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phentolamine and Asthma, Bronchial

phentolamine has been researched along with Asthma, Bronchial in 39 studies

Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.

Research Excerpts

ExcerptRelevanceReference
"In this work, effect of phentolamine as antagonist of alpha-1 adrenergic receptor in patients with bronchial asthma and with obstructive chronic bronchitis was studied."7.77Phentolamine action in permeability of airways at patients with bronchial asthma. ( Ahmetaj, H; Ahmetaj, S; Haliti, N; Ibrahimi, I; Islami, H; Krasniqi, S; Kurtishi, I, 2011)
"Twenty patients with extrinsic type bronchial asthma are shown to have a significant fall in vital capacity (V."6.63Effect of alpha-receptor blocking drugs and disodium cromoglyate on histamine hypersensitivity in bronchial asthma. ( Govindaraj, M; Kerr, JW; Patel, KR, 1970)
"Fifteen patients suffering from asthma received inhalations of phentolamine, albuterol (salbutamol), a combination of phentolamine and albuterol, and placebo, in a single-blind fashion; the changes in the pulmonary function tests were recorded over a three-hour period."5.05Comparison between an alpha-adrenergic antagonist and a beta 2-adrenergic agonist in bronchial asthma. ( Molho, MI; Shiner, RJ, 1983)
"In this work, effect of phentolamine as antagonist of alpha-1 adrenergic receptor in patients with bronchial asthma and with obstructive chronic bronchitis was studied."3.77Phentolamine action in permeability of airways at patients with bronchial asthma. ( Ahmetaj, H; Ahmetaj, S; Haliti, N; Ibrahimi, I; Islami, H; Krasniqi, S; Kurtishi, I, 2011)
" To evaluate the role of alpha-adrenergic activity in the development of bronchoconstriction during airway cooling, we examined the effects of alpha-adrenergic blockade with phentolamine on bronchospasm induced by exercise and isocapnic cold air hyperventilation in 8 asthmatics."3.67Effect of alpha-adrenergic blockade on exercise-induced asthma and conditioned cold air. ( Bleecker, ER; Britt, EJ; Chahal, K; Mason, P; Permutt, S; Walden, SM, 1984)
"In asthmatics, alpha-adrenergic blockage with oral phentolamine partially or completely blocked bronchospasm after maximal exercise challenge."3.66The effect of alpha adrenergic blockade on non-specific airways reactivity and exercise induced asthma. ( Bleecker, ER; Chahal, KS; Mason, P; Permutt, S, 1983)
"Twenty patients with extrinsic type bronchial asthma are shown to have a significant fall in vital capacity (V."2.63Effect of alpha-receptor blocking drugs and disodium cromoglyate on histamine hypersensitivity in bronchial asthma. ( Govindaraj, M; Kerr, JW; Patel, KR, 1970)
"Phentolamine has been advocated for several years as a beneficial agent for the treatment of shock."1.26Phentolamine. ( Gould, L; Reddy, CV, 1976)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199037 (94.87)18.7374
1990's1 (2.56)18.2507
2000's0 (0.00)29.6817
2010's1 (2.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Islami, H1
Krasniqi, S1
Ahmetaj, H1
Haliti, N1
Kurtishi, I1
Ahmetaj, S1
Ibrahimi, I1
WISNIEWSKA, JM1
Liebhart, E1
Suchnicka, R2
Krasnowska, M3
Campbell, SC1
Smith, SR1
Barnes, PJ1
Walden, SM1
Bleecker, ER2
Chahal, K1
Britt, EJ1
Mason, P2
Permutt, S2
Reinhardt, D1
Nagel, M1
Stemmann, EA1
Wegner, F1
Chahal, KS1
Shiner, RJ1
Molho, MI1
Spector, S1
Jankowska, R1
Van Mieghem, W1
Stevens, E1
Billiet, L1
Marcelle, R3
Lee, TP1
Busse, WW1
Reed, CE1
Beil, M1
Brecht, HM1
Rasche, B1
Spector, SL1
Patel, KR4
Kerr, JW3
Henderson, WR1
Shelhamer, JH1
Reingold, DB1
Smith, LJ1
Evans, R1
Kaliner, M1
Chachaj, W2
Kraus-Filarska, M1
Löllgen, H1
von Nieding, G1
Löllgen-Horres, I1
Gould, L1
Reddy, CV1
Geumei, A1
Miller, JR1
Miller, WF1
Logsdon, PJ3
Carnright, DV2
Middleton, E3
Coffey, RG3
Alston, WC1
Van Cauwenberge, H1
Gross, GN1
Souhrada, JF1
Farr, RS1
Pegelow, KO1
Wrzyszcz, M1
Harwell, WB1
Patterson, JT1
Lieberman, P1
Beachey, E1
Govindaraj, M1
Vitale, P1
Scialdone, A1
Sly, RM1
Heimlich, EM1
Busser, RJ1
Strick, L1

