Page last updated: 2024-11-06

phentolamine and Drug Hypersensitivity

phentolamine has been researched along with Drug Hypersensitivity in 8 studies

Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.

Drug Hypersensitivity: Immunologically mediated adverse reactions to medicinal substances used legally or illegally.

Research Excerpts

ExcerptRelevanceReference
"Recently it has been shown that patients with atopic rhinitis and with an allergy to house dust mites have a stronger nasal response to insufflation of histamine, methacholine and phentolamine than a control group."7.68Nasal hyper-responsiveness to histamine, methacholine and phentolamine in patients with perennial non-allergic rhinitis and in patients with infectious rhinitis. ( Dieges, PH; Gerth van Wijk, R, 1991)
"Recently it has been shown that patients with atopic rhinitis and with an allergy to house dust mites have a stronger nasal response to insufflation of histamine, methacholine and phentolamine than a control group."3.68Nasal hyper-responsiveness to histamine, methacholine and phentolamine in patients with perennial non-allergic rhinitis and in patients with infectious rhinitis. ( Dieges, PH; Gerth van Wijk, R, 1991)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19906 (75.00)18.7374
1990's1 (12.50)18.2507
2000's0 (0.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Becker, DE1
Reed, KL1
GOLLUB, MJ1
Yokoyama, M1
Kusui, A1
Sakamoto, S1
Fukuzaki, H1
Gerth van Wijk, R1
Dieges, PH1
Keller, R1
Beeger, I1
Innes, IR1
Karr, GW1
Norberg, KA1
Palmer, B1
Morrison, JM1
Fleming, WW1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy and Safety of Prilocaine 2% and Lidocaine 5% Hyperbaric Against Spinal Anesthesia in Post Cystoscopy Procedure[NCT05834647]Phase 445 participants (Anticipated)Interventional2023-08-01Not yet recruiting
Effects of Continuous Lidocaine Infusion Via Closed Chest Drainage Tube on Postoperative Analgesia for Patients Undergoing Thoracoscopic Partial Lung Resection: a Single-center Randomized Controlled Clinical Trial[NCT05901389]456 participants (Anticipated)Interventional2023-06-30Not yet recruiting
Efficacy of Postoperative Pain Control Between Transarticular VS Periartiucular Multimodal Drug Infiltration in Total Hip Arthroplasty: Double-blinded Randomized Control Trial[NCT05325671]120 participants (Anticipated)Interventional2022-04-05Not yet recruiting
The Comparison Between Dexamethasone and Morphine as an Adjuvant to Epidural Bupivacaine for Post-operative Analgesia in Lower Extremity Surgery[NCT03051022]64 participants (Actual)Interventional2016-05-01Completed
Comparative Study of the Anaesthetic Efficacy of 4% Articaine Versus 2% Mepivacaine in Mandibular Third Molar Germectomy Using Different Anaesthetic Techniques: a Split-mouth Clinical Trial[NCT04465149]50 participants (Actual)Interventional2018-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for phentolamine and Drug Hypersensitivity

ArticleYear
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012

Other Studies

7 other studies available for phentolamine and Drug Hypersensitivity

ArticleYear
MYOCARDIAL INFARCTION AFTER THE PHENTOLAMINE TEST.
    The New England journal of medicine, 1965, Jul-01, Volume: 273

    Topics: Cardiovascular Diseases; Drug Hypersensitivity; Electrocardiography; Geriatrics; Hypertension; Myoca

1965
Age-associated increments in human platelet alpha-adrenoceptor capacity. Possible mechanism for platelet hyperactivity to epinephrine in aging man.
    Thrombosis research, 1984, May-15, Volume: 34, Issue:4

    Topics: Adult; Aged; Aging; Binding, Competitive; Blood Platelets; Dihydroergotoxine; Drug Hypersensitivity;

1984
Nasal hyper-responsiveness to histamine, methacholine and phentolamine in patients with perennial non-allergic rhinitis and in patients with infectious rhinitis.
    Clinical otolaryngology and allied sciences, 1991, Volume: 16, Issue:2

    Topics: Adolescent; Adult; Aged; Child; Chronic Disease; Drug Hypersensitivity; Histamine; Humans; Methachol

1991
Increase in the sensitivity of the rat to histamine following injection with Nippostrongylus brasiliensis.
    International archives of allergy and applied immunology, 1971, Volume: 41, Issue:2

    Topics: Allergens; Animals; Blood Glucose; Cortisone; Drug Hypersensitivity; Epinephrine; Histamine; Histami

1971
Protection against induction of supersensitivity to catecholamines by cocaine.
    British journal of pharmacology, 1971, Volume: 42, Issue:4

    Topics: Acetylcholine; Animals; Catecholamines; Cats; Cocaine; Drug Hypersensitivity; Drug Synergism; Epinep

1971
Effects of noradrenaline and felypressin on cutaneous local blood flow after sympathetic denervation. A study on rats.
    Scandinavian journal of plastic and reconstructive surgery, 1972, Volume: 6, Issue:2

    Topics: Animals; Back; Catecholamines; Denervation; Drug Hypersensitivity; Felypressin; Female; Ganglia, Aut

1972
Supersensitivity of decentralized and denervated nictitating membranes to barium.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1971, Volume: 136, Issue:1

    Topics: Animals; Barium; Cats; Denervation; Drug Hypersensitivity; Nictitating Membrane; Norepinephrine; Phe

1971