phentolamine has been researched along with Hypertension, Portal in 12 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
Hypertension, Portal: Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Anaphylactic shock is sometimes life-threatening, and it is accompanied by hepatic venoconstriction in animals, which, in part, accounts for anaphylactic hypotension." | 1.39 | Alpha-adrenoceptor antagonists and chemical sympathectomy exacerbate anaphylaxis-induced hypotension, but not portal hypertension, in anesthetized rats. ( Kurata, Y; Shibamoto, T; Tanida, M; Wang, M, 2013) |
| "When phentolamine was used in combination with pituitrin no side effect was found in hepatic and systemic hemodynamics." | 1.28 | [Effect of phentolamine in combination with pituitrin on the hepatic and systemic hemodynamics]. ( Dan, Z, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, HC | 2 |
| Chang, CC | 2 |
| Pun, CK | 1 |
| Tsai, MH | 1 |
| Chuang, CL | 1 |
| Hsu, SJ | 1 |
| Huang, YH | 1 |
| Hou, MC | 1 |
| Lee, FY | 2 |
| Wang, M | 1 |
| Tanida, M | 1 |
| Shibamoto, T | 1 |
| Kurata, Y | 1 |
| Sastre, E | 1 |
| Balfagón, G | 1 |
| Revuelta-López, E | 1 |
| Aller, MÁ | 2 |
| Nava, MP | 1 |
| Arias, J | 2 |
| Blanco-Rivero, J | 1 |
| MENA, I | 2 |
| ORREGO, H | 2 |
| BARAONA, E | 2 |
| MARQUES, S | 2 |
| Chan, CC | 1 |
| Wang, SS | 1 |
| Chang, FY | 1 |
| Lin, HC | 1 |
| Tai, CC | 1 |
| Lee, SD | 1 |
| Wu, ZY | 1 |
| Benoit, JN | 1 |
| Zhu, J | 1 |
| Leng, X | 1 |
| Yin, J | 1 |
| Dan, Z | 1 |
| Dan, ZL | 1 |
| Zhao, Q | 1 |
| Li, SB | 1 |
| Epstein, M | 1 |
| Berk, DP | 1 |
| Hollenberg, NK | 1 |
| Adams, DF | 1 |
| Chalmers, TC | 1 |
| Abrams, HL | 1 |
| Merrill, JP | 1 |
12 other studies available for phentolamine and Hypertension, Portal
| Article | Year |
|---|---|
α-Adrenergic blockade prevented environmental temperature reduction-induced transient portal pressure surge in cirrhotic and portal hypertensive rats.
Topics: Adrenergic beta-Antagonists; Animals; Epinephrine; Esophageal and Gastric Varices; Gastrointestinal | 2022 |
Alpha-adrenoceptor antagonists and chemical sympathectomy exacerbate anaphylaxis-induced hypotension, but not portal hypertension, in anesthetized rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Anaphylaxis; Animals; Hypertension, Portal; Hypotension; Li | 2013 |
Effect of short- and long-term portal hypertension on adrenergic, nitrergic and sensory functioning in rat mesenteric artery.
Topics: Animals; Blood Pressure; Blotting, Western; Body Weight; Calcitonin Gene-Related Peptide; Electric S | 2012 |
[Effects of regitine and reserpine on portal hypertension].
Topics: Humans; Hypertension; Hypertension, Portal; Phentolamine; Reserpine | 1963 |
EFFECTS OF REGITINE AND RESERPINE ON PORTAL HYPERTENSION.
Topics: Alcoholism; Ascites; Esophageal and Gastric Varices; Humans; Hypertension; Hypertension, Portal; Liv | 1963 |
Effects of norepinephrine and acetylcholine on portal-systemic collaterals of common bile duct-ligated cirrhotic rat.
Topics: Acetylcholine; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertens | 2005 |
Portal systemic collateral development: is it a trophic adaptation mechanism to hepatic deprivation?
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Collateral | 2006 |
Effects of propranolol on intestinal microcirculation of normal and portal hypertensive rats.
Topics: Animals; Drug Administration Routes; Hemodynamics; Hypertension, Portal; Intestines; Male; Microcirc | 1995 |
[Effect of phentolamine on portal pressure in cirrhotic patients with portal hypertension].
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Blood Pressure; Female; Heart Rate; Humans; Hypertension, | 1997 |
[Effect of phentolamine in combination with pituitrin on the hepatic and systemic hemodynamics].
Topics: Animals; Dogs; Drug Therapy, Combination; Female; Hemodynamics; Hypertension, Portal; Liver Circulat | 1990 |
The effects of the combination of phentolamine and vasopressin on hepatic and systemic hemodynamics in cirrhotic portal hypertensive dog model.
Topics: Animals; Dogs; Drug Therapy, Combination; Esophageal and Gastric Varices; Female; Hemodynamics; Hype | 1991 |
Renal failure in the patient with cirrhosis. The role of active vasoconstriction.
Topics: Adult; Aged; Angiography; Blood Flow Velocity; Blood Pressure; Brain Diseases; Constriction; Creatin | 1970 |