phentolamine has been researched along with Prostatic Neoplasms, Castration-Resistant in 1 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
Prostatic Neoplasms, Castration-Resistant: Tumors or cancer of the PROSTATE which can grow in the presence of low or residual amount of androgen hormones such as TESTOSTERONE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phentolamine has a simple chemical structure and is not a P-gp substrate." | 1.42 | Repurposing of phentolamine as a potential anticancer agent against human castration-resistant prostate cancer: A central role on microtubule stabilization and mitochondrial apoptosis pathway. ( Chang, WL; Chao, CC; Guh, JH; Ho, CH; Hsu, JL; Hsu, LC; Liu, SP, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ho, CH | 1 |
| Hsu, JL | 1 |
| Liu, SP | 1 |
| Hsu, LC | 1 |
| Chang, WL | 1 |
| Chao, CC | 1 |
| Guh, JH | 1 |
1 other study available for phentolamine and Prostatic Neoplasms, Castration-Resistant
| Article | Year |
|---|---|
Repurposing of phentolamine as a potential anticancer agent against human castration-resistant prostate cancer: A central role on microtubule stabilization and mitochondrial apoptosis pathway.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Repositioni | 2015 |