phentolamine has been researched along with Bleeding in 40 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Alpha receptor and angiotensin II blockade were used to study renal cortical vasoconstrictor mechanisms during hemorrhage to 70 mmHg in chloralose-urethane anesthetized dogs." | 7.66 | Angiotensin II and alpha-adrenergic control of the intrarenal circulation in hemorrhage. ( Hock, CE; Levin, JI; Neiberger, RE; Passmore, JC, 1982) |
| "Opiate receptor blockade with naloxone reverses the hypotension associated with severe hemorrhage in a variety of animal models." | 7.66 | Involvement of both adrenergic and cholinergic receptors in the cardiovascular effects of naloxone during hemorrhagic hypotension in the conscious rabbit. ( Schadt, JC; York, DH, 1982) |
| "A case of ruptured pheochromocytoma is presented, the pathophysiology discussed, and the literature reviewed." | 5.26 | Hemorrhagic necrosis of pheochromocytoma associated with phentolamine administration. ( Cleveland, HC; Faraci, RP; Foster, JF; Scott, HW; Van Way, CW, 1976) |
| " To test the role of the adrenergic system, alpha- and beta-adrenergic receptor antagonists, phentolamine and propranolol, were tested for the ability to block HDIR produced by hemorrhage." | 3.73 | Hemorrhage results in hepatic insulin-sensitizing substance-dependent insulin resistance mediated by somatostatin in rats. ( Lautt, WW; Seredycz, LI, 2006) |
| "The effects of phentolamine, KBIV24 and captopril on the mean arterial blood pressure of normal and treated (dehydration, hemorrhage) frogs were determined." | 3.67 | Blood pressure homeostasis in Rana catesbeiana under normal and hypovolemic conditions. ( Chiu, KW; Pang, PK; Sham, JS; Wong, VC, 1984) |
| "The effect of arginine vasopressin (AVP) pressor blockade on the response to graded hemorrhage was investigated on conscious, unstressed, freely moving rats." | 3.67 | Cardiovascular and hormonal response to hemorrhage in conscious rats. ( Brinck-Johnsen, T; Fejes-Tóth, G; Náray-Fejes-Tóth, A, 1988) |
| "Alpha receptor and angiotensin II blockade were used to study renal cortical vasoconstrictor mechanisms during hemorrhage to 70 mmHg in chloralose-urethane anesthetized dogs." | 3.66 | Angiotensin II and alpha-adrenergic control of the intrarenal circulation in hemorrhage. ( Hock, CE; Levin, JI; Neiberger, RE; Passmore, JC, 1982) |
| "Opiate receptor blockade with naloxone reverses the hypotension associated with severe hemorrhage in a variety of animal models." | 3.66 | Involvement of both adrenergic and cholinergic receptors in the cardiovascular effects of naloxone during hemorrhagic hypotension in the conscious rabbit. ( Schadt, JC; York, DH, 1982) |
| " Because BCO is followed by increase of left ventricle end-diastolic pressure (LVEDP) and of blood pressure (BP), to avoid the influence of these variables on dp/dt, we have reduced preload and afterload by means of hemorrhage (group A) and alpha-adrenergic blocker administration--phentolamine (group B)." | 3.66 | Inversion of cardiac inotropism response to carotid arteries occlusion in dogs treated with propranolol. ( Bregagnollo, EA; Cicogna, AC; Spadaro, J; Tucci, PJ, 1980) |
| " Pretreatment with phenoxybenzamine, phentolamine, propranolol, or atropine did not alter the redistribution of cortical flow during hemorrhage." | 3.65 | Mechanism of the redistribution of renal cortical blood flow during hemorrhagic hypotension in the dog. ( Boonjarern, S; Ferris, TF; Mauk, RC; Stein, JH, 1973) |
