phentolamine has been researched along with Muscle Relaxation in 90 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These results suggest potentially effective combined therapies of sildenafil and intraurethral or intracavernosal prostaglandin-E1, intracavernosal forskolin or VIP, or oral phentolamine for patients with erectile dysfunction who have no success after monotherapy with these agents." | 3.71 | Synergistic effects of sildenafil on relaxation of rabbit and rat cavernosal smooth muscles when combined with various vasoactive agents. ( Jun, IO; Kim, SC; Lee, MY; Oh, MM; Seo, KK, 2001) |
| "In vitro and in vivo studies were performed to determine the potential use of tamsulosin (TAM) versus phentolamine (PHE) for intracavernosal injection (ICI) therapy when mixed with papaverine (PAP) and/or prostagladin E1 (PGE1) or with vasoactive intestinal polypeptide (VIP) for the treatment of erectile dysfunction." | 3.70 | Comparison of the synergistic effects of tamsulosin versus phentolamine on penile erection: in vitro and in vivo studies. ( Kim, SC; Lee, MY; Lee, SK; Seo, KK; Song, ES, 1999) |
| "In order to study the inhibitory mechanism by which sodium azide eliminates smooth muscle contraction in vivo and in vitro, gastrointestinal motility was monitored via chronically implanted force transducers in the stomach and duodenum of conscious dogs." | 3.69 | Sodium azide induces relaxation of the canine gastric body by activating a guanylate cyclase-dependent pathway. ( Itoh, Z; Mizumoto, A; Sakai, T; Sano, I; Tamura, T, 1997) |
| "Pre-treatment with aldosterone also significantly extended the mean (SEM) time required to reach 50% relaxation of a noradrenaline-induced contraction, of 9." | 1.35 | Effect of aldosterone on isolated human penile corpus cavernosum tissue. ( Anzai, H; Kagawa, J; Kanayama, HO; Kawanishi, Y; Kishimoto, T; Kojima, K; Muguruma, H; Numata, A; Sugiyama, H; Tanimoto, S; Yamanaka, M, 2008) |
| "When isosorbide dinitrate (ISDN, 1 mM) was applied during isometric measurement, 18." | 1.31 | The effects of vasodilators on the relaxation of guinea-pig aorta during acute recoil. ( Hirai, M; Iino, S; Kondo, T; Takeshita, K; Tanaka, T, 2002) |
| "Pretreatment with phentolamine (10(-5) M) (alpha-antagonist) converted the contraction induced by NE to relaxation in coronary rings precontracted with ONO11113 (thromboxane A2 derivative)." | 1.29 | Participation of alpha 1- and beta 1-adrenoceptors in norepinephrine-induced contraction and relaxation of isolated equine coronary artery in vitro. ( Kabeyama, A; Nishio, A; Obi, T, 1994) |
| "Pretreatment with atropine, phentolamine, and diphenhydramine antagonized the motilin- and bombesin-induced contraction." | 1.29 | Effects of various peptides on isolated rabbit lower esophageal sphincter. ( Kohjitani, A; Obara, H; Okada, S; Shirakawa, J, 1996) |
| " HA-1004 shifted the dose-response curve for CaCl2 to the right in a competitive manner in depolarized rabbit renal arterial strips." | 1.27 | Relaxation of vascular smooth muscle by HA-1004, an inhibitor of cyclic nucleotide-dependent protein kinase. ( Hidaka, H; Inagaki, M; Ishikawa, T; Watanabe, M, 1985) |
