Page last updated: 2024-11-06

phentolamine and Bradyarrhythmia

phentolamine has been researched along with Bradyarrhythmia in 25 studies

Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.

Research Excerpts

ExcerptRelevanceReference
"Vasodepressor reactions, characterized by paradoxic bradycardia, were induced in rats when the inferior vena cava was occluded during an infusion of isoproterenol."3.69Paradoxic bradycardia (vasodepressor reaction) induced by inferior vena cava occlusion: the role of alpha- and beta-adrenergic receptors and their interaction. ( Asta, JA; Cameron, DA; Waxman, MB, 1994)
"05) and the hypertension was significantly decreased by phentolamine and propranolol pretreatments (P < 0."3.69Cardiovascular reflex mechanisms by topical instillation of capsaicin and distilled water into the larynx in anesthetized dogs. ( Mutoh, T; Nishimura, R; Sasaki, N; Tsubone, H, 1997)
" Carbachol (1 microgram/kg) or physostigmine (50 micrograms/kg) induced a long-lasting increase in blood pressure and a decrease in heart rate in Long-Evans rats whereas no bradycardia was observed in Brattleboro rats, and the pressor response was significantly less than that in Long-Evans rats."3.67Role of vasopressin in cardiovascular response to central cholinergic stimulation in rats. ( Abe, K; Imai, Y; Minami, N; Munakata, M; Nobunaga, T; Sasaki, S; Sekino, H; Yoshinaga, K; Yumita, S, 1989)
"Syncope of patients with bradyarrhythmia is perceived as severe sign of low cardiac output caused by bradycardia and as a major criteria for pacemaker implantation (PMI)."1.30[Possible contribution of alpha-adrenergic abnormalities to cerebral ischemia in the patients with sinus bradycardia. Analysis by pharmacologic autonomic nervous test]. ( Atarashi, H; Hayakawa, H; Nomura, A; Saitoh, H, 1999)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199020 (80.00)18.7374
1990's4 (16.00)18.2507
2000's0 (0.00)29.6817
2010's1 (4.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Eme, J1
Rhen, T1
Crossley, DA1
SCHLEPPER, M1
WITZLER, E1
REINS, DA1
HOLMES, DD1
HINSHAW, LB1
Nymark, M1
Rasmussen, J1
Gaw, AJ1
Hills, DM1
Spraggs, CF1
Waxman, MB1
Asta, JA1
Cameron, DA1
Mutoh, T1
Tsubone, H1
Nishimura, R1
Sasaki, N1
Nomura, A1
Saitoh, H1
Atarashi, H1
Hayakawa, H1
Tadepalli, AS1
Mills, E1
Schanberg, SM1
James, TN1
Isobe, JH1
Urthaler, F1
Dhasmana, KM1
Banerjee, AK1
Saxena, PR1
Imai, Y1
Abe, K1
Sasaki, S1
Minami, N1
Munakata, M1
Yumita, S1
Nobunaga, T1
Sekino, H1
Yoshinaga, K1
Naidu, KA1
Radhakrishnamurty, R1
Samonina, GE1
Iashina, LP1
Pokrovskiĭ, VM1
Khakon, SM1
Kade, AKh1
Elliott, JM1
Kapoor, V1
Cain, M1
West, MJ1
Chalmers, JP1
Kobinger, W2
Walland, A2
Haeusler, G1
Gerold, M1
Thoenen, H1
Schröder, R1
Vander Ark, GD1
Norton, LW1
Pomerantz, M1
Korczyn, AD1
Bruderman, I1
Braun, K1
Ettinger, S1
Gould, L1
Carmichael, JA1
Tashjian, RJ1
Achari, NK1
Downman, CB1
Thuránszky, K1

Other Studies

25 other studies available for phentolamine and Bradyarrhythmia

ArticleYear
Adjustments in cholinergic, adrenergic and purinergic control of cardiovascular function in snapping turtle embryos (Chelydra serpentina) incubated in chronic hypoxia.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2014, Volume: 184, Issue:7

