phentolamine has been researched along with Compensatory Hyperinsulinemia in 6 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
Compensatory Hyperinsulinemia: A GLUCOSE-induced HYPERINSULINEMIA, a marker of insulin-resistant state. It is a mechanism to compensate for reduced sensitivity to insulin.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Moreover, the hyperinsulinemia is mediated in part by prostaglandins just like the well-studied febrile response." | 1.28 | Central interleukin 1-elicited hyperinsulinemia is mediated by prostaglandins but not autonomics. ( Cornell, RP, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stich, V | 1 |
| Pelikanova, T | 1 |
| Wohl, P | 1 |
| Sengenès, C | 1 |
| Zakaroff-Girard, A | 1 |
| Lafontan, M | 1 |
| Berlan, M | 1 |
| Inoue, S | 1 |
| Mullen, YS | 1 |
| Bray, GA | 1 |
| Filkins, JP | 1 |
| Hoffman, RP | 1 |
| Sinkey, CA | 1 |
| Dopp, JM | 1 |
| Phillips, BG | 1 |
| Cornell, RP | 1 |
| Misbin, RI | 1 |
| Edgar, PJ | 1 |
| Lockwood, DH | 1 |
2 trials available for phentolamine and Compensatory Hyperinsulinemia
| Article | Year |
|---|---|
Activation of alpha2-adrenergic receptors blunts epinephrine-induced lipolysis in subcutaneous adipose tissue during a hyperinsulinemic euglycemic clamp in men.
Topics: Adipose Tissue; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adult; Epinephrine; Glucose | 2003 |
Systemic and local adrenergic regulation of muscle glucose utilization during hypoglycemia in healthy subjects.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Arteries; Blood Flow Velocity; Blo | 2002 |
4 other studies available for phentolamine and Compensatory Hyperinsulinemia
| Article | Year |
|---|---|
Hyperinsulinemia in rats with hypothalamic obesity: effects of autonomic drugs and glucose.
Topics: Animals; Atropine; Epinephrine; Female; Glucose; Hyperinsulinism; Isoproterenol; Obesity; Phentolami | 1983 |
Effect of phentolamine on insulin levels and insulin responsiveness in endotoxicosis.
Topics: Animals; Blood Glucose; Endotoxins; Glucose; Hyperinsulinism; Hypoglycemia; In Vitro Techniques; Ins | 1982 |
Central interleukin 1-elicited hyperinsulinemia is mediated by prostaglandins but not autonomics.
Topics: Acetophenones; Adrenocorticotropic Hormone; Animals; Atropine; Autonomic Nervous System; Body Temper | 1989 |
Adrenergic regulation of insulin secretion during fasting in normal subjects.
Topics: Adrenergic alpha-Antagonists; Adult; Autonomic Nervous System; Blood Glucose; Catecholamines; Fastin | 1970 |