phentolamine has been researched along with Neuritis in 2 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
Neuritis: A general term indicating inflammation of a peripheral or cranial nerve. Clinical manifestation may include PAIN; PARESTHESIAS; PARESIS; or HYPESTHESIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Because PM had not been approved previously for submucosal administration, 2 Good Laboratory Practices (GLP) studies in dogs designed to investigate systemic toxicity and the local effects of single and repeated dosing of OraVerse on the inferior alveolar nerve and branches of the superior alveolar nerve and adjacent soft tissues after local administration were conducted." | 1.35 | Local and systemic toxicity of intraoral submucosal injections of phentolamine mesylate (OraVerse). ( Rutherford, B; Thake, D; Zeller, JR, 2009) |
| "The effect of NE on mechanical hyperalgesia was mediated by both peripheral alpha(1)- and alpha(2)-adrenoceptors." | 1.32 | Peripheral norepinephrine exacerbates neuritis-induced hyperalgesia. ( Baik, E; Chung, JM; Chung, K, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rutherford, B | 1 |
| Zeller, JR | 1 |
| Thake, D | 1 |
| Baik, E | 1 |
| Chung, JM | 1 |
| Chung, K | 1 |
2 other studies available for phentolamine and Neuritis
| Article | Year |
|---|---|
Local and systemic toxicity of intraoral submucosal injections of phentolamine mesylate (OraVerse).
Topics: Adrenergic alpha-Antagonists; Anesthetics, Local; Animals; Cranial Nerve Diseases; Dogs; Hematocrit; | 2009 |
Peripheral norepinephrine exacerbates neuritis-induced hyperalgesia.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Freund's Adjuvan | 2003 |