phentolamine has been researched along with Central Hypothyroidism in 19 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In order to find out whether similar changes exist in the central nervous system, we investigated adrenoceptor-mediated responses in the rat brain cortex during propylthiouracil-induced hypothyroidism." | 3.66 | Effects of thyroid hormone deficiency on pre- and postsynaptic noradrenergic mechanisms in the rat cerebral cortex. ( Brodde, OE; Gross, G; Schümann, HJ, 1980) |
| "Clonidine did not cause any inotropic change in the euthyroid rat atrium." | 1.27 | Changes in the effects of clonidine on left atrium and hindlimb vasculature of rats in various thyroid states. A study of the responsiveness of alpha 2-adrenoceptors in the cardiovascular system. ( Nakashima, M; Oguro, K; Ohguchi, S; Sotobata, I, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (94.74) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ohguchi, S | 1 |
| Sotobata, I | 1 |
| Oguro, K | 1 |
| Nakashima, M | 3 |
| Simpson, WW | 1 |
| McNeill, JH | 1 |
| Gross, G | 1 |
| Brodde, OE | 1 |
| Schümann, HJ | 1 |
| Hirano, A | 1 |
| Hashimoto, H | 2 |
| Storm, H | 1 |
| Van Hardeveld, C | 1 |
| Kassenaar, AA | 1 |
| Lee, S | 1 |
| Ohga, Y | 1 |
| Tachibana, H | 1 |
| Syuu, Y | 1 |
| Ito, H | 1 |
| Harada, M | 1 |
| Suga, H | 1 |
| Takaki, M | 1 |
| Grill, V | 1 |
| Rosenquist, U | 1 |
| Hagino, Y | 1 |
| Shigei, T | 1 |
| Popovic, WJ | 1 |
| Brown, JE | 1 |
| Adamson, JW | 1 |
| Okajima, F | 1 |
| Ui, M | 1 |
| Massara, F | 1 |
| Camanni, F | 1 |
| Vergano, V | 1 |
| Belforte, L | 1 |
| Molinatti, GM | 1 |
| Malbon, CC | 1 |
| Li, S | 1 |
| Fain, JN | 1 |
| Niho, T | 1 |
| Noguchi, A | 1 |
| Jett, PA | 1 |
| Gold, AH | 1 |
| Kunos, G | 1 |
| Vermes-Kunos, I | 1 |
| Nickerson, M | 1 |
| Rosenqvist, U | 3 |
| Winkelmann, W | 1 |
| Efendić, S | 1 |
| Jereb, B | 1 |
| Ostman, J | 1 |
19 other studies available for phentolamine and Central Hypothyroidism
| Article | Year |
|---|---|
Changes in the effects of clonidine on left atrium and hindlimb vasculature of rats in various thyroid states. A study of the responsiveness of alpha 2-adrenoceptors in the cardiovascular system.
Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Heart Atria; Hindlimb; Hypothyroidism; In Vitr | 1984 |
Effect of adrenergic agonists on tension development and rate in atria from euthyroid and hypothyroid rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Heart Atria; Heart Rate; Hypothyro | 1980 |
Effects of thyroid hormone deficiency on pre- and postsynaptic noradrenergic mechanisms in the rat cerebral cortex.
Topics: Animals; Cerebral Cortex; Clonidine; Cyclic AMP; Dose-Response Relationship, Drug; Hypothyroidism; I | 1980 |
Influence of hypothyroid status on dopamine-induced positive chronotropic and inotropic effects on isolated rat atria.
Topics: Animals; Dopamine; Heart Rate; Hypothyroidism; In Vitro Techniques; Male; Myocardial Contraction; Ph | 1982 |
The influence of hypothyroidism on the adrenergic stimulation of glycogenolysis in perfused rat liver.
