phentolamine has been researched along with Pain in 102 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of our work is to evaluate the efficacy of intracavernous sodium nitroprusside (SNP) in management of erectile dysfunction (ED) in a clinical comparative study with papaverine/phentolamine in ED patients." | 9.11 | Intracavernous sodium nitroprusside (SNP) versus papaverine/phentolamine in erectile dysfunction: a comparative study of short-term efficacy and side-effects. ( Abdelsalam, W; Atteya, A; Elnashaar, A; Gadallah, A; Shamloul, R; Zohdy, W, 2005) |
| "The objective of our study was to clarify whether the phentolamine test is as suitable as sympathetic blockade in diagnosing cases of sympathetically maintained pain." | 9.10 | [Sympathetically maintained pain (SMP): phentolamine test vs sympathetic nerve blockade. Comparison of two diagnostic methods]. ( Kohn, D; Larsen, B; Müller, B; Wehnert, Y, 2002) |
| "To test for the presence of "sympathetically maintained pain" (SMP), we administered placebo-controlled phentolamine sympathetic blocks to 14 patients with painful polyneuropathies." | 9.07 | Phentolamine sympathetic block in painful polyneuropathies. II. Further questioning of the concept of 'sympathetically maintained pain'. ( Campero, M; Ochoa, JL; Verdugo, RJ, 1994) |
| "In an attempt to determine whether penile pain associated with intracorporeal injections could be due to the acidity of the medication, we performed a randomized study comparing the incidence of penile pain following intracorporeal injections with or without the addition of sodium bicarbonate to the intracorporeal medications." | 9.07 | Sodium bicarbonate alleviates penile pain induced by intracavernous injections for erectile dysfunction. ( Moriel, EZ; Rajfer, J, 1993) |
| "The efficacy of papaverine, and a combination of papaverine and phentolamine as a pharmacological treatment of impotence was compared in a double-blind, crossover trial." | 9.06 | Treatment of impotence by intrapenile injections. A comparison of papaverine versus papaverine and phentolamine: a double-blind, crossover trial. ( Carati, CJ; Earle, CM; Keogh, EJ; Lord, DJ; Tulloch, GS; Watters, GR; Wisniewski, ZS, 1989) |
| "To examine the antagonization of phentolamine against the effects of norepinephrine (NE) on the activity of pain-related neurons in the parafascicular nucleus of morphine-dependent rats." | 7.74 | [Phentolamine antagonizes the effects of norepinephrine on the activity of pain-related neurons in the parafascicular nucleus of morphine-dependent rats]. ( Guan, YZ; Jin, XD; Xu, MY; Yue, WJ; Zhang, SJ, 2008) |
| ") significantly attenuated cold allodynia whereas yohimbine (alpha2-adrenoreceptor antagonist, 0." | 7.73 | Individual differences in the sensitivity of cold allodynia to phentolamine in neuropathic rats. ( Hwang, BG; Kim, JH; Kim, SK; Min, BI; Na, HS; Park, DS; Yoo, GY, 2005) |
| "To report a case in which complete relief of pain associated with gastroparesis, with promotion of gastric emptying, was achieved with administration of phentolamine." | 7.73 | Relief of acute pain in chronic idiopathic gastroparesis with intravenous phentolamine. ( Abell, T; Johnson, A; Lerant, A; Phillips, WJ; Tollefson, B, 2006) |
| "This case report describes the successful alleviation of the pain of pancreatic carcinoma with intravenous phentolamine mesylate." | 7.69 | Intravenous phentolamine mesylate alleviates the pain of pancreatic carcinoma. ( McCleane, GJ, 1997) |
| ") infusion of large doses of phentolamine as an outpatient diagnostic tool for sympathetically maintained pain was studied retrospectively in 100 consecutive patients (73 females and 27 males) with chronic pain." | 7.68 | The safety of intravenous phentolamine administration in patients with neuropathic pain. ( Bourke, DL; Cameron, LB; Raja, SN; Shir, Y, 1993) |
| "The aim of our work is to evaluate the efficacy of intracavernous sodium nitroprusside (SNP) in management of erectile dysfunction (ED) in a clinical comparative study with papaverine/phentolamine in ED patients." | 5.11 | Intracavernous sodium nitroprusside (SNP) versus papaverine/phentolamine in erectile dysfunction: a comparative study of short-term efficacy and side-effects. ( Abdelsalam, W; Atteya, A; Elnashaar, A; Gadallah, A; Shamloul, R; Zohdy, W, 2005) |
| "The objective of our study was to clarify whether the phentolamine test is as suitable as sympathetic blockade in diagnosing cases of sympathetically maintained pain." | 5.10 | [Sympathetically maintained pain (SMP): phentolamine test vs sympathetic nerve blockade. Comparison of two diagnostic methods]. ( Kohn, D; Larsen, B; Müller, B; Wehnert, Y, 2002) |
| "Systemic phentolamine administration has been suggested as a diagnostic tool for identifying patients with sympathetically maintained pain (SMP) (Raja et al." | 5.08 | Monitoring adequacy of alpha-adrenoceptor blockade following systemic phentolamine administration. ( Campbell, JN; Meleka, S; Raja, SN; Turnquist, JL, 1996) |
