phentolamine has been researched along with Necrosis in 24 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A case of pheochromocytoma with spontaneous remission after recovery from shock induced by the phentolamine test is presented." | 7.67 | Pheochromocytoma with remission following phentolamine-induced shock. ( Akaza, H; Asakage, H; Kawabe, K; Koiso, K; Mori, C; Niijima, T; Suzuki, T; Ueno, A, 1984) |
| "Phentolamine rescue was not performed." | 5.46 | Digital Necrosis After Lidocaine and Epinephrine Injection in the Flexor Tendon Sheath Without Phentolamine Rescue. ( Carr, N; Gray, J; Lalonde, DH; Zhang, JX, 2017) |
| "Labetalol was found to be less effective in preventing tissue necrosis." | 5.28 | Treatment of peripheral ischemia secondary to lidocaine containing epinephrine. ( Aycock, BG; Hawtof, DB; Moody, SB, 1989) |
| "A case of ruptured pheochromocytoma is presented, the pathophysiology discussed, and the literature reviewed." | 5.26 | Hemorrhagic necrosis of pheochromocytoma associated with phentolamine administration. ( Cleveland, HC; Faraci, RP; Foster, JF; Scott, HW; Van Way, CW, 1976) |
| "A case of pheochromocytoma with spontaneous remission after recovery from shock induced by the phentolamine test is presented." | 3.67 | Pheochromocytoma with remission following phentolamine-induced shock. ( Akaza, H; Asakage, H; Kawabe, K; Koiso, K; Mori, C; Niijima, T; Suzuki, T; Ueno, A, 1984) |
| " There is relatively poor clinician knowledge surrounding adrenaline reversal and a lack of easily accessible information available about dosing and drug location within the hospital." | 1.91 | Adrenaline auto-injector injuries: Practical considerations in emergency management in a tertiary hand surgery unit. ( Ellis, K; McCaughran, PW; Mosahebi, A; Nikkhah, D; Southall, C; Zargaran, D, 2023) |
| "Phentolamine rescue was not performed." | 1.46 | Digital Necrosis After Lidocaine and Epinephrine Injection in the Flexor Tendon Sheath Without Phentolamine Rescue. ( Carr, N; Gray, J; Lalonde, DH; Zhang, JX, 2017) |
| "Labetalol was found to be less effective in preventing tissue necrosis." | 1.28 | Treatment of peripheral ischemia secondary to lidocaine containing epinephrine. ( Aycock, BG; Hawtof, DB; Moody, SB, 1989) |
| "Yohimbine pretreatment reduced cocaine-induced latent lethality by 50%, but did not alter the time to lethality." | 1.27 | Antagonism of cocaine-induced hepatotoxicity by the alpha adrenergic antagonists phentolamine and yohimbine. ( Harbison, RD; James, RC; Roberts, SM; Schiefer, MA, 1987) |
| "5 ml/kg dosage of bromobenzene." | 1.27 | Antagonism of bromobenzene-induced hepatotoxicity by the alpha-adrenergic blocking agents, phentolamine and idazoxan. ( Bucci, TJ; Gandy, J; Harbison, RD; James, RC; Kerger, BD; Roberts, SM, 1988) |
| "A case of ruptured pheochromocytoma is presented, the pathophysiology discussed, and the literature reviewed." | 1.26 | Hemorrhagic necrosis of pheochromocytoma associated with phentolamine administration. ( Cleveland, HC; Faraci, RP; Foster, JF; Scott, HW; Van Way, CW, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (83.33) | 18.7374 |
