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phentolamine and Pancreatic Neoplasms

phentolamine has been researched along with Pancreatic Neoplasms in 5 studies

Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.

Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).

Research Excerpts

ExcerptRelevanceReference
"This case report series describes eight patients (four patients with pancreatic carcinoma, one patient with hepatocellular carcinoma, one patient with gastric and rectal carcinoma, one with sigmoid colon cancer, and one with rectal cancer), whose abdominal cancer pain was treated with intravenous phentolamine infusion at 80 mg x day(-1) for 2 days."7.74Intravenous phentolamine infusion alleviates the pain of abdominal visceral cancer, including pancreatic carcinoma. ( Kamiizumi, Y; Yasukawa, K; Yasukawa, M; Yokoyama, R, 2007)
"This case report describes the successful alleviation of the pain of pancreatic carcinoma with intravenous phentolamine mesylate."7.69Intravenous phentolamine mesylate alleviates the pain of pancreatic carcinoma. ( McCleane, GJ, 1997)
"This case report series describes eight patients (four patients with pancreatic carcinoma, one patient with hepatocellular carcinoma, one patient with gastric and rectal carcinoma, one with sigmoid colon cancer, and one with rectal cancer), whose abdominal cancer pain was treated with intravenous phentolamine infusion at 80 mg x day(-1) for 2 days."3.74Intravenous phentolamine infusion alleviates the pain of abdominal visceral cancer, including pancreatic carcinoma. ( Kamiizumi, Y; Yasukawa, K; Yasukawa, M; Yokoyama, R, 2007)
"This case report describes the successful alleviation of the pain of pancreatic carcinoma with intravenous phentolamine mesylate."3.69Intravenous phentolamine mesylate alleviates the pain of pancreatic carcinoma. ( McCleane, GJ, 1997)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's3 (60.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
RUNGE, TM1
Yasukawa, M1
Yasukawa, K1
Kamiizumi, Y1
Yokoyama, R1
Hirose, H1
Seto, Y1
Maruyama, H1
Dan, K1
Nakamura, K1
Saruta, T1
McCleane, GJ1
Chapman, JC1
McClenaghan, NH1
Cosgrove, KE1
Hashmi, MN1
Shepherd, RM1
Giesberts, AN1
White, SJ1
Ammälä, C1
Flatt, PR1
Dunne, MJ1

Other Studies

5 other studies available for phentolamine and Pancreatic Neoplasms

ArticleYear
Phentolamine (regitine) methanesulfonate test in pancreatic adenoma.
    Journal of the American Medical Association, 1958, Mar-22, Volume: 166, Issue:12

    Topics: Adenoma; Mesylates; Pancreatic Neoplasms; Phentolamine; Sympatholytics

1958
Intravenous phentolamine infusion alleviates the pain of abdominal visceral cancer, including pancreatic carcinoma.
    Journal of anesthesia, 2007, Volume: 21, Issue:3

    Topics: Abdominal Pain; Aged; Analgesics, Non-Narcotic; Carcinoma; Digestive System Neoplasms; Female; Gastr

2007
Effects of alpha 2-adrenergic agonism, imidazolines, and G-protein on insulin secretion in beta cells.
    Metabolism: clinical and experimental, 1997, Volume: 46, Issue:10

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agon

1997
Intravenous phentolamine mesylate alleviates the pain of pancreatic carcinoma.
    Pain, 1997, Volume: 73, Issue:2

    Topics: Adult; Analgesics, Non-Narcotic; Humans; Infusions, Intravenous; Male; Pain; Pancreatic Neoplasms; P

1997
ATP-sensitive potassium channels and efaroxan-induced insulin release in the electrofusion-derived BRIN-BD11 beta-cell line.
    Diabetes, 1999, Volume: 48, Issue:12

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Benzofurans; C

1999