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phentolamine and Hemorrhage, Subarachnoid

phentolamine has been researched along with Hemorrhage, Subarachnoid in 17 studies

Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.

Research Excerpts

ExcerptRelevanceReference
"These arrhythmias have responded to sympathetic blocking agents, which may also have a protective effect on subendocardial tissue in this setting."1.27Subarachnoid hemorrhage and the heart. ( Marion, DW; Segal, R; Thompson, ME, 1986)
"Phentolamine was ineffective."1.26Mechanism of cerebral arterial contraction induced by blood constituents. ( Ohta, T; Shimizu, K; Toda, N, 1980)
"Phentolamine, that is an adrenergic blocking agent, relieved the early spam remarkably, but it was less effective on the late spam."1.25[Experimental Subarachnoid hemmorrhage in dogs--effect of various drugs and sympathectomy on cerebral arterial spasm (author's transl)]. ( Noda, S, 1975)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199015 (88.24)18.7374
1990's1 (5.88)18.2507
2000's1 (5.88)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Su, CF1
Yang, YL1
Lee, MC1
Chen, HI1
Walter, P3
Neil-Dwyer, G3
Cruickshank, JM3
Toda, N1
Shimizu, K1
Ohta, T1
Furuichi, S1
Endo, S1
Haji, A1
Takeda, R1
Nisijima, M1
Takaku, A1
Doshi, B1
O'Gorman, P1
Falk, RH1
Casscells, W1
Martins, AN2
Newby, N1
Doyle, TF1
Kobrine, AI1
Ramirez, A1
Hayashi, M1
Marukawa, S1
Fujii, H1
Kitano, T1
Kobayashi, H1
Nagai, H1
Noda, S2
Mabe, H1
Yabuno, N1
Peeler, DF1
Klein, RL1
Thureson-Klein, A1
Clower, BR1
Smith, RR1
Marion, DW1
Segal, R1
Thompson, ME1
Wiley, JK1
Flamm, ES1
Yasargil, MG1
Ransohoff, J1
Smigiel, MR1
Sundt, TM1
Echlin, FA1

Reviews

1 review available for phentolamine and Hemorrhage, Subarachnoid

ArticleYear
Current concepts in the etiology and treatment of vasospasm.
    Clinical neurosurgery, 1968, Volume: 15

    Topics: Animals; Brain Edema; Cerebral Angiography; Cerebral Arteries; Cerebrovascular Circulation; Disease

1968

Trials

3 trials available for phentolamine and Hemorrhage, Subarachnoid

ArticleYear
Beneficial effects of adrenergic blockade in patients with subarachnoid haemorrhage.
    British medical journal (Clinical research ed.), 1982, Jun-05, Volume: 284, Issue:6330

    Topics: Adolescent; Adult; Aged; Aneurysm; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Comb

1982
Effect of propranolol and phentolamine on myocardial necrosis after subarachnoid haemorrhage.
    British medical journal, 1978, Oct-07, Volume: 2, Issue:6143

    Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Female; Humans; Male; Mid

1978
Beta-blockade benefits patients following a subarachnoid haemorrhage.
    European journal of clinical pharmacology, 1985, Volume: 28 Suppl

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Catecholamines; Electrocardiog

1985

Other Studies

13 other studies available for phentolamine and Hemorrhage, Subarachnoid

ArticleYear
A severe vicious cycle in uncontrolled subarachnoid hemorrhage: the effects on cerebral blood flow and hemodynamic responses upon intracranial hypertension.
    The Chinese journal of physiology, 2006, Feb-28, Volume: 49, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Cerebrovascular Circulation; Dogs; Heart Rate; Hemodynamics;

2006
Mechanism of cerebral arterial contraction induced by blood constituents.
    Journal of neurosurgery, 1980, Volume: 53, Issue:3

    Topics: Animals; Aspirin; Cerebrovascular Circulation; Cinanserin; Dogs; Female; Hemoglobins; Ischemic Attac

1980
Related changes in sympathetic activity, cerebral blood flow and intracranial pressure, and effect of an alpha-blocker in experimental subarachnoid haemorrhage.
    Acta neurochirurgica, 1999, Volume: 141, Issue:4

    Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Blood Transfusion; Cats; Cerebrovascula

1999
Effects of drugs on myocardial necrosis after subarachnoid haemorrhage.
    British medical journal, 1978, Nov-25, Volume: 2, Issue:6150

    Topics: Humans; Myocardium; Necrosis; Phentolamine; Propranolol; Subarachnoid Hemorrhage

1978
Effect of intracisternal phentolamine on cerebral blood flow after subarachnoid injection of blood.
    Journal of neurosurgery, 1976, Volume: 44, Issue:3

    Topics: Animals; Blood Pressure; Blood Transfusion, Autologous; Cerebrovascular Circulation; Cisterna Magna;

1976
[Effects of norepinephrine and phentolamine on acute intracranial hypertension].
    No to shinkei = Brain and nerve, 1976, Volume: 28, Issue:2

    Topics: Adult; Hematoma; Humans; Intracranial Aneurysm; Intracranial Pressure; Male; Middle Aged; Norepineph

1976
Experimental cerebral vasospasm. Part 2: effects of vasoactive drugs and sympathectomy on early and late spasm.
    Journal of neurosurgery, 1975, Volume: 42, Issue:4

    Topics: Animals; Circle of Willis; Disease Models, Animal; Dogs; Ischemic Attack, Transient; Isoxsuprine; Me

1975
[Experimental Subarachnoid hemmorrhage in dogs--effect of various drugs and sympathectomy on cerebral arterial spasm (author's transl)].
    No shinkei geka. Neurological surgery, 1975, Volume: 3, Issue:9

    Topics: Animals; Autonomic Agents; Cerebral Arteries; Dogs; Ischemic Attack, Transient; Isoxsuprine; Methyse

1975
Subarachnoid haemorrhage produces differential effects on transmitter kinetics at cerebral periarterial noradrenergic terminals.
    Neurological research, 1988, Volume: 10, Issue:1

    Topics: Animals; Brain; Cats; Electric Stimulation; Functional Laterality; Microscopy, Electron; Neurons; No

1988
Subarachnoid hemorrhage and the heart.
    Neurosurgery, 1986, Volume: 18, Issue:1

    Topics: Adult; Arrhythmias, Cardiac; Bibliographies as Topic; Catecholamines; Coronary Disease; Electrocardi

1986
Side effects of spasmolytic agents in the monkey. Intracisternal phenoxybenzamine and phentolamine.
    Journal of neurosurgery, 1973, Volume: 39, Issue:5

    Topics: Animals; Dose-Response Relationship, Drug; Electroencephalography; Haplorhini; Hypotension; Injectio

1973
Alteration of experimental cerebral vasospasm by adrenergic blockade.
    Journal of neurosurgery, 1972, Volume: 37, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Basilar Artery; Blood Flow Velocity; Blood Pressure; Cats; Di

1972
Comparative effectiveness of alpha-blockade and beta-stimulation in modifying experimental basilar arterial spasm.
    Journal of neurosurgery, 1974, Volume: 41, Issue:3

    Topics: Animals; Basilar Artery; Cats; Drug Evaluation, Preclinical; Ischemic Attack, Transient; Isoproteren

1974