| " Isolated rings (circular preparations) obtained from rat thoracic aortae responded to increasing concentrations of NE with dose-dependent tonic enhancement, not significantly affected by the presence of indomethacin (10(-6)M); whereas, preincubation with phentolamine (10(-6)M), yohimbine (10(-7)M) or prazosin (10(-8)M), shifted significantly to the right points of the positive inotropic dose-response curve for NE." | 1.27 | Possible prostacyclin involvement on disparate tonic responses to "in vitro" norepinephrine in circular and in longitudinal preparations from rat thoracic aorta. ( Chaud, M; Franchi, AM; Gimeno, AL; Gimeno, MA, 1987) |
| " For each agent tested in this study, dose-response curves were established." | 1.27 | Micturition in the unanesthetized rat: spinal vs. peripheral pharmacology of the adrenergic system. ( Durant, PA; Lucas, PC; Yaksh, TL, 1988) |
| " No long-lasting effect of the alpha-adrenergic blocker was apparent since the response to norepinephrine was not altered following a 1-hour washout of phentolamine after the isoproterenol dose-response curve." | 1.27 | Phentolamine and rat aortic smooth muscle responsiveness to potassium chloride, isoproterenol and norepinephrine. ( Katovich, MJ; Soltis, EE, 1985) |
| "Trapidil could inhibit these effects of 5-HT or phenylephrine." | 1.26 | Analysis of relaxant effects of trapidil in isolated dog coronary artery. ( Fukai, R; Higuchi, M; Hirata, A; Kondoh, G; Sakanashi, M; Yoshikawa, Y, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 42 (46.67) | 18.7374 |
| 1990's | 31 (34.44) | 18.2507 |
| 2000's | 16 (17.78) | 29.6817 |
| 2010's | 1 (1.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, J | 1 |
| Ip, PS | 1 |
| Yeung, JH | 1 |
| Che, CT | 1 |
| Tanaka, T | 1 |
| Iino, S | 1 |
| Takeshita, K | 1 |
| Kondo, T | 1 |
| Hirai, M | 1 |
| Palea, S | 1 |
| Barras, M | 1 |
| Akimoto, Y | 1 |
| Horinouchi, T | 4 |
| Tanaka, Y | 2 |
| Koike, K | 4 |
| Sharabi, FM | 1 |
| Daabees, TT | 1 |
| El-Metwally, MA | 1 |
| Senbel, AM | 1 |
| Gontero, P | 1 |
| Sriprasad, S | 1 |
| Wilkins, CJ | 1 |
| Donaldson, N | 1 |
| Muir, GH | 1 |
| Sidhu, PS | 1 |
| Hanouz, JL | 1 |
| Persehaye, E | 1 |
| Zhu, L | 1 |
| Lammens, S | 1 |
| Lepage, O | 1 |
| Massetti, M | 1 |
| Babatasi, G | 1 |
| Khayat, A | 1 |
| Bricard, H | 1 |
| Gérard, JL | 1 |
| Pescatori, ES | 2 |
| Morgia, G | 1 |
| Pirozzi-Farina, F | 1 |
| Farina, FP | 1 |
| Yamashita, Y | 1 |
| Michikawa, H | 1 |
| Muguruma, H | 1 |
| Kawanishi, Y | 1 |
| Sugiyama, H | 1 |
| Kagawa, J | 1 |
| Tanimoto, S | 1 |
| Yamanaka, M | 1 |
| Kojima, K | 1 |
| Anzai, H | 1 |
| Numata, A | 1 |
| Kishimoto, T | 1 |
| Kanayama, HO | 1 |
| Metsä-Ketelä, T | 1 |
| Ishikawa, Y | 1 |
| Takahashi, T | 2 |
| Yamamura, T | 2 |
| Mikkelsen, E | 2 |
| Sakr, AM | 1 |
| Jespersen, LT | 1 |
| Nakahata, N | 1 |
| Hayashi, A | 1 |
| Suzuki, T | 2 |
| Kimura, I | 1 |
| Kimura, M | 2 |
| Lal, B | 1 |
| Dohadwalla, AN | 1 |
| Dadkar, NK | 1 |
| D'Sa, A | 1 |
| de Souza, NJ | 1 |
| Klarskov, P | 1 |
| Gerstenberg, TC | 1 |
| Ramirez, D | 1 |
| Hald, T | 1 |
| Doidge, JM | 1 |
| Satchell, DG | 1 |
| Janssens, WJ | 1 |
| Verhaeghe, RH | 1 |
| Sakanashi, M | 2 |
| Yoshikawa, Y | 1 |
| Kondoh, G | 1 |
| Fukai, R | 1 |
| Hirata, A | 1 |
| Higuchi, M | 1 |
| Hatano, Y | 1 |
| Kohli, JD | 1 |
| Goldberg, LI | 1 |
| Fried, J | 1 |
| Papasova, M | 1 |
| Mizhorkova, Z | 1 |
| Yamahara, NS | 1 |
| Tanaka, M | 1 |
| Imaizumi, Y | 1 |
