phenprocoumon and Endometritis

Reported in this paper is a favourable side-effect of heparin-falithrome prophylaxis used to minimise the risk of thromboembolism to women in puerperium with pronounced varicosis or with a record of thromboembolism. Incidence of impaired involution of the uterus in puerperium, lochial congestion, endometritis, and, consequently, genitally caused fever in patients exposed to heparin action was found to be lower with significance than it had been among puerperal patients without such prophylaxis. The possible mechanism underlying that favourable side-effect, not reported elsewhere in the past, is discussed in greater detail in this paper.

Topics: 4-Hydroxycoumarins; Anticoagulants; Drug Therapy, Combination; Endometritis; Female; Heparin; Humans; Phenprocoumon; Pregnancy; Puerperal Disorders; Thromboembolism; Uterus