Reviews

3 reviews available for phentolamine and Asthma, Bronchial

ArticleYear
Alpha-adrenergic blocking agents in the treatment of asthma.
    Journal of clinical and hospital pharmacy, 1983, Volume: 8, Issue:2

    Topics: Adrenergic alpha-Antagonists; Asthma; Humans; Indoramin; Moxisylyte; Phentolamine; Receptors, Adrene

1983
The role of adrenoceptors in bronchial asthma.
    Journal of the Royal College of Physicians of London, 1979, Volume: 13, Issue:3

    Topics: Adenylyl Cyclases; Animals; Asthma; Humans; Isoproterenol; Lung; Moxisylyte; Phentolamine; Phenyleph

1979
Leukocyte adenyl cyclase and ATPase in asthma: effect of corticosteroid therapy.
    Chest, 1973, Volume: 63

    Topics: Adenosine Triphosphate; Adenylyl Cyclases; Adrenergic beta-Agonists; Asthma; Cyclic AMP; Humans; Hyd

1973

Trials

7 trials available for phentolamine and Asthma, Bronchial

ArticleYear
Effects of alpha-adrenergic blockade with phentolamine on airway function in asthma.
    Annals of allergy, 1982, Volume: 49, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adult; Airway Resistance; Asthma; Forced Expiratory Volume; Humans; Ma

1982
Comparison between an alpha-adrenergic antagonist and a beta 2-adrenergic agonist in bronchial asthma.
    Chest, 1983, Volume: 83, Issue:4

    Topics: Adult; Albuterol; Asthma; Bronchial Spasm; Drug Evaluation; Drug Therapy, Combination; Female; Human

1983
Tolerance to beta-adrenergics and results of rising dose studies of albuterol, isoproterenol and placebo.
    Annals of allergy, 1981, Volume: 47, Issue:5 Pt 2

    Topics: Adult; Aerosols; Albuterol; Asthma; Bronchial Spasm; Clinical Trials as Topic; Dose-Response Relatio

1981
Letter: Alpha-receptor-blocking drugs in bronchial asthma.
    Lancet (London, England), 1975, Feb-08, Volume: 1, Issue:7902

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Airway Obstruction; Airway Resistance; Albut

1975
The longterm treatment of an asthmatic patient using phentolamine.
    Chest, 1974, Volume: 66, Issue:4

    Topics: Administration, Oral; Asthma; Atropine; Blood Pressure; Bronchial Spasm; Bronchodilator Agents; Chlo

1974
Effect of alpha-receptor blocking drugs and disodium cromoglyate on histamine hypersensitivity in bronchial asthma.
    British medical journal, 1970, Apr-18, Volume: 2, Issue:5702

    Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Asthma; Bronchi; Calcium; Cell Membrane; Chromones;

1970
[Effects of phentolamine on the ventilatory function of asthmatic subjects].
    La Clinica terapeutica, 1972, Dec-31, Volume: 63, Issue:6

    Topics: Aerosols; Asthma; Bronchodilator Agents; Clinical Trials as Topic; Humans; Phentolamine; Respiration

1972

Other Studies

29 other studies available for phentolamine and Asthma, Bronchial

ArticleYear
Phentolamine action in permeability of airways at patients with bronchial asthma.
    Medicinski arhiv, 2011, Volume: 65, Issue:1

    Topics: Adrenergic alpha-1 Receptor Antagonists; Airway Resistance; Asthma; Bronchi; Humans; Permeability; P