| Watanabe, M | 2 |
| Takayanagi, I | 1 |
| Muramatsu, M | 1 |
| Ohki, S | 1 |
| Lee, YS | 1 |
| Kim, CH | 1 |
| Yun-Choi, HS | 1 |
| Chang, KC | 1 |
| Lonovics, J | 1 |
| Jakab, I | 1 |
| Szilvássy, J | 1 |
| Szilvássy, Z | 1 |
| Obi, T | 1 |
| Kabeyama, A | 1 |
| Nishio, A | 2 |
| Tamaoki, J | 1 |
| Yamauchi, F | 1 |
| Chiyotani, A | 1 |
| Yamawaki, I | 1 |
| Takeuchi, S | 1 |
| Konno, K | 1 |
| Miyamoto, A | 1 |
| Ito, K | 1 |
| Bramuglia, GF | 1 |
| Kazanietz, MG | 1 |
| Pezman, E | 1 |
| Enero, MA | 1 |
| Kohjitani, A | 1 |
| Shirakawa, J | 1 |
| Okada, S | 1 |
| Obara, H | 1 |
| Koley, J | 1 |
| Basak, AK | 1 |
| Das, M | 1 |
| Sinha, S | 1 |
| Koley, B | 1 |
| Sano, I | 1 |
| Mizumoto, A | 1 |
| Sakai, T | 1 |
| Tamura, T | 1 |
| Itoh, Z | 1 |
| Bayguinov, O | 1 |
| Sanders, KM | 1 |
| Arimitsu, M | 1 |
| Mitsui-Saito, M | 1 |
| Sato, K | 1 |
| Ozaki, H | 1 |
| Koga, Y | 1 |
| Karaki, H | 1 |
| Chiu, JH | 1 |
| Lui, WY | 1 |
| Chen, YL | 1 |
| Hong, CY | 1 |
| Igawa, Y | 1 |
| Yamazaki, Y | 1 |
| Takeda, H | 1 |
| Akahane, M | 1 |
| Ajisawa, Y | 1 |
| Yoneyama, T | 1 |
| Nishizawa, O | 1 |
| Traish, A | 1 |
| Gupta, S | 1 |
| Gallant, C | 1 |
| Huang, YH | 1 |
| Goldstein, I | 2 |
| Wang, Y | 1 |
| Bukoski, RD | 1 |
| De Luca, A | 1 |
| Li, CG | 1 |
| Rand, MJ | 1 |
| Adeyemi, OO | 1 |
| Okpo, SO | 1 |
| Young-Nwafor, CC | 1 |
| Kim, SC | 2 |
| Seo, KK | 2 |
| Lee, SK | 1 |
| Song, ES | 1 |
| Lee, MY | 2 |
| Moncada Iribarren, I | 1 |
| Sáenz de Tejada, I | 2 |
| Kim, NN | 1 |
| Moreland, RB | 1 |
| Traish, AM | 1 |
| Silingardi, V | 1 |
| Galeazzi, GM | 1 |
| Rigatelli, M | 1 |
| Ranzi, A | 1 |
| Artibani, W | 1 |
| Tunçtan, B | 1 |
| Altuğ, S | 1 |
| Uludağ, O | 1 |
| Abacioğlu, N | 1 |
| Yamamoto, Y | 1 |
| Angulo, J | 1 |
| Cuevas, P | 1 |
| Fernández, A | 1 |
| Gabancho, S | 1 |
| Vemulapalli, S | 1 |
| Kurowski, S | 1 |
| Jun, IO | 1 |
| Oh, MM | 1 |
| Takasaki, K | 1 |
| Tang, LC | 1 |
| Urabe, M | 1 |
| Hoang, ND | 1 |
| Brecht, K | 1 |
| Sjöstrand, NO | 1 |
| Klinge, E | 1 |
| Ueda, S | 1 |
| Ikegami, K | 1 |
| Yonemura, KI | 1 |
| Andersson, KE | 1 |
| Jahnberg, T | 1 |
| Abrahamsson, H | 1 |
| Jansson, G | 1 |
| Martinson, J | 1 |
| Behar, J | 1 |
| Biancani, P | 1 |
| Banerjee, S | 1 |
| Mitra, C | 1 |
| Mukherjee, AK | 1 |
| Toda, N | 2 |
| Baba, H | 1 |
| Tanobe, Y | 1 |
| Okamura, T | 2 |
| Lefebvre, RA | 1 |
| Horacek, J | 1 |
| Bang, L | 1 |
| Nielsen-Kudsk, JE | 1 |
| Taneike, T | 1 |
| Miyazaki, H | 1 |
| Nakamura, H | 1 |
| Ohga, A | 2 |
| Watanabe, K | 1 |
| Hayashi, Y | 1 |
| Ikeda, K | 1 |
| Ohnishi, H | 1 |
| Consolini, A | 1 |
| Grand, C | 1 |
| Masuda, Y | 1 |
| Arakawa, C | 1 |
| Yamashita, T | 1 |
| Miyajima, M | 1 |
| Shigenobu, K | 1 |
| Kasuya, Y | 1 |
| Tanaka, S | 1 |
| Grous, M | 1 |
| Ormsbee, H | 1 |
| Barnette, M | 1 |
| Matsufuji, H | 1 |
| Kortesova, NI | 1 |
| Kimova, VS | 1 |
| Bagaev, VA | 1 |
| Papasova, MP | 1 |
| Giuliani, S | 1 |
| Maggi, CA | 1 |
| Rovero, P | 1 |
| Meli, A | 1 |
| Murray, MA | 1 |
| Boyle, JP | 1 |
| Small, RC | 1 |
| De Ponti, F | 1 |
| Azpiroz, F | 2 |
| Malagelada, JR | 2 |
| Tanaka, DT | 1 |
| Grunstein, MM | 1 |
| McPherson, GA | 1 |
| Angus, JA | 1 |
| Molderings, GJ | 1 |
| Engel, G | 1 |
| Roth, E | 1 |
| Göthert, M | 1 |
| Mostaghim, R | 1 |
| Thomas, G | 1 |
| Ramwell, PW | 1 |
