phentolamine has been researched along with Eye Diseases in 5 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
Eye Diseases: Diseases affecting the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "1% noradrenaline or 10% phenylepherine to either a surgically sympathectomised or a guanethidine treated rabbit eye induced a transient increase in intraocular pressure (IOP), between 90 and 150 min, followed by a fall to hypotensive levels." | 3.66 | Prostaglandin mediated inflammatory changes induced by alpha-adrenoceptor stimulation in the sympathectomised rabbit eye. ( Unger, WG, 1979) |
| " Intravitreous injection of phentolamine was without effect on the intraocular pressure and resistance to outflow of aqueous humour, although such injections resulted in miosis." | 3.64 | THE ACTION OF SYMPATHOMIMETIC AMINES ON THE OUTFLOW OF AQUEOUS HUMOUR FROM THE EYE. ( EAKINS, KE; RYAN, SJ, 1964) |
| "Methysergide seems to inhibit the response, probably acting via the 5-HT1-receptors." | 1.27 | Effect of alpha-adrenergic and serotonergic blockers on the acute irritative response in the rabbit eye. ( Krootila, K; Palkama, A; Uusitalo, H, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| EAKINS, KE | 1 |
| RYAN, SJ | 1 |
| Unger, WG | 1 |
| Bengtsson, E | 1 |
| Weisse, I | 1 |
| Hoefke, W | 1 |
| Greenberg, S | 1 |
| Gaida, W | 1 |
| Stötzer, H | 1 |
| Kreuzer, H | 1 |
| Krootila, K | 1 |
| Uusitalo, H | 1 |
| Palkama, A | 1 |
5 other studies available for phentolamine and Eye Diseases
| Article | Year |
|---|---|
THE ACTION OF SYMPATHOMIMETIC AMINES ON THE OUTFLOW OF AQUEOUS HUMOUR FROM THE EYE.
Topics: Animals; Aqueous Humor; Denervation; Epinephrine; Eye Diseases; Intraocular Pressure; Isoproterenol; | 1964 |
Prostaglandin mediated inflammatory changes induced by alpha-adrenoceptor stimulation in the sympathectomised rabbit eye.
Topics: Animals; Epinephrine; Eye; Eye Diseases; Female; Guanethidine; Indomethacin; Intraocular Pressure; M | 1979 |
The difference between the influence of prostaglandin and alpha-melanocyte stimulating hormone on the blood aqueous barrier.
Topics: Animals; Aqueous Humor; Eye; Eye Diseases; Inflammation; Infrared Rays; Iris; Melanocyte-Stimulating | 1977 |
Ophthalmological and pharmacological studies after administration of clonidine in rats.
Topics: Animals; Clonidine; Cornea; Exophthalmos; Eye; Eye Diseases; Female; Male; Phentolamine; Rats; Rats, | 1978 |
Effect of alpha-adrenergic and serotonergic blockers on the acute irritative response in the rabbit eye.
Topics: Adrenergic alpha-Antagonists; Animals; Aqueous Humor; Blood Pressure; Eye Diseases; Eye Proteins; Fe | 1987 |