2011
PROPHYLACTIC ACTION OF REGITINE IN EXPERIMENTAL HISTAMINIC AND ALLERGIC BRONCHIAL ASTHMA.
    Archives internationales de pharmacodynamie et de therapie, 1964, May-01, Volume: 149

    Topics: Animals; Asthma; Guinea Pigs; Histamine; Pharmacology; Phentolamine; Research; Respiratory Hypersens

1964
[Protective effect of adrenergic alpha blockaders on posthistamine bronchial spasm].
    Pneumonologia polska, 1981, Volume: 49, Issue:11

    Topics: Adrenergic alpha-Antagonists; Adult; Albuterol; Asthma; Bronchial Provocation Tests; Bronchial Spasm

1981
Adrenergic receptors of normal and asthmatic airways.
    European journal of respiratory diseases. Supplement, 1984, Volume: 135

    Topics: Adrenergic alpha-Agonists; Albuterol; Asthma; Bronchial Spasm; Catecholamines; Dose-Response Relatio

1984
Effect of alpha-adrenergic blockade on exercise-induced asthma and conditioned cold air.
    The American review of respiratory disease, 1984, Volume: 130, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adult; Air Conditioning; Airway Resistance; Antigens; Asthma; Asthma,

1984
Catecholamines and cyclic AMP in allergic and exercise induced asthma of childhood.
    European journal of pediatrics, 1980, Volume: 134, Issue:1

    Topics: Adolescent; Airway Resistance; Asthma; Catecholamines; Child; Cromolyn Sodium; Cyclic AMP; Epinephri

1980
The effect of alpha adrenergic blockade on non-specific airways reactivity and exercise induced asthma.
    European journal of respiratory diseases. Supplement, 1983, Volume: 128 (Pt 1)

    Topics: Airway Resistance; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Histamine; Humans;

1983
[Electrocardiographic changes in asthma as affected by various drugs combined with phentolamine (Regitine)].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1981, Jun-08, Volume: 36, Issue:23

    Topics: Adult; Albuterol; Aminophylline; Asthma; Drug Therapy, Combination; Electrocardiography; Female; Hea

1981
Phentolamine therapy in severe chronic asthmatiform bronchitis.
    Respiration; international review of thoracic diseases, 1981, Volume: 42, Issue:3

    Topics: Adult; Arteries; Asthma; Blood Pressure; Chronic Disease; Female; Humans; Male; Middle Aged; Oxygen;

1981
Alpha-adrenergic bronchoconstriction in man.
    Archives of physiology and biochemistry, 1996, Volume: 104, Issue:7

    Topics: Administration, Inhalation; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta

1996
Effect of beta adrenergic agonist, prostaglandins, and cortisol on lymphocyte levels of cyclic adenosine monophosphate and glycogen: abnormal lymphocytic metabolism in asthma.
    The Journal of allergy and clinical immunology, 1977, Volume: 59, Issue:6

    Topics: Adrenergic beta-Agonists; Asthma; Cells, Cultured; Cyclic AMP; Drug Therapy, Combination; Epinephrin

1977
Plasma catecholamines in exercise induced bronchoconstriction.
    Klinische Wochenschrift, 1977, Jun-15, Volume: 55, Issue:12

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Airway Resistance; Asthma; Bronchi

1977
Alpha-adrenergic antagonists in asthmatic patients: a note of caution.
    The New England journal of medicine, 1979, Aug-16, Volume: 301, Issue:7

    Topics: Adrenergic alpha-Antagonists; Asthma; Bronchi; Humans; Phentolamine

1979
Alpha-adrenergic hyper-responsiveness in asthma.
    The New England journal of medicine, 1979, Mar-22, Volume: 300, Issue:12

    Topics: Adolescent; Adult; Asthma; Female; Humans; Male; Middle Aged; Phentolamine; Phenylephrine; Propranol

1979
[Effect of adrenaline or regitine on serum cortisol level in patients with asthma and in healthy subjects].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1978, Jan-16, Volume: 33, Issue:3

    Topics: Adult; Asthma; Epinephrine; Female; Humans; Hydrocortisone; Male; Middle Aged; Phentolamine

