phentolamine has been researched along with Decerebrate Posturing in 40 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Kynuramine was found to release cardiac catecholamines and to act as a weak partial agonist on vascular alpha-adrenoceptors." | 1.27 | Cardiovascular actions of kynuramine and 5-hydroxykynuramine in pithed rats. ( Charlton, KG; Clarke, DE; Hamed, AT; Johnson, TD, 1983) |
| "Atropine treatment decreased, and phentolamine administration elicited a greater absolute and percent change increase in insulin levels of decerebrate rats." | 1.27 | Pre- and postabsorptive insulin secretion in chronic decerebrate rats. ( Berridge, KC; Flynn, FW; Grill, HJ, 1986) |
| "Pretreatment with reserpine prevented the restoration of blood pressure by all drugs." | 1.27 | The effects of meptazinol in comparison with pentazocine, morphine and naloxone in a rat model of anaphylactic shock. ( Paciorek, PM; Todd, MH; Waterfall, JF, 1985) |
| " The dose-response curve to guanfacine for increase in blood pressure was shifted in a parallel fashion to the right by 1 mg/kg of yohimbine, an alpha 2-antagonist and by 1 mg/kg of phentolamine, a nonselective alpha 1- and alpha 2-antagonist." | 1.26 | [Effects of guanfacine on pre- and postsynaptic alpha-adrenoceptors studied in comparison with those of clonidine]. ( Chin, W; Imai, S; Nakagawa, Y, 1982) |
| "Pretreatment with phentolamine significantly attenuated the constriction and augmentation of vasomotion." | 1.26 | Microvascular response to blockade of prostaglandin synthesis in rat skeletal muscle. ( Faber, JE; Harris, PD; Joshua, IG, 1982) |
| "Pretreatment with piperoxane (10 mg/kg) antagonized this effect but pretreatment with phentolamine (10 mg/kg) did not." | 1.26 | Effects of clonidine on habituation and sensitization of acoustic startle in normal, decerebrate and locus coeruleus lesioned rats. ( Aghajanian, GK; Cedarbaum, JM; Davis, M; Gendelman, DS, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (67.50) | 18.7374 |
| 1990's | 13 (32.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SALMOIRAGHI, GC | 1 |
| BLOOM, FE | 1 |
| COSTA, E | 1 |
| Nakagawa, Y | 1 |
| Chin, W | 1 |
| Imai, S | 1 |
| Charlton, KG | 1 |
| Johnson, TD | 1 |
| Hamed, AT | 1 |
| Clarke, DE | 1 |
| Gokin, AP | 1 |
| Vankov, A | 1 |
| Karpukhina, MV | 1 |
| Pavlasek, Iu | 1 |
| Faber, JE | 1 |
| Harris, PD | 1 |
| Joshua, IG | 1 |
| Tadepalli, AS | 2 |
| Prasad, CM | 1 |
| Gaw, AJ | 1 |
| Hills, DM | 1 |
| Spraggs, CF | 1 |
| Ono, H | 1 |
| Fukushima, C | 1 |
| Fukuda, H | 1 |
| Moorman, SJ | 1 |
| Whalen, LR | 1 |
| Satoh, K | 1 |
| Grassi, C | 1 |
| Deriu, F | 1 |
| Passatore, M | 1 |
| McCafferty, GP | 1 |
| Naselsky, DP | 1 |
| Hieble, JP | 2 |
| Mediavilla, A | 1 |
| Feria, M | 1 |
| Fernández, JF | 1 |
| Cagigas, P | 1 |
| Pazos, A | 1 |
| Flórez, J | 1 |
| Kobinger, W | 2 |
| Pichler, L | 2 |
