phentolamine has been researched along with Acute Hypercapnic Respiratory Failure in 7 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Respiratory failure is a lethal complication of COVID-19 that has remained resistant to drug therapy." | 3.11 | The Use of IV Vasoactive Intestinal Peptide (Aviptadil) in Patients With Critical COVID-19 Respiratory Failure: Results of a 60-Day Randomized Controlled Trial. ( Fernandez, JP; Javitt, JC; Jayaweera, D; Lavin, P; Lee, RA; Lenhardt, R; Morganroth, ML; Park, DJ; Schoenfeld, DA; Youssef, JG, 2022) |
| "Phentolamine was then given, resulting in dramatic improvement." | 1.30 | Phentolamine improves clinical outcome after balloon valvoplasty in neonates with severe pulmonary stenosis. ( Dzimiri, N; Galal, O; Kalloghlian, A; Pittappilly, BM, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Youssef, JG | 1 |
| Lavin, P | 1 |
| Schoenfeld, DA | 1 |
| Lee, RA | 1 |
| Lenhardt, R | 1 |
| Park, DJ | 1 |
| Fernandez, JP | 1 |
| Morganroth, ML | 1 |
| Javitt, JC | 1 |
| Jayaweera, D | 1 |
| MAZZONE, O | 1 |
| BLASI, A | 1 |
| Galal, O | 1 |
| Kalloghlian, A | 1 |
| Pittappilly, BM | 1 |
| Dzimiri, N | 1 |
| James, TN | 1 |
| Isobe, JH | 1 |
| Urthaler, F | 1 |
| Pittet, JF | 1 |
| Lacroix, JS | 1 |
| Gunning, K | 1 |
| Laverriere, MC | 1 |
| Morel, DR | 1 |
| Suter, PM | 1 |
| Váczy, L | 1 |
| Lenner, A | 1 |
| Molnár, A | 1 |
| Maritano, M | 1 |
| Cabrai, M | 1 |
| Pattono, R | 1 |
| Marchiaro, G | 1 |
1 trial available for phentolamine and Acute Hypercapnic Respiratory Failure
| Article | Year |
|---|---|
The Use of IV Vasoactive Intestinal Peptide (Aviptadil) in Patients With Critical COVID-19 Respiratory Failure: Results of a 60-Day Randomized Controlled Trial.
Topics: COVID-19 Drug Treatment; Drug Combinations; Humans; Interleukin-6; Oxygen; Phentolamine; Respiratory | 2022 |
6 other studies available for phentolamine and Acute Hypercapnic Respiratory Failure
| Article | Year |
|---|---|
[ACTION OF A SYMPATHOLYTIC DRUG ON CHANGES IN THE CAPILLAROSCOPIC PICTURE CAUSED BY SPARTEINE].
Topics: Bronchial Diseases; Capillaries; Cardiovascular System; Heart Failure; Pharmacology; Phentolamine; R | 1963 |
Phentolamine improves clinical outcome after balloon valvoplasty in neonates with severe pulmonary stenosis.
Topics: Adrenergic alpha-Antagonists; Catheterization; Follow-Up Studies; Humans; Infant; Infant, Newborn; I | 1999 |
Analysis of components in a cardiogenic hypertensive chemoreflex.
Topics: Animals; Atropine; Blood Pressure; Bradycardia; Cardiovascular System; Chemoreceptor Cells; Coronary | 1975 |
Prostacyclin but not phentolamine increases oxygen consumption and skin microvascular blood flow in patients with sepsis and respiratory failure.
Topics: Adult; Aged; Bacterial Infections; Epoprostenol; Female; Hemodynamics; Humans; Male; Microcirculatio | 1990 |
Treatment of pregnancy toxaemia with alpha-blocking agents.
Topics: Adrenergic alpha-Antagonists; Adult; Brain; Capillary Permeability; Eclampsia; Female; Humans; Hyper | 1971 |
[Apropos of various vascular and respiratory manifestations with the use of adrenolytic substances during hyperbaric oxygenation in rats].
Topics: Animals; Blood Circulation; Chlorpromazine; Ergoloid Mesylates; Hyperbaric Oxygenation; Hypothalamus | 1966 |