| 1990's | 2 (8.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (4.17) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| McCaughran, PW | 1 |
| Ellis, K | 1 |
| Southall, C | 1 |
| Zargaran, D | 1 |
| Nikkhah, D | 1 |
| Mosahebi, A | 1 |
| Zhang, JX | 1 |
| Gray, J | 1 |
| Lalonde, DH | 1 |
| Carr, N | 1 |
| ZUCKER, G | 2 |
| EISINGER, RP | 1 |
| DILLAHA, CJ | 1 |
| JANSEN, GT | 1 |
| HONEYCUTT, WM | 1 |
| HAYDEN, CR | 1 |
| Suzuki, T | 1 |
| Mori, C | 1 |
| Asakage, H | 1 |
| Akaza, H | 1 |
| Kawabe, K | 1 |
| Ueno, A | 1 |
| Koiso, K | 1 |
| Niijima, T | 1 |
| Bloksma, N | 1 |
| Hofhuis, FM | 1 |
| Willers, JM | 1 |
| Sylaidis, P | 1 |
| Logan, A | 1 |
| Wexler, MR | 1 |
| Kalisman, M | 1 |
| Yeschua, R | 1 |
| Neuman, Z | 1 |
| Neil-Dwyer, G | 1 |
| Walter, P | 1 |
| Cruickshank, JM | 1 |
| Doshi, B | 1 |
| O'Gorman, P | 1 |
| Falk, RH | 1 |
| Casscells, W | 1 |
| Van Way, CW | 1 |
| Faraci, RP | 1 |
| Cleveland, HC | 1 |
| Foster, JF | 1 |
| Scott, HW | 1 |
| Bove, EL | 1 |
| Argenta, LC | 1 |
| Cimmino, VM | 1 |
| Brown, JW | 1 |
| Nishiyama, RH | 1 |
| Kirsh, MM | 1 |
| Forrest, CR | 1 |
| Pang, CY | 1 |
| Zhong, AG | 1 |
| Neligan, PC | 1 |
| Aycock, BG | 1 |
| Hawtof, DB | 1 |
| Moody, SB | 1 |
| James, RC | 2 |
| Schiefer, MA | 1 |
| Roberts, SM | 2 |
| Harbison, RD | 2 |
| Kerger, BD | 1 |
| Gandy, J | 1 |
| Bucci, TJ | 1 |
| Hershey, FB | 1 |
| Aulenbacher, CE | 1 |
| Palmer, B | 1 |
| Vander Ark, GD | 1 |
| Norton, LW | 1 |
| Pomerantz, M | 1 |
| Mikulicich, GF | 1 |
| Oester, TY | 1 |
| Yarom, R | 1 |
| Braun, K | 1 |
| Delaney, JP | 1 |
| Paritzky, AZ | 1 |
| Weeks, PM | 1 |
1 trial available for phentolamine and Necrosis
| Article | Year |
|---|---|
Effect of propranolol and phentolamine on myocardial necrosis after subarachnoid haemorrhage.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Female; Humans; Male; Mid | 1978 |
23 other studies available for phentolamine and Necrosis
| Article | Year |
|---|---|
Adrenaline auto-injector injuries: Practical considerations in emergency management in a tertiary hand surgery unit.
Topics: Anaphylaxis; Epinephrine; Hand; Humans; Injections, Intramuscular; Necrosis; Phentolamine | 2023 |
Digital Necrosis After Lidocaine and Epinephrine Injection in the Flexor Tendon Sheath Without Phentolamine Rescue.
Topics: Amputation, Surgical; Anesthetics, Local; Epinephrine; Female; Finger Injuries; Humans; Lidocaine; M | 2017 |
Use of phentolamine to prevent necrosis due to levarterenol.
Topics: Humans; Necrosis; Norepinephrine; Phentolamine; Sympatholytics | 1957 |
Prevention of levarterenol necrosis in rabbits by use of levarterenol-phentolamine mixtures.
Topics: Animals; Biomedical Research; Lagomorpha; Necrosis; Norepinephrine; Phentolamine; Rabbits; Sympathol | 1960 |
NORTH AMERICAN LOXOSCELISM. NECROTIC BITE OF THE BROWN RECLUSE SPIDER.
Topics: Animals; Arkansas; Brown Recluse Spider; Diagnosis; Gangrene; Histamine H1 Antagonists; Humans; Hydr | 1964 |
Pheochromocytoma with remission following phentolamine-induced shock.
