phentolamine has been researched along with Coronary Vasospasm in 12 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
Coronary Vasospasm: Spasm of the large- or medium-sized coronary arteries.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In 10 cases of Prinzmetal's angina in which episodes of myocardial ischemia were easily and reproducibly induced by hyperventilation, this test was performed 111 times, 41 times under control conditions and 70 times during treatment with one or more of the following drugs: phentolamine, isosorbide dinitrate, propranolol, verapamil, nifedipine and amiodarone." | 3.66 | The hyperventilation test as a method for developing successful therapy in Prinzmetal's angina. ( Araujo, LI; Crosatto, JR; Dyszel, E; Girotti, LA; Kaski, JC; Messuti, H; Rivas, CA; Rosenbaum, MB; Vetulli, HD, 1982) |
| "Yohimbine was completely effective for the restoration of normal ST segment." | 1.27 | Significant role of alpha 2-adrenoceptors in coronary artery spasm. ( Ito, I; Kakihana, M; Noda, H; Ohtsuka, S; Sugishita, Y, 1985) |
| "Pretreatment with phentolamine prevented the increase in CVR and the elevation in ST segment." | 1.26 | Coronary spasm produced by picrotoxin in cats. ( Gillis, RA; Pearle, DL; Segal, SA, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (91.67) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weber, S | 1 |
| Chapsal, J | 1 |
| Pipeau, C | 1 |
| Degeorges, M | 1 |
| Segal, SA | 1 |
| Pearle, DL | 1 |
| Gillis, RA | 1 |
| Chierchia, S | 1 |
| Davies, G | 1 |
| Berkenboom, G | 1 |
| Crea, F | 1 |
| Crean, P | 1 |
| Maseri, A | 1 |
| Yasue, H | 2 |
| Omote, S | 1 |
| Takizawa, A | 2 |
| Nagao, M | 2 |
| Bernadet, P | 1 |
| Marco, J | 1 |
| Alibelli, MJ | 1 |
| Sidorenko, BA | 1 |
| Shevchenko, OP | 1 |
| Alegría, E | 1 |
| Barba, J | 1 |
| Arcas, R | 1 |
| Martín Trenor, A | 1 |
| Llorens, R | 1 |
| Malpartida, F | 1 |
| Girotti, LA | 1 |
| Crosatto, JR | 1 |
| Messuti, H | 1 |
| Kaski, JC | 1 |
| Dyszel, E | 1 |
| Rivas, CA | 1 |
| Araujo, LI | 1 |
| Vetulli, HD | 1 |
| Rosenbaum, MB | 1 |
| Mizuyama, K | 1 |
| Sato, S | 1 |
| Okubo, N | 1 |
| Naito, H | 1 |
| Shepherd, JT | 1 |
| Vanhoutte, PM | 1 |
| Kakihana, M | 1 |
| Noda, H | 1 |
| Ohtsuka, S | 1 |
| Sugishita, Y | 1 |
| Ito, I | 1 |
| Nishida, S | 1 |
| Horie, M | 1 |
| Kubota, J | 1 |
6 reviews available for phentolamine and Coronary Vasospasm
| Article | Year |
|---|---|
[Alpha-blockers and treatment of coronary artery vasospasm].
Topics: Adrenergic alpha-Antagonists; Alkalosis; Coronary Vasospasm; Humans; Male; Middle Aged; Nicergoline; | 1983 |
Coronary arterial spasm in ischemic heart disease and its pathogenesis. A review.
Topics: Angina Pectoris, Variant; Animals; Arteriosclerosis; Autonomic Nervous System; Calcium; Calcium Chan | 1983 |
[Treatment of coronary artery vasospasm during coronary arteriography].
Topics: Calcium; Cardiac Catheterization; Coronary Angiography; Coronary Vasospasm; Humans; Iatrogenic Disea | 1983 |
[Angiospastic angina pectoris].
Topics: Angina Pectoris; Angina Pectoris, Variant; Atropine; Calcium Channel Blockers; Coronary Angiography; | 1983 |
[Treatment of coronary arterial spasm].
Topics: Amiodarone; Coronary Vasospasm; Denervation; Diltiazem; Humans; Isosorbide Dinitrate; Myocardial Rev | 1982 |
Spasm of the coronary arteries: causes and consequences (the scientist's viewpoint).
Topics: Adrenergic beta-Agonists; Animals; Cats; Cholinergic Fibers; Coronary Disease; Coronary Vasospasm; C | 1985 |
1 trial available for phentolamine and Coronary Vasospasm
| Article | Year |
|---|---|
alpha-Adrenergic receptors and coronary spasm: an elusive link.
Topics: Adult; Aged; Blood Pressure; Cold Temperature; Coronary Vasospasm; Electrocardiography; Female; Hear | 1984 |
5 other studies available for phentolamine and Coronary Vasospasm
| Article | Year |
|---|---|
Coronary spasm produced by picrotoxin in cats.
Topics: Animals; Cats; Coronary Vasospasm; Female; Male; Phentolamine; Picrotoxin; Receptors, Adrenergic, al | 1981 |
The hyperventilation test as a method for developing successful therapy in Prinzmetal's angina.
Topics: Adult; Amiodarone; Angina Pectoris, Variant; Coronary Vasospasm; Diagnosis, Differential; Electrocar | 1982 |
Spinal anesthesia attenuates myocardial ischemia during coronary artery spasm induced by intraaortic methacholine in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia, Sp | 1995 |
Significant role of alpha 2-adrenoceptors in coronary artery spasm.
Topics: Animals; Clonidine; Coronary Angiography; Coronary Vasospasm; Coronary Vessels; Dogs; Electrocardiog | 1985 |
Role of coronary spasm in different anginal syndromes.
Topics: Angina Pectoris; Angina Pectoris, Variant; Angiography; Circadian Rhythm; Coronary Vasospasm; Diltia | 1985 |