Page last updated: 2024-11-06

phentolamine and Arteriosclerosis

phentolamine has been researched along with Arteriosclerosis in 8 studies

Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.

Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's2 (25.00)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Speel, TG1
van Langen, H1
Wijkstra, H1
Meuleman, EJ1
Yasue, H1
Omote, S1
Takizawa, A1
Nagao, M1
Makhmudov, RM1
Dolgov, VV1
Voĭno-Iasenetskaia, TA1
Ivanov, VO1
Preobrazhenskiĭ, SN1
Henry, PD2
Yokoyama, M1
Heitzer, T1
Ylä-Herttuala, S1
Luoma, J1
Kurz, S1
Münzel, T1
Just, H1
Olschewski, M1
Drexler, H1
Park, K1
Goldstein, I1
Andry, C1
Siroky, MB1
Krane, RJ1
Azadzoi, KM1
Yamamoto, H1
Bossaller, C1
Cartwright, J1
Mikulicich, GF1
Oester, TY1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Influence of Treatment With the HMG-CoA-Reductase Inhibitor Fluvastatin on Erectile Function in Patients With Cardiovascular Risk-Factors and Erectile Dysfunction[NCT00382161]Phase 320 participants (Anticipated)Interventional2006-10-31Withdrawn (stopped due to not enough patients meeting inclusion criteria)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for phentolamine and Arteriosclerosis

ArticleYear
Coronary arterial spasm in ischemic heart disease and its pathogenesis. A review.
    Circulation research, 1983, Volume: 52, Issue:2 Pt 2

    Topics: Angina Pectoris, Variant; Animals; Arteriosclerosis; Autonomic Nervous System; Calcium; Calcium Chan

1983

Other Studies

7 other studies available for phentolamine and Arteriosclerosis

ArticleYear
Penile duplex pharmaco-ultrasonography revisited: revalidation of the parameters of the cavernous arterial response.
    The Journal of urology, 2003, Volume: 169, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Arteries; Arteriosclerosis; Blood Flow Velocity; Carotid

2003
[Effect of adrenaline on incorporation of 125I-LDL into the aorta].
    Kardiologiia, 1984, Volume: 24, Issue:8

    Topics: Animals; Aorta; Aortic Diseases; Arteriosclerosis; Chinchilla; Epinephrine; Lipoproteins, LDL; Male;

1984
Supersensitivity of atherosclerotic rabbit aorta to ergonovine. Mediation by a serotonergic mechanism.
    The Journal of clinical investigation, 1980, Volume: 66, Issue:2

    Topics: Animals; Aorta; Arteriosclerosis; Cholesterol; Diet, Atherogenic; Disease Models, Animal; Ergonovine

1980
Cigarette smoking potentiates endothelial dysfunction of forearm resistance vessels in patients with hypercholesterolemia. Role of oxidized LDL.
    Circulation, 1996, Apr-01, Volume: 93, Issue:7

    Topics: Acetylcholine; Adrenergic alpha-Antagonists; Arginine; Arteriosclerosis; Autoantibodies; Cardiovascu

1996
Vasculogenic female sexual dysfunction: the hemodynamic basis for vaginal engorgement insufficiency and clitoral erectile insufficiency.
    International journal of impotence research, 1997, Volume: 9, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Arteriosclerosis; Blood Pressure; Blood Vessels; Cholesterol;

1997
Videomicroscopic demonstration of defective cholinergic arteriolar vasodilation in atherosclerotic rabbit.
    The Journal of clinical investigation, 1988, Volume: 81, Issue:6

    Topics: Acetylcholine; Animals; Arterioles; Arteriosclerosis; Atropine; Blood Pressure; Dose-Response Relati

1988
The inhibition of the epinephrine--thyroxin induced arteriosclerosis by phentolamine.
    Angiology, 1970, Volume: 21, Issue:7

    Topics: Animals; Aorta; Arteriosclerosis; Cardiomyopathies; Epinephrine; Injections, Intravenous; Injections

1970