.
Topics: Cardiac Output; Chronic Disease; Dobutamine; Heart Failure; Humans; Muscle Contraction; Nitroprussid | 1980 |
Cardiac decompensation.
Topics: Acute Disease; Aminophylline; Assisted Circulation; Cardiac Glycosides; Digoxin; Diuretics; Electric | 1974 |
1 trial available for phentolamine and Pulmonary Edema
| Article | Year |
|---|---|
[Phentolamine in treatment of acute left ventricular insufficiancies].
Topics: Acid-Base Equilibrium; Adult; Aged; Blood Gas Analysis; Blood Pressure; Clinical Trials as Topic; Di | 1975 |
36 other studies available for phentolamine and Pulmonary Edema
| Article | Year |
|---|---|
Invited commentary.
Topics: Adrenergic alpha-Antagonists; Animals; Dogs; Extravascular Lung Water; Graft Survival; Immunosuppres | 2009 |
Pharmacologic modulation of alveolar liquid clearance in transplanted lungs by phentolamine and FK506.
Topics: Adrenergic alpha-Antagonists; Animals; Dogs; Extravascular Lung Water; Immunosuppressive Agents; Lun | 2009 |
Neurogenic pulmonary edema: successful treatment with IV phentolamine.
Topics: Adrenergic alpha-Antagonists; Catecholamines; Humans; Infusions, Intravenous; Intracranial Hemorrhag | 2012 |
Phentolamine for neurogenic pulmonary edema: bench to bedside progress.
Topics: Adrenergic alpha-Antagonists; Humans; Male; Phentolamine; Pulmonary Edema | 2012 |
The involvement of bradykinin in adrenaline-induced pulmonary edema in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; | 2001 |
INFLUENCE OF AUTONOMIC BLOCKADE ON ACONITINE INDUCED PULMONARY EDEMA.
Topics: Aconitine; Aconitum; Atropine; Autonomic Nerve Block; Blood Pressure; Blood Pressure Determination; | 1964 |
[Possible mechanism of the therapeutic effect of phentolamine in the adult respiratory distress syndrome--a preliminary study on oleic acid lung preparations].
Topics: Animals; Dogs; Hemodynamics; Oleic Acid; Oleic Acids; Phentolamine; Pulmonary Edema; Respiratory Dis | 1984 |
[Acute pulmonary edema. Clinical experience in re-evaluation of the therapeutic role of chlorpromazine].
Topics: Aged; Chlorpromazine; Heart Diseases; Heart Failure; Humans; Intermittent Positive-Pressure Ventilat | 1981 |
Indomethacin blunts ethchlorvynol-induced pulmonary hypertension but not pulmonary edema.
Topics: Animals; Blood Pressure; Diphenhydramine; Ethchlorvynol; Hypertension, Pulmonary; Indomethacin; Phen | 1982 |
Pulmonary edema induced by angiotensin II in rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Disease Models, Animal; D | 1995 |
Vagal stimulation induces increased pulmonary vascular permeability in guinea pig.
Topics: Animals; Arginine; Atropine; Blood Pressure; Capillary Permeability; Capsaicin; Catecholamines; Dose | 1994 |
Pulmonary venous sphincter constriction is attenuated by alpha-adrenergic antagonism.
Topics: Animals; Brain Injuries; Corrosion Casting; Craniocerebral Trauma; Female; Lymphatic System; Male; M | 1993 |
Pancuronium increases pulmonary arterial pressure in lung injury.
Topics: Animals; Blood Pressure; Cardiac Output; Dogs; Female; Male; Neuromuscular Nondepolarizing Agents; O | 1996 |
Pulmonary edema induced by angiotensin I in rats.
Topics: Adrenergic alpha-Antagonists; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti | 1998 |
Effect of afterload reduction on plasma volume during acute heart failure.
Topics: Acute Disease; Aged; Blood Pressure; Cardiac Output; Coronary Disease; Diastole; Drug Evaluation; Fe | 1978 |
Afterload reduction with phentolamine in patients with acute pulmonary edema.
Topics: Acute Disease; Aged; Blood Pressure; Cardiac Output; Dose-Response Relationship, Drug; Female; Heart | 1977 |
[A patient with a decompensated heart].
Topics: Digoxin; Diuretics; Heart Failure; Humans; Male; Middle Aged; Oxygen Inhalation Therapy; Phentolamin | 1976 |
Fulminating arterial hypertension with pulmonary edema from release of adrenomedullary catecholamines after lesions of the anterior hypothalamus in the rat.