| "To test the hypothesis that vascular pain depends on sympathetic drive under physiological conditions we studied the effects of both alpha-adrenoceptor stimulation by noradrenaline and alpha-adrenoceptor blockade by phentolamine on the intensity of physicochemically evoked pain from veins in humans." | 5.08 | Nociception from blood vessels is independent of the sympathetic nervous system under physiological conditions in humans. ( Holthusen, H; Kindgen-Milles, D, 1997) |
| "Transurethral alprostadil therapy is an effective therapeutic option for patients with erectile dysfunction and may even "rescue" some patients who have failed prior intracavernous injection therapy." | 5.08 | Transurethral alprostadil as therapy for patients who withdrew from or failed prior intracavernous injection therapy. ( Engel, JD; McVary, KT, 1998) |
| "In an attempt to determine whether penile pain associated with intracorporeal injections could be due to the acidity of the medication, we performed a randomized study comparing the incidence of penile pain following intracorporeal injections with or without the addition of sodium bicarbonate to the intracorporeal medications." | 5.07 | Sodium bicarbonate alleviates penile pain induced by intracavernous injections for erectile dysfunction. ( Moriel, EZ; Rajfer, J, 1993) |
| "To test for the presence of "sympathetically maintained pain" (SMP), we administered placebo-controlled phentolamine sympathetic blocks to 14 patients with painful polyneuropathies." | 5.07 | Phentolamine sympathetic block in painful polyneuropathies. II. Further questioning of the concept of 'sympathetically maintained pain'. ( Campero, M; Ochoa, JL; Verdugo, RJ, 1994) |
| "The efficacy of papaverine, and a combination of papaverine and phentolamine as a pharmacological treatment of impotence was compared in a double-blind, crossover trial." | 5.06 | Treatment of impotence by intrapenile injections. A comparison of papaverine versus papaverine and phentolamine: a double-blind, crossover trial. ( Carati, CJ; Earle, CM; Keogh, EJ; Lord, DJ; Tulloch, GS; Watters, GR; Wisniewski, ZS, 1989) |
| "This study examined the effects of norepinephrine (NE) and phentolamine on the electrical activities of pain-excited neurons (PENs) and pain-inhibited neurons (PINs) in the nucleus accumbens (NAc) of Wistar rats." | 3.77 | Effects of norepinephrine on the electrical activities of pain-related neurons in the rat nucleus accumbens. ( Gao, HR; Jiao, RS; Liang, Y; Xu, MY; Yang, CX; Yang, DX; Zhai, Y; Zhang, D; Zhang, GW; Zhang, H; Zhang, Y, 2011) |
| "To examine the antagonization of phentolamine against the effects of norepinephrine (NE) on the activity of pain-related neurons in the parafascicular nucleus of morphine-dependent rats." | 3.74 | [Phentolamine antagonizes the effects of norepinephrine on the activity of pain-related neurons in the parafascicular nucleus of morphine-dependent rats]. ( Guan, YZ; Jin, XD; Xu, MY; Yue, WJ; Zhang, SJ, 2008) |
| ") significantly attenuated cold allodynia whereas yohimbine (alpha2-adrenoreceptor antagonist, 0." | 3.73 | Individual differences in the sensitivity of cold allodynia to phentolamine in neuropathic rats. ( Hwang, BG; Kim, JH; Kim, SK; Min, BI; Na, HS; Park, DS; Yoo, GY, 2005) |
| " A 58-year-old man with multiple arthritis of rheumatic arthritis and fibromyalgia had headache, nausea, and vomiting all day after ketamine test." | 3.73 | [Postponed or canceled drug challenge tests and side effects of the test drug--a report of four cases]. ( Ann, Y; Arita, H; Asahara, M; Hanaoka, K; Kawamura, G; Mizuno, J; Sekiyama, H, 2006) |
| "To report a case in which complete relief of pain associated with gastroparesis, with promotion of gastric emptying, was achieved with administration of phentolamine." | 3.73 | Relief of acute pain in chronic idiopathic gastroparesis with intravenous phentolamine. ( Abell, T; Johnson, A; Lerant, A; Phillips, WJ; Tollefson, B, 2006) |
| "The purpose of this study is to investigate the mechanisms of the effect of hyperventilation on the spinal pain modulating system by using phentolamine." | 3.69 | [Effects of hyperventilation upon the spinal pain modulating system (third report)]. ( Hanaoka, K; Ide, Y; Nagase, M; Numata, K; Tagami, M; Yamamura, H, 1994) |
| "A comparative study of the effects of sympathetic blockade by stellate ganglion block (SGB) and intravenous phentolamine infusion (PhI) was carried out in 24 patients with presumed sympathetically maintained pain of an upper extremity." | 3.69 | The interpretation of pain relief and sensory changes following sympathetic blockade. ( Allen, RR; Dellemijn, PL; Fields, HL; McKay, WR; Rowbotham, MC, 1994) |
| "This case report describes the successful alleviation of the pain of pancreatic carcinoma with intravenous phentolamine mesylate." | 3.69 | Intravenous phentolamine mesylate alleviates the pain of pancreatic carcinoma. ( McCleane, GJ, 1997) |
| ") infusion of large doses of phentolamine as an outpatient diagnostic tool for sympathetically maintained pain was studied retrospectively in 100 consecutive patients (73 females and 27 males) with chronic pain." | 3.68 | The safety of intravenous phentolamine administration in patients with neuropathic pain. ( Bourke, DL; Cameron, LB; Raja, SN; Shir, Y, 1993) |
