phentolamine has been researched along with Peripheral Nerve Diseases in 10 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To test for the presence of "sympathetically maintained pain" (SMP), we administered placebo-controlled phentolamine sympathetic blocks to 14 patients with painful polyneuropathies." | 9.07 | Phentolamine sympathetic block in painful polyneuropathies. II. Further questioning of the concept of 'sympathetically maintained pain'. ( Campero, M; Ochoa, JL; Verdugo, RJ, 1994) |
| ") significantly attenuated cold allodynia whereas yohimbine (alpha2-adrenoreceptor antagonist, 0." | 7.73 | Individual differences in the sensitivity of cold allodynia to phentolamine in neuropathic rats. ( Hwang, BG; Kim, JH; Kim, SK; Min, BI; Na, HS; Park, DS; Yoo, GY, 2005) |
| "To test for the presence of "sympathetically maintained pain" (SMP), we administered placebo-controlled phentolamine sympathetic blocks to 14 patients with painful polyneuropathies." | 5.07 | Phentolamine sympathetic block in painful polyneuropathies. II. Further questioning of the concept of 'sympathetically maintained pain'. ( Campero, M; Ochoa, JL; Verdugo, RJ, 1994) |
| ") significantly attenuated cold allodynia whereas yohimbine (alpha2-adrenoreceptor antagonist, 0." | 3.73 | Individual differences in the sensitivity of cold allodynia to phentolamine in neuropathic rats. ( Hwang, BG; Kim, JH; Kim, SK; Min, BI; Na, HS; Park, DS; Yoo, GY, 2005) |
| "The effects of transcutaneous electrical stimulation and systemic injection of phentolamine, a non-specific alpha-adrenergic antagonist, on the behavioral signs of mechanical allodynia and cold hyperalgesia in rats with nerve injury were investigated." | 3.71 | Differential antinociceptive effect of transcutaneous electrical stimulation on pain behavior sensitive or insensitive to phentolamine in neuropathic rats. ( Choi, Y; Leem, JW; Nam, TS; Paik, KS; Yeon, DS, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 6 (60.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, SK | 1 |
| Min, BI | 1 |
| Kim, JH | 1 |
| Hwang, BG | 1 |
| Yoo, GY | 1 |
| Park, DS | 1 |
| Na, HS | 3 |
| Hama, AT | 1 |
| Sagen, J | 1 |
| Verdugo, RJ | 1 |
| Campero, M | 1 |
| Ochoa, JL | 1 |
| Kim, SH | 1 |
| Kwangsup, S | 1 |
| Jin, MC | 1 |
| Breivik, H | 1 |
| Kim, HJ | 1 |
| Sung, B | 1 |
| Hong, SK | 1 |
| Park, SK | 1 |
| Chung, K | 1 |
| Chung, JM | 1 |
| Nam, TS | 1 |
| Choi, Y | 1 |
| Yeon, DS | 1 |
| Leem, JW | 1 |
| Paik, KS | 1 |
| Xie, YK | 1 |
| Xiao, WH | 1 |
| Spath, P | 1 |
| Dittrich, P | 1 |
| Sailer, S | 1 |
| Sandhofer, F | 1 |
1 trial available for phentolamine and Peripheral Nerve Diseases
| Article | Year |
|---|---|
Phentolamine sympathetic block in painful polyneuropathies. II. Further questioning of the concept of 'sympathetically maintained pain'.
Topics: Adult; Aged; Autonomic Nerve Block; Double-Blind Method; Female; Humans; Male; Middle Aged; Nerve Bl | 1994 |
9 other studies available for phentolamine and Peripheral Nerve Diseases
| Article | Year |
|---|---|
Individual differences in the sensitivity of cold allodynia to phentolamine in neuropathic rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-A | 2005 |
Alleviation of neuropathic pain symptoms by xenogeneic chromaffin cell grafts in the spinal subarachnoid space.
Topics: Adrenal Medulla; Animals; Body Temperature; Cattle; Chromaffin System; Cold Temperature; Hindlimb; M | 1994 |
Effects of sympathectomy on a rat model of peripheral neuropathy.
Topics: Animals; Disease Models, Animal; Guanethidine; Hot Temperature; Male; Pain; Pain Measurement; Periph | 1993 |
Chronic pain and the sympathetic nervous system.
Topics: Autonomic Nervous System Diseases; Causalgia; Chronic Disease; Clinical Trials as Topic; Double-Blin | 1997 |
Amount of sympathetic sprouting in the dorsal root ganglia is not correlated to the level of sympathetic dependence of neuropathic pain in a rat model.
Topics: Adrenergic alpha-Antagonists; Animals; Ganglia, Spinal; Histocytochemistry; Male; Pain; Pain Measure | 1998 |
Effects of purinergic and adrenergic antagonists in a rat model of painful peripheral neuropathy.
Topics: Adrenergic alpha-Antagonists; Animals; Antineoplastic Agents; Disease Models, Animal; Drug Therapy, | 2000 |
Differential antinociceptive effect of transcutaneous electrical stimulation on pain behavior sensitive or insensitive to phentolamine in neuropathic rats.
Topics: Adrenergic alpha-Antagonists; Animals; Cold Temperature; Hindlimb; Hyperalgesia; Male; Pain Measurem | 2001 |
Electrophysiological evidence for hyperalgesia in the peripheral neuropathy.
Topics: Animals; Electrophysiology; Hyperalgesia; Hyperesthesia; Nerve Fibers; Norepinephrine; Peripheral Ne | 1990 |
[Effect of phentolamine on the glucose metabolism in normal persons and patients with chronic kidney insufficiency].
Topics: Adult; Aged; Blood Glucose; Blood Urea Nitrogen; Bronchiectasis; Bronchitis; Chronic Disease; Female | 1970 |