phentolamine has been researched along with Abnormalities, Drug-Induced in 3 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The frequency of hemimelia and micromelia, and of bilateral involvement, was greater in litters exposed to the high pH acetazolamide or the epinephrine-acetazolamide combinations, and was reduced by phentolamine or adrenal medullectomy." | 1.26 | Potentiation by the injection vehicle of the teratological action of acetazolamide in rats. ( Jones, JC; Muther, TF; Smoak, NS, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ismail, M | 1 |
| Ellison, AC | 1 |
| Tilmisany, AK | 1 |
| Cameron, RH | 1 |
| Kolesari, GL | 1 |
| Kalbfleisch, JH | 1 |
| Muther, TF | 1 |
| Jones, JC | 1 |
| Smoak, NS | 1 |
3 other studies available for phentolamine and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Teratogenicity in the rat of the venom from the scorpion Androctonus amoreuxi (Aud. & Sav.).
Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Female; Fetus; Insulin; Insulin Secretion; Mal | 1983 |
Pharmacology of dextroamphetamine-induced cardiovascular malformations in the chick embryo.
Topics: Abnormalities, Drug-Induced; alpha-Methyltyrosine; Animals; Chick Embryo; Dextroamphetamine; Heart D | 1983 |
Potentiation by the injection vehicle of the teratological action of acetazolamide in rats.
Topics: Abnormalities, Drug-Induced; Acetazolamide; Adrenal Medulla; Animals; Drug Synergism; Ectromelia; Ep | 1977 |