phentolamine has been researched along with Morphine Abuse in 7 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
| Excerpt | Relevance | Reference |
|---|---|---|
| "morphine was suppressed by combined injection of adrenergic blockers, 10 mg/kg i." | 1.28 | Development of physical dependence on morphine not accompanied with tolerance formation. ( Kaneto, H; Ohta, A, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, Y | 1 |
| Qu, H | 1 |
| Zhou, Y | 1 |
| Wang, Y | 1 |
| Zhang, D | 1 |
| Yang, X | 2 |
| Yang, C | 1 |
| Xu, M | 1 |
| Wu, Y | 1 |
| Li, Y | 1 |
| Sui, N | 1 |
| Ohta, A | 1 |
| Kaneto, H | 1 |
| Katovich, MJ | 1 |
| Simpkins, JW | 1 |
| Barney, CC | 1 |
| Dixon, WR | 1 |
| Chang, AP | 1 |
| Cicero, TJ | 1 |
| Meyer, ER | 1 |
| Bell, RD | 1 |
| Pollock, D | 1 |
| Muir, TC | 1 |
| MacDonald, A | 1 |
| Henderson, G | 1 |
7 other studies available for phentolamine and Morphine Abuse
| Article | Year |
|---|---|
The involvement of norepinephrine in pain modulation in the nucleus accumbens of morphine-dependent rats.
Topics: Adrenergic alpha-Antagonists; Animals; Electric Stimulation; Evoked Potentials; Male; Morphine Depen | 2015 |
Differential effect of beta-adrenergic receptor antagonism in basolateral amygdala on reconsolidation of aversive and appetitive memories associated with morphine in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amygdala; Analysis of Variance; Animals; | 2014 |
Development of physical dependence on morphine not accompanied with tolerance formation.
Topics: Analgesia; Animals; Drug Interactions; Drug Tolerance; Injections, Intraperitoneal; Injections, Subc | 1992 |
Alpha-adrenergic mediation of the tail skin temperature response to naloxone in morphine-dependent rats.
Topics: Animals; Body Temperature; Brain; Clonidine; Female; Morphine Dependence; Naloxone; Phentolamine; Ra | 1987 |
Effect of phentolamine on blood pressure, heart rate and plasma catecholamine levels in conscious, unrestrained morphine dependent rats during naloxone precipitated autonomic withdrawal responses.
Topics: Animals; Blood Pressure; Dopamine; Epinephrine; Heart Rate; Morphine Dependence; Naloxone; Norepinep | 1988 |
Effects of phenoxybenzamine on the narcotic withdrawal syndrome in the rat.
Topics: Adrenergic beta-Antagonists; Animals; Behavior, Animal; Body Weight; Chlorpromazine; Depression, Che | 1974 |
Morphine-induced changes in the sensitivity of the isolated colon and vas deferens of the rat.
Topics: Acetylcholine; Animals; Atropine; Colon; Dose-Response Relationship, Drug; Furans; Humans; In Vitro | 1972 |