phentolamine has been researched along with Neuralgia in 8 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Therapeutic potential of agomelatine on neuropathic pain was suppressed with α-methyl-para-tyrosine methyl ester (an inhibitor of catecholamine synthesis), phentolamine (a nonselective α-adrenoceptor antagonist), and propranolol (a nonselective β-adrenoceptor antagonist) administrations." | 1.43 | Effect of subacute agomelatine treatment on painful diabetic neuropathy: involvement of catecholaminergic mechanisms. ( Aydın, TH; Can, ÖD; Demir Özkay, Ü; Turan, N, 2016) |
| "Along with the severity of cancer, the nature of pain becomes changed to neuropathic pain, which is resistant to morphine or NSAIDS." | 1.32 | [Pain and QOL--morphine-tolerance and morphine-resistant neuropathic pain]. ( Ueda, H, 2003) |
| "Mechanical hyperalgesia was evaluated by determining the frequency of withdrawal to von Frey monofilaments applied to the hind paws." | 1.31 | Nerve injury-induced mechanical but not thermal hyperalgesia is attenuated in neurokinin-1 receptor knockout mice. ( DeVries, C; Lee, H; Mansikka, H; Raja, SN; Sheth, RN; Winchurch, R, 2000) |
| "The pain and hyperalgesia persisted during a phentolamine infusion, which produced a sympathetic blockade." | 1.31 | Neuropathic pain after C7 spinal nerve transection in man. ( Ali, Z; Belzberg, AJ; Meyer, RA, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Nakatsuka, K | 1 |
| Matsuoka, Y | 1 |
| Kurita, M | 1 |
| Wang, R | 1 |
| Tsuboi, C | 1 |
| Sue, N | 1 |
| Kaku, R | 1 |
| Morimatsu, H | 1 |
| Ogon, I | 1 |
| Takebayashi, T | 1 |
| Miyakawa, T | 1 |
| Iwase, T | 1 |
| Tanimoto, K | 1 |
| Terashima, Y | 1 |
| Jimbo, S | 1 |
| Kobayashi, T | 1 |
| Tohse, N | 1 |
| Yamashita, T | 1 |
| Aydın, TH | 1 |
| Can, ÖD | 1 |
| Demir Özkay, Ü | 1 |
| Turan, N | 1 |
| Barchini, J | 1 |
| Tchachaghian, S | 1 |
| Shamaa, F | 1 |
| Jabbur, SJ | 1 |
| Meyerson, BA | 1 |
| Song, Z | 1 |
| Linderoth, B | 1 |
| Saadé, NE | 1 |
| Ueda, H | 1 |
| Mansikka, H | 1 |
| Sheth, RN | 1 |
| DeVries, C | 1 |
| Lee, H | 1 |
| Winchurch, R | 1 |
| Raja, SN | 1 |
| Sekiyama, H | 1 |
| Hanaoka, K | 1 |
| Ali, Z | 1 |
| Meyer, RA | 1 |
| Belzberg, AJ | 1 |
1 review available for phentolamine and Neuralgia
| Article | Year |
|---|---|
[Diagnosis and assessment of pain].
Topics: Barbiturates; Humans; Ketamine; Lidocaine; Morphine; Neuralgia; Pain Measurement; Phentolamine | 2001 |
7 other studies available for phentolamine and Neuralgia
| Article | Year |
|---|---|
Intrathecal Administration of the α1 Adrenergic Antagonist Phentolamine Upregulates Spinal GLT-1 and Improves Mirror Image Pain in SNI Model Rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Disease Models, Animal; Neuralgia; Phentolamine; R | 2022 |
Attenuation of pain behaviour by local administration of alpha-2 adrenoceptor antagonists to dorsal root ganglia in a rat radiculopathy model.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-A | 2016 |
Effect of subacute agomelatine treatment on painful diabetic neuropathy: involvement of catecholaminergic mechanisms.
Topics: Acetamides; Animals; Blood Glucose; Catecholamines; Diabetes Mellitus, Experimental; Diabetic Neurop | 2016 |
Spinal segmental and supraspinal mechanisms underlying the pain-relieving effects of spinal cord stimulation: an experimental study in a rat model of neuropathy.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Baclofen; | 2012 |
[Pain and QOL--morphine-tolerance and morphine-resistant neuropathic pain].
Topics: Adrenergic alpha-Antagonists; Capsaicin; Drug Resistance; Drug Therapy, Combination; Drug Tolerance; | 2003 |
Nerve injury-induced mechanical but not thermal hyperalgesia is attenuated in neurokinin-1 receptor knockout mice.
Topics: Animals; Behavior, Animal; Cold Temperature; Hot Temperature; Hyperalgesia; Mice; Mice, Inbred BALB | 2000 |
Neuropathic pain after C7 spinal nerve transection in man.
Topics: Adrenergic alpha-Antagonists; Adult; Brachial Plexus; Child; Cold Temperature; Female; Hot Temperatu | 2002 |