Page last updated: 2024-11-06

phentolamine and Hemorrhagic Shock

phentolamine has been researched along with Hemorrhagic Shock in 27 studies

Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.

Research Excerpts

ExcerptRelevanceReference
"Isoproterenol was infused at 2."5.27The effects of phentolamine and isoproterenol in experimental hemorrhagic shock in the dog. ( Abel, FL; Liu, ZM; Rodriquez, LF, 1984)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199026 (96.30)18.7374
1990's1 (3.70)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
SCHAPOSNIK, F1
Dietzman, RH2
Manax, WG1
Lillehei, RC2
Ikrényi, C1
Koltay, E1
Kovách, AG1
Liu, ZM1
Abel, FL1
Rodriquez, LF1
Pressier, VM1
Suehiro, A1
Lum, J1
Mori, K1
McNamara, JJ1
Richardson, PD1
Granger, DN1
Taylor, AE1
Menguy, R1
Masters, YF1
Schaumloffel, V1
Pugh, V1
Bealer, SL1
Xie, CW1
Han, JS1
Wei, ZY1
Wang, JQ1
Pan, XJ1
Conlay, LA1
Maher, TJ1
Wurtman, RJ1
Lindsey, CA1
Faloona, GR1
Unger, RH1
Hiebert, JM1
Sixt, N1
Soeldner, JS1
Egdahl, RH1
Cerchio, GM2
Persico, PA2
Jeffay, H1
Grandchamp, A1
Ayer, G1
Truniger, B1
Corssen, G1
Chodoff, P1
Nelson, NC1
Nelson, JL1
Weldon, WE1
Vela, AR1
Motsay, GJ1
Hardaway, RM1
Halmagyi, DF1
Kennedy, M1
Varga, D1
Messmer, K1
Gould, L1
Ettinger, S1
Carmichael, A1
Lord, P1
Hofstra, P1
Shoemaker, WC1
Brown, RS1
Schröder, R1
Torsti, P1
Dorobisz, T1
Palider, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effects of Supplementing Tyrosine on Blood Pressure in Parkinson's Disease[NCT01676103]Phase 1/Phase 240 participants (Actual)Interventional2012-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for phentolamine and Hemorrhagic Shock

ArticleYear
Capillary filtration coefficient: the technique and its application to the small intestine.
    Cardiovascular research, 1979, Volume: 13, Issue:10

    Topics: Adenosine; Adrenergic Agonists; Animals; Autacoids; Blood Volume; Capillaries; Capillary Permeabilit

1979

Other Studies

26 other studies available for phentolamine and Hemorrhagic Shock

ArticleYear
[SHOCK IN OBSTETRICS].
    El Dia medico, 1964, Mar-26, Volume: 36

    Topics: Abortion, Induced; Abortion, Spontaneous; Abruptio Placentae; Anti-Bacterial Agents; Blood Transfusi

1964
Shock: mechanisms and therapy.
    Canadian Anaesthetists' Society journal, 1967, Volume: 14, Issue:4

    Topics: Animals; Chlorpromazine; Digitalis Glycosides; Dogs; Endotoxins; Epinephrine; Equipment and Supplies

1967
Effect of alpha receptor blocking drugs and vasodilators on metabolic changes in hemorrhagic shock.
    Zeitschrift fur medizinische Laboratoriumsdiagnostik, 1982, Apr-02, Volume: 23, Issue:2

    Topics: Adrenergic alpha-Antagonists; Aminophylline; Animals; Energy Metabolism; Male; Phenoxybenzamine; Phe

1982
The effects of phentolamine and isoproterenol in experimental hemorrhagic shock in the dog.
    Circulatory shock, 1984, Volume: 14, Issue:1

    Topics: Animals; Blood Glucose; Blood Pressure; Capillary Permeability; Dogs; Female; Isoproterenol; Male; P

1984
Mechanisms of shock blood induced tissue anoxia.
    American journal of surgery, 1980, Volume: 140, Issue:1

    Topics: Animals; Hindlimb; Oxygen Consumption; Perfusion; Phentolamine; Platelet Count; Shock, Hemorrhagic;

1980
Mechanism of stress ulcer. Influence of alpha-adrenergic blockade on stress ulceration and gastric mucosal energy metabolism.
    The American journal of digestive diseases, 1978, Volume: 23, Issue:6

    Topics: Animals; Energy Metabolism; Gastric Mucosa; Male; Phentolamine; Rabbits; Shock, Hemorrhagic; Stomach

1978
Preoptic hypothalamic lesions reduce adrenergic vascular compensation during hemorrhagic shock.
    Circulatory shock, 1990, Volume: 31, Issue:2

    Topics: Animals; Hemodynamics; Male; Phentolamine; Prazosin; Preoptic Area; Rats; Rats, Inbred Strains; Rece

1990
[Alpha-adrenoceptors in the rat spinal cord: its role in baroreflex and hemorrhagic shock].
    Sheng li xue bao : [Acta physiologica Sinica], 1986, Volume: 38, Issue:2

    Topics: Animals; Clonidine; Female; Injections, Spinal; Male; Phentolamine; Pressoreceptors; Rats; Receptors

