phentolamine has been researched along with Ischemic Attack, Transient in 15 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
Ischemic Attack, Transient: Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Aspirin effectively abolished SPA in 50 patients and relieved the clinical symptoms of patients with recurrent complaints of transient blindness and paraesthesia." | 3.66 | Spontaneous platelet aggregation in cerebrovascular disease. ( Jenkins, CS; Oosterhuis, H; Prenger, D; ten Cate, JW; Vos, J, 1978) |
| "Hypertension is a primary aggravating factor in cerebral infarction." | 1.29 | M1 receptors in blood pressure-controlled ischemic spontaneously hypertensive rats. ( Asanuma, M; Hirata, H; Kondo, Y; Ogawa, N; Tanaka, K, 1995) |
| "Phentolamine was ineffective." | 1.26 | Mechanism of cerebral arterial contraction induced by blood constituents. ( Ohta, T; Shimizu, K; Toda, N, 1980) |
| "Phentolamine, that is an adrenergic blocking agent, relieved the early spam remarkably, but it was less effective on the late spam." | 1.25 | [Experimental Subarachnoid hemmorrhage in dogs--effect of various drugs and sympathectomy on cerebral arterial spasm (author's transl)]. ( Noda, S, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (86.67) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SAMMARTINO, WF | 1 |
| TOOLE, JF | 1 |
| Jaswal, JS | 1 |
| Gandhi, M | 1 |
| Finegan, BA | 1 |
| Dyck, JR | 1 |
| Clanachan, AS | 1 |
| Toda, N | 1 |
| Shimizu, K | 1 |
| Ohta, T | 1 |
| Hirata, H | 1 |
| Asanuma, M | 1 |
| Tanaka, K | 1 |
| Kondo, Y | 1 |
| Ogawa, N | 1 |
| Takagi, S | 1 |
| Sakaki, S | 1 |
| Kimoto, K | 1 |
| Hossmann, KA | 1 |
| ten Cate, JW | 1 |
| Vos, J | 1 |
| Oosterhuis, H | 1 |
| Prenger, D | 1 |
| Jenkins, CS | 1 |
| Martins, AN | 2 |
| Newby, N | 1 |
| Doyle, TF | 1 |
| Kobrine, AI | 1 |
| Ramirez, A | 1 |
| Nagai, H | 1 |
| Noda, S | 2 |
| Mabe, H | 1 |
| Wiley, JK | 1 |
| Rosenblum, WI | 1 |
| Flamm, ES | 2 |
| Yasargil, MG | 1 |
| Ransohoff, J | 2 |
| Smigiel, MR | 1 |
| Sundt, TM | 1 |
| Echlin, FA | 1 |
1 review available for phentolamine and Ischemic Attack, Transient
| Article | Year |
|---|---|
Current concepts in the etiology and treatment of vasospasm.
Topics: Animals; Brain Edema; Cerebral Angiography; Cerebral Arteries; Cerebrovascular Circulation; Disease | 1968 |
14 other studies available for phentolamine and Ischemic Attack, Transient
| Article | Year |
|---|---|
REVERSED VERTEBRAL ARTERY FLOW. THE EFFECT OF LIMB EXERCISE AND HYPERTENSIVE AGENTS.
Topics: Animals; Blood Circulation; Blood Pressure; Brachiocephalic Trunk; Carotid Arteries; Cerebral Infarc | 1964 |
Effects of adenosine on myocardial glucose and palmitate metabolism after transient ischemia: role of 5'-AMP-activated protein kinase.
Topics: Acetyl-CoA Carboxylase; Adenine; Adenosine; Adenosine Triphosphate; Adrenergic alpha-Antagonists; AM | 2006 |
Mechanism of cerebral arterial contraction induced by blood constituents.
Topics: Animals; Aspirin; Cerebrovascular Circulation; Cinanserin; Dogs; Female; Hemoglobins; Ischemic Attac | 1980 |
M1 receptors in blood pressure-controlled ischemic spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Cerebrovascular Circulation; Cerebrovascular Disorders; Frontal Lobe; Hippo | 1995 |
[Pial arterial responses in the cat brain following prolonged ischemia (author's transl)].
Topics: Animals; Arteries; Calcium; Cats; Hydrogen-Ion Concentration; Ischemic Attack, Transient; Norepineph | 1978 |
Spontaneous platelet aggregation in cerebrovascular disease.
Topics: Adenosine; Adenosine Diphosphate; Adult; Aged; Aspirin; Blindness; Brain Diseases; Female; Humans; I | 1978 |
Effect of intracisternal phentolamine on cerebral blood flow after subarachnoid injection of blood.
Topics: Animals; Blood Pressure; Blood Transfusion, Autologous; Cerebrovascular Circulation; Cisterna Magna; | 1976 |
Experimental cerebral vasospasm. Part 2: effects of vasoactive drugs and sympathectomy on early and late spasm.
Topics: Animals; Circle of Willis; Disease Models, Animal; Dogs; Ischemic Attack, Transient; Isoxsuprine; Me | 1975 |
[Experimental Subarachnoid hemmorrhage in dogs--effect of various drugs and sympathectomy on cerebral arterial spasm (author's transl)].
Topics: Animals; Autonomic Agents; Cerebral Arteries; Dogs; Ischemic Attack, Transient; Isoxsuprine; Methyse | 1975 |
Side effects of spasmolytic agents in the monkey. Intracisternal phenoxybenzamine and phentolamine.
Topics: Animals; Dose-Response Relationship, Drug; Electroencephalography; Haplorhini; Hypotension; Injectio | 1973 |
Cerebral arteriolar spasm inhibited by beta-adrenergic blocking agents.
Topics: Animals; Barium; Cerebral Arterial Diseases; Injections, Subcutaneous; Ischemic Attack, Transient; I | 1969 |
Alteration of experimental cerebral vasospasm by adrenergic blockade.
Topics: Adrenergic alpha-Antagonists; Animals; Basilar Artery; Blood Flow Velocity; Blood Pressure; Cats; Di | 1972 |
Comparative effectiveness of alpha-blockade and beta-stimulation in modifying experimental basilar arterial spasm.
Topics: Animals; Basilar Artery; Cats; Drug Evaluation, Preclinical; Ischemic Attack, Transient; Isoproteren | 1974 |
Subarachnoid administration of phentolamine for experimental cerebral vasospasm.
Topics: Animals; Cats; Injections; Ischemic Attack, Transient; Phentolamine; Subarachnoid Space | 1972 |