Topics: Animals; Calcium; Glucose-6-Phosphate; Glucosephosphates; Hypothyroidism; Lactates; Lactic Acid; Liv | 1984 |
Effects of myosin isozyme shift on curvilinearity of the left ventricular end-systolic pressure-volume relation of In situ rat hearts.
Topics: Animals; Antihypertensive Agents; Cardiotonic Agents; Dobutamine; Dogs; Guanethidine; Heart; Heart V | 1998 |
Accumulation of cyclic AMP in hypothyroidism. Decreased sensitivity to norepinephrine in rat adipocytes.
Topics: Adipose Tissue; Animals; Cyclic AMP; Epididymis; Hypothyroidism; Male; Norepinephrine; Phentolamine; | 1975 |
Effect of adrenergic agonists on the cyclic AMP level in the liver and heart from normal and hypothyroid rats.
Topics: Adrenalectomy; Animals; Cyclic AMP; Heart; Hypothyroidism; Liver; Male; Methoxamine; Myocardium; Phe | 1976 |
Modulation of in vitro erythropoiesis. Studies with euthyroid and hypothyroid dogs.
Topics: Adenylyl Cyclases; Animals; Colony-Forming Units Assay; Dogs; Erythropoiesis; Hypothyroidism; In Vit | 1979 |
Metabolism of glucose in hyper- and hypo-thyroid rats in vivo. Relation of catecholamine actions to thyroid activity in controlling glucose turnover.
Topics: Animals; Blood Glucose; Catecholamines; Epinephrine; Hydroxydopamines; Hyperthyroidism; Hypothyroidi | 1979 |
Inhibition of thyrotropin and prolactin secretion by dopamine in man.
Topics: Acromegaly; Adult; Aged; Dopamine; Endocrine System Diseases; Female; Galactorrhea; Humans; Hypothyr | 1978 |
Hormonal activation of glycogen phosphorylase in hepatocytes from hypothyroid rats.
Topics: Animals; Epinephrine; Female; Hypothyroidism; In Vitro Techniques; Isoproterenol; Liver; Phentolamin | 1978 |
Effects of 2-[(5-chloro-2-methoxyphenyl) azo]-1H-imidazole (M6434) on alpha adrenergic receptors.
Topics: Animals; Arteries; Dogs; Heart; Hypothyroidism; Imidazoles; In Vitro Techniques; Male; Muscle, Smoot | 1987 |
cAMP-independent stimulation of glycogen phosphorylase in newborn rat hepatocytes.
Topics: Angiotensin II; Animals; Animals, Newborn; Calcimycin; Cyclic AMP; Dose-Response Relationship, Drug; | 1985 |
Effects of thyroid state on adrenoceptor properties.
Topics: Adrenergic Agonists; Animals; Hypothyroidism; In Vitro Techniques; Isoproterenol; Male; Myocardium; | 1974 |
Inhibition of noradrenaline-induced lipolysis in hypothyroid subjects by increased -adrenergic responsiveness. An effect mediated through the reduction of cyclic AMP levels in adipose tissue.
Topics: Adipose Tissue; Adult; Aged; Cyclic AMP; Female; Humans; Hypothyroidism; In Vitro Techniques; Lipid | 1972 |
Noradrenaline-induced lipolysis in subcutaneous adipose tissue from hypothyroid subjects. The relation of noradrenaline response to the degree and duration of the disease.
Topics: Adipose Tissue; Adult; Age Factors; Aged; Body Weight; Cholesterol; Cyclic AMP; Female; Glycerol; Hu | 1972 |
[Diagnosis and immediate therapy of the endocrine crisis].
Topics: Adrenal Insufficiency; Diabetic Coma; Emergencies; Endocrine System Diseases; Glucose; Humans; Hydro | 1970 |
Influence of the hypothyroid state on lipolysis in human adipose tissue in vitro. Hypothyroid state and lipolysis.
Topics: Adenine Nucleotides; Adipose Tissue; Adult; Aged; Female; Glycerol; Humans; Hypothyroidism; In Vitro | 1971 |