phentolamine has been researched along with Anaphylaxis in 16 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
Anaphylaxis: An acute hypersensitivity reaction due to exposure to a previously encountered ANTIGEN. The reaction may include rapidly progressing URTICARIA, respiratory distress, vascular collapse, systemic SHOCK, and death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The value of anaphylactic reaction of human smooth muscle displayed significant changes with the treatment of the muscles by agents selectively acting on the beta-adrenergic receptors of these organs." | 2.64 | [Reproduction of the anaphylactic reaction of isolated human smooth muscle organs and the effect of several adrenotropic substances]. ( Baranov, AP; Poriadin, GV, 1975) |
| " There is relatively poor clinician knowledge surrounding adrenaline reversal and a lack of easily accessible information available about dosing and drug location within the hospital." | 1.91 | Adrenaline auto-injector injuries: Practical considerations in emergency management in a tertiary hand surgery unit. ( Ellis, K; McCaughran, PW; Mosahebi, A; Nikkhah, D; Southall, C; Zargaran, D, 2023) |
| "Anaphylactic shock is sometimes life-threatening, and it is accompanied by hepatic venoconstriction in animals, which, in part, accounts for anaphylactic hypotension." | 1.39 | Alpha-adrenoceptor antagonists and chemical sympathectomy exacerbate anaphylaxis-induced hypotension, but not portal hypertension, in anesthetized rats. ( Kurata, Y; Shibamoto, T; Tanida, M; Wang, M, 2013) |
| "Pretreatment with reserpine prevented the restoration of blood pressure by all drugs." | 1.27 | The effects of meptazinol in comparison with pentazocine, morphine and naloxone in a rat model of anaphylactic shock. ( Paciorek, PM; Todd, MH; Waterfall, JF, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (87.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| McCaughran, PW | 1 |
| Ellis, K | 1 |
| Southall, C | 1 |
| Zargaran, D | 1 |
| Nikkhah, D | 1 |
| Mosahebi, A | 1 |
| Wang, M | 1 |
| Tanida, M | 1 |
| Shibamoto, T | 1 |
| Kurata, Y | 1 |
| Hand, JM | 1 |
| Will, JA | 1 |
| Buckner, CK | 1 |
| Iso, T | 1 |
| Uda, K | 1 |
| Yamauchi, H | 1 |
| Nakajima, N | 1 |
| Suda, H | 1 |
| Poriadin, GV | 1 |
| Baranov, AP | 1 |
| Holroyde, MC | 1 |
| Eyre, P | 3 |
| Fredholm, BB | 1 |
| Strandberg, K | 1 |
| Jian, M | 1 |
| Mu, J | 1 |
| Paciorek, PM | 1 |
| Todd, MH | 1 |
| Waterfall, JF | 1 |
| Hicks, R | 2 |
| Sackeyfio, AC | 2 |
| Bernauer, W | 1 |
| Liebig, R | 1 |
| Tuttle, RS | 1 |
| McCleary, M | 1 |
1 trial available for phentolamine and Anaphylaxis
| Article | Year |
|---|---|
[Reproduction of the anaphylactic reaction of isolated human smooth muscle organs and the effect of several adrenotropic substances].
Topics: Anaphylaxis; Appendix; Bronchi; Clinical Trials as Topic; Histamine Release; Humans; Immunization, P | 1975 |
15 other studies available for phentolamine and Anaphylaxis
| Article | Year |
|---|---|
Adrenaline auto-injector injuries: Practical considerations in emergency management in a tertiary hand surgery unit.
Topics: Anaphylaxis; Epinephrine; Hand; Humans; Injections, Intramuscular; Necrosis; Phentolamine | 2023 |
Alpha-adrenoceptor antagonists and chemical sympathectomy exacerbate anaphylaxis-induced hypotension, but not portal hypertension, in anesthetized rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Anaphylaxis; Animals; Hypertension, Portal; Hypotension; Li | 2013 |
Pharmacological alteration of antigen-induced contraction of pulmonary arteries isolated from the actively sensitized guinea pig.
Topics: Anaphylaxis; Animals; Antigens; Barium; Barium Compounds; Chlorides; Female; Guinea Pigs; Histamine; | 1982 |
Antianaphylactic effects of dipivalyl epinephrine and related compounds in rat conjunctiva.
Topics: Anaphylaxis; Animals; Conjunctiva; Epinephrine; Isoproterenol; Male; Norepinephrine; Phentolamine; P | 1980 |
Immunological release of histamine from bovine leucocytes. Unusual adrenergic modulation.
Topics: Anaphylaxis; Animals; Antigen-Antibody Reactions; Cattle; Dopamine; Epinephrine; Granulocytes; Hista | 1976 |
Some metabolic consequences of the anaphylactic reaction in the rabbit.
Topics: Adipose Tissue; Anaphylaxis; Animals; Blood Glucose; Electric Stimulation; Fatty Acids, Nonesterifie | 1975 |
Influence of adrenergic antagonist and naloxone on the anti-allergic shock effect of electro-acupuncture in mice.
Topics: Acupuncture Therapy; Anaphylaxis; Animals; Electric Stimulation; Female; Male; Mice; Mice, Inbred St | 1985 |
The study of the acupuncture effect on experimental allergic shock in mice.
Topics: Acupuncture Therapy; Anaphylaxis; Animals; Electric Stimulation Therapy; Female; Male; Mice; Mice, I | 1986 |
The effects of meptazinol in comparison with pentazocine, morphine and naloxone in a rat model of anaphylactic shock.
Topics: Anaphylaxis; Animals; Azepines; Blood Pressure; Decerebrate State; Electric Stimulation; Female; Hea | 1985 |
An interaction between exogenously administered anaphylatoxin and histamine in the guinea-pig.
Topics: Adrenalectomy; Anaphylaxis; Animals; Blood Pressure; Bronchi; Decerebrate State; Drug Interactions; | 1972 |
The nature of adrenergic mechanisms involved in anaphylatoxin activity in the guinea-pig.
Topics: Adrenalectomy; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anaphylaxis; Animals; Bloo | 1972 |
Plasma corticosteroid levels in anaphylactic shock of guinea pigs.
Topics: 11-Hydroxycorticosteroids; Acute Disease; Adrenergic alpha-Antagonists; Anaphylaxis; Animals; Guinea | 1973 |
Dopamine receptors in the pulmonary vein of the calf.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anaphylaxis; An | 1973 |
Release of dopamine from bovine lung by specific antigen and by compound 48-80.
Topics: Anaphylaxis; Animals; Antigens; Cattle; Dopamine; Horses; In Vitro Techniques; Lung; p-Methoxy-N-met | 1971 |
Centrally mediated and direct effects of anaphylaxis on cat vascular smooth muscle.
Topics: Anaphylaxis; Animals; Antigen-Antibody Reactions; Blood Pressure; Blood Vessels; Cats; Central Nervo | 1969 |