| "A total of 78 patients 17 to 84 years old reported their experience via questionnaire with the papaverine-phentolamine injection technique for impotence." | 3.67 | Intracavernous self-injection for impotence: a long-term therapeutic option? Experience in 78 patients. ( Bruskewitz, RC; Feyzi, J; Gasser, TC; Girdley, FM; Graversen, PH, 1988) |
| "In phentolamine-treated patients, ST-segment changes and cardiac pain severity during the second inflation were similar to those observed during the first inflation (13+/-9 versus 12+/-8 mm, P=NS, and 51+/-34 versus 54+/-32 mm, P=NS, respectively), whereas in placebo-treated patients, they were significantly less (6+/-4 versus 13+/-7 mm, P<." | 2.68 | Phentolamine prevents adaptation to ischemia during coronary angioplasty: role of alpha-adrenergic receptors in ischemic preconditioning. ( Chiariello, L; Crea, F; De Paulis, R; Gaspardone, A; Ghini, AS; Gioffrè, PA; Tomai, F; Versaci, F, 1997) |
| "Phentolamine was added to investigate the antinociceptive effect of dibucaine coinjected with epinephrine." | 1.51 | Phentolamine Reverses Epinephrine-Enhanced Skin Antinociception of Dibucaine in Rats. ( Chen, YW; Chiu, CC; Chou, AK; Hung, CH; Wang, JJ, 2019) |
| "Propranolol has anti-inflammatory effects that contribute to its antinociceptive action in the TMJ of females." | 1.48 | Anti-inflammatory effects of propranolol in the temporomandibular joint of female rats and its contribution to antinociceptive action. ( Dias, EV; Parada, CA; Sartori, CR; Tambeli, CH; Teixeira, JM; Zanelatto, FB, 2018) |
| "pretreatment with phentolamine and cyproheptadine caused a reduction of Fos-like immunoreactive neurons of only 4% on the intact side, namely, the differences in the number of Fos-like immunoreactive neurons on two sides of the lumbar spinal cord owing to the unilateral dorsolateral funiculus lesion were nearly abolished by i." | 1.30 | Effects of intrathecal monoamine antagonists on the nociceptive c-Fos expression in a lesioned rat spinal cord. ( Dafny, N; Liu, RJ; Nie, H; Qiao, JT; Wang, R; Zhang, RX, 1997) |
| "Morphine and clonidine were given intrathecally through implanted catheters alone or in a 1:3 fixed ratio." | 1.30 | Synergistic antinociceptive interactions of morphine and clonidine in rats with nerve-ligation injury. ( Bian, D; Lopez, Y; Nichols, ML; Ossipov, MH; Porreca, F, 1997) |
| "Results revealed that adjuvant arthritis produced significant hyperventilation in animals with control transplants, as indicated by increased tidal volumes and minute ventilation, which paralleled the progression of the inflammatory process." | 1.29 | Attenuation of pain-related hyperventilation in adjuvant arthritic rats with adrenal medullary transplants in the spinal subarachnoid space. ( Sagen, J; Wang, H, 1995) |
| "Caffeine did not produce an anti-inflammatory effect as determined by hindpaw plethysmometry, suggesting that antinociception was not secondary to an anti-inflammatory action." | 1.29 | Caffeine antinociception in the rat hot-plate and formalin tests and locomotor stimulation: involvement of noradrenergic mechanisms. ( Doak, GJ; Reid, AR; Sawynok, J, 1995) |
| "A peripheral neuropathy with hyperalgesia and allodynia was produced by loosely tying constrictive ligature around the left sciatic nerve of rats, i." | 1.29 | Inhibitory effect of anisodamine on the neuropathic hyperalgesia following peripheral nerve injury (II). ( Xiao, WH; Xie, YK, 1993) |
| "Bradykinin (BK) is a potent algesic compound." | 1.28 | Bradykinin modulation of a spinal nociceptive reflex in the rat. ( Bauer, MB; Gebhart, GF; Meller, ST, 1992) |
| " Dose-response curves for IT morphine were obtained in the presence of fixed doses (0." | 1.28 | Interaction of intrathecal morphine and ST-91 on antinociception in the rat: dose-response analysis, antagonism and clearance. ( Monasky, MS; Stevens, CW; Yaksh, TL; Zinsmeister, AR, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (27.45) | 18.7374 |
| 1990's | 50 (49.02) | 18.2507 |
| 2000's | 14 (13.73) | 29.6817 |
| 2010's | 10 (9.80) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zanelatto, FB | 1 |
| Dias, EV | 1 |
| Teixeira, JM | 1 |
| Sartori, CR | 1 |
| Parada, CA | 1 |
| Tambeli, CH | 1 |
| Chou, AK | 1 |
| Chiu, CC | 1 |
| Chen, YW | 1 |
| Wang, JJ | 1 |
| Hung, CH | 1 |
| Nelson, CJ | 1 |
| Hsiao, W | 1 |
| Balk, E | 1 |
| Narus, J | 1 |
| Tal, R | 1 |
| Bennett, NE | 1 |
| Mulhall, JP | 1 |
| Nie, TW | 1 |
| Shukkoor, MS | 1 |
| Nair, RS | 1 |
| Amiruddin, FK | 1 |
| Ramasamy, S | 1 |
| Jin, H | 1 |
| Teng, Y | 1 |
| Zhang, X | 1 |
| Yang, C | 2 |
| Xu, M | 2 |
| Yang, L | 1 |
| Zhang, Y | 4 |
| Qu, H | 1 |
| Zhou, Y | 1 |
| Wang, Y | 1 |
| Zhang, D | 4 |
| Yang, X | 1 |
| Cohen, SP | 1 |
| Kapoor, SG | 1 |
| Rathmell, JP | 1 |
| Sanada, T | 1 |
| Kohase, H | 1 |
| Makino, K | 1 |
| Umino, M | 1 |
| Zhang, GW | 3 |
| Yang, CX | 3 |
| Gao, HR | 2 |
| Jiao, RS | 3 |
| Zhang, H | 3 |
| Liang, Y | 3 |
| Xu, MY | 4 |
| Gao, HE | 1 |
| Hsieh, GC | 1 |
| Honore, P | 1 |
| Pai, M | 1 |
| Wensink, EJ | 1 |
| Chandran, P | 1 |
| Salyers, AK | 1 |
| Wetter, JM | 1 |
| Zhao, C | 1 |
| Liu, H | 1 |
| Decker, MW | 1 |
| Esbenshade, TA | 1 |
| Cowart, MD | 1 |
| Brioni, JD | 1 |
| Yang, DX | 1 |
| Zhai, Y | 1 |
| Wehnert, Y | 1 |
