phentolamine has been researched along with Myotonic Dystrophy in 2 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
Myotonic Dystrophy: Neuromuscular disorder characterized by PROGRESSIVE MUSCULAR ATROPHY; MYOTONIA, and various multisystem atrophies. Mild INTELLECTUAL DISABILITY may also occur. Abnormal TRINUCLEOTIDE REPEAT EXPANSION in the 3' UNTRANSLATED REGIONS of DMPK PROTEIN gene is associated with Myotonic Dystrophy 1. DNA REPEAT EXPANSION of zinc finger protein-9 gene intron is associated with Myotonic Dystrophy 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The pharmacological responses of vascular adrenergic receptors to intravenously administered epinephrine, phentolamine, and propranolol were assessed by measuring muscle blood flow (MBF) changes in the tibialis anterior muscle using the xenon 133 clearance technique and were compared in 8 normal subjects and 11 patients with myotonic dystrophy." | 3.66 | Vascular adrenergic receptor responses in skeletal muscle in myotonic dystrophy. ( Mastaglia, FL; Mechler, F, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mechler, F | 1 |
| Mastaglia, FL | 1 |
| Castaigne, P | 1 |
| Bousser, MG | 1 |
| Lecrubier, C | 1 |
| Conard, J | 1 |
| Samama, M | 1 |
2 other studies available for phentolamine and Myotonic Dystrophy
| Article | Year |
|---|---|
Vascular adrenergic receptor responses in skeletal muscle in myotonic dystrophy.
Topics: Adolescent; Adult; Blood Vessels; Epinephrine; Female; Humans; Male; Middle Aged; Muscles; Myotonic | 1981 |
[Increase in platelet sensitivity to adrenaline in Steinert's disease].
Topics: Adult; Blood Platelet Disorders; Epinephrine; Female; Humans; Male; Middle Aged; Myotonic Dystrophy; | 1977 |