phentolamine has been researched along with Cranial Nerve Diseases in 1 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
Cranial Nerve Diseases: Disorders of one or more of the twelve cranial nerves. With the exception of the optic and olfactory nerves, this includes disorders of the brain stem nuclei from which the cranial nerves originate or terminate.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Because PM had not been approved previously for submucosal administration, 2 Good Laboratory Practices (GLP) studies in dogs designed to investigate systemic toxicity and the local effects of single and repeated dosing of OraVerse on the inferior alveolar nerve and branches of the superior alveolar nerve and adjacent soft tissues after local administration were conducted." | 1.35 | Local and systemic toxicity of intraoral submucosal injections of phentolamine mesylate (OraVerse). ( Rutherford, B; Thake, D; Zeller, JR, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rutherford, B | 1 |
| Zeller, JR | 1 |
| Thake, D | 1 |
1 other study available for phentolamine and Cranial Nerve Diseases
| Article | Year |
|---|---|
Local and systemic toxicity of intraoral submucosal injections of phentolamine mesylate (OraVerse).
Topics: Adrenergic alpha-Antagonists; Anesthetics, Local; Animals; Cranial Nerve Diseases; Dogs; Hematocrit; | 2009 |