| Kantoh, M | 1 |
| Kusunoki, M | 1 |
| Utsunomiya, J | 1 |
| Rapoport, RM | 1 |
| Schwartz, K | 1 |
| Murad, F | 1 |
| Ishikawa, T | 1 |
| Inagaki, M | 1 |
| Hidaka, H | 1 |
| Komori, S | 1 |
| Ohashi, H | 1 |
| Chaud, M | 1 |
| Franchi, AM | 1 |
| Gimeno, MA | 1 |
| Gimeno, AL | 1 |
| Ito, S | 1 |
| Ohta, T | 1 |
| Durant, PA | 1 |
| Lucas, PC | 1 |
| Yaksh, TL | 1 |
| Koch, TR | 1 |
| Carney, JA | 1 |
| Go, VL | 1 |
| Szurszewski, JH | 1 |
| Miyazaki, M | 1 |
| Greenberg, B | 1 |
| Rhoden, K | 1 |
| Barnes, PJ | 1 |
| Barthó, L | 1 |
| Pethö, G | 1 |
| Antal, A | 1 |
| Holzer, P | 1 |
| Szolcsányi, J | 1 |
| Lucchelli, A | 1 |
| Boselli, C | 1 |
| Chiari, MC | 1 |
| Grana, E | 1 |
| Soltis, EE | 1 |
| Katovich, MJ | 1 |
3 reviews available for phentolamine and Muscle Relaxation
| Article | Year |
|---|---|
Diagnosing erectile dysfunction: instruments for the study of smooth muscle relaxation.
Topics: Erectile Dysfunction; Hemodynamics; Humans; Male; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; P | 2005 |
Pharmacological treatment of erectile dysfunction.
Topics: Adrenergic alpha-Antagonists; Alprostadil; Apomorphine; Dopamine Agonists; Erectile Dysfunction; Hum | 1999 |
Reactivity of isolated bovine facial vessels to electric stimulation and to drugs.
Topics: Acetylcholine; Animals; Bretylium Tosylate; Catecholamines; Cattle; Cocaine; Cyclic AMP; Electric St | 1979 |
1 trial available for phentolamine and Muscle Relaxation
| Article | Year |
|---|---|
Audiovisual sexual stimulation by virtual glasses is effective in inducing complete cavernosal smooth muscle relaxation: a pharmacocavernosometric study.
Topics: Adult; Aged; Audiovisual Aids; Erectile Dysfunction; Eyeglasses; Humans; Male; Middle Aged; Muscle R | 2000 |
86 other studies available for phentolamine and Muscle Relaxation
| Article | Year |
|---|---|
Inhibitory effect of schisandrin on spontaneous contraction of isolated rat colon.
Topics: Adrenergic Antagonists; Animals; Atropine; Benzyl Compounds; Colon, Ascending; Cyclic GMP; Cycloocta | 2011 |
The effects of vasodilators on the relaxation of guinea-pig aorta during acute recoil.
Topics: Adrenergic alpha-Antagonists; Amlodipine; Angioplasty, Balloon, Coronary; Animals; Aorta, Thoracic; | 2002 |
Comparison of the relaxant effects of alfuzosin, phentolamine and sildenafil on rabbit isolated corpus cavernosum.
Topics: Adrenergic alpha-Antagonists; Animals; Erectile Dysfunction; Male; Muscle Relaxation; Penile Erectio | 2003 |
The beta3-adrenoceptor-mediated relaxation induced by dopamine in guinea pig taenia caecum.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atenolol; Benzazepines; Butoxami | 2003 |
Comparative effects of sildenafil, phentolamine, yohimbine and L-arginine on the rabbit corpus cavernosum.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arginine; Atropine; Cyclic Nucleotide Phosphodiesteras | 2004 |
Phentolamine re-dosing during penile dynamic colour Doppler ultrasound: a practical method to abolish a false diagnosis of venous leakage in patients with erectile dysfunction.
Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Aged; Alprostadil; Blood Pressure; Diagnostic Error | 2004 |
The inotropic and lusitropic effects of ketamine in isolated human atrial myocardium: the effect of adrenoceptor blockade.