1978
Effect of an alpha-adrenergic-blocking drug on bronchodilation and protection in provocation tests in patients with chronic obstructive airways disease, bronchial asthma, and in non-responders.
    Respiration; international review of thoracic diseases, 1977, Volume: 34, Issue:6

    Topics: Acetylcholine; Adolescent; Adult; Aged; Asthma; Bronchi; Drug Resistance; Drug Therapy, Combination;

1977
Phentolamine.
    American heart journal, 1976, Volume: 92, Issue:3

    Topics: Angina Pectoris; Animals; Aortic Stenosis, Subvalvular; Arrhythmias, Cardiac; Asthma; Dogs; Heart Co

1976
Effects of phentolamine inhalation on patients with bronchial asthma.
    British journal of clinical pharmacology, 1975, Volume: 2, Issue:6

    Topics: Adult; Aerosols; Asthma; Drug Synergism; Drug Therapy, Combination; Female; Forced Expiratory Volume

1975
Alpha-blockade in treatment of asthma.
    Lancet (London, England), 1972, Jul-29, Volume: 2, Issue:7770

    Topics: Adenylyl Cyclases; Adrenergic alpha-Antagonists; Asthma; Drug Synergism; Humans; Isoproterenol; Leuk

1972
Response of leucocyte adenyl cyclase to isoprenaline and effect of alpha-blocking drugs in extrinsic bronchial asthma.
    British medical journal, 1974, Jan-19, Volume: 1, Issue:5898

    Topics: Acute Disease; Adenylyl Cyclases; Adolescent; Adrenergic alpha-Antagonists; Adult; Asthma; Drug Comb

1974
[Treatment of asthma].
    Revue medicale de Liege, 1973, Dec-01, Volume: 28, Issue:23

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Allergens; Anti-Bact

1973
Bronchial reactivity to inhaled histamine in asthmatic patients, before and after administration of atropine, phentolamine or disodium cromoglycate.
    Acta allergologica, 1974, Volume: 29, Issue:5

    Topics: Adult; Aerosols; Airway Obstruction; Airway Resistance; Asthma; Atropine; Bronchi; Cromolyn Sodium;

1974
[Effect of regitine on the excretion of 17-hydroxycorticosteroids in healthy subjects and in patients with allergic bronchial asthma].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1967, Oct-16, Volume: 22, Issue:42

    Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Asthma; Humans; Middle Ag

1967
Platelet aggregation in atopic and normal patients.
    The Journal of allergy and clinical immunology, 1973, Volume: 51, Issue:5

    Topics: Asthma; Bacterial Proteins; Caffeine; Cyclic AMP; Epinephrine; Humans; Hypersensitivity, Immediate;

1973
The effect of phentolamine on adenylate cyclase and on isoproterenol stimulation in leukocytes from asthmatic and nonasthmatic subjects.
    The Journal of allergy and clinical immunology, 1973, Volume: 52, Issue:3

    Topics: Adenine; Adenylyl Cyclases; Adolescent; Adult; Asthma; Child; Cyclic AMP; Drug Synergism; Humans; Hy

1973
[Asthma therapy with phentolamine].
    Acta allergologica, 1969, Volume: 24, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Aerosols; Asthma; Bronchial Spasm; Bronchodilator Agents; Female

1969
[Effect of DSCG on human bronchomotor activity in vitro].
    Respiration; international review of thoracic diseases, 1970, Volume: 27

    Topics: Adrenergic alpha-Antagonists; Asthma; Bronchi; Bronchial Spasm; Chromones; Constriction; Cromolyn So

1970
[Effect of regitine on the level of blood uric acid in patients with asthma].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1973, Jun-04, Volume: 28, Issue:23

    Topics: Asthma; Female; Humans; Male; Phentolamine; Uric Acid; Vanilmandelic Acid

1973
Exercise-induced bronchospasm: effect of adrenergic or cholinergic blockade.
    The Journal of allergy, 1967, Volume: 40, Issue:2

    Topics: Asthma; Atropine; Bronchial Spasm; Cardiovascular System; Child; Humans; Phentolamine; Physical Exer

1967