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Bradycardia; DNA, Comp

2014
[THE EFFECT OF ALTERED PRESSOR RECEPTOR STIMULATION IN THE CAROTID SINUS ON THE TONE OF PERIPHERAL BLOOD VESSELS IN MAN].
    Pflugers Archiv fur die gesamte Physiologie des Menschen und der Tiere, 1963, Volume: 277

    Topics: Bradycardia; Carotid Sinus; Central Nervous System; Electrocardiography; Humans; Male; Phentolamine;

1963
ACUTE AND CHRONIC EFFECTS OF THE INSECTICIDE ENDRIN ON RENAL FUNCTION AND RENAL HEMODYNAMICS.
    Canadian journal of physiology and pharmacology, 1964, Volume: 42

    Topics: Adrenalectomy; Animals; Blood Circulation; Bradycardia; Creatine; Creatinine; Dogs; Endrin; Glomerul

1964
Effect of certain drugs upon amitriptyline induced electrocardiographic changes.
    Acta pharmacologica et toxicologica, 1966, Volume: 24, Issue:2

    Topics: Acetylcholine; Amitriptyline; Animals; Atropine; Blood Pressure; Bradycardia; Bundle-Branch Block; E

1966
Characterization of the receptors and mechanisms involved in the cardiovascular actions of sCCK-8 in the pithed rat.
    British journal of pharmacology, 1995, Volume: 115, Issue:4

    Topics: Adrenalectomy; Adrenergic Agents; Animals; Benzodiazepinones; Blood Pressure; Bradycardia; Cholecyst

1995
Paradoxic bradycardia (vasodepressor reaction) induced by inferior vena cava occlusion: the role of alpha- and beta-adrenergic receptors and their interaction.
    Canadian journal of physiology and pharmacology, 1994, Volume: 72, Issue:11

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Re

1994
Cardiovascular reflex mechanisms by topical instillation of capsaicin and distilled water into the larynx in anesthetized dogs.
    The Journal of veterinary medical science, 1997, Volume: 59, Issue:9

    Topics: Administration, Topical; Anesthesia, General; Animals; Anti-Arrhythmia Agents; Antihypertensive Agen

1997
[Possible contribution of alpha-adrenergic abnormalities to cerebral ischemia in the patients with sinus bradycardia. Analysis by pharmacologic autonomic nervous test].
    Nihon Ika Daigaku zasshi, 1999, Volume: 66, Issue:2

    Topics: Adolescent; Adult; Aged; Arrhythmia, Sinus; Atropine; Autonomic Nervous System; Bradycardia; Brain I

1999
Depression and enhancement of baroreceptor pressor response in cats after intracerebroventricular injection of noradrenergic blocking agents: dependence on supracollicular areas of the brain.
    Circulation research, 1976, Volume: 39, Issue:5

    Topics: Animals; Arterial Occlusive Diseases; Bradycardia; Carotid Artery Diseases; Cats; Decerebrate State;

1976
Analysis of components in a cardiogenic hypertensive chemoreflex.
    Circulation, 1975, Volume: 52, Issue:2

    Topics: Animals; Atropine; Blood Pressure; Bradycardia; Cardiovascular System; Chemoreceptor Cells; Coronary

1975
Hypotension and bradycardia after intrathecal ketanserin and phentolamine in the rat.
    European journal of pharmacology, 1989, Sep-13, Volume: 168, Issue:2

    Topics: Animals; Blood Pressure; Bradycardia; Female; Heart Rate; Hypotension; Injections, Spinal; Ketanseri

1989
Role of vasopressin in cardiovascular response to central cholinergic stimulation in rats.
    Hypertension (Dallas, Tex. : 1979), 1989, Volume: 13, Issue:6 Pt 1

    Topics: Animals; Arginine Vasopressin; Atropine Derivatives; Autonomic Nervous System; Blood Pressure; Brady