| Müller, B | 1 |
| Larsen, B | 1 |
| Kohn, D | 1 |
| SHABANAH, EH | 1 |
| TOTH, A | 1 |
| MAUGHAN, GB | 1 |
| Waldron, JB | 1 |
| Reid, AR | 2 |
| Sawynok, J | 4 |
| Kim, SK | 1 |
| Min, BI | 1 |
| Kim, JH | 1 |
| Hwang, BG | 1 |
| Yoo, GY | 1 |
| Park, DS | 1 |
| Na, HS | 3 |
| Lane, BR | 1 |
| Lane, BZ | 1 |
| Ausmundson, SJ | 1 |
| Butler, RS | 1 |
| Zippe, CD | 1 |
| Jones, JS | 1 |
| Lakin, MM | 1 |
| Shamloul, R | 1 |
| Atteya, A | 1 |
| Elnashaar, A | 1 |
| Gadallah, A | 1 |
| Zohdy, W | 1 |
| Abdelsalam, W | 1 |
| Mizuno, J | 1 |
| Ann, Y | 1 |
| Kawamura, G | 1 |
| Asahara, M | 1 |
| Sekiyama, H | 1 |
| Arita, H | 1 |
| Hanaoka, K | 2 |
| Phillips, WJ | 1 |
| Tollefson, B | 1 |
| Johnson, A | 1 |
| Abell, T | 1 |
| Lerant, A | 1 |
| Jin, XD | 1 |
| Guan, YZ | 1 |
| Zhang, SJ | 1 |
| Yue, WJ | 1 |
| Yaksh, TL | 2 |
| Reddy, SV | 1 |
| Sagen, J | 11 |
| Winker, MA | 1 |
| Proudfit, HK | 6 |
| Clementi, G | 1 |
| Prato, A | 1 |
| Conforto, G | 1 |
| Scapagnini, U | 1 |
| Carstens, E | 3 |
| Zimmermann, M | 2 |
| Doak, GJ | 1 |
| Siegan, JB | 2 |
| Ide, Y | 1 |
| Tagami, M | 1 |
| Nagase, M | 1 |
| Numata, K | 1 |
| Yamamura, H | 1 |
| Dellemijn, PL | 1 |
| Fields, HL | 2 |
| Allen, RR | 1 |
| McKay, WR | 1 |
| Rowbotham, MC | 2 |
| Kolhekar, R | 1 |
| Meller, ST | 2 |
| Gebhart, GF | 5 |
| Hama, AT | 1 |
| Verdugo, RJ | 1 |
| Campero, M | 1 |
| Ochoa, JL | 1 |
| Xie, YK | 1 |
| Xiao, WH | 1 |
| Rochford, J | 2 |
| Dawes, P | 2 |
| Kim, SH | 1 |
| Kwangsup, S | 1 |
| Jin, MC | 1 |
| Stewart, J | 1 |
| Moriel, EZ | 1 |
| Rajfer, J | 1 |
| Shir, Y | 1 |
| Cameron, LB | 1 |
| Raja, SN | 4 |
| Bourke, DL | 1 |
| Wang, H | 2 |
| Turnquist, JL | 1 |
| Meleka, S | 1 |
| Campbell, JN | 3 |
| Liu, M | 1 |
| Max, MB | 1 |
| Parada, S | 1 |
| Rowan, JS | 1 |
| Bennett, GJ | 1 |
| Shibahara, N | 1 |
| Matsuda, H | 1 |
| Umeno, K | 1 |
| Shimada, Y | 1 |
| Itoh, T | 1 |
| Terasawa, K | 1 |
| Ossipov, MH | 1 |
| Lopez, Y | 1 |
| Bian, D | 1 |
| Nichols, ML | 1 |
| Porreca, F | 1 |
| Zhang, C | 2 |
| Yang, SW | 1 |
| Guo, YG | 1 |
| Qiao, JT | 5 |
| Dafny, N | 4 |
| Kinnman, E | 1 |
| Nygårds, EB | 1 |
| Hansson, P | 1 |
| Koley, J | 1 |
| Basak, AK | 1 |
| Das, M | 1 |
| Sinha, S | 1 |
| Koley, B | 1 |
| Kindgen-Milles, D | 1 |
| Holthusen, H | 1 |
| Breivik, H | 1 |
| Tomai, F | 1 |
| Crea, F | 1 |
| Gaspardone, A | 1 |
| Versaci, F | 1 |
| Ghini, AS | 1 |
| De Paulis, R | 1 |
| Chiariello, L | 1 |
| Gioffrè, PA | 1 |
| Liu, RJ | 2 |
| Wang, R | 1 |
| Nie, H | 1 |
| Zhang, RX | 2 |
| McCleane, GJ | 1 |
| Lee, DH | 1 |
| Chung, K | 1 |
| Chung, JM | 1 |
| Schott, GD | 1 |
| Kim, HJ | 1 |
| Sung, B | 1 |
| Hong, SK | 1 |
| Engel, JD | 1 |
| McVary, KT | 1 |
| Ortega-Alvaro, A | 1 |
| Chover-Gonzalez, AJ | 1 |
| Lai-Kuen, R | 1 |
| Mico, JA | 1 |
| Gibert-Rahola, J | 1 |
| Fournié-Zaluski, MC | 1 |
| Roques, BP | 1 |
| Maldonado, R | 1 |
| Arnér, S | 2 |
| Zhao, Y | 1 |
| Kang, YM | 1 |
| Miao, FJ | 1 |
| Levine, JD | 2 |
| Aikawa, N | 1 |
| Ohmori, K | 1 |
| Baniel, J | 1 |
| Israilov, S | 1 |
| Engelstein, D | 1 |
| Shmueli, J | 1 |
| Segenreich, E | 1 |
| Livne, PM | 1 |
| Ali, Z | 1 |
| Wesselmann, U | 1 |
| Fuchs, PN | 1 |
| Meyer, RA | 1 |
| Kuroda, R | 1 |
| Kawao, N | 1 |
| Yoshimura, H | 1 |
| Umeda, W | 1 |
| Takemura, M | 1 |
| Shigenaga, Y | 1 |
| Kawabata, A | 1 |
| Ahn, DK | 1 |
| Kim, KH | 1 |
| Ju, JS | 1 |
| Kwon, S | 1 |
| Park, JS | 1 |
| Rainsford, KD | 1 |
| Galer, BS | 1 |
| Miller, KV | 1 |
| Walton, A | 1 |
| Bauer, MB | 1 |
| Yu, XM | 1 |
| Hua, M | 1 |
| Mense, S | 1 |
| Reid, A | 2 |
| Papir-Kricheli, D | 1 |
| Gilon, C | 1 |
| Chorev, M | 1 |
| Selinger, Z | 1 |
| Devor, M | 1 |
| Li, YJ | 1 |
| Xie, YF | 1 |
| Treede, RD | 1 |
| Davis, KD | 1 |
| Zhuo, M | 2 |
| Monasky, MS | 1 |
| Zinsmeister, AR | 1 |
| Stevens, CW | 1 |
| Miller, JF | 1 |
| Isbrucker, R | 1 |
| Pappas, GD | 2 |
| Wang, YJ | 1 |
| Wang, SK | 1 |
| Keogh, EJ | 1 |
| Watters, GR | 1 |
| Earle, CM | 1 |
| Carati, CJ | 1 |
| Wisniewski, ZS | 1 |
| Tulloch, GS | 1 |
| Lord, DJ | 1 |
| Nakamura, A | 1 |
| Sugao, T | 1 |
| Yamaue, K | 1 |
| Kobatake, M | 1 |
| Shiomi, H | 1 |
| Aanonsen, LM | 1 |
| Wilcox, GL | 1 |
| Taiwo, YO | 1 |
| Ren, K | 1 |
| Randich, A | 1 |
| Hough, LB | 1 |
| Glick, SD | 1 |
| Su, K | 1 |
| Janss, AJ | 1 |
| Chiang, CY | 1 |
| Fujiwara, R | 1 |
| Orita, K | 1 |
| Pretel, S | 1 |
| Guinan, MJ | 1 |
| Girdley, FM | 1 |
| Bruskewitz, RC | 1 |
| Feyzi, J | 1 |
| Graversen, PH | 1 |
| Gasser, TC | 1 |
| Roberts, WJ | 1 |
| Foglesong, ME | 1 |
| Sandkühler, J | 1 |
| Perlow, MJ | 1 |
| Guidobono, F | 1 |
| Netti, C | 1 |
| Sibilia, V | 1 |
| Olgiati, VR | 1 |
| Pecile, A | 1 |
| Simmonds, JP | 1 |
| Lister, J | 1 |
| Luck, RJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Analgesic Effects of Perioperative Propranolol Administration for Spine Surgery[NCT04421209] | Phase 2 | 0 participants (Actual) | Interventional | 2020-12-31 | Withdrawn (stopped due to No funding source) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for phentolamine and Pain
| Article | Year |
|---|---|
Intravenous infusion tests have limited utility for selecting long-term drug therapy in patients with chronic pain: a systematic review.
Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Local; Chr | 2009 |
14 trials available for phentolamine and Pain
| Article | Year |
|---|---|
[Sympathetically maintained pain (SMP): phentolamine test vs sympathetic nerve blockade. Comparison of two diagnostic methods].
Topics: Adrenergic alpha-Antagonists; Adult; Autonomic Nerve Block; Causalgia; Complex Regional Pain Syndrom | 2002 |
Intracavernous sodium nitroprusside (SNP) versus papaverine/phentolamine in erectile dysfunction: a comparative study of short-term efficacy and side-effects.
Topics: Adrenergic alpha-Antagonists; Adult; Drug Therapy, Combination; Erectile Dysfunction; Humans; Inject | 2005 |
Phentolamine sympathetic block in painful polyneuropathies. II. Further questioning of the concept of 'sympathetically maintained pain'.
Topics: Adult; Aged; Autonomic Nerve Block; Double-Blind Method; Female; Humans; Male; Middle Aged; Nerve Bl | 1994 |
Sodium bicarbonate alleviates penile pain induced by intracavernous injections for erectile dysfunction.
Topics: Adult; Aged; Alprostadil; Bicarbonates; Double-Blind Method; Drug Combinations; Erectile Dysfunction | 1993 |
Monitoring adequacy of alpha-adrenoceptor blockade following systemic phentolamine administration.
Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Aged; Chronic Disease; Dose-Response Relationship, | 1996 |
The sympathetic nervous system contributes to capsaicin-evoked mechanical allodynia but not pinprick hyperalgesia in humans.
Topics: Capsaicin; Cross-Over Studies; Double-Blind Method; Humans; Hyperalgesia; Injections, Intradermal; P | 1996 |
Peripheral alpha-adrenoreceptors are involved in the development of capsaicin induced ongoing and stimulus evoked pain in humans.
Topics: Adrenergic alpha-Antagonists; Adult; Arm; Capsaicin; Female; Humans; Injections, Intradermal; Inject | 1997 |
Nociception from blood vessels is independent of the sympathetic nervous system under physiological conditions in humans.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Electric Stimulation; Hand; Humans; Infusio | 1997 |
Phentolamine prevents adaptation to ischemia during coronary angioplasty: role of alpha-adrenergic receptors in ischemic preconditioning.
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Angioplasty, Balloon, Coronary; Blood Flow Velocity; Coro | 1997 |
Transurethral alprostadil as therapy for patients who withdrew from or failed prior intracavernous injection therapy.
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Alprostadil; | 1998 |
Three-year outcome of a progressive treatment program for erectile dysfunction with intracavernous injections of vasoactive drugs.
Topics: Adult; Aged; Aged, 80 and over; Alprostadil; Drug Therapy, Combination; Erectile Dysfunction; Follow | 2000 |
Intradermal injection of norepinephrine evokes pain in patients with sympathetically maintained pain.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Complex Regional Pain Syndromes; Fem | 2000 |
Systemic alpha-adrenergic blockade with phentolamine: a diagnostic test for sympathetically maintained pain.
Topics: Adult; Bupivacaine; Chronic Disease; Dose-Response Relationship, Drug; Ganglia, Sympathetic; Hemodyn | 1991 |
Treatment of impotence by intrapenile injections. A comparison of papaverine versus papaverine and phentolamine: a double-blind, crossover trial.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Erectile Dysfunction; | 1989 |
87 other studies available for phentolamine and Pain
| Article | Year |
|---|---|
Anti-inflammatory effects of propranolol in the temporomandibular joint of female rats and its contribution to antinociceptive action.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analgesics; Animals; Anti-Inflammatory Ag | 2018 |
Phentolamine Reverses Epinephrine-Enhanced Skin Antinociception of Dibucaine in Rats.
Topics: Adrenergic alpha-Antagonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Area Under Curve; | 2019 |
Injection anxiety and pain in men using intracavernosal injection therapy after radical pelvic surgery.
Topics: Aged; Alprostadil; Anxiety; Drug Combinations; Erectile Dysfunction; Humans; Injections; Male; Middl | 2013 |
Involvement of opioidergic and serotonergic systems in the analgesic activity of Cissus quadrangularis L. stem extract in mice.
Topics: Analgesics; Animals; Cissus; Dose-Response Relationship, Drug; Fenclonine; Mice; Naloxone; Pain; Phe | 2015 |
Noradrenergic mechanism involved in the nociceptive modulation of hippocampal CA3 region of normal rats.
Topics: Adrenergic alpha-Antagonists; Animals; CA3 Region, Hippocampal; Electric Stimulation; Male; Neurons; | 2014 |
The involvement of norepinephrine in pain modulation in the nucleus accumbens of morphine-dependent rats.
Topics: Adrenergic alpha-Antagonists; Animals; Electric Stimulation; Evoked Potentials; Male; Morphine Depen | 2015 |
Effects of alpha-adrenergic agonists on pain modulation in diffuse noxious inhibitory control.
Topics: Adrenergic alpha-Agonists; Adrenergic Antagonists; Animals; Dexmedetomidine; Electromyography; Injec | 2009 |
Microinjection of different doses of norepinephrine into the caudate putamen produces opposing effects in rats.
Topics: Animals; Dose-Response Relationship, Drug; Hot Temperature; Microinjections; Norepinephrine; Pain; P | 2010 |
Noradrenergic mechanism involved in the nociceptive modulation of nociceptive-related neurons in the caudate putamen.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Animals; Electric Stimulation; Electrophysiological | 2010 |
Antinociceptive effects of histamine H3 receptor antagonist in the preclinical models of pain in rats and the involvement of central noradrenergic systems.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Benzazepines; Dose-Response Relationshi | 2010 |
Effects of norepinephrine on the electrical activities of pain-related neurons in the rat nucleus accumbens.
