phentolamine has been researched along with Acute Respiratory Distress Syndrome in 7 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Boesing, M | 1 |
| Abig, K | 1 |
| Brändle, M | 1 |
| Brutsche, M | 1 |
| Burri, E | 1 |
| Frye, BC | 1 |
| Giezendanner, S | 1 |
| Grutters, JC | 1 |
| Haas, P | 1 |
| Heisler, J | 1 |
| Jaun, F | 1 |
| Leuppi-Taegtmeyer, AB | 1 |
| Lüthi-Corridori, G | 1 |
| Müller-Quernheim, J | 1 |
| Nüesch, R | 1 |
| Pohl, W | 1 |
| Rassouli, F | 1 |
| Leuppi, JD | 1 |
| Vora, A | 1 |
| Mehta, P | 1 |
| Arora, VK | 1 |
| Behera, D | 1 |
| Kar, A | 1 |
| Katiyar, SK | 1 |
| Samaria, JK | 1 |
| Koul, P | 1 |
| Jaychandra, A | 1 |
| Singh, BP | 1 |
| Kandi, S | 1 |
| Nazir Shah, N | 1 |
| Jain, NK | 1 |
| Najeeb, R | 1 |
| Ahmad, S | 1 |
| Najib, R | 1 |
| Faisal, M | 1 |
| Dewan, B | 1 |
| Arcaroli, J | 1 |
| Yang, KY | 1 |
| Yum, HK | 1 |
| Kupfner, J | 1 |
| Pitts, TM | 1 |
| Park, JS | 1 |
| Strassheim, D | 1 |
| Abraham, E | 1 |
| Liu, XW | 1 |
| Xu, Y | 1 |
| Zhou, T | 1 |
| Hua, Y | 1 |
| Wang, Z | 1 |
| Jin, Z | 1 |
| Radic, A | 1 |
| Simic, M | 1 |
| Tasic, M | 1 |
| Zivojnovic, S | 1 |
| Ni, H | 1 |
| Zhang, SJ | 1 |
| Zhang, RX | 1 |
| Shen, S | 1 |
| Yan, CH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Inhaled Aviptadil for the Treatment of COVID-19 in Patients at High Risk for ARDS: A Randomized, Placebo Controlled, Multicenter Trial[NCT04536350] | Phase 2 | 132 participants (Anticipated) | Interventional | 2021-05-18 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for phentolamine and Acute Respiratory Distress Syndrome
| Article | Year |
|---|---|
Inhaled aviptadil for the possible treatment of COVID-19 in patients at high risk for ARDS: study protocol for a randomized, placebo-controlled, and multicenter trial.
Topics: Adult; COVID-19; Drug Combinations; Humans; Multicenter Studies as Topic; Phentolamine; Randomized C | 2022 |
6 other studies available for phentolamine and Acute Respiratory Distress Syndrome
| Article | Year |
|---|---|
Aviptadil: A promising treatment option for acute respiratory distress syndrome.
Topics: Drug Combinations; Humans; Phentolamine; Respiratory Distress Syndrome; Vasoactive Intestinal Peptid | 2023 |
Effects of catecholamines on kinase activation in lung neutrophils after hemorrhage or endotoxemia.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-A | 2002 |
[Possible mechanism of the therapeutic effect of phentolamine in the adult respiratory distress syndrome--a preliminary study on oleic acid lung preparations].
Topics: Animals; Dogs; Hemodynamics; Oleic Acid; Oleic Acids; Phentolamine; Pulmonary Edema; Respiratory Dis | 1984 |
[Comparison of the effects of inhaled nitric oxide and intravasculare regitine on pulmonary gas exchange in young dogs with oleic-acid acute lung injury].
Topics: Animals; Antihypertensive Agents; Bronchodilator Agents; Dogs; Female; Infusions, Intravenous; Male; | 1998 |
[An experimental study of the effect of stimulation and blockage of the adrenergic system on the evolution of shock lung in dogs restored to normovolemia].
Topics: Animals; Blood Volume; Disease Models, Animal; Dogs; Female; Lung; Male; Norepinephrine; Phentolamin | 1989 |
[Changes in pulmonary arterial pressure during acute respiratory distress syndrome caused by injection of oleic acid in rabbits].
Topics: Animals; Antihypertensive Agents; Blood Pressure; Hexamethonium; Hexamethonium Compounds; Oleic Acid | 1986 |