Topics: Adrenal Gland Neoplasms; Adult; Female; Humans; Necrosis; Phentolamine; Pheochromocytoma; Remission, | 1984 |
Effect of adrenoceptor blockade on hemorrhagic necrosis of meth A sarcomata induced by endotoxin or tumor necrosis serum.
Topics: Animals; Dose-Response Relationship, Drug; Endotoxins; Female; Fibrosarcoma; Immune Sera; Mice; Necr | 1982 |
Local injection of phentolamine to treat digital ischaemic necrosis in Raynaud's syndrome.
Topics: Aged; Autonomic Nerve Block; Humans; Ischemia; Male; Necrosis; Phentolamine; Raynaud Disease; Sympat | 1997 |
The effect of phenoxybenzamine, phentolamine and 6-hydroxydopamine on skin flap survival in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Arteriovenous Shunt, Surgical; E | 1975 |
Effects of drugs on myocardial necrosis after subarachnoid haemorrhage.
Topics: Humans; Myocardium; Necrosis; Phentolamine; Propranolol; Subarachnoid Hemorrhage | 1978 |
Hemorrhagic necrosis of pheochromocytoma associated with phentolamine administration.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aged; Female; Hemorrhage; Humans; Hypertension; Necr | 1976 |
The morphologic effects of simultaneous infusion of levarterenol and phentolamine on the canine myocardium.
Topics: Animals; Blood Pressure; Cardiac Output; Dogs; Drug Interactions; Heart; Hemorrhage; Necrosis; Norep | 1975 |
Role of noradrenaline in the pathogenesis of skin flap ischemic necrosis in the pig.
Topics: Animals; Ischemia; Necrosis; Norepinephrine; Phenoxybenzamine; Phentolamine; Propranolol; Skin; Surg | 1990 |
Treatment of peripheral ischemia secondary to lidocaine containing epinephrine.
Topics: Animals; Epinephrine; Foot; Ischemia; Labetalol; Lidocaine; Models, Biological; Necrosis; Phentolami | 1989 |
Antagonism of cocaine-induced hepatotoxicity by the alpha adrenergic antagonists phentolamine and yohimbine.
Topics: Adrenergic alpha-Antagonists; Animals; Biomechanical Phenomena; Cocaine; Female; Glutathione; Liver; | 1987 |
Antagonism of bromobenzene-induced hepatotoxicity by the alpha-adrenergic blocking agents, phentolamine and idazoxan.
Topics: Adrenergic alpha-Antagonists; Alanine Transaminase; Animals; Bromobenzenes; Chemical and Drug Induce | 1988 |
Surgical treatment of brown spider bites.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anti-Bacterial Agents; Bites and Stings; Child, Pr | 1969 |
The influence of stress on the survival of experimental skin flaps. A study on rats.
Topics: Adrenergic alpha-Antagonists; Animals; Capillaries; Catecholamines; Immobilization; Male; Necrosis; | 1972 |
The effects of brain stem compression on the heart.
Topics: Animals; Arrhythmias, Cardiac; Atropine; Blood Pressure; Bradycardia; Brain Injuries; Brain Stem; Ca | 1974 |
The inhibition of the epinephrine--thyroxin induced arteriosclerosis by phentolamine.
Topics: Animals; Aorta; Arteriosclerosis; Cardiomyopathies; Epinephrine; Injections, Intravenous; Injections | 1970 |
Cardiovascular effects of scorpion venom, morphological changes in the myocardium.
Topics: Animals; Antivenins; Coronary Vessels; Dibenzylchlorethamine; Dogs; Heart; Heart Diseases; Hemorrhag | 1970 |
Necrosis of a pheochromocytoma with shock.
Topics: Adrenal Gland Neoplasms; Adult; Catecholamines; Female; Humans; Hypertension; Hypotension; Necrosis; | 1969 |
Ischemia of the hand secondary to levarterenol bitartrate extravasation. Methods of management.
Topics: Female; Hand; Humans; Ischemia; Male; Necrosis; Norepinephrine; Phentolamine; Skin Manifestations; S | 1966 |