Topics: Animals; Electric Stimulation; Female; Male; Microelectrodes; Neurons; Norepinephrine; Nucleus Accum | 2011 |
THE ROLE OF THE AUTONOMIC NERVOUS SYSTEM IN UTERINE MOTILITY AND BLOOD FLOW. 3. VISUAL, AUDITORY, AND PAINFUL STIMULI AND THEIR INFLUENCE ON UTERINE MOTILITY BEFORE AND AFTER CORD SECTION AND THE EFFECT OF SYMPATHOLYTIC DRUGS IN RESTORING NORMAL ACTIVITY.
Topics: Animals; Autonomic Nervous System; Blood Circulation; Dogs; Epinephrine; Ergot Alkaloids; Female; Hu | 1965 |
Amitriptyline produces multiple influences on the peripheral enhancement of nociception by P2X receptors.
Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Amitriptyline; Analgesics, Non-Narcotic; Anima | 2004 |
Individual differences in the sensitivity of cold allodynia to phentolamine in neuropathic rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-A | 2005 |
Use of a visual analog scale to assess pain of injection with intracavernous injection therapy.
Topics: Adult; Aged; Alprostadil; Diabetes Mellitus; Drug Administration Routes; Humans; Injections; Male; M | 2005 |
[Postponed or canceled drug challenge tests and side effects of the test drug--a report of four cases].
Topics: Adult; Aged; Arthritis, Rheumatoid; Chronic Disease; Female; Fibromyalgia; Humans; Intervertebral Di | 2006 |
Relief of acute pain in chronic idiopathic gastroparesis with intravenous phentolamine.
Topics: Abdominal Pain; Acute Disease; Adult; Female; Gastroparesis; Humans; Infusions, Intravenous; Pain; P | 2006 |
[Phentolamine antagonizes the effects of norepinephrine on the activity of pain-related neurons in the parafascicular nucleus of morphine-dependent rats].
Topics: Animals; Drug Antagonism; Electrophysiology; Intralaminar Thalamic Nuclei; Neurons; Norepinephrine; | 2008 |
Studies in the primate on the analgetic effects associated with intrathecal actions of opiates, alpha-adrenergic agonists and baclofen.
Topics: Adrenergic alpha-Agonists; Analgesia; Animals; Avoidance Learning; Baclofen; Behavior, Animal; Cats; | 1981 |
Hypoalgesia induced by the local injection of phentolamine in the nucleus raphe magnus: blockade by depletion of spinal cord monoamines.
Topics: Animals; Brain Stem; Male; Norepinephrine; Pain; Perception; Phentolamine; Raphe Nuclei; Rats; Rats, | 1983 |
Effect of intrathecally administered noradrenergic antagonists on nociception in the rat.
Topics: Animals; Brain Mapping; Brain Stem; Dioxanes; Efferent Pathways; Injections, Spinal; Male; Norepinep | 1984 |
Role of serotonin in the analgesic activity of calcitonin.
Topics: Analgesics; Animals; Calcitonin; Drug Antagonism; Male; Methysergide; Norepinephrine; Pain; Phentola | 1984 |
Hypoalgesia induced by blockade of noradrenergic projections to the raphe magnus: reversal by blockade of noradrenergic projections to the spinal cord.
Topics: Animals; Brain Stem; Male; Naloxone; Norepinephrine; Pain; Phentolamine; Raphe Nuclei; Rats; Sensory | 1981 |
The opiate antagonist naloxone does not consistently block inhibition of spinal nociceptive transmission produced by stimulation in lateral midbrain reticular formation of the cat.
Topics: Afferent Pathways; Animals; Cats; Endorphins; Mesencephalon; Naloxone; Pain; Phentolamine; Propranol | 1980 |
Caffeine antinociception in the rat hot-plate and formalin tests and locomotor stimulation: involvement of noradrenergic mechanisms.
Topics: Adrenergic alpha-Antagonists; Animals; Caffeine; Dioxanes; Drug Synergism; Formaldehyde; Hot Tempera | 1995 |
Attenuation of NMDA-induced spinal hypersensitivity by adrenal medullary transplants.
Topics: Adrenal Medulla; Animals; Dose-Response Relationship, Drug; Hot Temperature; Hyperalgesia; Injection | 1995 |
[Effects of hyperventilation upon the spinal pain modulating system (third report)].
Topics: Action Potentials; Animals; Anterior Horn Cells; Cats; Evoked Potentials; Hyperventilation; Pain; Ph | 1994 |
The interpretation of pain relief and sensory changes following sympathetic blockade.
Topics: Adult; Aged; Autonomic Nervous System Diseases; Body Temperature; Female; Humans; Male; Middle Aged; | 1994 |
Characterization of the role of spinal N-methyl-D-aspartate receptors in thermal nociception in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Behavior, Animal; Cold Temperature; Hot Temperature; | 1993 |
Alleviation of neuropathic pain symptoms by xenogeneic chromaffin cell grafts in the spinal subarachnoid space.
Topics: Adrenal Medulla; Animals; Body Temperature; Cattle; Chromaffin System; Cold Temperature; Hindlimb; M | 1994 |
Inhibitory effect of anisodamine on the neuropathic hyperalgesia following peripheral nerve injury (II).
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Electrophysiology; Hyperalgesia; Nerve Fibers; Pai | 1993 |
Effect of naloxone on the habituation of novelty-induced hypoalgesia: the collateral inhibition hypothesis revisited.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Clonidine | 1993 |
Effects of sympathectomy on a rat model of peripheral neuropathy.
Topics: Animals; Disease Models, Animal; Guanethidine; Hot Temperature; Male; Pain; Pain Measurement; Periph | 1993 |
Naloxone potentiation of novelty-induced hypoalgesia: characterization of the alpha-noradrenergic receptor subtype.
Topics: Animals; Clonidine; Drug Synergism; Habituation, Psychophysiologic; Male; Naloxone; Pain; Phentolami | 1993 |
The safety of intravenous phentolamine administration in patients with neuropathic pain.