| "Hemorrhage was induced in fasted anesthetized rats, and the reduction of blood pressure to 40 mm Hg for a duration of 30 minutes was accomplished by withdrawal or infusion of shed blood." | 1.31 | Regulation of liver and kidney glucose-6-phosphatase gene expression in hemorrhage and resuscitation. ( El-Maghrabi, MR; Henry, MC; Maitra, SR; Wang, S, 2000) |
| "In contrast, treatment before hemorrhage with the beta-adrenergic receptor antagonist propranolol was associated with increases in mRNA levels for IL-1beta, TNF-alpha, and TGF-beta1, which were greater than those present in untreated hemorrhaged mice, and did not prevent hemorrhage-associated increases in lung IL-1beta protein." | 1.30 | Hemorrhage increases cytokine expression in lung mononuclear cells in mice: involvement of catecholamines in nuclear factor-kappaB regulation and cytokine expression. ( Abraham, E; Dinarello, CA; Fantuzzi, G; Kaneko, D; Le Tulzo, Y; Moine, P; Shenkar, R, 1997) |
| "Phentolamine pretreatment, which in itself caused a 55% decrease in dorsal aortic pressure, did not prevent the recovery of blood pressure after hemorrhage." | 1.27 | Vascular recovery following hemorrhage in the dogfish shark Squalus acanthias. ( Carroll, RG; Keller, NE; Opdyke, DF, 1984) |
| "Octopamine was hypertensive in doses of 100 micrograms/min and more and this change was associated with a significant decrement in GFR and renal perfusion." | 1.27 | Effects of octopamine on renal function in anaesthetized dogs. ( Levy, M, 1988) |
| "These arrhythmias have responded to sympathetic blocking agents, which may also have a protective effect on subendocardial tissue in this setting." | 1.27 | Subarachnoid hemorrhage and the heart. ( Marion, DW; Segal, R; Thompson, ME, 1986) |
| "In phentolamine-treated animals, bleeding produced a drop in AP and CO similar to that observed in the nontreated animals; however, the decrease in CBF was less marked." | 1.26 | Cerebral blood flow during hemorrhagic hypotension in the unanesthetized goat. ( Alborch, E; Dieguez, G; Gómez, B; Lluch, S; Vallejo, AR, 1977) |
| "A case of ruptured pheochromocytoma is presented, the pathophysiology discussed, and the literature reviewed." | 1.26 | Hemorrhagic necrosis of pheochromocytoma associated with phentolamine administration. ( Cleveland, HC; Faraci, RP; Foster, JF; Scott, HW; Van Way, CW, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (70.00) | 18.7374 |
| 1990's | 5 (12.50) | 18.2507 |
| 2000's | 7 (17.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arcaroli, J | 2 |
| Yang, KY | 1 |
| Yum, HK | 1 |
| Kupfner, J | 1 |
| Pitts, TM | 1 |
| Park, JS | 1 |
| Strassheim, D | 1 |
| Abraham, E | 3 |
| Lai, HY | 1 |
| Yang, CC | 1 |
| Huang, FY | 1 |
| Lee, Y | 1 |
| Kuo, YL | 1 |
| Kuo, TB | 1 |
| MCGIFF, JC | 1 |
| Frisbee, JC | 1 |
| Seredycz, LI | 1 |
| Lautt, WW | 1 |
| Sham, JS | 1 |
| Wong, VC | 1 |
| Chiu, KW | 1 |
| Pang, PK | 1 |
| Kopelman, RI | 1 |
| Dzau, VJ | 1 |
| Shimabukuro, S | 1 |
| Barger, AC | 1 |
| Hock, CE | 1 |
| Passmore, JC | 1 |
| Levin, JI | 1 |
| Neiberger, RE | 1 |
| Schadt, JC | 2 |
| York, DH | 1 |
| Carroll, RG | 1 |
| Opdyke, DF | 1 |
| Keller, NE | 1 |
| Ploucha, JM | 1 |
| Bursian, SJ | 1 |
