phentolamine has been researched along with Inflammation in 14 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mechanical hyperalgesia, however, was less sensitive to inhibition by propranolol and guanethedine but significantly inhibited by phentolamine." | 1.31 | The role of the sympathetic efferents in endotoxin-induced localized inflammatory hyperalgesia and cytokine upregulation. ( Haddad, JJ; Jabbur, SJ; Massaad, CA; Poole, S; Saadé, NE; Safieh-Garabedian, B, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (57.14) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Couvineau, A | 1 |
| Gomariz, RP | 1 |
| Tan, YV | 1 |
| Miao, FJ | 1 |
| Green, P | 1 |
| Benowitz, N | 1 |
| Levine, JD | 1 |
| FRANK, L | 1 |
| RAPP, Y | 1 |
| BIRO, L | 1 |
| GLICKMAN, FS | 1 |
| Egger, G | 1 |
| Teno, S | 1 |
| Tanabe, A | 1 |
| Nomura, K | 1 |
| Demura, H | 1 |
| Safieh-Garabedian, B | 1 |
| Poole, S | 1 |
| Haddad, JJ | 1 |
| Massaad, CA | 1 |
| Jabbur, SJ | 1 |
| Saadé, NE | 1 |
| Drózdz, M | 1 |
| Kucharz, E | 1 |
| Wieczorek, M | 1 |
| Bengtsson, E | 1 |
| Rainsford, KD | 1 |
| Galer, BS | 1 |
| Rowbotham, MC | 1 |
| Miller, KV | 1 |
| Walton, A | 1 |
| Fields, HL | 1 |
| Somogyi, A | 1 |
| Selye, H | 1 |
| Green, KL | 1 |
| Hopkins, RW | 1 |
14 other studies available for phentolamine and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Editorial: GPCR in Inflammatory and Cancer Diseases.
Topics: Angiotensin-Converting Enzyme 2; Arthritis, Rheumatoid; Autoimmune Diseases; Drug Combinations; Gast | 2020 |
Vagal modulation of spinal nicotine-induced inhibition of the inflammatory response mediated by descending antinociceptive controls.
Topics: Adrenergic alpha-Antagonists; Animals; Bradykinin; Capillary Permeability; Dose-Response Relationshi | 2003 |
INFLAMMATION MEDIATORS AND THE INFLAMMATORY REACTION.
Topics: Anti-Allergic Agents; Bradykinin; Capillary Permeability; Chlorpheniramine; Cyproheptadine; Fluoresc | 1964 |
Modifications in the regression of the acute inflammation caused by a beta-adrenergic effect unbalanced by the alpha-component ("biased beta-effect").
Topics: Animals; Catecholamines; Cell Movement; Dextrans; Inflammation; Isoproterenol; Lymphocytes; Male; Ph | 1982 |
Acutely exacerbated hypertension and increased inflammatory signs due to radiation treatment for metastatic pheochromocytoma.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Bone Neoplasms; Female; Heart Rate; Humans; Hyperten | 1996 |
The role of the sympathetic efferents in endotoxin-induced localized inflammatory hyperalgesia and cytokine upregulation.
Topics: Adrenergic alpha-Antagonists; Adrenergic Antagonists; Adrenergic Fibers; Animals; Cytokines; Dose-Re | 2002 |
Morphological changes observed after stimulation or inhibition of adrenic system in rats chronically treated with hydrazinophtalazines.
Topics: Animals; Catecholamines; Epinephrine; Heart; Heart Diseases; Hemorrhage; Hydralazine; Inflammation; | 1979 |
The difference between the influence of prostaglandin and alpha-melanocyte stimulating hormone on the blood aqueous barrier.
Topics: Animals; Aqueous Humor; Eye; Eye Diseases; Inflammation; Infrared Rays; Iris; Melanocyte-Stimulating | 1977 |
The role of aspirin in gastric ulceration . Some factors involved in the development of gastric mucosal damage induced by aspirin in rats exposed to various stress conditions.
Topics: Animals; Arthritis, Experimental; Aspirin; Atropine Derivatives; Bethanechol Compounds; Cold Tempera | 1978 |
Treatment of inflammatory, neuropathic and sympathetically maintained pain in a patient with Sjögren's syndrome.
Topics: Action Potentials; Adult; Female; Humans; Inflammation; Lidocaine; Nerve Block; Pain; Pain Managemen | 1992 |
Tourniquet poditis--an experimental pedal inflammation in the rat.
Topics: Animals; Anti-Bacterial Agents; Chlorpromazine; Cyproheptadine; Depression, Chemical; Dextrans; Dibe | 1969 |
Mechanism of the pro-inflammatory activity of sympathomimetic amines in thermic oedema of the rat paw.
Topics: Animals; Blood Circulation; Bradykinin; Capillary Permeability; Edema; Epinephrine; Foot; Heparin; H | 1974 |
Septic shock: hemodynamic cost of inflammation.
Topics: Animals; Arteries; Calcium Chloride; Dogs; Hemodynamics; Hindlimb; Hyperemia; Inflammation; Methylpr | 1970 |