Topics: Age Factors; Female; Hemodynamics; Humans; Infusions, Intravenous; Male; Nervous System Diseases; Pa | 1993 |
Attenuation of pain-related hyperventilation in adjuvant arthritic rats with adrenal medullary transplants in the spinal subarachnoid space.
Topics: Adrenal Medulla; Adrenergic alpha-Antagonists; Animals; Arthritis, Experimental; Catecholamines; Chr | 1995 |
The responses of skin blood flow, mean arterial pressure and R-R interval induced by cold stimulation with cold wind and ice water.
Topics: Adolescent; Adrenergic alpha-Antagonists; Adrenergic Fibers; Adult; Blood Pressure; Body Temperature | 1996 |
Synergistic antinociceptive interactions of morphine and clonidine in rats with nerve-ligation injury.
Topics: Adrenergic alpha-Agonists; Analgesics; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Sy | 1997 |
Locus coeruleus stimulation modulates the nociceptive response in parafascicular neurons: an analysis of descending and ascending pathways.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Denervation; Evoked Potentials; Fe | 1997 |
Attenuation of formalin pain responses in the rat by adrenal medullary transplants in the spinal subarachnoid space.
Topics: Adrenal Medulla; Adrenergic alpha-Antagonists; Animals; Foot; Formaldehyde; Injections; Male; Naloxo | 1997 |
Rectal response of cardiac origin in the cat: involvement of nitric oxide and acetylcholine.
Topics: Acetylcholine; Afferent Pathways; Animals; Arginine; Atropine; Blood Pressure; Cats; Coronary Vessel | 1997 |
Chronic pain and the sympathetic nervous system.
Topics: Autonomic Nervous System Diseases; Causalgia; Chronic Disease; Clinical Trials as Topic; Double-Blin | 1997 |
Effects of intrathecal monoamine antagonists on the nociceptive c-Fos expression in a lesioned rat spinal cord.
Topics: Adrenergic alpha-Antagonists; Animals; Cyproheptadine; Drug Interactions; Female; Immunohistochemist | 1997 |
Intravenous phentolamine mesylate alleviates the pain of pancreatic carcinoma.
Topics: Adult; Analgesics, Non-Narcotic; Humans; Infusions, Intravenous; Male; Pain; Pancreatic Neoplasms; P | 1997 |
Strain differences in adrenergic sensitivity of neuropathic pain behaviors in an experimental rat model.
Topics: Animals; Forelimb; Male; Pain; Pain Threshold; Phentolamine; Rats; Rats, Inbred Lew; Rats, Inbred St | 1997 |
Interrupting the sympathetic outflow in causalgia and reflex sympathetic dystrophy.
Topics: Autonomic Nerve Block; Causalgia; Guanethidine; Humans; Meta-Analysis as Topic; Pain; Phentolamine; | 1998 |
Amount of sympathetic sprouting in the dorsal root ganglia is not correlated to the level of sympathetic dependence of neuropathic pain in a rat model.
Topics: Adrenergic alpha-Antagonists; Animals; Ganglia, Spinal; Histocytochemistry; Male; Pain; Pain Measure | 1998 |
Antinociception produced by the peptidase inhibitor, RB 101, in rats with adrenal medullary transplant into the spinal cord.
Topics: Adrenal Medulla; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Disulfides; Injections | 1998 |
Pain analysis in prediction of treatment outcome.
Topics: Adenosine; Analgesics; Analgesics, Opioid; Anesthetics, Local; Dose-Response Relationship, Drug; Dru | 1998 |
Interrelations of opioids with monoamines in descending inhibition of nociceptive transmission at the spinal level: an immunocytochemical study.
Topics: Adrenergic alpha-Antagonists; Animals; Biogenic Monoamines; Cyproheptadine; Immunohistochemistry; In | 1999 |
Endogenous adenosine involved in the mediation of spinal antinociception produced by stimulating locus coeruleus.
Topics: Adenosine; Aminophylline; Animals; Electric Stimulation; Female; Locus Coeruleus; Male; Pain; Phento | 1999 |
Neural and endocrine mechanisms mediating noxious stimulus-induced inhibition of bradykinin plasma extravasation in the rat.
Topics: Adrenal Glands; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Bradykinin; Caps | 1999 |
Effect of zaldaride maleate, an antidiarrheal compound, on visceral pain reflex induced by small intestinal distention in anesthetized rats.
Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Animals, Newborn; Antidiarrheals; Atropine; Benzi | 1999 |
Secondary somatosensory cortex stimulation facilitates the antinociceptive effect of the NO synthase inhibitor through suppression of spinal nociceptive neurons in the rat.
Topics: Adrenergic alpha-Antagonists; Animals; Electric Stimulation; Enzyme Inhibitors; Indazoles; Injection | 2001 |
Microinjection of arginine vasopressin into the central nucleus of amygdala suppressed nociceptive jaw opening reflex in freely moving rats.
Topics: Adrenergic alpha-Antagonists; Amygdala; Animals; Arginine Vasopressin; Dose-Response Relationship, D | 2001 |
The role of aspirin in gastric ulceration . Some factors involved in the development of gastric mucosal damage induced by aspirin in rats exposed to various stress conditions.
Topics: Animals; Arthritis, Experimental; Aspirin; Atropine Derivatives; Bethanechol Compounds; Cold Tempera | 1978 |
Treatment of inflammatory, neuropathic and sympathetically maintained pain in a patient with Sjögren's syndrome.
Topics: Action Potentials; Adult; Female; Humans; Inflammation; Lidocaine; Nerve Block; Pain; Pain Managemen | 1992 |
Bradykinin modulation of a spinal nociceptive reflex in the rat.
Topics: Analysis of Variance; Animals; Blood Pressure; Bradykinin; Capsaicin; Dinoprostone; Dose-Response Re | 1992 |
The effects of intracerebroventricular injection of naloxone, phentolamine and methysergide on the transmission of nociceptive signals in rat dorsal horn neurons with convergent cutaneous-deep input.
Topics: Animals; Endorphins; Female; Injections, Intraventricular; Male; Methysergide; Muscles; Naloxone; Ne | 1991 |
Noradrenergic and purinergic involvement in spinal antinociception by 5-hydroxytryptamine and 2-methyl-5-hydroxytryptamine.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Injections, Spinal; Male; Oxidopamine; Pain; | 1991 |
Neurochemical mediators of the behavioural effects of receptor-selective substance P agonists administered intrathecally in the rat.