1989
Metalaxyl-induced bradycardia in rats: mediated by alpha-adrenoreceptors.
    Journal of toxicology and environmental health, 1988, Volume: 23, Issue:4

    Topics: Alanine; Animals; Bradycardia; Female; Fungicides, Industrial; Heart Arrest; Heart Rate; Injections,

1988
[Participation of alpha and beta adrenoreceptors in facilitating and inhibiting the action of the sympathetic nervous system in parasympathetic bradycardia].
    Biulleten' eksperimental'noi biologii i meditsiny, 1988, Volume: 105, Issue:6

    Topics: Animals; Bradycardia; Cats; Electric Stimulation; Parasympathetic Nervous System; Phentolamine; Prop

1988
[Sympathetic efferent activity in various nerves and regional blood flow in controlled bradycardia].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1988, Volume: 74, Issue:5

    Topics: Animals; Blood Circulation; Bradycardia; Cats; Efferent Pathways; Electrophysiology; Femoral Nerve;

1988
The mechanism of hypertension and bradycardia following lesions of the caudal ventrolateral medulla in the rabbit: the role of sympathetic nerves, circulating adrenaline, vasopressin and renin.
    Clinical and experimental hypertension. Part A, Theory and practice, 1985, Volume: 7, Issue:8

    Topics: Adrenalectomy; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine Vasopressin; Bradycardia;

1985
Involvement of adrenergic receptors in central vagus activity.
    European journal of pharmacology, 1971, Volume: 16, Issue:1

    Topics: Angiotensin II; Animals; Blood Pressure; Bradycardia; Clonidine; Dogs; Heart Rate; Phentolamine; Rec

1971
Cardiovascular effects of 6-hydroxydopamine injected into a lateral brain ventricle of the rat.
    Naunyn-Schmiedeberg's archives of pharmacology, 1972, Volume: 274, Issue:3

    Topics: Animals; Blood Pressure; Bradycardia; Brain; Cerebral Ventricles; Desoxycorticosterone; Dopamine; Fe

1972
Facilitation of vagal reflex bradycardia by an action of clonidine on central -receptors.
    European journal of pharmacology, 1972, Volume: 19, Issue:2

    Topics: Acetylcholine; Adrenergic beta-Antagonists; Animals; Blood Pressure; Bradycardia; Cerebellum; Chlorp

1972
[Drug therapy of hemodynamic complications in acute myocardial infarct].
    Der Internist, 1972, Volume: 13, Issue:9

    Topics: Aged; Analgesia; Anti-Arrhythmia Agents; Blood Volume; Bradycardia; Cardiovascular Diseases; Diazepa

1972
The effects of brain stem compression on the heart.
    Surgical neurology, 1974, Volume: 2, Issue:4

    Topics: Animals; Arrhythmias, Cardiac; Atropine; Blood Pressure; Bradycardia; Brain Injuries; Brain Stem; Ca

1974
Cardiovascular effects of lobeline.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 182, Issue:2

    Topics: Anesthesia, Inhalation; Anesthesia, Spinal; Animals; Atropine; Blood Pressure; Bradycardia; Cardiova

1969
Phentolamine: use in digitalis-induced arrhythmias. Canine experiments.
    American heart journal, 1969, Volume: 77, Issue:5

    Topics: Animals; Arrhythmias, Cardiac; Bradycardia; Dogs; Electrocardiography; Heart Block; Ouabain; Phentol

1969
Autonomic responses evoked by stimulation of fastigial nuclei in the anaesthetized cat.
    The Journal of physiology, 1969, Volume: 204, Issue:2

    Topics: Animals; Autonomic Nervous System; Blood Pressure; Bradycardia; Carotid Sinus; Cats; Cerebellum; Ele

1969
The role of the central nervous system on the action of epinephrine and adrenolytic drugs.
    Archives internationales de pharmacodynamie et de therapie, 1966, Volume: 159, Issue:1

    Topics: Animals; Blood Pressure; Bradycardia; Cats; Central Nervous System; Chlorpromazine; Decerebrate Stat

1966