Page last updated: 2024-11-06

phentolamine and Edema

phentolamine has been researched along with Edema in 13 studies

Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.

Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.

Research Excerpts

ExcerptRelevanceReference
" Pretreatment with p-chlorophenylalanine, indomethacin, ibuprofen, and nimodipine attenuated the SCEP changes immediately after trauma and resulted in a marked reduction in edema formation, BSCB permeability, and blood flow changes at 5 h."3.71Assessment of spinal cord pathology following trauma using early changes in the spinal cord evoked potentials: a pharmacological and morphological study in the rat. ( Sharma, HS; Winkler, T, 2002)
"Treatment with phentolamine or saralasin failed to prevent the waning of the vasodilation during the prolonged infusion of BK into forelimbs perfused at constant flow."1.27Contribution of kininase II to the waning of vascular actions of bradykinin. ( Adamski, SW; Grega, GJ, 1988)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199011 (84.62)18.7374
1990's1 (7.69)18.2507
2000's1 (7.69)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sharma, HS1
Winkler, T1
LECOMTE, J1
CESSION-FOSSION, A1
LIBON, JC1
BACQ, ZM1
Imanishi, H1
Tomatsu, K1
Nishiyama, Y1
Murata, S1
Kamei, H1
Goldenberg, MM1
Meurer, RD1
Das, N1
Rao, YV1
Das, PK1
Bhattacharya, SK1
Macaluso, A1
McCoy, D1
Ceriani, G1
Watanabe, T1
Biltz, J1
Catania, A1
Lipton, JM1
Adamski, SW1
Grega, GJ1
Bekemeier, H1
Hirschelmann, R1
Giessler, AJ1
Somogyi, A1
Selye, H1
Green, KL1
Timsit, J1
Giroud, JP1
Dechezleprĕtre, S1
Lechat, P1
Brown, JH1
Garrett, RL1
McKinney, GR1
Lish, PM1

Other Studies

13 other studies available for phentolamine and Edema

ArticleYear
Assessment of spinal cord pathology following trauma using early changes in the spinal cord evoked potentials: a pharmacological and morphological study in the rat.
    Muscle & nerve. Supplement, 2002, Volume: 11

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents; Anti-I

2002
[ON SOME GENERAL PHARMACODYNAMIC EFFECTS OF CYSTAMINE IN THE RAT].
    Archives internationales de pharmacodynamie et de therapie, 1964, Apr-01, Volume: 148

    Topics: Adrenalectomy; Anti-Allergic Agents; Antihypertensive Agents; Bis-Trimethylammonium Compounds; Blood

1964
[Mechanism of action of certain fibrinolytic bis-tetrahydroisoquinolines: their antagonists and histamine- and 5-hydroxytryptamine-releasing effects (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1980, Volume: 76, Issue:1

    Topics: Animals; Cyproheptadine; Edema; Fibrinolysis; Fibrinolytic Agents; Histamine Release; Isoquinolines;

1980
A pharmacologic analysis of the action of platelet-activating factor in the induction of hindpaw edema in the rat.
    Prostaglandins, 1984, Volume: 28, Issue:2

    Topics: Animals; Carrageenan; Dexamethasone; Dose-Response Relationship, Drug; Edema; Hindlimb; Indomethacin

1984
Effect of centrally administered monoaminergic & cholinergic receptor antagonists on carrageenin-induced pedal edema in rats.
    Indian journal of experimental biology, 1982, Volume: 20, Issue:5

    Topics: Animals; Atropine; Carrageenan; Edema; Female; Haloperidol; Male; Methysergide; Phentolamine; Propra

1982
Antiinflammatory influences of alpha-MSH molecules: central neurogenic and peripheral actions.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1994, Volume: 14, Issue:4

    Topics: alpha-MSH; Amino Acid Sequence; Animals; Anti-Inflammatory Agents, Non-Steroidal; Atenolol; Atropine

1994
Contribution of kininase II to the waning of vascular actions of bradykinin.
    The American journal of physiology, 1988, Volume: 254, Issue:6 Pt 2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Dogs; Edem

1988
Carrageenin-induced thrombosis in rats and mice: a model for testing antithrombotic substances?
    Agents and actions, 1985, Volume: 16, Issue:5

    Topics: Animals; Carrageenan; Cyproheptadine; Dibenzylchlorethamine; Disease Models, Animal; Dose-Response R

1985
Tourniquet poditis--an experimental pedal inflammation in the rat.
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Chlorpromazine; Cyproheptadine; Depression, Chemical; Dextrans; Dibe

1969
Mechanism of the pro-inflammatory activity of sympathomimetic amines in thermic oedema of the rat paw.
    British journal of pharmacology, 1974, Volume: 50, Issue:2

    Topics: Animals; Blood Circulation; Bradykinin; Capillary Permeability; Edema; Epinephrine; Foot; Heparin; H

1974
[The anti-inflammatory action of adrenaline].
    Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 205, Issue:1

    Topics: Adrenal Glands; Adrenalectomy; Animals; Anti-Inflammatory Agents; Blood Glucose; Capillary Permeabil

1973
Inhibition of constriction-induced reactive hyperemic edema.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 139, Issue:2

    Topics: Alphaprodine; Animals; Atropine; Constriction; Edema; Epinephrine; Hexamethonium Compounds; Hindlimb

1972
Interaction of beta adrenergic blockade and certain vasodilators in dextran-induced rat paw edema.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1966, Volume: 121, Issue:2

    Topics: Animals; Dextrans; Edema; Epinephrine; Hydralazine; Phentolamine; Rats; Sympatholytics; Vasodilator

1966