Topics: Adrenergic alpha-Antagonists; Adrenergic Antagonists; Adrenergic beta-Antagonists; Anesthetics, Diss | 2004 |
Pharmacological characterization of the beta-adrenoceptor that mediates the relaxant response to noradrenaline in guinea-pig tracheal smooth muscle.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; A | 2007 |
Effect of aldosterone on isolated human penile corpus cavernosum tissue.
Topics: Adult; Aged; Aldosterone; Humans; In Vitro Techniques; Male; Middle Aged; Mineralocorticoid Receptor | 2008 |
Cyclic AMP-dependent and -independent effects of beta-adrenergic stimulation on the contraction-relaxation cycle of spontaneously beating rat atria.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Calcium; Cyclic AMP; Heart Atria; Io | 1982 |
[Action of adenosine 5'-triphosphate and effects of various purinergic receptor blocking agents on the movements of an isolated guinea pig gallbladder].
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Apamin; Atropine; Female; Gallbladder; | 1983 |
Studies on the effect of histamine in isolated human pulmonary arteries and veins.
Topics: Aged; Dimaprit; Female; Histamine; Humans; In Vitro Techniques; Male; Methylhistamines; Middle Aged; | 1984 |
Temperature dependence if beta-receptor mediated relaxation in rabbit intestine.
Topics: Animals; Cyclic AMP; Dihydroalprenolol; Female; In Vitro Techniques; Intestines; Isoproterenol; Male | 1982 |
Potassium induces relaxation and hyperpolarization of circular muscles but contraction of longitudinal muscles of pig duodenum.
Topics: Animals; Calcium; Duodenum; Electrophysiology; Female; In Vitro Techniques; Male; Membrane Potential | 1984 |
Trequinsin, a potent new antihypertensive vasodilator in the series of 2-(arylimino)-3-alkyl-9,10-dimethoxy-3,4,6,7-tetrahydro-2H-py rim ido [6,1-a]isoquinolin-4-ones.
Topics: Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Female; Guinea Pigs; Isoquinolines; | 1984 |
Non-cholinergic, non-adrenergic nerve mediated relaxation of trigone, bladder neck and urethral smooth muscle in vitro.
Topics: Animals; Atropine; Electric Stimulation; Female; Ketoprofen; Male; Muscle Contraction; Muscle Relaxa | 1983 |
Adrenergic and non-adrenergic inhibitory nerves in mammalian airways.
Topics: Acetylcholine; Animals; Bronchi; Electric Stimulation; Guanethidine; Guinea Pigs; Haplorhini; Humans | 1982 |
Effect of thrombin on isolated canine blood vessels.
Topics: Acetylcholine; Animals; Cattle; Dogs; Humans; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, | 1982 |
[Neural control of the intestines].
Topics: Adenosine Triphosphate; Animals; Autonomic Nervous System; Guinea Pigs; Intestines; Muscle Relaxatio | 1982 |
Analysis of relaxant effects of trapidil in isolated dog coronary artery.
Topics: Acetylcholine; Animals; Coronary Vessels; Dogs; Drug Interactions; Female; In Vitro Techniques; Isop | 1980 |
Relative contracting and relaxing potencies of a series of prostaglandins on isolated canine mesenteric artery strips.
Topics: Animals; Biological Assay; Dogs; Isoproterenol; Mesenteric Arteries; Muscle Contraction; Muscle Rela | 1981 |
Responses for smooth-muscle strips from the ileo-caecal region to transmural electrical stimulation.
Topics: Animals; Atropine; Cats; Cecum; Electric Stimulation; Ileum; In Vitro Techniques; Muscle Contraction | 1980 |
Pertussis toxin-sensitive muscarinic relaxation in the rat iris dilator muscle.
Topics: Acetylcholine; Alkaloids; Animals; Atropine; Diamines; Dose-Response Relationship, Drug; Furans; GTP | 1995 |
Involvement of beta 3-adrenoceptor in the relaxation response in guinea pig taenia caecum.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Binding, Competitive; Butoxamine; Cecum; Dose-Respon | 1994 |
Cardiovascular effect of a naphthylmethyl substituted tetrahydroisoquinoline, YS 49, in rat and rabbit.
Topics: Animals; Aorta; Blood Pressure; Female; Heart Atria; Heart Rate; In Vitro Techniques; Isoquinolines; | 1994 |
Regional differences in nitric oxide-mediated relaxation of the rabbit sphincter of Oddi.
Topics: Animals; Arginine; Atropine; Autonomic Nervous System; Electric Stimulation; In Vitro Techniques; Is | 1994 |
Participation of alpha 1- and beta 1-adrenoceptors in norepinephrine-induced contraction and relaxation of isolated equine coronary artery in vitro.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-1 Receptor Antagonists; Animals; Atenolol; | 1994 |
Atypical beta-adrenoceptor- (beta 3-adrenoceptor) mediated relaxation of canine isolated bronchial smooth muscle.