| Ringer, RK | 1 |
| Scott, JB | 1 |
| Cicogna, AC | 1 |
| Spadaro, J | 1 |
| Bregagnollo, EA | 1 |
| Tucci, PJ | 1 |
| Theuer, CJ | 1 |
| Wilson, MA | 1 |
| Spain, DA | 1 |
| Edwards, MJ | 1 |
| Garrison, RN | 1 |
| Michalicek, J | 1 |
| Campbell, G | 1 |
| Le Tulzo, Y | 1 |
| Shenkar, R | 2 |
| Kaneko, D | 1 |
| Moine, P | 1 |
| Fantuzzi, G | 1 |
| Dinarello, CA | 1 |
| Tanaka, J | 1 |
| Hayashi, Y | 1 |
| Shimamune, S | 1 |
| Nomura, M | 1 |
| Maitra, SR | 1 |
| Wang, S | 1 |
| El-Maghrabi, MR | 1 |
| Henry, MC | 1 |
| Baniel, J | 1 |
| Israilov, S | 1 |
| Engelstein, D | 1 |
| Shmueli, J | 1 |
| Segenreich, E | 1 |
| Livne, PM | 1 |
| Lindsey, CA | 1 |
| Faloona, GR | 1 |
| Unger, RH | 1 |
| Drózdz, M | 1 |
| Kucharz, E | 1 |
| Wieczorek, M | 1 |
| Teplov, SI | 1 |
| Balueva, TV | 1 |
| Lluch, S | 2 |
| Vallejo, AR | 2 |
| Dieguez, G | 2 |
| Gómez, B | 2 |
| Alborch, E | 1 |
| Van Way, CW | 1 |
| Faraci, RP | 1 |
| Cleveland, HC | 1 |
| Foster, JF | 1 |
| Scott, HW | 1 |
| Bove, EL | 1 |
| Argenta, LC | 1 |
| Cimmino, VM | 1 |
| Brown, JW | 1 |
| Nishiyama, RH | 1 |
| Kirsh, MM | 1 |
| Hasser, EM | 1 |
| Ogilvy, CS | 1 |
| Tremml, PG | 1 |
| DuBois, AB | 1 |
| Levy, M | 1 |
| Fejes-Tóth, G | 1 |
| Brinck-Johnsen, T | 1 |
| Náray-Fejes-Tóth, A | 1 |
| Marion, DW | 1 |
| Segal, R | 1 |
| Thompson, ME | 1 |
| Murata, Y | 1 |
| Miyake, Y | 1 |
| Yamamoto, T | 1 |
| Higuchi, M | 1 |
| Hesser, J | 1 |
| Ibara, S | 1 |
| Bessho, T | 1 |
| Tyner, JG | 1 |
| Vatner, SF | 1 |
| DuCharme, DW | 1 |
| Beck, L | 1 |
| Ross, EJ | 1 |
| Prichard, BN | 1 |
| Kaufman, L | 1 |
| Robertson, AI | 1 |
| Harries, BJ | 1 |
| Huang, WC | 1 |
| Lee, RS | 1 |
| Young, TK | 1 |
| Rayssiguier, Y | 1 |
| Larvor, P | 1 |
| Stein, JH | 1 |
| Boonjarern, S | 1 |
| Mauk, RC | 1 |
| Ferris, TF | 1 |
| Beard, J | 1 |
| Yarom, R | 1 |
| Braun, K | 1 |
1 review available for phentolamine and Bleeding
| Article | Year |
|---|---|
Venous pressure and other thoughts.
Topics: Anesthesia; Blood Pressure; Blood Volume Determination; Cardiac Output; Catecholamines; Chlorpromazi | 1969 |
1 trial available for phentolamine and Bleeding
| Article | Year |
|---|---|
Three-year outcome of a progressive treatment program for erectile dysfunction with intracavernous injections of vasoactive drugs.
Topics: Adult; Aged; Aged, 80 and over; Alprostadil; Drug Therapy, Combination; Erectile Dysfunction; Follow | 2000 |
38 other studies available for phentolamine and Bleeding
| Article | Year |
|---|---|
Effects of catecholamines on kinase activation in lung neutrophils after hemorrhage or endotoxemia.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-A | 2002 |
Respiratory-related arterial pressure variability as an indicator of graded blood loss: involvement of the autonomic nervous system.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia; Animals; Arteries; Atropine; | 2003 |
THE RENAL VASCULAR RESPONSE TO HEMORRHAGE.
Topics: Adrenalectomy; Animals; Autonomic Nervous System; Blood Circulation; Denervation; Dogs; Guanethidine | 1964 |
Impaired hemorrhage tolerance in the obese Zucker rat model of metabolic syndrome.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Blood Volume; Disease Models, Animal; Dose-Re | 2006 |
Hemorrhage results in hepatic insulin-sensitizing substance-dependent insulin resistance mediated by somatostatin in rats.