| Davis, M | 1 |
| Cedarbaum, JM | 1 |
| Aghajanian, GK | 1 |
| Gendelman, DS | 1 |
| Tikal, K | 1 |
| Mills, E | 1 |
| Schanberg, SM | 1 |
| Slavik, KJ | 1 |
| Szilagyi, JE | 1 |
| Kiehn, O | 1 |
| Hultborn, H | 1 |
| Conway, BA | 1 |
| Pawlak, D | 1 |
| Malinowska, B | 1 |
| Buczko, W | 1 |
| Rabloczky, G | 1 |
| Jaszlits, L | 1 |
| Horváth, E | 1 |
| Vollmer, RR | 1 |
| Meyers-Schoy, SA | 1 |
| Marinelli, RR | 1 |
| Willette, RN | 1 |
| Sauermelch, CF | 1 |
| Mizutani, M | 1 |
| Neya, T | 1 |
| Nakayama, S | 1 |
| Kurtz, A | 1 |
| Della Bruna, R | 1 |
| Pratz, J | 1 |
| Cavero, I | 1 |
| Hanazuka, M | 1 |
| Horii, D | 1 |
| Mizogami, S | 1 |
| Giuliani, S | 1 |
| Maggi, CA | 1 |
| Meli, A | 1 |
| Hyman, AL | 1 |
| Dempesy, CW | 1 |
| Fontana, C | 1 |
| Richardson, DE | 1 |
| Rieck, RW | 1 |
| Kadowitz, PJ | 1 |
| Flynn, FW | 1 |
| Berridge, KC | 1 |
| Grill, HJ | 1 |
| Yajima, T | 1 |
| Urano, T | 1 |
| Nakamura, K | 2 |
| Matsuura, A | 1 |
| Himori, N | 1 |
| Paciorek, PM | 1 |
| Todd, MH | 1 |
| Waterfall, JF | 1 |
| Hicks, R | 1 |
| Sackeyfio, AC | 1 |
| Frederickson, RC | 1 |
| Jordan, LM | 1 |
| Phillis, JW | 1 |
| Kadzielawa, K | 1 |
| Widy-Tyszkiewicz, E | 1 |
| Yamamoto, J | 1 |
| Sekiya, A | 1 |
| Hirano, H | 1 |
| Inoue, Y | 1 |
| Tanami, J | 1 |
| Cheymol, J | 1 |
| Bourillet, F | 1 |
| Roch-Arveiller, M | 1 |
| Heckle, J | 1 |
| Gillis, RA | 1 |
| Quest, JA | 1 |
| Standaert, FG | 1 |
| Thuránszky, K | 1 |
40 other studies available for phentolamine and Decerebrate Posturing
| Article | Year |
|---|---|
ADRENERGIC MECHANISMS IN RABBIT OLFACTORY BULB.
Topics: Adrenergic Agents; Atropine; Brain; Chlorisondamine; Decerebrate State; Dopamine; Electrophoresis; H | 1964 |
[Effects of guanfacine on pre- and postsynaptic alpha-adrenoceptors studied in comparison with those of clonidine].
Topics: Adrenalectomy; Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Clonidine; Decerebrate S | 1982 |
Cardiovascular actions of kynuramine and 5-hydroxykynuramine in pithed rats.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Brain; Cerebral Cortex; Decerebrate St | 1983 |
[Effect of bulbar microinjections of noradrenaline, isoproterenol and phentolamine on the spino-bulbo-spinal reflex in the cat].
Topics: Animals; Cats; Decerebrate State; Isoproterenol; Locus Coeruleus; Microinjections; Neural Pathways; | 1984 |
Microvascular response to blockade of prostaglandin synthesis in rat skeletal muscle.
Topics: Animals; Arteries; Arterioles; Blood Pressure; Decerebrate State; Heart Rate; Indomethacin; Male; Mu | 1982 |
Depression of reflex vagal bradycardia by a central action of phentolamine in the spinal cat.
Topics: Animals; Blood Pressure; Cats; Decerebrate State; Female; Heart Rate; Injections, Intraventricular; | 1982 |
Characterization of the receptors and mechanisms involved in the cardiovascular actions of sCCK-8 in the pithed rat.