1986
[The pressor effect of naloxone phentolamine or cinanserine injected into the lateral cerebroventricle of rabbit with haemorrhagic or endotoxic shock].
    Sheng li xue bao : [Acta physiologica Sinica], 1988, Volume: 40, Issue:6

    Topics: Animals; Blood Pressure; Cinanserin; Cinnamates; Female; Injections, Intraventricular; Male; Naloxon

1988
Tyrosine accelerates catecholamine synthesis in hemorrhaged hypotensive rats.
    Brain research, 1985, Apr-29, Volume: 333, Issue:1

    Topics: Adrenal Glands; Animals; Blood Pressure; Carbidopa; Catecholamines; Male; Myocardium; Phentolamine;

1985
Glucagon and the insulin: glucagon ratio in severe trauma.
    Transactions of the Association of American Physicians, 1973, Volume: 86

    Topics: Adolescent; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Animals; Blood G

1973
Altered insulin and glucose metabolism produced by epinephrine during hemorrhagic shock in the adrenalectomized primate.
    Surgery, 1973, Volume: 74, Issue:2

    Topics: Adrenal Glands; Adrenalectomy; Animals; Blood Pressure Determination; Dose-Response Relationship, Dr

1973
Inhibition of insulin release during hypovolemic shock.
    Metabolism: clinical and experimental, 1973, Volume: 22, Issue:12

    Topics: Animals; Blood Glucose; Female; Glucose Tolerance Test; Haplorhini; Insulin; Insulin Secretion; Isle

1973
Pathogenesis of redistribution of intrarenal blood flow in haemorrhagic hypotension.
    European journal of clinical investigation, 1971, Volume: 1, Issue:4

    Topics: Acetylcholine; Angiotensin II; Animals; Autoradiography; Blood Flow Velocity; Dogs; Hypotension; Isc

1971
Clinical management of the patient in shock. Neurolept analgesia.
    Clinical anesthesia, 1965, Volume: 2

    Topics: Anesthesia; Benperidol; Female; Fentanyl; Humans; Isoproterenol; Middle Aged; Neuroleptanalgesia; Ph

1965
Mechanisms of change in thoracic duct lymph flow during hypotensive states.
    Annals of surgery, 1970, Volume: 171, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Aspirin; Capillary Permeability;

1970
Effect of hyperglycemia and adrenergic stimulation on growth hormone response during hypovolemic shock.
    Steroids and lipids research, 1974, Volume: 5, Issue:5-6

    Topics: Animals; Blood Glucose; Growth Hormone; Hyperglycemia; Male; Papio; Phentolamine; Propranolol; Shock

1974
[Drugs in shock treatment].
    Der Internist, 1971, Volume: 12, Issue:3

    Topics: Adrenal Cortex Hormones; Cardiac Output; Chlorpromazine; Digitalis Glycosides; Humans; Isoproterenol

1971
The problem of acute severe trauma and shock.
    Surgery, gynecology & obstetrics, 1971, Volume: 133, Issue:5

    Topics: Accidents; Adolescent; Aircraft; Ambulances; Arteries; Blood Pressure; Cardiac Output; Central Venou

1971
Combined adrenergic receptor blockade and circulating catecholamines in hemorrhagic shock.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1971, Volume: 3, Issue:6

    Topics: Animals; Blood Flow Velocity; Blood Pressure Determination; Carbon Dioxide; Cardiac Output; Catechol

1971
[163. Intestinal factors in shock: intestinal circulation].
    Langenbecks Archiv fur Chirurgie, 1967, Volume: 319

    Topics: Animals; Blood Flow Velocity; Blood Pressure; Chlorpromazine; Dogs; Gastrointestinal Hemorrhage; Hyp

1967
The use of phentolamine in experimental hemorrhagic shock.
    Angiology, 1970, Volume: 21, Issue:5

    Topics: Animals; Blood Pressure; Cardiac Output; Dogs; Femoral Artery; Heart Rate; Hemodynamics; Injections,

1970
The dilemma of vasopressors and vasodilators in the therapy of shock.
    Surgery, gynecology & obstetrics, 1971, Volume: 132, Issue:1

    Topics: Blood Pressure; Cardiac Output; Central Venous Pressure; Chlorpromazine; Heart Rate; Hemodynamics; H

1971
[Basic principles of shock therapy].
    Deutsche medizinische Wochenschrift (1946), 1971, Jan-22, Volume: 96, Issue:4

    Topics: Blood Transfusion; Digitalis Glycosides; Dopamine; Glucagon; Humans; Isoproterenol; Metaproterenol;

1971
[The use of sympathomimetics and sympatholytics in shock].
    Duodecim; laaketieteellinen aikakauskirja, 1971, Volume: 87, Issue:4

    Topics: Chlorpromazine; Dopamine; Humans; Isoproterenol; Metaraminol; Norepinephrine; Phenoxybenzamine; Phen

1971
[Prevention of renal artery constriction during experimental hemorrhagic shock].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1969, Apr-21, Volume: 24, Issue:15

    Topics: Animals; Chlorpromazine; Dogs; Female; Male; Norepinephrine; Phentolamine; Renal Artery Obstruction;

1969