Topics: Acetylcholine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Bronchi; C | 1993 |
Characterization of beta-adrenoceptors in pig basilar artery from functional and radioligand binding studies.
Topics: Adrenergic beta-Antagonists; Animals; Basilar Artery; Dihydroalprenolol; Endothelium, Vascular; In V | 1993 |
Beta-adrenoceptor desensitization by/clenbuterol in rat uterus.
Topics: Adrenergic beta-Antagonists; Animals; Clenbuterol; Colforsin; Cyclic AMP; Estradiol; Female; In Vitr | 1993 |
Effects of various peptides on isolated rabbit lower esophageal sphincter.
Topics: Animals; Atropine; Bombesin; Calcitonin Gene-Related Peptide; Diphenhydramine; Dose-Response Relatio | 1996 |
Rectal response of cardiac origin in the cat: involvement of nitric oxide and acetylcholine.
Topics: Acetylcholine; Afferent Pathways; Animals; Arginine; Atropine; Blood Pressure; Cats; Coronary Vessel | 1997 |
Sodium azide induces relaxation of the canine gastric body by activating a guanylate cyclase-dependent pathway.
Topics: Adrenergic alpha-Antagonists; Animals; Cyclic GMP; Dogs; Electric Stimulation; Enzyme Inhibitors; Fe | 1997 |
Dissociation between electrical and mechanical responses to nitrergic stimulation in the canine gastric fundus.
Topics: Animals; Arginine; Atropine; Calcium; Cytosol; Dogs; Electric Stimulation; Female; Gastric Fundus; G | 1998 |
Mechanism of relaxant effect of clonidine in isolated bovine tracheal smooth muscle.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Cattle; Clonidine; Cyclic | 1998 |
Local somatothermal stimulation inhibits the motility of sphincter of Oddi in cats, rabbits and humans through nitrergic neural release of nitric oxide.
Topics: Animals; Arginine; Atropine; Benzodiazepinones; Body Temperature; Cats; Devazepide; Female; Hormone | 1998 |
Possible beta 3-adrenoceptor-mediated relaxation of the human detrusor.
Topics: Adrenergic Antagonists; Adrenergic beta-Agonists; Adult; Aged; Bupranolol; Dobutamine; Dose-Response | 1998 |
Phentolamine mesylate relaxes penile corpus cavernosum tissue by adrenergic and non-adrenergic mechanisms.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Cell-Free Sy | 1998 |
Use of acute phenolic denervation to show the neuronal dependence of Ca2+-induced relaxation of isolated arteries.
Topics: Acetylcholine; Animals; Calcium; Calcium-Binding Proteins; Dose-Response Relationship, Drug; Electri | 1999 |
Nitrergic and purinergic mechanisms and their interactions for relaxation of the rat internal anal sphincter.
Topics: Adrenergic alpha-Antagonists; Adrenergic Antagonists; Adrenergic beta-Antagonists; Anal Canal; Anima | 1999 |
The relaxant activity of the methanolic extract of Acanthus montanus on intestinal smooth muscles.
Topics: Animals; Colon; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Intestines; Isopro | 1999 |
Comparison of the synergistic effects of tamsulosin versus phentolamine on penile erection: in vitro and in vivo studies.
Topics: Adrenergic alpha-Antagonists; Alprostadil; Animals; Blood Pressure; Dogs; Drug Synergism; Erectile D | 1999 |
Alpha-adrenergic receptor blockade by phentolamine increases the efficacy of vasodilators in penile corpus cavernosum.
Topics: Adrenergic alpha-Antagonists; Alprostadil; Animals; Drug Interactions; Electric Stimulation; Humans; | 2000 |
Effects of econazole on receptor-operated and depolarization-induced contractions in rat isolated aorta.
Topics: Animals; Antifungal Agents; Aorta; Calcium; Calcium Channel Blockers; Calcium Channels; Dose-Respons | 2000 |
The beta3-adrenoceptor-mediated relaxation induced by epinephrine in guinea pig taenia caecum.
Topics: Animals; Bupranolol; Cecum; Cyclic AMP; Epinephrine; Guinea Pigs; In Vitro Techniques; Male; Muscle | 2000 |
Combination of phentolamine and L-arginine or sildenafil synergistically improves neurogenic relaxation of rabbit corpus cavernosum smooth muscle.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adrenergic alpha-Antagonists; Animals; Arginine; Drug Synergism | 2001 |
Phentolamine mesylate relaxes rabbit corpus cavernosum by a nonadrenergic, noncholinergic mechanism.
