phentolamine has been researched along with Hypothermia, Accidental in 13 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypothermia is the major factor influencing autoregulatory properties of the cerebral circulation in human infants undergoing hypothermic cardiopulmonary bypass." | 1.29 | Hypothermia enhances contractility in cerebral arteries of newborn lambs. ( Davis, DA; Russo, P; Speziali, G; Wagerle, LC, 1994) |
| " The distribution of experimental points suggested a sigmoidal dose-response curve." | 1.26 | Effect of environmental temperature on glucose-induced insulin response in the newborn rat. ( Assan, R; Gilbert, M; Girard, JR; Jost, A; Kervran, A, 1976) |
| "3 A second cannabis extract (II) with a different ratio of cannabinoids (also administered in dosage equivalent to 10 mg Delta(9)-THC/kg) failed to affect pentobarbitone anaesthesia in mice." | 1.25 | Interaction of cannabis and general anaesthetic agents in mice. ( Chesher, GB; Jackson, DM; Starmer, GA, 1974) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (84.62) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| HINSHAW, LB | 1 |
| MASUCCI, FD | 1 |
| BRAKE, CM | 1 |
| WITTMERS, LE | 1 |
| EMERSON, TE | 1 |
| Speziali, G | 1 |
| Russo, P | 1 |
| Davis, DA | 1 |
| Wagerle, LC | 1 |
| Kervran, A | 1 |
| Gilbert, M | 1 |
| Girard, JR | 1 |
| Assan, R | 1 |
| Jost, A | 1 |
| Sakuragi, T | 1 |
| Shono, S | 1 |
| Isino, H | 1 |
| Oyama, T | 1 |
| Dan, K | 1 |
| Kulinskiĭ, VI | 1 |
| Gertsov, GE | 1 |
| Plotnikov, NIu | 1 |
| Bezachev, VG | 1 |
| Chesher, GB | 1 |
| Jackson, DM | 1 |
| Starmer, GA | 1 |
| Porte, D | 2 |
| Robertson, RP | 1 |
| Kar, K | 1 |
| Sur, RN | 1 |
| Pradhan, SN | 1 |
| Kendle, KE | 1 |
| Bennett, JP | 1 |
| Baum, D | 1 |
| Coper, H | 1 |
| Lison, H | 1 |
| Rommelspacher, H | 1 |
| Schulze, G | 1 |
| Strauss, S | 1 |
| Nakamura, K | 1 |
| Thoenen, H | 1 |
| Cooper, F | 1 |
| Leonard, BE | 1 |
| Schnieden, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| NICardipine Neuroprotection in AortiC Surgery (NICNACS)[NCT00508118] | Phase 2 | 7 participants (Actual) | Interventional | 2008-01-31 | Terminated (stopped due to 3/7 subjects experienced hypotension. Study was terminated.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT00508118)
Timeframe: Day of surgery
| Intervention | Time (minutes) (Median) |
|---|---|
| NICARDIPINE GROUP | 45 |
1 review available for phentolamine and Hypothermia, Accidental
| Article | Year |
|---|---|
Control of insulin secretion by catecholamines, stress, and the sympathetic nervous system.
Topics: Animals; Caffeine; Catecholamines; Cyclic AMP; Diazoxide; Epinephrine; Glucose; Hypothermia; Hypoxia | 1973 |
12 other studies available for phentolamine and Hypothermia, Accidental
| Article | Year |
|---|---|
RENAL VASCULAR RESPONSE TO HYPOTHERMIA.
Topics: Blood Pressure; Blood Viscosity; Dogs; Hypothermia; Hypothermia, Induced; Kidney; Perfusion; Pharmac | 1965 |
Hypothermia enhances contractility in cerebral arteries of newborn lambs.
Topics: Animals; Animals, Newborn; Arginine; Cerebral Arteries; Dose-Response Relationship, Drug; Hypothermi | 1994 |
Effect of environmental temperature on glucose-induced insulin response in the newborn rat.
Topics: Age Factors; Animals; Animals, Newborn; Blood Glucose; Body Temperature; Cesarean Section; Female; G | 1976 |
[Hypothermia after cardiopulmonary bypass in man: effects of prostaglandin E1 and phentolamine].
Topics: Adult; Aged; Alprostadil; Body Temperature; Cardiopulmonary Bypass; Female; Humans; Hypothermia; Mal | 1990 |
[Changes in the sensitivity of the alpha 2- and beta 1-adrenoreactive systems during the intensive cooling of rats acclimatized to cold].
Topics: Acclimatization; Animals; Clonidine; Cold Temperature; Female; Heart Rate; Hypothermia; Isoprotereno | 1988 |
Interaction of cannabis and general anaesthetic agents in mice.
Topics: Anesthesia, General; Animals; Cannabis; Desipramine; Dronabinol; Drug Synergism; Ethyl Ethers; Fencl | 1974 |
Depressor response to noradrenaline in hypothermic cats.
Topics: Acetazolamide; Acetylcholine; Animals; Atropine; Bicarbonates; Blood Pressure; Calcium; Cats; Depres | 1969 |
Studies upon the mechanism of reserpine-induced arrest in egg transport in the mouse oviduct. II. Comparative effects of some agents with actions on smooth muscle and tissue amines.
Topics: Amphetamine; Animals; Atropine; Catecholamines; Chlorpromazine; Ethanolamines; Female; Guanethidine; | 1969 |
Alpha-adrenergic inhibition of immunoreactive insulin release during deep hypothermia.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Glucose; Blood Pressure; B | 1971 |
The influence of adrenergic receptor-blocking agents, amphetamine, and 6-aminonicotinamide on thermoregulation.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amines; Amphetamine; Animals; Body Temper | 1971 |
Hypothermia induced by intraventricular administration of 6-hydroxydopamine in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Brain; Cocaine; Desipramine; Dop | 1971 |
The role of catecholamines in the reversal of reserpine-induced hypothermia in mice by desipramine and chlorpromazine.
Topics: Animals; Body Temperature; Catecholamines; Chlorpromazine; Desipramine; Dihydroxyphenylalanine; Dose | 1972 |