Topics: Animals; Injections, Spinal; Male; Methysergide; Morphine; Muscles; Naloxone; Pain; Peptide Fragment | 1990 |
Effects of intrathecal monoamine antagonists and naloxone on the descending inhibition of the spinal transmission of noxious input in rats: study with a new experimental model.
Topics: Animals; Female; Injections, Spinal; Male; Methysergide; Naloxone; Neurons; Pain; Peroneal Nerve; Ph | 1991 |
Spinal serotonin receptors mediate descending facilitation of a nociceptive reflex from the nuclei reticularis gigantocellularis and gigantocellularis pars alpha in the rat.
Topics: Amidines; Analysis of Variance; Animals; Atropine; Blood Pressure; Brain; Electric Stimulation; Hear | 1991 |
Intravenous phentolamine test: diagnostic and prognostic use in reflex sympathetic dystrophy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Female; Guanethidine; Humans; Injections, Intrave | 1991 |
Interaction of intrathecal morphine and ST-91 on antinociception in the rat: dose-response analysis, antagonism and clearance.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; | 1990 |
Antagonism of stimulation-produced antinociception from ventrolateral pontine sites by intrathecal administration of alpha-adrenergic antagonists and naloxone.
Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Dopamine beta-Hydroxylase; Electric Stimulation; Fe | 1990 |
Adenosine mediates calcium-induced antinociception and potentiation of noradrenergic antinociception in the spinal cord.
Topics: 5,7-Dihydroxytryptamine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium; Drug Synerg | 1990 |
Adrenal medullary implants in the rat spinal cord reduce nociception in a chronic pain model.
Topics: Adrenal Medulla; Animals; Arthritis, Experimental; Catecholamines; Chronic Disease; Endorphins; Graf | 1990 |
Effects of phentolamine and propranolol on the changes of pain threshold and contents of MEK and LEK in rat brain after EA.
Topics: Animals; Brain; Electroacupuncture; Enkephalin, Leucine; Enkephalin, Methionine; Male; Pain; Phentol | 1989 |
Involvement of spinal noradrenergic system in the mechanism of an antinociceptive effect of delta-sleep-inducing peptide (DSIP).
Topics: Adrenergic Fibers; Analgesia; Animals; Delta Sleep-Inducing Peptide; Male; Mice; Pain; Phentolamine; | 1989 |
Nociceptive action of excitatory amino acids in the mouse: effects of spinally administered opioids, phencyclidine and sigma agonists.
Topics: Animals; Aspartic Acid; Enkephalins; Hot Temperature; Kainic Acid; Male; Mice; N-Methylaspartate; Na | 1987 |
Prostaglandins inhibit endogenous pain control mechanisms by blocking transmission at spinal noradrenergic synapses.
Topics: Animals; Aspirin; Dinoprostone; Dose-Response Relationship, Drug; Indomethacin; Injections, Spinal; | 1988 |
Vagal afferent modulation of a nociceptive reflex in rats: involvement of spinal opioid and monoamine receptors.
Topics: Afferent Pathways; Animals; Blood Pressure; Electric Stimulation; Hot Temperature; Injections, Spina | 1988 |
A role for histamine and histamine H2-receptors in non-opiate footshock-induced analgesia.
Topics: Animals; Cimetidine; Electroshock; Haloperidol; Histamine; Histamine H2 Antagonists; Male; Naloxone; | 1985 |
Spinal monoaminergic receptors mediate the antinociception produced by glutamate in the medullary lateral reticular nucleus.
Topics: Animals; Electric Stimulation; Glutamates; Glutamic Acid; Hot Temperature; Male; Methysergide; Micro | 1987 |
Evidence for the involvement of a descending cholinergic pathway in systemic morphine analgesia.
Topics: Analgesia; Animals; Atropine; Cholinergic Fibers; Efferent Pathways; Injections, Intraperitoneal; In | 1989 |
The enhancement of the immune response by pain stimulation in mice. I. The enhancement effect on PFC production via sympathetic nervous system in vivo and in vitro.
Topics: Animals; Antibody Formation; Epinephrine; Hexamethonium Compounds; Immunoglobulin M; Male; Mice; Osm | 1987 |
Inhibition of the responses of cat dorsal horn neurons to noxious skin heating by stimulation in medial or lateral medullary reticular formation.
Topics: Action Potentials; Afferent Pathways; Animals; Cats; Electric Stimulation; Female; Hot Temperature; | 1988 |
Intracavernous self-injection for impotence: a long-term therapeutic option? Experience in 78 patients.
Topics: Consumer Behavior; Drug Combinations; Erectile Dysfunction; Humans; Male; Middle Aged; Pain; Papaver | 1988 |
Spinal recordings suggest that wide-dynamic-range neurons mediate sympathetically maintained pain.
Topics: Adaptation, Physiological; Adrenergic Fibers; Animals; Cats; Electric Stimulation; Female; Lidocaine | 1988 |
Neuronal effects of controlled superfusion of the spinal cord with monoaminergic receptor antagonists in the cat.
Topics: Animals; Cats; Methysergide; Naloxone; Nociceptors; Pain; Perfusion; Phentolamine; Spinal Cord | 1988 |
Release of endogenous monoamines into spinal cord superfusates following the microinjection of phentolamine into the nucleus raphe magnus.
Topics: Animals; Efferent Pathways; Microinjections; Norepinephrine; Pain; Phentolamine; Raphe Nuclei; Rats; | 1987 |
Alterations in nociception following adrenal medullary transplants into the rat periaqueductal gray.
Topics: Adrenal Medulla; Adrenergic Fibers; Animals; Endorphins; Female; Male; Naloxone; Nicotine; Pain; Per | 1987 |
Alterations in nociception following lesions of the A5 catecholamine nucleus.
Topics: Adrenergic Fibers; Animals; Brain Mapping; Female; Injections, Spinal; Methysergide; Norepinephrine; | 1986 |
Role of catecholamines in calcitonin-induced analgesia.
Topics: Analgesics; Animals; Atenolol; Calcitonin; Catecholamines; Hydroxydopamines; Injections, Intraventri | 1985 |
Letter: Localisation of phaeochromocytoma.
Topics: Adrenal Gland Neoplasms; Diagnostic Techniques, Surgical; Humans; Injections, Intravenous; Laparotom | 1974 |
[Antihypertensive agents].
Topics: Acetazolamide; Antihypertensive Agents; Bis-Trimethylammonium Compounds; Bretylium Compounds; Chlori | 1972 |