Topics: Adrenergic Agents; Analysis of Variance; Animals; Blood Glucose; Glucose Clamp Technique; Hemorrhage | 2006 |
Blood pressure homeostasis in Rana catesbeiana under normal and hypovolemic conditions.
Topics: Animals; Blood Pressure; Captopril; Catecholamines; Dehydration; Hemorrhage; Homeostasis; Phentolami | 1984 |
Compensatory response to hemorrhage in conscious dogs on normal and low salt intake.
Topics: Animals; Blood Pressure; Diet, Sodium-Restricted; Dogs; Epinephrine; Heart Rate; Hematocrit; Hemorrh | 1983 |
Angiotensin II and alpha-adrenergic control of the intrarenal circulation in hemorrhage.
Topics: Angiotensin II; Animals; Dogs; Hemorrhage; Kidney Cortex; Phentolamine; Receptors, Adrenergic; Recep | 1982 |
Involvement of both adrenergic and cholinergic receptors in the cardiovascular effects of naloxone during hemorrhagic hypotension in the conscious rabbit.
Topics: Adrenergic Fibers; Animals; Atropine; Blood Pressure; Efferent Pathways; Heart Rate; Hemodynamics; H | 1982 |
Vascular recovery following hemorrhage in the dogfish shark Squalus acanthias.
Topics: Animals; Aorta; Blood Pressure; Blood Vessels; Dogfish; Epinephrine; Hematocrit; Hemorrhage; Norepin | 1984 |
Effects of severe hemorrhagic hypotension on the vasculature of the chicken.
Topics: Animals; Chickens; Denervation; Dopamine; Female; Hemorrhage; Hypotension; Male; Norepinephrine; Phe | 1982 |
Inversion of cardiac inotropism response to carotid arteries occlusion in dogs treated with propranolol.
Topics: Animals; Blood Pressure; Carotid Arteries; Depression, Chemical; Dogs; Heart Rate; Hemodynamics; Hem | 1980 |
Alpha-adrenergic receptor antagonism prevents intestinal vasoconstriction but not hypoperfusion following resuscitated hemorrhage.
Topics: Adrenergic alpha-Antagonists; Animals; Arterioles; Blood Pressure; Cardiac Output; Dose-Response Rel | 1995 |
Autonomic regulation of heart rate and blood pressure in hemorrhaged toads.
Topics: Animals; Atropine; Autonomic Nerve Block; Autonomic Nervous System; Blood Pressure; Bretylium Compou | 1993 |
Hemorrhage increases cytokine expression in lung mononuclear cells in mice: involvement of catecholamines in nuclear factor-kappaB regulation and cytokine expression.
Topics: Animals; Catecholamines; Cyclic AMP Response Element-Binding Protein; Cytokines; Hemorrhage; Lung; M | 1997 |
Ascending pathways from the nucleus of the solitary tract to the subfornical organ in the rat.
Topics: Afferent Pathways; Animals; Electric Stimulation; Electrophysiology; Hemorrhage; Iontophoresis; Male | 1997 |
Regulation of liver and kidney glucose-6-phosphatase gene expression in hemorrhage and resuscitation.
Topics: Analysis of Variance; Animals; Blood Glucose; Blotting, Northern; Disease Models, Animal; Gene Expre | 2000 |
Activation of extracellular signal-regulated kinases, NF-kappa B, and cyclic adenosine 5'-monophosphate response element-binding protein in lung neutrophils occurs by differing mechanisms after hemorrhage or endotoxemia.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animal Feed; Animals; Cyclic AMP Response | 2001 |
PLasma glucagon levels during rapid exsanguination with and without adrenergic blockade.
Topics: Adrenergic beta-Antagonists; Animals; Blood Glucose; Dogs; Glucagon; Hemorrhage; Hypotension; Insuli | 1975 |
Morphological changes observed after stimulation or inhibition of adrenic system in rats chronically treated with hydrazinophtalazines.
Topics: Animals; Catecholamines; Epinephrine; Heart; Heart Diseases; Hemorrhage; Hydralazine; Inflammation; | 1979 |
[Changes in coronary circulation following reflex excitation of the sympathetic nervous system].
