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phenoxybenzamine and Ventricular Fibrillation

phenoxybenzamine has been researched along with Ventricular Fibrillation in 9 studies

Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.

Ventricular Fibrillation: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.

Research Excerpts

ExcerptRelevanceReference
"Death in ventricular fibrillation was induced consistently in desoxycorticosterone acetate-pretreated rats by the beta-adrenergic agonist isoproterenol but not by norepinephrine or epinephrine, both of which possess alpha- as well as beta-adrenergic activity."3.66Role of alpha- and beta-adrenergic activation in ventricular fibrillation death of corticoid-pretreated rats. ( Green, M; Guideri, G; Lehr, D, 1980)
"Ventricular fibrillation was electrically induced in 60 rats and the effects of adrenergic stimulation ad blockade on the time taken to spontaneous reversion to sinus rhythm were determined."1.27Effect of adrenergic stimulation and blockade on ventricular defibrillation in the rat. ( Huerta, FI; Sharma, AD; Waxman, MB, 1983)
"Ventricular fibrillation was induced electrically with a bipolar electrode catheter placed in the right ventricle."1.25Hemodynamic effects of ventricular defibrillation. ( Abboud, FM; Pansegrau, DG, 1970)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19909 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
VARMA, DR1
GILLIS, RA1
MELVILLE, KI1
Green, M1
Guideri, G1
Lehr, D1
Sharma, AD1
Waxman, MB1
Huerta, FI1
Sagar, KB1
Hanson, EC1
Powell, WJ1
Sono, K1
Kurahashi, K1
Fujiwara, M1
Pansegrau, DG1
Abboud, FM1
Nakano, J1
Mercer, GR1
Chiba, S1
Hashimoto, K2
Papp, JG1
Szekeres, L1

Other Studies

9 other studies available for phenoxybenzamine and Ventricular Fibrillation

ArticleYear
On the relationship of catecholamines and thyroid activity to ventricular fibrillation during hypothermia in dogs.
    Canadian journal of biochemistry and physiology, 1963, Volume: 41

    Topics: Animals; Antithyroid Agents; Catecholamines; Dogs; Epinephrine; Hypothermia; Hypothermia, Induced; I

1963
Role of alpha- and beta-adrenergic activation in ventricular fibrillation death of corticoid-pretreated rats.
    Journal of pharmaceutical sciences, 1980, Volume: 69, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aminophylline; Animals; Catecholamines; Desoxyc

1980
Effect of adrenergic stimulation and blockade on ventricular defibrillation in the rat.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:3

    Topics: Albuterol; Animals; Atropine; Isoproterenol; Male; Metoprolol; Norepinephrine; Phenoxybenzamine; Phe

1983
Neurogenic coronary vasoconstrictor effects of digitalis during acute global ischemia in dogs.
    The Journal of clinical investigation, 1977, Volume: 60, Issue:6

    Topics: Animals; Coronary Circulation; Coronary Disease; Coronary Vessels; Digoxin; Dogs; Phenoxybenzamine;

1977
Changes in the incidence and duration of ventricular fibrillation in dependence on the extraneuronal accumulation of isoprenaline in the perfused rat heart.
    Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 331, Issue:1

    Topics: Animals; Catechol O-Methyltransferase Inhibitors; Electric Stimulation; Female; Heart Rate; In Vitro

1985
Hemodynamic effects of ventricular defibrillation.
    The Journal of clinical investigation, 1970, Volume: 49, Issue:2

    Topics: Animals; Atropine; Blood Pressure; Bradycardia; Carbon Dioxide; Cardiac Output; Dogs; Dye Dilution T

1970
Circulatory effect of ventricular fibrillation.
    Acta cardiologica, 1965, Volume: 20, Issue:6

    Topics: Animals; Blood Circulation; Cardiac Output; Dogs; Electric Countershock; Heart Massage; Phenoxybenza

1965
Ventricular fibrillation induced by saxitoxin into the AV node artery and its prevention by phenoxybenzamine.
    The Tohoku journal of experimental medicine, 1969, Volume: 99, Issue:1

    Topics: Animals; Dogs; Electrocardiography; Heart Conduction System; Injections, Intra-Arterial; Phenoxybenz

1969
Analysis of the mechanism of adrenergic actions on ventricular vulnerability.
    European journal of pharmacology, 1968, Volume: 3, Issue:1

    Topics: Amino Alcohols; Anesthesia; Animals; Carotid Arteries; Dogs; Electric Stimulation; Electrophysiology

1968