Topics: Adrenergic alpha-Antagonists; Animals; Cyclic GMP-Dependent Protein Kinases; Electric Stimulation; E | 2001 |
Synergistic effects of sildenafil on relaxation of rabbit and rat cavernosal smooth muscles when combined with various vasoactive agents.
Topics: Animals; Antihypertensive Agents; Cardiovascular Agents; Colforsin; Drug Synergism; Drug Therapy, Co | 2001 |
The beta-adrenergic responses in isolated splenic capsule area of several species of animals.
Topics: Animals; Cats; Dogs; Dose-Response Relationship, Drug; Epinephrine; Guinea Pigs; In Vitro Techniques | 1979 |
Principal mechanisms controlling penile retraction and protrusion in rabbits.
Topics: Animals; Arginine Vasopressin; Atropine; Electric Stimulation; Epinephrine; Male; Muscle Relaxation; | 1979 |
Effects of prostaglandin E1 on isolated dog renal artery.
Topics: Animals; Diltiazem; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Isoproteren | 1979 |
Contractile effects of prostaglandin F2alpha on isolated human peripheral arteries and veins.
Topics: Adult; Aged; Arteries; Calcium; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; | 1978 |
Gastric relaxatory response to feeding before and after vagotomy.
Topics: Animals; Atropine; Dogs; Food; Gastrointestinal Motility; Guanethidine; Muscle Contraction; Muscle R | 1977 |
Effect of cholecystokinin-octapeptide on lower esophageal sphincter.
Topics: Animals; Atropine; Autonomic Fibers, Postganglionic; Cats; Cholecystokinin; Dose-Response Relationsh | 1977 |
Smooth muscle relaxant properties and vasomotor actions of 2-amino-1-p-nitrophenylpropane-1,3-diol.
Topics: Animals; Antazoline; Anura; Aorta; Atropine; Calcium; Cats; Drug Interactions; Female; Guinea Pigs; | 1977 |
Mechanism of relaxation induced by K+ and nicotine in dog duodenal longitudinal muscle.
Topics: Adenosine Triphosphate; Animals; Apamin; Atropine; Bradykinin; Cations, Monovalent; Cyclic GMP; Dogs | 1992 |
Relaxant effects of BRL 38227 and pinacidil on the rat gastric fundus.
Topics: Animals; Benzopyrans; Cromakalim; Dose-Response Relationship, Drug; Female; Gastric Fundus; Glyburid | 1992 |
Smooth muscle relaxation and inhibition of responses to pinacidil and cromakalim induced by phentolamine in guinea-pig isolated trachea.
Topics: Animals; Benzopyrans; Carbachol; Cromakalim; Dinoprost; Female; Guanidines; Guinea Pigs; Histamine; | 1992 |
Autonomic innervation of the circular and longitudinal layers in swine myometrium.
Topics: Animals; Autonomic Nervous System; Carteolol; Catecholamines; Choline O-Acetyltransferase; Cholinest | 1991 |
[Effect of moxisylyte on the lower urinary tracts (2). Effect on the urethra in anesthetized dogs].
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Femal | 1991 |
[Effect of nifedipine on perfusion pressure changes produced by alpha 1 adrenergic agonists and depolarizing solution in rat hindlimbs].
Topics: Animals; Calcium; Dose-Response Relationship, Drug; Isotonic Solutions; Muscle Relaxation; Nifedipin | 1991 |
Potassium channel opening properties of a novel compound, NIP-121, cromakalim and nicorandil in rat aorta and portal vein.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Benzopyrans; Cromakalim; Glyburide; In Vitro Tech | 1991 |
Dimethylphenylpiperazinium (DMPP)-induced relaxation and elevation of cyclic GMP content in canine lower esophageal sphincter (LES).
Topics: Animals; Cyclic GMP; Dimethylphenylpiperazinium Iodide; Dogs; Electromagnetic Fields; Esophagogastri | 1990 |
[Responses of muscle strips from the internal anal sphincter in Hirschsprung's disease to drugs and electrical field stimulation].
Topics: Anal Canal; Animals; Child, Preschool; Dogs; Electric Stimulation; Female; Hirschsprung Disease; Hum | 1990 |
The mechanism of action of bombesin on cat lower esophageal sphincter.
Topics: Animals; Atropine; Bombesin; Cats; Electric Stimulation; Esophagogastric Junction; Muscle Relaxation | 1990 |
Neurokinins induce a relaxation of the rat duodenum "in vivo" by activating postganglionic sympathetic elements in prevertebral ganglia: involvement of an NK-2 type of neurokinin receptor.