Topics: Animals; Arterial Occlusive Diseases; Atropine; Blood Pressure; Carotid Artery Diseases; Carotid Sin | 1978 |
Adrenergic involvement in cerebral blood flow: changes in controlled hypotension.
Topics: Animals; Cerebrovascular Circulation; Female; Goats; Hemorrhage; Hypotension; Hypotension, Controlle | 1978 |
Cerebral blood flow during hemorrhagic hypotension in the unanesthetized goat.
Topics: Animals; Blood Pressure; Cardiac Output; Cerebrovascular Circulation; Female; Goats; Hemorrhage; Hyp | 1977 |
Hemorrhagic necrosis of pheochromocytoma associated with phentolamine administration.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aged; Female; Hemorrhage; Humans; Hypertension; Necr | 1976 |
The morphologic effects of simultaneous infusion of levarterenol and phentolamine on the canine myocardium.
Topics: Animals; Blood Pressure; Cardiac Output; Dogs; Drug Interactions; Heart; Hemorrhage; Necrosis; Norep | 1975 |
Sympathoinhibition and its reversal by naloxone during hemorrhage.
Topics: Analysis of Variance; Animals; Blood Pressure; Heart Rate; Hemodynamics; Hemorrhage; Kidney; Male; N | 1992 |
Pressor and hemodilution responses compensate for acute hemorrhage in bluefish.
Topics: Animals; Atropine; Blood Pressure; Blood Volume; Epinephrine; Fishes; Heart Rate; Hemodilution; Hemo | 1988 |
Effects of octopamine on renal function in anaesthetized dogs.
Topics: Animals; Dogs; Female; Hemorrhage; Infusions, Intravenous; Jaundice; Kidney; Lithium; Liver Cirrhosi | 1988 |
Cardiovascular and hormonal response to hemorrhage in conscious rats.
Topics: Animals; Arginine Vasopressin; Blood Pressure; Captopril; Cardiac Output; Cardiovascular System; Cat | 1988 |
Subarachnoid hemorrhage and the heart.
Topics: Adult; Arrhythmias, Cardiac; Bibliographies as Topic; Catecholamines; Coronary Disease; Electrocardi | 1986 |
Experimentally produced sinusoidal fetal heart rate pattern in the chronically instrumented fetal lamb.
Topics: Animals; Arginine Vasopressin; Blood Pressure; Cardiac Catheterization; Electrodes; Epinephrine; Fem | 1985 |
Effects of hemorrhage on regional blood flow distribution in dogs and primates.
Topics: Animals; Atropine; Blood Circulation; Blood Flow Velocity; Blood Pressure; Cardiac Output; Coronary | 1974 |
The relative effect of the renal pressor and sympathetic nervous systems on vascular capacity during hypotension.
Topics: Anesthesia, Spinal; Angiotensin II; Animals; Blood Pressure; Dogs; Female; Hematocrit; Hemorrhage; H | 1971 |
Preoperative and operative management of patients with phaeochromocytoma.
Topics: Adolescent; Adult; Anesthetics; Arrhythmias, Cardiac; Blood Pressure; Blood Volume; Child; Ethanolam | 1967 |
Depletion of neurohypophysial vasopressin content in rats following hemorrhage.
Topics: Animals; Blood Pressure; Female; Hemorrhage; Hypotension; Male; Phenoxybenzamine; Phentolamine; Pitu | 1974 |
[Hypermagnesemia and medullo-adrenal secretion].
Topics: Adaptation, Physiological; Adrenal Medulla; Animals; Atropine; Blood Glucose; Carbachol; Cold Temper | 1972 |
Mechanism of the redistribution of renal cortical blood flow during hemorrhagic hypotension in the dog.
Topics: Animals; Aorta, Abdominal; Atropine; Blood Flow Velocity; Blood Pressure; Blood Transfusion, Autolog | 1973 |
Cardiovascular effects of scorpion venom, morphological changes in the myocardium.
Topics: Animals; Antivenins; Coronary Vessels; Dibenzylchlorethamine; Dogs; Heart; Heart Diseases; Hemorrhag | 1970 |