phentolamine has been researched along with Diabetes Mellitus, Type 1 in 17 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
Diabetes Mellitus, Type 1: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
Excerpt | Relevance | Reference |
---|---|---|
"Diabetic microangiopathy is regarded as the most important pathogenic factor." | 1.27 | [Disorders of erectile potency in diabetes mellitus]. ( Floth, A; Holzmann, RM; Schramek, P, 1988) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 15 (88.24) | 18.7374 |
1990's | 1 (5.88) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (5.88) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Raikhelkar, J | 1 |
Anyanwu, A | 1 |
Gist, RS | 1 |
Somal, J | 1 |
Mechanick, JI | 1 |
Scher, C | 1 |
Scurlock, C | 1 |
Simonson, DC | 2 |
Koivisto, V | 1 |
Sherwin, RS | 1 |
Ferrannini, E | 1 |
Hendler, R | 1 |
Juhlin-Dannfelt, A | 1 |
DeFronzo, RA | 2 |
Hilsted, J | 1 |
Madsbad, S | 1 |
Sestoft, L | 1 |
Bolinder, J | 1 |
Sjöberg, S | 1 |
Arner, P | 1 |
Gerich, JE | 2 |
Lorenzi, M | 1 |
Tsalikian, E | 1 |
Karam, JH | 1 |
Sperling, MA | 1 |
Voina, S | 1 |
Campbell, PJ | 1 |
Bolli, GB | 1 |
Cryer, PE | 1 |
Bosquet, F | 1 |
Grimaldi, A | 1 |
Schramek, P | 1 |
Holzmann, RM | 1 |
Floth, A | 1 |
Castellino, P | 1 |
Cegrell, L | 1 |
Hansen, AP | 1 |
Czyzyk, A | 1 |
Ostrowski, K | 1 |
Carroll, KF | 1 |
Nestel, PJ | 1 |
Lundbaek, K | 2 |
Handwerger, S | 1 |
Roth, J | 1 |
Gorden, P | 1 |
Di Sant' Agnese, P | 1 |
Carpenter, DF | 1 |
Peter, G | 1 |
1 review available for phentolamine and Diabetes Mellitus, Type 1
Article | Year |
---|---|
[Blood glucose counter-regulation].
Topics: Adrenergic beta-Antagonists; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids; Glu | 1985 |
1 trial available for phentolamine and Diabetes Mellitus, Type 1
Article | Year |
---|---|
The effect of adrenergic receptor blockade on the exercise-induced serum growth hormone rise in normals and juvenile diabetics.
Topics: Adolescent; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Blood Glucose; Clinica | 1971 |
15 other studies available for phentolamine and Diabetes Mellitus, Type 1
Article | Year |
---|---|
Pheochromocytoma presenting as severe biventricular failure requiring insertion of a biventricular assist device.
Topics: Acidosis; Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Diabetes Mellitus, Type 1; Diabetic | 2010 |
Adrenergic blockade alters glucose kinetics during exercise in insulin-dependent diabetics.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Humans; I | 1984 |
Subcutaneous blood flow during insulin-induced hypoglycaemia: studies in juvenile diabetics with and without autonomic neuropathy and in normal subjects.
Topics: Adult; Ankle; Blood Circulation; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Neuropathies; He | 1982 |
Stimulation of adipose tissue lipolysis following insulin-induced hypoglycaemia: evidence of increased beta-adrenoceptor-mediated lipolytic response in IDDM.
Topics: Adipose Tissue; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Analysis of Varian | 1996 |
Studies on the mechanism of epinephrine-induced hyperglycemia in man. Evidence for participation of pancreatic glucagon secretion.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Drug Synergism; Epinephrine; Fatty Acids, Nonesteri | 1976 |
Effect of adrenergic blockade on glucagon and growth hormone secretion in normal and diabetic children.
Topics: Adolescent; Arginine; Blood Glucose; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Growth Horm | 1975 |
Pathogenesis of the dawn phenomenon in patients with insulin-dependent diabetes mellitus. Accelerated glucose production and impaired glucose utilization due to nocturnal surges in growth hormone secretion.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Growth Hormone; Humans; Hype | 1985 |
[Disorders of erectile potency in diabetes mellitus].
Topics: Aged; Alprostadil; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diab | 1988 |
Adrenergic modulation of potassium metabolism during exercise in normal and diabetic humans.
Topics: Adult; Bicarbonates; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Humans; Insulin; Kine | 1987 |
Phentolamine and juvenile diabetes.
Topics: Adolescent; Diabetes Mellitus, Type 1; Humans; Insulin; Insulin Secretion; Male; Phentolamine | 1972 |
Reactivity of the veins in diabetes.
Topics: Adolescent; Adult; Cold Temperature; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Ethanolamines | 1972 |
Diurnal variation in glucose tolerance and in insulin secretion in man.
Topics: Administration, Oral; Adolescent; Adult; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; | 1973 |
Growth hormoe and diabetic angiopathy.
Topics: Adolescent; Blood Glucose; Capillary Permeability; Child; Diabetes Mellitus; Diabetes Mellitus, Type | 1973 |
Glucose intolerance in cystic fibrosis.
Topics: Adolescent; Adult; Blood Glucose; Child; Cystic Fibrosis; Diabetes Mellitus; Diabetes Mellitus, Type | 1969 |
Growth hormone and diabetic angiopathy.
Topics: Adolescent; Adult; Blood Glucose; Capillary Resistance; Diabetes Mellitus, Type 1; Diabetic Angiopat | 1971 |