phentolamine has been researched along with Hypercapnia in 22 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
Hypercapnia: A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neotenic larval Ambystoma tigrinum were subjected to hypercapnia (3% CO2, 22 Torr) for 24 h under different conditions: alpha-adrenergic blockade using phentolamine, beta-adrenergic blockade using propranolol, and sham treatments." | 3.68 | Acid-base-electrolyte balance responses to catecholamine antagonists in Ambystoma tigrinum. ( Boutilier, RG; Kopecky, ME; Stiffler, DF; Thompson, ML, 1990) |
| "In advanced respiratory insufficiency hypoxemia is often accompanied by hypercapnia, which is the stimulus for central chemoreceptors as well as for carotid body chemoreceptors." | 1.32 | Influence of the stimulation of central chemoreceptors on the gastric mucosal blood flow in artificially ventilated and spontaneously breathing rats. ( Kowalczyk, P; Przybylski, J; Sawionek, Ł; Siński, M; Stolarczyk, A, 2003) |
| "Hypercapnia was produced by increasing the fractional concentration of inspired CO2 (FICO2)." | 1.27 | Regional neurohypophysial and hypothalamic blood flow in rats during hypercapnia. ( Bryan, RM; Myers, CL; Page, RB, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (72.73) | 18.7374 |
| 1990's | 3 (13.64) | 18.2507 |
| 2000's | 2 (9.09) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Koshika, K | 1 |
| Kaneko, R | 1 |
| Shionoya, M | 1 |
| Shimizu, K | 1 |
| Sendai, Y | 1 |
| Matsuura, N | 1 |
| Akiike, Y | 1 |
| Ichinohe, T | 1 |
| Roatta, S | 1 |
| Canova, D | 1 |
| Bosone, D | 1 |
| Micieli, G | 1 |
| Passatore, M | 1 |
| Siński, M | 1 |
| Kowalczyk, P | 1 |
| Stolarczyk, A | 1 |
| Sawionek, Ł | 1 |
| Przybylski, J | 1 |
| Barer, GR | 2 |
| McCurrie, JR | 2 |
| Lagneaux, D | 1 |
| Remacle, R | 1 |
| Wei, EP | 1 |
| Kontos, HA | 1 |
| Patterson, JL | 1 |
| O'Halloran, KD | 1 |
| Janssen, PL | 1 |
| Bisgard, GE | 1 |
| Edvinsson, L | 1 |
| Lacombe, P | 1 |
| Owman, C | 1 |
| Reynier-Rebuffel, AM | 1 |
| Seylaz, J | 1 |
| Marotta, SF | 1 |
| Sithichoke, N | 1 |
| Garcy, AM | 1 |
| Yu, M | 1 |
| Hyman, AL | 1 |
| Kadowitz, PJ | 1 |
| Taylor, JF | 1 |
| Lee, JC | 1 |
| Downing, SE | 1 |
| Stepanek, J | 3 |
| Johansson, B | 1 |
| Nilsson, B | 1 |
| Williams, JL | 1 |
| Jones, SC | 1 |
| Page, RB | 2 |
| Bryan, RM | 2 |
| Stiffler, DF | 1 |
| Kopecky, ME | 1 |
| Thompson, ML | 1 |
| Boutilier, RG | 1 |
| Wexels, JC | 1 |
| Myhre, ES | 1 |
| Myers, CL | 1 |
| Manley, ES | 1 |
| Woodbury, RA | 1 |
| Nash, CB | 1 |
| Pannier, JL | 1 |
| Leusen, I | 1 |
| Howard, P | 1 |
| Shaw, JW | 1 |
22 other studies available for phentolamine and Hypercapnia
| Article | Year |
|---|---|
Involvement of α- and β-Adrenergic Receptors in Skeletal Muscle Blood Flow Changes During Hyper-/Hypocapnia in Anesthetized Rabbits.
Topics: Animals; Atropine Derivatives; Blood Pressure; Butoxamine; Hypercapnia; Hypocapnia; Metaproterenol; | 2023 |
Noradrenergic constriction of cerebral arteries as detected by transcranial Doppler (TCD) in the rabbit.
Topics: Adrenergic alpha-Antagonists; Animals; Basilar Artery; Blood Flow Velocity; Carotid Artery, Internal | 2003 |
Influence of the stimulation of central chemoreceptors on the gastric mucosal blood flow in artificially ventilated and spontaneously breathing rats.
Topics: Administration, Inhalation; Animals; Blood Pressure; Carbon Dioxide; Carotid Body; Chemoreceptor Cel | 2003 |
Inhibition of the vasoconstrictor action of hypoxia on the pulmonary circulation by drugs.
