phentolamine has been researched along with Bronchial Spasm in 13 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
Bronchial Spasm: Spasmodic contraction of the smooth muscle of the bronchi.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fifteen patients suffering from asthma received inhalations of phentolamine, albuterol (salbutamol), a combination of phentolamine and albuterol, and placebo, in a single-blind fashion; the changes in the pulmonary function tests were recorded over a three-hour period." | 5.05 | Comparison between an alpha-adrenergic antagonist and a beta 2-adrenergic agonist in bronchial asthma. ( Molho, MI; Shiner, RJ, 1983) |
| " To evaluate the role of alpha-adrenergic activity in the development of bronchoconstriction during airway cooling, we examined the effects of alpha-adrenergic blockade with phentolamine on bronchospasm induced by exercise and isocapnic cold air hyperventilation in 8 asthmatics." | 3.67 | Effect of alpha-adrenergic blockade on exercise-induced asthma and conditioned cold air. ( Bleecker, ER; Britt, EJ; Chahal, K; Mason, P; Permutt, S; Walden, SM, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (92.31) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liebhart, E | 1 |
| Suchnicka, R | 1 |
| Krasnowska, M | 1 |
| Barnes, PJ | 1 |
| Walden, SM | 1 |
| Bleecker, ER | 1 |
| Chahal, K | 1 |
| Britt, EJ | 1 |
| Mason, P | 1 |
| Permutt, S | 1 |
| Mue, S | 1 |
| Ohmi, T | 1 |
| Suzuki, S | 1 |
| Tamura, G | 1 |
| Hida, W | 1 |
| Sekizawa, K | 1 |
| Ishihara, T | 1 |
| Yamauchi, K | 1 |
| Takishima, T | 1 |
| Shiner, RJ | 1 |
| Molho, MI | 1 |
| Spector, S | 1 |
| Beil, M | 1 |
| Brecht, HM | 1 |
| Rasche, B | 1 |
| Drazen, JM | 1 |
| Brimacombe, J | 1 |
| Archdeacon, J | 1 |
| Newell, S | 1 |
| Martin, J | 1 |
| Gross, GN | 1 |
| Souhrada, JF | 1 |
| Farr, RS | 1 |
| Marcelle, R | 2 |
| Sly, RM | 1 |
| Heimlich, EM | 1 |
| Busser, RJ | 1 |
| Strick, L | 1 |
3 trials available for phentolamine and Bronchial Spasm
| Article | Year |
|---|---|
Comparison between an alpha-adrenergic antagonist and a beta 2-adrenergic agonist in bronchial asthma.
Topics: Adult; Albuterol; Asthma; Bronchial Spasm; Drug Evaluation; Drug Therapy, Combination; Female; Human | 1983 |
Tolerance to beta-adrenergics and results of rising dose studies of albuterol, isoproterenol and placebo.
Topics: Adult; Aerosols; Albuterol; Asthma; Bronchial Spasm; Clinical Trials as Topic; Dose-Response Relatio | 1981 |
The longterm treatment of an asthmatic patient using phentolamine.
Topics: Administration, Oral; Asthma; Atropine; Blood Pressure; Bronchial Spasm; Bronchodilator Agents; Chlo | 1974 |
10 other studies available for phentolamine and Bronchial Spasm
| Article | Year |
|---|---|
[Protective effect of adrenergic alpha blockaders on posthistamine bronchial spasm].
Topics: Adrenergic alpha-Antagonists; Adult; Albuterol; Asthma; Bronchial Provocation Tests; Bronchial Spasm | 1981 |
Adrenergic receptors of normal and asthmatic airways.
Topics: Adrenergic alpha-Agonists; Albuterol; Asthma; Bronchial Spasm; Catecholamines; Dose-Response Relatio | 1984 |
Effect of alpha-adrenergic blockade on exercise-induced asthma and conditioned cold air.
Topics: Adrenergic alpha-Antagonists; Adult; Air Conditioning; Airway Resistance; Antigens; Asthma; Asthma, | 1984 |
The effect of adrenergic and cholinergic drugs on methacholine- and histamine-induced bronchoconstriction in monkeys.
Topics: Animals; Atropine; Bronchial Spasm; Female; Isoproterenol; Macaca; Male; Phentolamine; Respiration | 1983 |
Plasma catecholamines in exercise induced bronchoconstriction.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Airway Resistance; Asthma; Bronchi | 1977 |
Adrenergic influences on histamine-mediated bronchoconstriction in the guinea pig.
Topics: Adrenal Glands; Adrenalectomy; Animals; Bronchial Spasm; Guinea Pigs; Histamine; Lung Compliance; Ma | 1978 |
Two cases of naloxone-induced pulmonary oedema--the possible use of phentolamine in management.
Topics: Adolescent; Aged; Bronchial Spasm; Furosemide; Humans; Hydrocortisone; Male; Midazolam; Naloxone; Ph | 1991 |
[Asthma therapy with phentolamine].
Topics: Adrenergic beta-Antagonists; Adult; Aerosols; Asthma; Bronchial Spasm; Bronchodilator Agents; Female | 1969 |
[Effect of DSCG on human bronchomotor activity in vitro].
Topics: Adrenergic alpha-Antagonists; Asthma; Bronchi; Bronchial Spasm; Chromones; Constriction; Cromolyn So | 1970 |
Exercise-induced bronchospasm: effect of adrenergic or cholinergic blockade.
Topics: Asthma; Atropine; Bronchial Spasm; Cardiovascular System; Child; Humans; Phentolamine; Physical Exer | 1967 |