Topics: Adrenalectomy; Adrenergic Agents; Animals; Benzodiazepinones; Blood Pressure; Bradycardia; Cholecyst | 1995 |
Effect of the centrally acting muscle relaxant tizanidine on spinal reflexes: involvement of descending noradrenergic systems.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-A | 1993 |
A model system to determine the effects of specific neurotransmitters on segmental reflexes in the spinal cord of the rat.
Topics: Animals; Clonidine; Decerebrate State; Dopamine; Electromyography; Electrophysiology; Female; Hindli | 1993 |
[Pontine control of the internal urethral sphincter activity on decerebrate dogs].
Topics: Animals; Decerebrate State; Dogs; Electric Stimulation; Electromyography; Female; Hexamethonium; Hex | 1993 |
Effect of sympathetic nervous system activation on the tonic vibration reflex in rabbit jaw closing muscles.
Topics: Animals; Autonomic Denervation; Decerebrate State; Electric Stimulation; Electromyography; Heart Rat | 1993 |
Characterization of postjunctional alpha-adrenoceptors in the pithed mouse.
Topics: 3T3 Cells; Adrenergic alpha-Antagonists; Animals; Azepines; Binding, Competitive; Blood Pressure; CH | 1999 |
The stimulatory action of d-amphetamine on the respiratory centre, and its mediation by a central alpha-adrenergic mechanism.
Topics: Anesthesia; Animals; Decerebrate State; Dextroamphetamine; Drug Interactions; Hemodynamics; Male; Ph | 1979 |
The central modulatory effect of clonidine on the cardiodepressor reflex after suppression of synthesis and storage of noradrenaline.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Animals; Blood Pressure; Brain; Clonidine; Decerebrate | 1975 |
Effects of clonidine on habituation and sensitization of acoustic startle in normal, decerebrate and locus coeruleus lesioned rats.
Topics: Acoustic Stimulation; Animals; Cerebral Ventricles; Clonidine; Decerebrate State; Drug Interactions; | 1977 |
The effect of noradrenaline on the ECoG on the preparation encephalĕ isolé of rats.
Topics: Animals; Cerebral Cortex; Decerebrate State; Electroencephalography; Norepinephrine; Phentolamine; R | 1977 |
Depression and enhancement of baroreceptor pressor response in cats after intracerebroventricular injection of noradrenergic blocking agents: dependence on supracollicular areas of the brain.
Topics: Animals; Arterial Occlusive Diseases; Bradycardia; Carotid Artery Diseases; Cats; Decerebrate State; | 1976 |
Naloxone-induced bradycardia in pithed rats: evidence for an interaction with the peripheral sympathetic nervous system and alpha-2 adrenoceptors.
Topics: Animals; Atropine; Brimonidine Tartrate; Decerebrate State; Dose-Response Relationship, Drug; Heart | 1992 |
Spinal locomotor activity in acutely spinalized cats induced by intrathecal application of noradrenaline.
Topics: Animals; Cats; Decerebrate State; Injections, Intravenous; Levodopa; Locomotion; Motor Neurons; Nore | 1992 |
Cardiovascular effects of acetaldehyde in pithed rats.
Topics: Acetaldehyde; Animals; Blood Pressure; Cardiovascular System; Decerebrate State; Heart Rate; Male; P | 1992 |
GYKI-12743 a new postsynaptic vascular alpha-adrenoceptor antagonist.
Topics: Adrenergic alpha-Antagonists; Animals; Azepines; Blood Pressure; Clonidine; Decerebrate State; Dioxa | 1991 |
Mechanisms involved in angiotensin II induced increases in cardiac output in pithed rats.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiac Output; Decerebrate State; Male; Nadolol; Phentolam | 1991 |
Sympathetic regulation of cutaneous circulation in the rat.
Topics: Adrenal Medulla; Animals; Blood Pressure; Decerebrate State; Dimethylphenylpiperazinium Iodide; Dose | 1991 |
Capsaicin-sensitive afferents activate a sympathetic intestinointestinal inhibitory reflex in dogs.