Topics: Adrenal Medulla; Adrenalectomy; Animals; Blood Pressure; Body Temperature; Cardiac Output; Catechola | 1975 |
The effect of vasodilators on pulmonary hemodynamics in high altitude pulmonary edema: a comparison.
Topics: Altitude Sickness; Echocardiography, Doppler; Hemodynamics; Humans; Hydralazine; Nifedipine; Phentol | 1992 |
Two cases of naloxone-induced pulmonary oedema--the possible use of phentolamine in management.
Topics: Adolescent; Aged; Bronchial Spasm; Furosemide; Humans; Hydrocortisone; Male; Midazolam; Naloxone; Ph | 1991 |
Increased lung water and ascites after massive cocaine overdosage in mice and improved survival related to beta-adrenergic blockage.
Topics: Animals; Ascites; Cocaine; Extracellular Space; Lung; Male; Mice; Phentolamine; Propranolol; Pulmona | 1989 |
Blood gas and hemodynamic changes induced by the treatment of pulmonary congestion with vasodilators in the acute phase of myocardial infarction.
Topics: Adult; Aged; Carbon Dioxide; Female; Heart Failure; Hemodynamics; Humans; Hypertension, Pulmonary; I | 1986 |
Studies on epinephrine-induced lung edema in the rat. II. Hemodynamic changes.
Topics: Animals; Blood Pressure; Epinephrine; Female; Heart Ventricles; Infusions, Parenteral; Phentolamine; | 1986 |
Pharmacologial analysis of the mediators involved in the acute pulmonary edema produced in rats by adrenaline.
Topics: Animals; Cyproheptadine; Diphenhydramine; Epinephrine; Histamine H1 Antagonists; Phenoxybenzamine; P | 1973 |
[Phentolamine in the treatment of left heart failure in the acute stage of myocardial infarct. Hemodynamic study; preliminary results].
Topics: Blood Pressure; Heart Failure; Heart Rate; Humans; Hypertension, Pulmonary; Myocardial Infarction; P | 1974 |
Effect of pretreatment with phentolamine on experimentally induced Euler-Liljestrand reflex.
Topics: Acid-Base Equilibrium; Animals; Arteries; Carbon Dioxide; Cardiac Catheterization; Cardiac Output; D | 1974 |
[Morphological and pharmacological-toxicological aspects of hyperoxia].
Topics: Aminobutyrates; Animals; Atmospheric Pressure; Brain Diseases; Diazepam; Ganglia; Humans; Lung; Lung | 1973 |
Pheochromocytoma in pregnancy: a case report and review of the pathophysiology.
Topics: Adrenal Gland Neoplasms; Adult; Catecholamines; Cesarean Section; Epinephrine; Female; Heart Arrest; | 1974 |
Effect of adrenergic drugs on pulmonary responses to high-pressure oxygen.
Topics: Animals; Atmospheric Pressure; Catecholamines; Cocaine; Drug Combinations; Hemodynamics; Imipramine; | 1974 |
[Pulmonary edema. Treatment with an alpha blockader].
Topics: Humans; Phentolamine; Pulmonary Edema | 1971 |
Phentolamine: use in pulmonary edema. Preliminary report.
Topics: Aged; Blood Pressure; Cardiac Output; Electrocardiography; Heart Failure; Humans; Injections, Intrav | 1970 |
[Use of phentolamine in the treatment of acute pulmonary edema. Preliminary results].
Topics: Acidosis; Acute Disease; Blood Pressure; Hemoglobins; Humans; Perfusion; Phentolamine; Pulmonary Ede | 1971 |
[Post-insulin hypoglycemic pulmonary edema in rats].
Topics: Animals; Female; Hypoglycemia; Insulin; Male; Phenoxybenzamine; Phentolamine; Pulmonary Edema; Rats | 1968 |
[The protective and noxious effect of catecholamines during postinsulin hypoglycemia in rats].
Topics: Adrenal Medulla; Animals; Cardiovascular System; Catecholamines; Ergotamine; Fasting; Female; Hypogl | 1968 |
Phentolamine--rediscovery of an old drug.
Topics: Animals; Arrhythmias, Cardiac; Dogs; Heart; Hemodynamics; Humans; Injections, Intravenous; Phentolam | 1969 |
Appraisal and reappraisal of cardiac therapy. Edited by Arthur C. DeGraff, Alan F. Lyon, and Julian Frieden. Phentolamine.
Topics: Animals; Arrhythmias, Cardiac; Bronchodilator Agents; Dogs; Heart Diseases; Hemodynamics; Phentolami | 1969 |