Topics: Adrenalectomy; Animals; Duodenum; Guanethidine; Kassinin; Male; Muscle Contraction; Muscle Relaxatio | 1988 |
Cromakalim-induced relaxation of guinea-pig isolated trachealis: antagonism by glibenclamide and by phentolamine.
Topics: Animals; Benzopyrans; Cromakalim; Electrophysiology; Female; Glyburide; Guinea Pigs; In Vitro Techni | 1989 |
Relaxatory responses of canine proximal stomach to esophageal and duodenal distension. Importance of vagal pathways.
Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Deglutition; Dilatation; Dogs; Duodenum; Esop | 1989 |
Vasoactive effects of substance P on isolated rabbit pulmonary artery.
Topics: Animals; Atropine; Biomechanical Phenomena; Chlorpheniramine; Cimetidine; Dose-Response Relationship | 1985 |
Phentolamine and structurally related compounds selectively antagonize the vascular actions of the K+ channel opener, cromromakalim.
Topics: Animals; Benzopyrans; Coronary Vessels; Cromakalim; Dogs; Drug Interactions; Guinea Pigs; In Vitro T | 1989 |
Characterization of an endothelial 5-hydroxytryptamine (5-HT) receptor mediating relaxation of the porcine coronary artery.
Topics: Animals; Citalopram; Coronary Vessels; Corticosterone; Endothelium, Vascular; Gossypol; In Vitro Tec | 1989 |
Endothelial potentiation of relaxation response to phentolamine in rat thoracic aorta.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aorta, Thoracic; Endothelium, Vascular; In Vitro Technique | 1988 |
Different innervation mechanisms between the lesser and greater curvature of guinea pig antrum.
Topics: Animals; Apamin; Atropine; Chymotrypsin; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Cont | 1989 |
Effects of Na+,K+-pump inhibitors and membrane depolarizing agents on acetylcholine-induced endothelium-dependent relaxation and cyclic GMP accumulation in rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Biological Transport, Active; Cyclic GMP; Endothelium; In V | 1985 |
Relaxation of vascular smooth muscle by HA-1004, an inhibitor of cyclic nucleotide-dependent protein kinase.
Topics: Adenosine Triphosphatases; Animals; Atropine; Calcimycin; Calcium Chloride; Cyclic AMP; Cyclic GMP; | 1985 |
Nerve pathways involved in adrenergic regulation of electrical and mechanical activities in the chicken rectum.
Topics: Animals; Chickens; Electric Stimulation; Ileum; In Vitro Techniques; Male; Membrane Potentials; Musc | 1987 |
Possible prostacyclin involvement on disparate tonic responses to "in vitro" norepinephrine in circular and in longitudinal preparations from rat thoracic aorta.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Dose-Re | 1987 |
Gastric relaxation and vasoactive intestinal peptide output in response to reflex vagal stimulation in the dog.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Electric Stimu | 1988 |
Micturition in the unanesthetized rat: spinal vs. peripheral pharmacology of the adrenergic system.
Topics: Animals; Isoproterenol; Methoxamine; Muscle Contraction; Muscle Relaxation; Norepinephrine; Peripher | 1988 |
Spontaneous contractions and some electrophysiologic properties of circular muscle from normal sigmoid colon and ulcerative colitis.
Topics: Adult; Aged; Aged, 80 and over; Atropine; Colitis, Ulcerative; Colon, Sigmoid; Electric Stimulation; | 1988 |
Age-dependent changes in the response of isolated beagle coronary arteries to transmural electrical stimulation and catecholamines.
Topics: Acetylcholine; Aging; Animals; Catecholamines; Coronary Circulation; Coronary Vessels; Dinoprost; Do | 1986 |
Relaxant effects of vasoactive intestinal peptide and peptide histidine isoleucine in human and bovine pulmonary arteries.
Topics: Adenosine Triphosphate; Animals; Atropine; Cattle; Endothelium; Humans; In Vitro Techniques; Indomet | 1987 |
Two types of relaxation due to capsaicin in the guinea pig isolated ileum.
Topics: Animals; Atropine; Capsaicin; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Muscle Contraction | 1987 |
Vagally mediated gastric relaxation induced by intestinal nutrients in the dog.
Topics: Animals; Dogs; Gastrointestinal Contents; Homeostasis; Models, Biological; Muscle Contraction; Muscl | 1986 |
Analysis of the relaxing effect of dopamine on the isolated rat jejunum.
Topics: Animals; Cocaine; Dopamine; Flupenthixol; Haloperidol; In Vitro Techniques; Jejunum; Male; Methachol | 1986 |
Phentolamine and rat aortic smooth muscle responsiveness to potassium chloride, isoproterenol and norepinephrine.
Topics: Animals; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nore | 1985 |