Page last updated: 2024-11-02

phentermine and Blood Pressure, High

phentermine has been researched along with Blood Pressure, High in 10 studies

Phentermine: A central nervous system stimulant and sympathomimetic with actions and uses similar to those of DEXTROAMPHETAMINE. It has been used most frequently in the treatment of obesity.

Research Excerpts

ExcerptRelevanceReference
"There is a perception that phentermine pharmacotherapy for obesity increases blood pressure and heart rate (HR), exposing treated patients to increased cardiovascular risk."7.77Blood pressure and heart rate effects, weight loss and maintenance during long-term phentermine pharmacotherapy for obesity. ( Greenway, FL; Gupta, AK; Hendricks, EJ; Westman, EC, 2011)
"In people with elevated blood pressure, orlistat, phentermine/topiramate and naltrexone/bupropion reduced body weight; the magnitude of the effect was greatest with phentermine/topiramate."5.12Long-term effects of weight-reducing drugs in people with hypertension. ( Berghold, A; Horvath, K; Jeitler, K; Krenn, C; Semlitsch, T; Siebenhofer, A; Winterholer, S, 2021)
"There is a perception that phentermine pharmacotherapy for obesity increases blood pressure and heart rate (HR), exposing treated patients to increased cardiovascular risk."3.77Blood pressure and heart rate effects, weight loss and maintenance during long-term phentermine pharmacotherapy for obesity. ( Greenway, FL; Gupta, AK; Hendricks, EJ; Westman, EC, 2011)
"Nineteen participants, all of whom had hypertension, were being treated with fenfluramine or dexfenfluramine (5 on these agents alone, 14 also with phentermine)."3.71Appetite suppressants and valvular heart disease in a population-based sample: the HyperGEN study. ( Arnett, DK; Bella, JN; de Simone, G; Devereux, RB; Hopkins, PN; Kitzman, DW; Liu, JE; Morgan, D; Oberman, A; Palmieri, V; Roman, MJ, 2002)
"To evaluate, in compliant patients, the pharmaceutical costs of treating obesity with fenfluramine/mazindol, fenfluramine/phentermine, caffeine/ephedrine, or mazindol relative to the pharmaceutical costs of treating obesity-related comorbid conditions and reducing cardiovascular risk."3.70Pharmaceutical cost savings of treating obesity with weight loss medications. ( Bray, GA; Greenway, FL; Rood, JC; Ryan, DH; Smith, SR; Tucker, EW, 1999)
"Hypertension is a major risk factor for cardiovascular and renal diseases in the United States and worldwide."2.72Weight-Loss Strategies for Prevention and Treatment of Hypertension: A Scientific Statement From the American Heart Association. ( Ard, JD; Cohen, JB; Egan, BM; Hall, JE; Hall, ME; Lavie, CJ; Ma, J; Ndumele, CE; Schauer, PR; Shimbo, D, 2021)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's2 (20.00)18.2507
2000's2 (20.00)29.6817
2010's2 (20.00)24.3611
2020's3 (30.00)2.80

Authors

AuthorsStudies
Hall, ME1
Cohen, JB1
Ard, JD1
Egan, BM1
Hall, JE1
Lavie, CJ1
Ma, J1
Ndumele, CE1
Schauer, PR1
Shimbo, D1
Siebenhofer, A2
Winterholer, S1
Jeitler, K2
Horvath, K2
Berghold, A2
Krenn, C1
Semlitsch, T2
Chua, MWJ1
Lai, BC1
Posch, N1
Meschik, J1
Hendricks, EJ1
Greenway, FL2
Westman, EC1
Gupta, AK1
Stephens, LC1
Katz, SG1
Derby, LE1
Myers, MW1
Jick, H1
Ryan, DH1
Bray, GA1
Rood, JC1
Tucker, EW1
Smith, SR1
Palmieri, V1
Arnett, DK1
Roman, MJ1
Liu, JE1
Bella, JN1
Oberman, A1
Kitzman, DW1
Hopkins, PN1
Morgan, D1
de Simone, G1
Devereux, RB1
Hoyer, I1
Van Zwieten, PA1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Long-term Phentermine Pharmacotherapy: An Investigation for Symptoms of Dependence, Cravings, or Withdrawal[NCT01402674]269 participants (Actual)Interventional2011-08-31Completed
[NCT00005267]3,604 participants (Actual)Observational1995-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for phentermine and Blood Pressure, High

ArticleYear
Weight-Loss Strategies for Prevention and Treatment of Hypertension: A Scientific Statement From the American Heart Association.
    Hypertension (Dallas, Tex. : 1979), 2021, Volume: 78, Issue:5

    Topics: American Heart Association; Anti-Obesity Agents; Appetite Depressants; Bariatric Surgery; Exercise;

2021
Long-term effects of weight-reducing drugs in people with hypertension.
    The Cochrane database of systematic reviews, 2021, 01-17, Volume: 1

    Topics: Adult; Anti-Obesity Agents; Appetite Depressants; Bias; Blood Pressure; Body Weight; Bupropion; Diet

2021
Long-term effects of weight-reducing drugs in people with hypertension.
    The Cochrane database of systematic reviews, 2016, Mar-02, Volume: 3

    Topics: Adult; Anti-Obesity Agents; Appetite Depressants; Blood Pressure; Cyclobutanes; Diet, Reducing; Fema

2016

Other Studies

7 other studies available for phentermine and Blood Pressure, High

ArticleYear
Phentermine-Induced Acute Kidney Injury Secondary to Uncontrolled Hypertension in a Patient with Weight Regain Post-bariatric Surgery.
    Obesity surgery, 2021, Volume: 31, Issue:8

    Topics: Acute Kidney Injury; Bariatric Surgery; Humans; Hypertension; Obesity, Morbid; Phentermine; Weight G

2021
Blood pressure and heart rate effects, weight loss and maintenance during long-term phentermine pharmacotherapy for obesity.
    Obesity (Silver Spring, Md.), 2011, Volume: 19, Issue:12

    Topics: Adult; Anti-Obesity Agents; Blood Pressure; Cohort Studies; Diet, Carbohydrate-Restricted; Diet, Ket

2011
Phentermine and anaesthesia.
    Anaesthesia and intensive care, 2005, Volume: 33, Issue:4

    Topics: Alfentanil; Androstanols; Anesthesia; Anesthetics, Intravenous; Appetite Depressants; Blood Pressure

2005
Use of dexfenfluramine, fenfluramine and phentermine and the risk of stroke.
    British journal of clinical pharmacology, 1999, Volume: 47, Issue:5

    Topics: Aged; Appetite Depressants; Body Mass Index; Case-Control Studies; Cerebrovascular Disorders; Cohort

1999
Pharmaceutical cost savings of treating obesity with weight loss medications.
    Obesity research, 1999, Volume: 7, Issue:6

    Topics: Adolescent; Adult; Appetite Depressants; Caffeine; Cardiovascular Diseases; Diabetes Mellitus; Drug

1999
Appetite suppressants and valvular heart disease in a population-based sample: the HyperGEN study.
    The American journal of medicine, 2002, Jun-15, Volume: 112, Issue:9

    Topics: Aortic Valve Insufficiency; Appetite Depressants; Dexfenfluramine; Drug Combinations; Female; Fenflu

2002
The central hypotensive action of amphetamine, ephedrine, phentermine, chlorphentermine and fenfluramine.
    The Journal of pharmacy and pharmacology, 1972, Volume: 24, Issue:6

    Topics: Amphetamine; Animals; Appetite Depressants; Blood Pressure; Cats; Chlorphentermine; Depression, Chem

1972