Topics: Animals; Cats; Dopamine; Histamine; Hypercapnia; Hypoxia; Norepinephrine; Phentolamine; Pulmonary Ci | 1967 |
[Cardio-vascular reactions to respiratory hypercapnia in rats].
Topics: Animals; Blood Pressure; Carbon Dioxide; Heart Rate; Hypercapnia; Phentolamine; Rats; Vagotomy | 1981 |
Dependence of pial arteriolar response to hypercapnia on vessel size.
Topics: Animals; Arteries; Arterioles; Cats; Hypercapnia; Phentolamine; Pia Mater; Sympathetic Nervous Syste | 1980 |
Dopaminergic modulation of respiratory motor output in peripherally chemodenervated goats.
Topics: Adrenergic alpha-Antagonists; Animals; Carotid Body; Dopamine; Dopamine Agonists; Female; Goats; Hem | 1998 |
Quantitative changes in regional cerebral blood flow of rats induced by alpha- and beta-adrenergic stimulants.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Carbon Dioxide; Cerebrovascular Circul | 1979 |
Adrenocortical responses of rats to acute hypoxic and hypercapnic stresses after treatment with aminergic agents.
Topics: Adrenal Cortex; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Biogenic Amines; Bis(4-Methyl- | 1976 |
Effects of alveolar and perfusion hypoxia and hypercapnia on pulmonary vascular resistance in the lamb.
Topics: Animals; Blood Pressure; Carbon Dioxide; Diphenhydramine; Histamine; Hydrogen-Ion Concentration; Hyp | 1975 |
Effects of acidosis, catechols, and atrial function on pulmonary pressure gradients.
Topics: Acidosis; Animals; Blood Flow Velocity; Blood Pressure; Carbon Dioxide; Cardiac Output; Cats; Female | 1975 |
[Pathogenesis of acute hypercapnic hyperammoniaemia (author's transl)].
Topics: Ammonia; Animals; Dogs; Hypercapnia; Oxprenolol; Phentolamine; Vasoconstriction; Vasodilation | 1979 |
The pathophysiology of the blood-brain barrier dysfunction induced by severe hypercapnia and by epileptic brain activity.
Topics: Animals; Bicuculline; Blood Pressure; Blood-Brain Barrier; Epilepsy; Homocysteine; Hypercapnia; Hype | 1977 |
Effect of pretreatment with phentolamine on experimentally induced hypercapnia.
Topics: Animals; Carbon Dioxide; Cardiac Output; Dogs; Hemodynamics; Hypercapnia; Oxygen; Oxygen Consumption | 1975 |
Vascular responses of choroid plexus during hypercapnia in rats.
Topics: Amphetamines; Animals; Autoradiography; Blood-Brain Barrier; Catecholamines; Cerebrovascular Circula | 1991 |
Acid-base-electrolyte balance responses to catecholamine antagonists in Ambystoma tigrinum.
Topics: Acid-Base Equilibrium; Ambystoma; Animals; Carbon Dioxide; Catecholamines; Electrolytes; Electrophys | 1990 |
Hypocapnia and hypercapnia in the dog: effects on myocardial blood-flow and haemodynamics during beta- and combined alpha- and beta-adrenoceptor blockade.
Topics: Animals; Blood Pressure; Carbon Dioxide; Cardiac Output; Coronary Circulation; Dogs; Epinephrine; He | 1987 |
Regional neurohypophysial and hypothalamic blood flow in rats during hypercapnia.
Topics: Amphetamines; Animals; Carbon Dioxide; Cerebrovascular Circulation; Hypercapnia; Hypothalamo-Hypophy | 1988 |
Cardiovascular responses to epinephrine during acute hypercapnia in dogs: effects of autonomic blocking drugs.
Topics: Acetylcholine; Animals; Atropine; Autonomic Nerve Block; Carbon Dioxide; Cardiovascular System; Chlo | 1966 |
[Cardiopulmonary effects of phentolamine in the dog].
Topics: Animals; Cardiac Volume; Dogs; Heart Rate; Hypercapnia; Hypoxia; Phentolamine; Respiration | 1974 |
Circulation to the brain of the rat during acute and prolonged respiratory changes in the acid-base balance.
Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Alkalosis, Respiratory; Animals; Blood Pressure; Brain | 1973 |
Changes in the pulmonary circulation after bronchial occlusion in anesthetized dogs and cats.
Topics: Air; Animals; Bicarbonates; Blood Flow Velocity; Blood Pressure; Bretylium Compounds; Cats; Dogs; Hy | 1969 |