Topics: Afferent Pathways; Animals; Capsaicin; Decerebrate State; Dogs; Electric Stimulation; Female; Inject | 1990 |
Rat juxtaglomerular cells are endowed with DA-1 dopamine receptors mediating renin release.
Topics: Animals; Benzazepines; Blood Pressure; Decerebrate State; Dopamine; Fenoldopam; In Vitro Techniques; | 1988 |
[Alpha-adrenoceptor blocking action of terazosin].
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Aorta; Decerebrate State; Heart Rate | 1986 |
Capsaicin-sensitive afferents in the rat urinary bladder activate a spinal sympathetic cardiovascular reflex.
Topics: Animals; Capsaicin; Decerebrate State; Electric Stimulation; Hemodynamics; Hexamethonium Compounds; | 1988 |
Pulmonary vascular responses to forebrain stimulation in the cat.
Topics: Animals; Cats; Decerebrate State; Diencephalon; Electric Stimulation; Female; Freezing; Histamine An | 1988 |
Pre- and postabsorptive insulin secretion in chronic decerebrate rats.
Topics: Animals; Atropine; Body Weight; Brain Stem; Decerebrate State; Glucose; Hypothalamus; Insulin; Insul | 1986 |
Cerebral vasodilating and vasospasmolytic action of the cerebral circulation improver 6,7-dimethoxy-1-(3,4-dimethoxybenzyl)-4-([4-(2-methoxyphenyl)-1- piperazinyl]methyl)isoquinoline in experimental animals.
Topics: Animals; Brain Chemistry; Cats; Cerebrovascular Circulation; Decerebrate State; Dogs; Female; Hypert | 1987 |
The effects of meptazinol in comparison with pentazocine, morphine and naloxone in a rat model of anaphylactic shock.
Topics: Anaphylaxis; Animals; Azepines; Blood Pressure; Decerebrate State; Electric Stimulation; Female; Hea | 1985 |
An interaction between exogenously administered anaphylatoxin and histamine in the guinea-pig.
Topics: Adrenalectomy; Anaphylaxis; Animals; Blood Pressure; Bronchi; Decerebrate State; Drug Interactions; | 1972 |
A reappraisal of the actions of noradrenaline and 5-hydroxytryptamine on cerebral cortical neurons.
Topics: Action Potentials; Adrenergic beta-Antagonists; Anesthesia; Animals; Cats; Cerebral Cortex; Creatini | 1972 |
Evidence for direct alpha-adrenoceptor stimulation of effector neurons in cardiovascular centers by clonidine.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Angiotensin II; Animals; Blood Pressure; Card | 1974 |
The influence of various pharmacological agents on the desynchronization produced by DOPA in the cerveau isolé preparation.
Topics: Animals; Cats; Chlorpromazine; Decerebrate State; Dihydroxyphenylalanine; Disulfiram; Electroencepha | 1970 |
On the pressor action of propranolol in the rat.
Topics: Adrenalectomy; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Decerebrate State; Female; Hea | 1969 |
[Studies on the mode of actions of carbon monoxide. 3. The central action of carbon monoxide].
Topics: Adrenergic alpha-Antagonists; Animals; Blood Glucose; Blood Pressure; Carbon Monoxide; Carbon Monoxi | 1971 |
[The cardiovascular action of the venoms of 3 North African scorpions (Androctonus australis, Leiurus quinquestriatus, Buthus occitanus) and 2 toxins extracted from one of them].
Topics: Animals; Autonomic Nervous System; Blood Pressure; Catecholamines; Cats; Decerebrate State; Ganglia, | 1974 |
Depression by reflexes of the pressor and cardiotoxic responses to ouabain.
Topics: Animals; Atropine; Blood Pressure; Buffers; Cardiovascular System; Cats; Cordotomy; Decerebrate Stat | 1969 |
The role of the central nervous system on the action of epinephrine and adrenolytic drugs.
Topics: Animals; Blood Pressure; Bradycardia; Cats; Central Nervous System; Chlorpromazine; Decerebrate Stat | 1966 |