phentolamine has been researched along with Diabetic Neuropathies in 5 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Therapeutic potential of agomelatine on neuropathic pain was suppressed with α-methyl-para-tyrosine methyl ester (an inhibitor of catecholamine synthesis), phentolamine (a nonselective α-adrenoceptor antagonist), and propranolol (a nonselective β-adrenoceptor antagonist) administrations." | 1.43 | Effect of subacute agomelatine treatment on painful diabetic neuropathy: involvement of catecholaminergic mechanisms. ( Aydın, TH; Can, ÖD; Demir Özkay, Ü; Turan, N, 2016) |
| "Diabetic microangiopathy is regarded as the most important pathogenic factor." | 1.27 | [Disorders of erectile potency in diabetes mellitus]. ( Floth, A; Holzmann, RM; Schramek, P, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aydın, TH | 1 |
| Can, ÖD | 1 |
| Demir Özkay, Ü | 1 |
| Turan, N | 1 |
| Vinik, AI | 1 |
| Glowniak, JV | 1 |
| Hilsted, J | 1 |
| Madsbad, S | 1 |
| Sestoft, L | 1 |
| Dunlap, ED | 1 |
| Samols, E | 1 |
| Waite, LC | 1 |
| Pfeifer, MA | 1 |
| Schramek, P | 1 |
| Holzmann, RM | 1 |
| Floth, A | 1 |
1 review available for phentolamine and Diabetic Neuropathies
| Article | Year |
|---|---|
Hormonal secretion in diabetic autonomic neuropathy.
Topics: Autonomic Nervous System; Autonomic Nervous System Diseases; Diabetic Neuropathies; Gastric Inhibito | 1982 |
4 other studies available for phentolamine and Diabetic Neuropathies
| Article | Year |
|---|---|
Effect of subacute agomelatine treatment on painful diabetic neuropathy: involvement of catecholaminergic mechanisms.
Topics: Acetamides; Animals; Blood Glucose; Catecholamines; Diabetes Mellitus, Experimental; Diabetic Neurop | 2016 |
Subcutaneous blood flow during insulin-induced hypoglycaemia: studies in juvenile diabetics with and without autonomic neuropathy and in normal subjects.
Topics: Adult; Ankle; Blood Circulation; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Neuropathies; He | 1982 |
Development of a method to determine autonomic nervous system function in the rat.
Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Autonomic Nervous System; Circadian Rhythm; Diabe | 1987 |
[Disorders of erectile potency in diabetes mellitus].
Topics: Aged; Alprostadil; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diab | 1988 |